Research Topics
Species | ALLISON REISSSummaryAffiliation: Winthrop University Hospital Country: USA Publications
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Detail Information
Publications
Regulation of cerebral cholesterol metabolism in Alzheimer diseaseAllison B Reiss
Winthrop Research Institute, Department of Medicine, Winthrop University Hospital, Mineola, NY 11501, USA
J Investig Med 60:576-82. 2012..This review summarizes the current state of our knowledge of the influence of cholesterol and lipid pathways in AD pathogenesis in vitro and in vivo...
Effect of cyclooxygenase inhibition on cholesterol efflux proteins and atheromatous foam cell transformation in THP-1 human macrophages: a possible mechanism for increased cardiovascular riskEdwin S L Chan
Division of Clinical Pharmacology, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA
Arthritis Res Ther 9:R4. 2007..NS398-treated THP-1 macrophages show greater vulnerability to form foam cells. Increased cardiovascular risk with COX inhibition may be ascribed at least in part to altered cholesterol metabolism...
Effects of inflammation on cholesterol metabolism: impact on systemic lupus erythematosusAllison B Reiss
Vascular Biology Institute, Department of Medicine, Winthrop University Hospital, Suite 502, Mineola, NY 11501, USA
Curr Rheumatol Rep 11:255-60. 2009..The impact of lupus on each of these components of the cholesterol flux pathways is discussed. The formation of autoantibodies against epitopes within lipoprotein particles and their controversial role in atherogenesis is addressed...
Lectin-like oxidized low density lipoprotein receptor 1 (LOX-1) in atherogenesis: a brief reviewAllison B Reiss
Vascular Biology Institute, Department of Medicine, Winthrop University Hospital, Suite 502, Mineola, NY 11501, USA
Curr Med Chem 16:2641-52. 2009..The ability of LOX-1 to bind many different ligands and control several atherogenic processes makes this receptor a likely vascular disease biomarker as well as an ideal choice for drug therapy aimed at preventing cardiovascular disease...
Plasma from systemic lupus patients compromises cholesterol homeostasis: a potential mechanism linking autoimmunity to atherosclerotic cardiovascular diseaseAllison B Reiss
Department of Medicine, Vascular Biology Institute, Division of Rheumatology, Allergy and Immunology, Winthrop University Hospital, 222 Station Plaza, North, Suite 502, Mineola, NY 11501, USA
Rheumatol Int 30:591-8. 2010..001). Impaired cholesterol homeostasis in SLE provides further evidence of immune involvement in atherogenesis. Strategies to inhibit or reverse arterial cholesterol accumulation may benefit SLE patients...
Statins in neurological disorders: mechanisms and therapeutic valueAllison B Reiss
Vascular Biology Institute and 2Division of Neurology, Department of Medicine, Winthrop University Hospital, Mineola, New York, USA
ScientificWorldJournal 9:1242-59. 2009..In this review, we discuss the potential reasons for the effect of statins on stroke and AD, and the multiple mechanisms of action of this class of lipid-lowering drugs...
Enhanced CD36 scavenger receptor expression in THP-1 human monocytes in the presence of lupus plasma: linking autoimmunity and atherosclerosisAllison B Reiss
Vascular Biology Institute, Department of Medicine, Winthrop University Hospital, 222 Station Plaza, North, Suite 502, Mineola, NY 11501, USA
Exp Biol Med (Maywood) 234:354-60. 2009..CD36 may provide a novel therapeutic target in the treatment of ASCVD in SLE patients...
Atheroprotective effects of methotrexate on reverse cholesterol transport proteins and foam cell transformation in human THP-1 monocyte/macrophagesAllison B Reiss
Vascular Biology Institute, Winthrop University Hospital, Mineola, New York 11501, USA
Arthritis Rheum 58:3675-83. 2008....
Role of HMG-CoA reductase inhibitors in neurological disorders : progress to dateAllison B Reiss
SUNY Stony Brook School of Medicine, Vascular Biology Institute, Winthrop University Hospital, Mineola, NY 11501, USA
Drugs 67:2111-20. 2007..The appropriateness of initiating statin therapy for neurological disorders is not established at this time. The exception is stroke, in which recurrence is significantly reduced by statin therapy...
Disruption of cholesterol efflux by coxib medications and inflammatory processes: link to increased cardiovascular riskAllison B Reiss
Vascular Biology Institute, Department of Medicine, Winthrop University Hospital, Mineola, NY, and Department of Medicine, NYU School of Medicine, New York, NY, USA
J Investig Med 57:695-702. 2009..We explore the relationship between suppression of reverse cholesterol transport and harmful cardiac effects of coxibs...
PPARgamma activity in the vessel wall: anti-atherogenic propertiesAllison B Reiss
Vascular Biology Institute, Department of Medicine, Winthrop University Hospital, 222 Station Plaza North, Mineola, NY 11501, USA
Curr Med Chem 13:3227-38. 2006..We provide an overview of in vitro and in vivo data in cell lines, animal models, and humans demonstrating the ways in which PPARgamma activation alters the biology of the arterial wall...
Recent insights into the role of prostanoids in atherosclerotic vascular diseaseAllison B Reiss
Department of Medicine, Vascular Biology Institute, Winthrop University Hospital, 222 Station Plaza, North Mineola, NY 11501, USA
Curr Vasc Pharmacol 4:395-408. 2006..Finally, we investigate original therapeutic modalities of various prostanoids involved in the aforementioned diseases...
Atherosclerosis: immune and inflammatory aspectsAllison B Reiss
Vascular Biology Institute, Winthrop University Hospital, 222 Station Plaza, North, Suite 511 A, Mineola, NY 11501, USA
J Investig Med 54:123-31. 2006..Emphasis is placed on the role of inflammation as a driving force in the process of atherosclerosis and vascular endothelium as a modulating factor in the pathogenesis of coronary artery disease...
Interferon-gamma impedes reverse cholesterol transport and promotes foam cell transformation in THP-1 human monocytes/macrophagesAllison B Reiss
Department of Vascular Biology, Winthrop University Hospital, Mineola, NY 11501, USA
Med Sci Monit 10:BR420-5. 2004..We therefore examined the effect of IFN-g on macrophage foam cell formation and on expression of the anti-atherogenic 27-hydroxylase in THP-1 human monocytes/macrophages...
Adenosine A2A receptor occupancy stimulates expression of proteins involved in reverse cholesterol transport and inhibits foam cell formation in macrophagesAllison B Reiss
Department of Medicine, New York University School of Medicine, New York, NY, USA
J Leukoc Biol 76:727-34. 2004..These findings suggest a novel approach to the development of agents that prevent progression of atherosclerosis...
A2A adenosine receptor stimulation decreases foam cell formation by enhancing ABCA1-dependent cholesterol effluxTaiese Crystal Bingham
Department of Medicine, New York University School of Medicine, New York, New York, USA
J Leukoc Biol 87:683-90. 2010..0007 vs. control; n=3) and phospho-ABCA1 (13+5%; P<0.0003 vs. control; n=3) protein. These results demonstrate that A2AR occupancy diminishes foam cell formation by stimulating increased reverse cholesterol transport via ABCA1...
Cholesterol 27-hydroxylase but not apolipoprotein apoE contributes to A2A adenosine receptor stimulated reverse cholesterol transportTaiese Crystal Bingham
Department of Medicine, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
Inflammation 35:49-57. 2012..These results demonstrate that adenosine A(2A) receptor occupancy diminishes foam cell formation by increasing expression and function of CYP27A1...
Cholesterol in neurologic disorders of the elderly: stroke and Alzheimer's diseaseAllison B Reiss
Department of Medicine, New York University School of Medicine, New Bellevue 16N1, 550 First Avenue, New York, NY 10016, USA
Neurobiol Aging 25:977-89. 2004..The reduction in stroke and AD risk in patients treated with cholesterol-lowering statins is also discussed...
Cholesterol and apolipoprotein E in Alzheimer's diseaseAllison B Reiss
Vascular Biology Institute, Department of Medicine, Winthrop-University Hospital, Mineola, New York, USA
Am J Alzheimers Dis Other Demen 20:91-6. 2005..ApoE, which transports cholesterol throughout the brain, exhibits an isoform-specific association with AD such that the E4 isoform, by unknown mechanisms, shifts the onset curve toward an earlier age...
Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosisEdwin S L Chan
Division of Clinical Pharmacology, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA
Br J Pharmacol 148:1144-55. 2006..6. These results demonstrate that hepatic adenosine A(2A) receptors play an active role in the pathogenesis of hepatic fibrosis, and suggest a novel therapeutic target in the treatment and prevention of hepatic cirrhosis...
Oxysterol derivatives of cholesterol in neurodegenerative disordersT M Jeitner
Department of Medicine, Winthrop University Hospital, 222 Station Plaza, North, Suite 502, Mineola, NY 11501, USA
Curr Med Chem 18:1515-25. 2011..The following article provides an overview of the involvement of oxysterols in Alzheimer's disease, multiple sclerosis and spastic paraplegias...
Differential expression of cholesterol hydroxylases in Alzheimer's diseaseJames Brown
Departments of Pharmacology and Pathology, Loyola University Medical Center, Maywood, IL 60153, USA
J Biol Chem 279:34674-81. 2004....
Research Grants
- Immune Reactants, Cholesterol and AtherosclerosisALLISON REISS; Fiscal Year: 2006..abstract_text> ..
