Research Topics
| Ghada A SolimanSummaryAffiliation: Western Michigan University Country: USA Publications
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Detail Information
Publications
mTORC1 inhibition via rapamycin promotes triacylglycerol lipolysis and release of free fatty acids in 3T3-L1 adipocytesGhada A Soliman
Division of Metabolism, Endocrinology, and Diabetes, Department of Medicine, University of Michigan Medical School, 109 Zina Pitcher Place, Ann Arbor, MI 48109 2200, USA
Lipids 45:1089-100. 2010..Moreover, they reveal a novel metabolic function for mTORC1; mTORC1 signaling suppresses lipolysis, thus augmenting TAG storage...
Regulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylationKathryn G Foster
Department of Cell and Developmental Biology, Division of Metabolism, Endocrinology, and Diabetes, University of Michigan Medical School, Ann Arbor, Michigan 48109 2200, USA
J Biol Chem 285:80-94. 2010..Taken together, these data suggest that complex raptor phosphorylation functions as a biochemical rheostat that modulates mTORC1 signaling in accordance with environmental cues...
mTOR Ser-2481 autophosphorylation monitors mTORC-specific catalytic activity and clarifies rapamycin mechanism of actionGhada A Soliman
Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan 48109 2200, USA
J Biol Chem 285:7866-79. 2010....
Site-specific mTOR phosphorylation promotes mTORC1-mediated signaling and cell growthHugo A Acosta-Jaquez
Department of Cell and Developmental Biology, University of Michigan Medical School, 109 Zina Pitcher Place, Ann Arbor, MI 48109 2200, USA
Mol Cell Biol 29:4308-24. 2009....
