K J Wilson
- Synthesis of thiophene-2-carboxamidines containing 2-aminothiazoles and their biological evaluation as urokinase inhibitorsK J Wilson
3 Dimensional Pharmaceuticals, Inc, Exton, PA 19341, USA
Bioorg Med Chem Lett 11:915-8. 2001..Further optimization of this series by substitution of the terminal amine yielded urokinase inhibitors with excellent activities...
- Structure-based design, synthesis and SAR of a novel series of thiopheneamidine urokinase plasminogen activator inhibitorsN L Subasinghe
3 Dimensional Pharmaceuticals Inc, 665 Stockton Drive, Exton, PA 19341, USA
Bioorg Med Chem Lett 11:1379-82. 2001..Further structure based elaboration of this residue resulted in a novel class of potent and selective inhibitors of uPA...