Bingyun Li

Summary

Affiliation: West Virginia University
Country: USA

Publications

  1. pmc Multilayer polypeptide nanoscale coatings incorporating IL-12 for the prevention of biomedical device-associated infections
    Bingyun Li
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV 26506 9196, USA
    Biomaterials 30:2552-8. 2009
  2. pmc Cefazolin embedded biodegradable polypeptide nanofilms promising for infection prevention: a preliminary study on cell responses
    Hongshuai Li
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia 26506 9196, USA
    J Orthop Res 28:992-9. 2010
  3. pmc Tunable drug loading and release from polypeptide multilayer nanofilms
    Bingbing Jiang
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV, USA
    Int J Nanomedicine 4:37-53. 2009
  4. pmc Nanomedicine as an emerging approach against intracellular pathogens
    Andrea L Armstead
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopedics, School of Medicine, West Virginia University, Morgantown, WV 26506 9196, USA
    Int J Nanomedicine 6:3281-93. 2011
  5. pmc Kaempferol nanoparticles achieve strong and selective inhibition of ovarian cancer cell viability
    Haitao Luo
    Department of Biology, Natural Science Division, Alderson Broaddus College, Philippi, WV 26416, USA
    Int J Nanomedicine 7:3951-9. 2012
  6. pmc Emerging ideas: Interleukin-12 nanocoatings prevent open fracture-associated infections
    Bingyun Li
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV 26506 9196, USA
    Clin Orthop Relat Res 469:3262-5. 2011
  7. doi request reprint Innovative nano-layered solid sorbents for CO2 capture
    Bingyun Li
    National Energy Technology Laboratory, U S Department of Energy, Morgantown, WV 26505, USA
    Chem Commun (Camb) 47:1719-21. 2011
  8. pmc Evaluation of local MCP-1 and IL-12 nanocoatings for infection prevention in open fractures
    Bingyun Li
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia 26506, USA
    J Orthop Res 28:48-54. 2010
  9. pmc Additive effects of exogenous IL-12 supplementation and antibiotic treatment in infection prophylaxis
    Brandon M Boyce
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia 26506, USA
    J Orthop Res 30:196-202. 2012
  10. pmc Interleukin 12 a key immunoregulatory cytokine in infection applications
    Therwa Hamza
    Department of Orthopaedics, West Virginia University, Morgantown, 26506, USA
    Int J Mol Sci 11:789-806. 2010

Collaborators

Detail Information

Publications17

  1. pmc Multilayer polypeptide nanoscale coatings incorporating IL-12 for the prevention of biomedical device-associated infections
    Bingyun Li
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV 26506 9196, USA
    Biomaterials 30:2552-8. 2009
    ..This approach could be a revolutionary step toward preventing device-associated infections using a non-antibiotic approach...
  2. pmc Cefazolin embedded biodegradable polypeptide nanofilms promising for infection prevention: a preliminary study on cell responses
    Hongshuai Li
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia 26506 9196, USA
    J Orthop Res 28:992-9. 2010
    ..aureus. These characteristics could be promising for preventing implant-associated infection and potentially improving bone healing...
  3. pmc Tunable drug loading and release from polypeptide multilayer nanofilms
    Bingbing Jiang
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV, USA
    Int J Nanomedicine 4:37-53. 2009
    ....
  4. pmc Nanomedicine as an emerging approach against intracellular pathogens
    Andrea L Armstead
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopedics, School of Medicine, West Virginia University, Morgantown, WV 26506 9196, USA
    Int J Nanomedicine 6:3281-93. 2011
    ..The characteristics of nanomedicine may prove advantageous in developing improved or alternative therapies for intracellular diseases...
  5. pmc Kaempferol nanoparticles achieve strong and selective inhibition of ovarian cancer cell viability
    Haitao Luo
    Department of Biology, Natural Science Division, Alderson Broaddus College, Philippi, WV 26416, USA
    Int J Nanomedicine 7:3951-9. 2012
    ..Both PEO-PPO-PEO and PLGA nanoparticle formulations had superior effects compared with kaempferol alone in reducing cancer cell viability...
  6. pmc Emerging ideas: Interleukin-12 nanocoatings prevent open fracture-associated infections
    Bingyun Li
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV 26506 9196, USA
    Clin Orthop Relat Res 469:3262-5. 2011
    ..Surgical trauma, burns, and major injuries such as traumatic open fractures induce immunosuppression, decrease resistance to infection, and decrease production of T helper type 1 (Th1) cytokines...
  7. doi request reprint Innovative nano-layered solid sorbents for CO2 capture
    Bingyun Li
    National Energy Technology Laboratory, U S Department of Energy, Morgantown, WV 26505, USA
    Chem Commun (Camb) 47:1719-21. 2011
    ..The developed sorbents had fast CO(2) adsorption and desorption properties and their CO(2) capture capacity increased with increasing nano-layers of the CO(2)-adsorbing polymer...
  8. pmc Evaluation of local MCP-1 and IL-12 nanocoatings for infection prevention in open fractures
    Bingyun Li
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia 26506, USA
    J Orthop Res 28:48-54. 2010
    ..aureus infection. No synergistic relationship in decreasing S. aureus infection was observed when MCP-1 and IL-12 p70 treatments were combined. This reported new approach may reduce antibiotic use and antibiotic resistance...
  9. pmc Additive effects of exogenous IL-12 supplementation and antibiotic treatment in infection prophylaxis
    Brandon M Boyce
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia 26506, USA
    J Orthop Res 30:196-202. 2012
    ..Therefore, exogenous IL-12, providing a mechanism of protection independent of antibiotic resistance, complements the routine use of antibiotics...
  10. pmc Interleukin 12 a key immunoregulatory cytokine in infection applications
    Therwa Hamza
    Department of Orthopaedics, West Virginia University, Morgantown, 26506, USA
    Int J Mol Sci 11:789-806. 2010
    ..This article describes the structure and biological activities of IL-12 in both the innate and adaptive arms of the immune system, and discusses the applications of IL-12 in treating and preventing infections...
  11. pmc Chaetoglobosin K inhibits tumor angiogenesis through downregulation of vascular epithelial growth factor-binding hypoxia-inducible factor 1α
    Haitao Luo
    Department of Biology, Natural Science Division, Alderson Broaddus College, Philippi, WV 26416, USA
    Anticancer Drugs 24:715-24. 2013
    ..Our data suggest that this natural fungal bioactive compound effectively inhibits angiogenesis through downregulation of VEGF-binding HIF-1α and could be an effective agent for cancer treatment. ..
  12. ncbi request reprint Polypeptide nanocoatings for preventing dental and orthopaedic device-associated infection: pH-induced antibiotic capture, release, and antibiotic efficacy
    Bingbing Jiang
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia, USA
    J Biomed Mater Res B Appl Biomater 88:332-8. 2009
    ....
  13. pmc Cationic antimicrobial peptide LL-37 is effective against both extra- and intracellular Staphylococcus aureus
    Jabeen Noore
    Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV, USA
    Antimicrob Agents Chemother 57:1283-90. 2013
    ..aureus than commonly used conventional antibiotics. LL-37 could potentially be used to treat chronic and recurrent infections due to its effectiveness in eliminating not only extracellular but also intracellular pathogens...
  14. pmc Unique antimicrobial effects of platelet-rich plasma and its efficacy as a prophylaxis to prevent implant-associated spinal infection
    Hongshuai Li
    Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV 26506, USA Department of Orthopaedics, University of Pittsburgh, Pittsburgh, Pennsylvania 15219, USA
    Adv Healthc Mater 2:1277-84. 2013
    ..e. 1, 2, and 3 weeks) and significant increase in mineralized tissues (thereby better bone healing) at postoperative weeks 2 and 3. PRP therefore may be a useful adjunct strategy against postoperative implant-associated infections. ..
  15. doi request reprint CO2 capture properties of lithium silicates with different ratios of Li2O/SiO2: an ab initio thermodynamic and experimental approach
    Yuhua Duan
    National Energy Technology Laboratory, United States Department of Energy, 236 Cochrans Mill Road, Pittsburgh, Pennsylvania 15236, USA
    Phys Chem Chem Phys 15:13538-58. 2013
    ..Based on our results, three mixing scenarios are discussed to provide general guidelines for designing new CO2 sorbents to fit practical needs. ..
  16. pmc Polypeptide multilayer film co-delivers oppositely-charged drug molecules in sustained manners
    Bingbing Jiang
    Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia 26506, United States
    Biomacromolecules 11:3630-7. 2010
    ....
  17. ncbi request reprint Exploring the potential role of tungsten carbide cobalt (WC-Co) nanoparticle internalization in observed toxicity toward lung epithelial cells in vitro
    Andrea L Armstead
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV 26506, USA Pharmaceutical and Pharmacological Sciences Graduate Program, School of Pharmacy, West Virginia University, Morgantown, WV 26506, USA
    Toxicol Appl Pharmacol 278:1-8. 2014
    ....