E S Onaivi

Summary

Affiliation: William Paterson University
Country: USA

Publications

  1. pmc Consequences of cannabinoid and monoaminergic system disruption in a mouse model of autism spectrum disorders
    E S Onaivi
    William Paterson University, Wayne, USA
    Curr Neuropharmacol 9:209-14. 2011
  2. pmc Commentary: Functional Neuronal CB2 Cannabinoid Receptors in the CNS
    E S Onaivi
    William Paterson University, Wayne NJ and Molecular Neurobiology Branch, National Institute on Drug Abuse, NIH, Baltimore, USA
    Curr Neuropharmacol 9:205-8. 2011
  3. pmc CNS effects of CB2 cannabinoid receptors: beyond neuro-immuno-cannabinoid activity
    Emmanuel S Onaivi
    Department of Biology, William Paterson University, Wayne, NJ 07470, USA
    J Psychopharmacol 26:92-103. 2012
  4. pmc Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: from mice to human subjects
    Emmanuel S Onaivi
    Department of Biology, William Paterson University, Wayne, New Jersey, USA
    PLoS ONE 3:e1640. 2008
  5. doi request reprint Behavioral effects of CB2 cannabinoid receptor activation and its influence on food and alcohol consumption
    E S Onaivi
    Department of Biology, William Paterson University, Wayne, New Jersey, USA
    Ann N Y Acad Sci 1139:426-33. 2008
  6. ncbi request reprint Neuropsychobiological evidence for the functional presence and expression of cannabinoid CB2 receptors in the brain
    Emmanuel S Onaivi
    Department of Biology, William Paterson University, Wayne, NJ 07470, USA
    Neuropsychobiology 54:231-46. 2006
  7. ncbi request reprint Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain
    Emmanuel S Onaivi
    Department of Biology, William Paterson University, Wayne, NJ 07470, USA
    Ann N Y Acad Sci 1074:514-36. 2006
  8. ncbi request reprint Functional expression of brain neuronal CB2 cannabinoid receptors are involved in the effects of drugs of abuse and in depression
    Emmanuel S Onaivi
    Department of Biology, William Paterson University, Wayne, New Jersey, USA
    Ann N Y Acad Sci 1139:434-49. 2008
  9. doi request reprint An endocannabinoid hypothesis of drug reward and drug addiction
    Emmanuel S Onaivi
    Department of Biology, William Paterson University, Wayne, New Jersey, USA
    Ann N Y Acad Sci 1139:412-21. 2008
  10. pmc Species differences in cannabinoid receptor 2 (CNR2 gene): identification of novel human and rodent CB2 isoforms, differential tissue expression and regulation by cannabinoid receptor ligands
    Q R Liu
    Mol Neurobiol Branch, NIDA IRP, NIH, Baltimore, MD, USA
    Genes Brain Behav 8:519-30. 2009

Collaborators

Detail Information

Publications20

  1. pmc Consequences of cannabinoid and monoaminergic system disruption in a mouse model of autism spectrum disorders
    E S Onaivi
    William Paterson University, Wayne, USA
    Curr Neuropharmacol 9:209-14. 2011
    ..Our data provides a basis for further studies in evaluating the role of the cannabinoid and monoaminergic systems in the etiology of ASDs...
  2. pmc Commentary: Functional Neuronal CB2 Cannabinoid Receptors in the CNS
    E S Onaivi
    William Paterson University, Wayne NJ and Molecular Neurobiology Branch, National Institute on Drug Abuse, NIH, Baltimore, USA
    Curr Neuropharmacol 9:205-8. 2011
    ..While the issue of the specificity of CB2-R antibodies remains, many recent studies have reported the discovery and functional characterization of functional neuronal CB2-Rs in the CNS beyond neuro-immuno cannabinoid activity...
  3. pmc CNS effects of CB2 cannabinoid receptors: beyond neuro-immuno-cannabinoid activity
    Emmanuel S Onaivi
    Department of Biology, William Paterson University, Wayne, NJ 07470, USA
    J Psychopharmacol 26:92-103. 2012
    ....
  4. pmc Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: from mice to human subjects
    Emmanuel S Onaivi
    Department of Biology, William Paterson University, Wayne, New Jersey, USA
    PLoS ONE 3:e1640. 2008
    ..Therefore, neuronal expression of CB2-Rs had been ambiguous and controversial and its role in depression and substance abuse is unknown...
  5. doi request reprint Behavioral effects of CB2 cannabinoid receptor activation and its influence on food and alcohol consumption
    E S Onaivi
    Department of Biology, William Paterson University, Wayne, New Jersey, USA
    Ann N Y Acad Sci 1139:426-33. 2008
    ..These effects of CB2 cannabinoid receptor ligands in in vivo behavioral tests are provided as functional evidence that CB2-Rs in the brain play a role in food and alcohol consumption and in the modification of mouse behavior...
  6. ncbi request reprint Neuropsychobiological evidence for the functional presence and expression of cannabinoid CB2 receptors in the brain
    Emmanuel S Onaivi
    Department of Biology, William Paterson University, Wayne, NJ 07470, USA
    Neuropsychobiology 54:231-46. 2006
    ..This multifocal expression of iCB2 in the brain suggests that CB2 receptors may play broader roles than previously anticipated and may therefore be exploited as new targets in the treatment of depression and substance abuse...
  7. ncbi request reprint Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain
    Emmanuel S Onaivi
    Department of Biology, William Paterson University, Wayne, NJ 07470, USA
    Ann N Y Acad Sci 1074:514-36. 2006
    ....
  8. ncbi request reprint Functional expression of brain neuronal CB2 cannabinoid receptors are involved in the effects of drugs of abuse and in depression
    Emmanuel S Onaivi
    Department of Biology, William Paterson University, Wayne, New Jersey, USA
    Ann N Y Acad Sci 1139:434-49. 2008
    ..Our data demonstrate the functional expression of CB2-Rs in the brain that may provide novel targets for the effects of cannabinoids in depression and substance abuse disorders beyond neuroimmunocannabinoid activity...
  9. doi request reprint An endocannabinoid hypothesis of drug reward and drug addiction
    Emmanuel S Onaivi
    Department of Biology, William Paterson University, Wayne, New Jersey, USA
    Ann N Y Acad Sci 1139:412-21. 2008
    ..The results suggest that the EPCS may be an important natural regulatory mechanism for drug reward and a target for the treatment of addictive disorders...
  10. pmc Species differences in cannabinoid receptor 2 (CNR2 gene): identification of novel human and rodent CB2 isoforms, differential tissue expression and regulation by cannabinoid receptor ligands
    Q R Liu
    Mol Neurobiol Branch, NIDA IRP, NIH, Baltimore, MD, USA
    Genes Brain Behav 8:519-30. 2009
    ..These results provide much improved information about CB2 gene structure and its human and rodent variants that should be considered in developing CB2-R-based therapeutic agents...
  11. ncbi request reprint Human cannabinoid receptor 1: 5' exons, candidate regulatory regions, polymorphisms, haplotypes and association with polysubstance abuse
    P W Zhang
    Molecular Neurobiology Branch, National Institute on Drug Abuse IRP NIH, Baltimore, MD 21224, USA
    Mol Psychiatry 9:916-31. 2004
    ..Post-mortem brain samples of heterozygous individuals contain less mRNA transcribed from the TAG alleles than from other CB1/Cnr1 haplotypes. CB1/ Cnr1 genomic variation thus appears to play roles in human addiction vulnerability...
  12. ncbi request reprint Ibogaine signals addiction genes and methamphetamine alteration of long-term potentiation
    Emmanuel S Onaivi
    Department of Biology, William Paterson University, Wayne, New Jersey 07470, USA
    Ann N Y Acad Sci 965:28-46. 2002
    ..It is therefore tempting to suggest that ibogaine signals addiction gene products...
  13. ncbi request reprint Endocannabinoids and cannabinoid receptor genetics
    Emmanuel S Onaivi
    Department of Biology, William Paterson University, 07470, Wayne, NJ, USA
    Prog Neurobiol 66:307-44. 2002
    ..Therefore, understanding the physiological cannabinoid control system in the human body and brain will contribute to elucidating this natural regulatory mechanism in health and disease...
  14. ncbi request reprint Methods to study the behavioral effects and expression of CB2 cannabinoid receptor and its gene transcripts in the chronic mild stress model of depression
    Emmanuel S Onaivi
    Department of Biology, William Paterson University, Wayne, NJ, USA
    Methods Mol Med 123:291-8. 2006
    ..These preliminary results, if confirmed, suggest that the CB2 receptors are expressed in the mammalian brain and may be involved in depression and substance abuse...
  15. ncbi request reprint Psychiatric disturbances regulate the innate immune system in CSF of conscious mice
    E S Onaivi
    Department of Biology, William Paterson University, Wayne, NJ, USA
    Transl Psychiatry 4:e367. 2014
    ....
  16. doi request reprint Cannabinoid receptors in brain: pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications
    Emmanuel S Onaivi
    Department of Biology, William Paterson University, Wayne, New Jersey 07470, USA
    Int Rev Neurobiol 88:335-69. 2009
    ..Thus, understanding the ECS in the human body and brain will contribute to elucidating this natural regulatory mechanism in health and disease...
  17. ncbi request reprint Cannabinoid CB2 receptors: immunohistochemical localization in rat brain
    Jian Ping Gong
    Molecular Neurobiology Branch, Intramural Research Program, National Institute on Drug Abuse, NIH, Baltimore, MD 20892, USA
    Brain Res 1071:10-23. 2006
    ..The multifocal expression of CB2 immunoreactivity in glial and neuronal patterns in a number of brain regions suggests reevaluation of the possible roles that CB2 receptors may play in the brain...
  18. ncbi request reprint Neuronal cytoskeleton and synaptic densities are altered after a chronic treatment with the cannabinoid receptor agonist WIN 55,212-2
    Patricia Tagliaferro
    Instituto de Biologia Celular y Neurociencias Prof E De Robertis, Facultad de Medicina, Universidad de Buenos Aires, Paraguay 2155, 3 er piso, C1121ABG, Buenos Aires, Argentina
    Brain Res 1085:163-76. 2006
    ....
  19. ncbi request reprint Behavioral methods in cannabinoid research
    Ester Fride
    Department of Behavioral Sciences, College of Judea and Samaria, Ariel, Israel
    Methods Mol Med 123:269-90. 2006
    ....
  20. ncbi request reprint Morphometric study on cytoskeletal components of neuronal and astroglial cells after chronic CB1 agonist treatment
    Patricia Tagliaferro
    Cellular Neurophysiology, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA
    Methods Mol Med 123:91-104. 2006
    ..However, changes in the expression of astroglial cytoskeletal proteins were not found...