Bingyun Li

Summary

Affiliation: West Virginia University
Country: USA

Publications

  1. pmc Multilayer polypeptide nanoscale coatings incorporating IL-12 for the prevention of biomedical device-associated infections
    Bingyun Li
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV 26506 9196, USA
    Biomaterials 30:2552-8. 2009
  2. pmc Cefazolin embedded biodegradable polypeptide nanofilms promising for infection prevention: a preliminary study on cell responses
    Hongshuai Li
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia 26506 9196, USA
    J Orthop Res 28:992-9. 2010
  3. doi request reprint Innovative nano-layered solid sorbents for CO2 capture
    Bingyun Li
    National Energy Technology Laboratory, U S Department of Energy, Morgantown, WV 26505, USA
    Chem Commun (Camb) 47:1719-21. 2011
  4. doi request reprint Evaluation of local MCP-1 and IL-12 nanocoatings for infection prevention in open fractures
    Bingyun Li
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia 26506, USA
    J Orthop Res 28:48-54. 2010
  5. pmc Emerging ideas: Interleukin-12 nanocoatings prevent open fracture-associated infections
    Bingyun Li
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV 26506 9196, USA
    Clin Orthop Relat Res 469:3262-5. 2011
  6. ncbi request reprint Polypeptide nanocoatings for preventing dental and orthopaedic device-associated infection: pH-induced antibiotic capture, release, and antibiotic efficacy
    Bingbing Jiang
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia, USA
    J Biomed Mater Res B Appl Biomater 88:332-8. 2009
  7. pmc Additive effects of exogenous IL-12 supplementation and antibiotic treatment in infection prophylaxis
    Brandon M Boyce
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia 26506, USA
    J Orthop Res 30:196-202. 2012
  8. pmc Tunable drug loading and release from polypeptide multilayer nanofilms
    Bingbing Jiang
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV, USA
    Int J Nanomedicine 4:37-53. 2009
  9. pmc Interleukin 12 a key immunoregulatory cytokine in infection applications
    Therwa Hamza
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV 26506, USA E Mail T H
    Int J Mol Sci 11:789-806. 2010
  10. pmc Cationic antimicrobial peptide LL-37 is effective against both extra- and intracellular Staphylococcus aureus
    Jabeen Noore
    Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV, USA
    Antimicrob Agents Chemother 57:1283-90. 2013

Collaborators

  • Brock A Lindsey
  • Sanford E Emery
  • Bingbing Jiang
  • Hongshuai Li
  • Therwa Hamza
  • Jabeen Noore
  • Brandon M Boyce
  • John B Barnett
  • Adly Noore
  • Nina Clovis
  • John E Tidwell
  • David F Hubbard
  • Nina B Clovis
  • Gerald R Hobbs
  • E Suzanne Smith
  • Michael Hagar
  • Heather Ogle
  • Elizabeth Defusco

Detail Information

Publications12

  1. pmc Multilayer polypeptide nanoscale coatings incorporating IL-12 for the prevention of biomedical device-associated infections
    Bingyun Li
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV 26506 9196, USA
    Biomaterials 30:2552-8. 2009
    ..This approach could be a revolutionary step toward preventing device-associated infections using a non-antibiotic approach...
  2. pmc Cefazolin embedded biodegradable polypeptide nanofilms promising for infection prevention: a preliminary study on cell responses
    Hongshuai Li
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia 26506 9196, USA
    J Orthop Res 28:992-9. 2010
    ..aureus. These characteristics could be promising for preventing implant-associated infection and potentially improving bone healing...
  3. doi request reprint Innovative nano-layered solid sorbents for CO2 capture
    Bingyun Li
    National Energy Technology Laboratory, U S Department of Energy, Morgantown, WV 26505, USA
    Chem Commun (Camb) 47:1719-21. 2011
    ..The developed sorbents had fast CO(2) adsorption and desorption properties and their CO(2) capture capacity increased with increasing nano-layers of the CO(2)-adsorbing polymer...
  4. doi request reprint Evaluation of local MCP-1 and IL-12 nanocoatings for infection prevention in open fractures
    Bingyun Li
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia 26506, USA
    J Orthop Res 28:48-54. 2010
    ..aureus infection. No synergistic relationship in decreasing S. aureus infection was observed when MCP-1 and IL-12 p70 treatments were combined. This reported new approach may reduce antibiotic use and antibiotic resistance...
  5. pmc Emerging ideas: Interleukin-12 nanocoatings prevent open fracture-associated infections
    Bingyun Li
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV 26506 9196, USA
    Clin Orthop Relat Res 469:3262-5. 2011
    ..Surgical trauma, burns, and major injuries such as traumatic open fractures induce immunosuppression, decrease resistance to infection, and decrease production of T helper type 1 (Th1) cytokines...
  6. ncbi request reprint Polypeptide nanocoatings for preventing dental and orthopaedic device-associated infection: pH-induced antibiotic capture, release, and antibiotic efficacy
    Bingbing Jiang
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia, USA
    J Biomed Mater Res B Appl Biomater 88:332-8. 2009
    ....
  7. pmc Additive effects of exogenous IL-12 supplementation and antibiotic treatment in infection prophylaxis
    Brandon M Boyce
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia 26506, USA
    J Orthop Res 30:196-202. 2012
    ..Therefore, exogenous IL-12, providing a mechanism of protection independent of antibiotic resistance, complements the routine use of antibiotics...
  8. pmc Tunable drug loading and release from polypeptide multilayer nanofilms
    Bingbing Jiang
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV, USA
    Int J Nanomedicine 4:37-53. 2009
    ....
  9. pmc Interleukin 12 a key immunoregulatory cytokine in infection applications
    Therwa Hamza
    Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV 26506, USA E Mail T H
    Int J Mol Sci 11:789-806. 2010
    ..This article describes the structure and biological activities of IL-12 in both the innate and adaptive arms of the immune system, and discusses the applications of IL-12 in treating and preventing infections...
  10. pmc Cationic antimicrobial peptide LL-37 is effective against both extra- and intracellular Staphylococcus aureus
    Jabeen Noore
    Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV, USA
    Antimicrob Agents Chemother 57:1283-90. 2013
    ..aureus than commonly used conventional antibiotics. LL-37 could potentially be used to treat chronic and recurrent infections due to its effectiveness in eliminating not only extracellular but also intracellular pathogens...
  11. pmc Polypeptide multilayer film co-delivers oppositely-charged drug molecules in sustained manners
    Bingbing Jiang
    Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, West Virginia 26506, United States
    Biomacromolecules 11:3630-7. 2010
    ....
  12. pmc Unique antimicrobial effects of platelet-rich plasma and its efficacy as a prophylaxis to prevent implant-associated spinal infection
    Hongshuai Li
    Department of Orthopaedics, School of Medicine, West Virginia University, Morgantown, WV 26506, USA Department of Orthopaedics, University of Pittsburgh, Pittsburgh, Pennsylvania 15219, USA
    Adv Healthc Mater 2:1277-84. 2013
    ..e. 1, 2, and 3 weeks) and significant increase in mineralized tissues (thereby better bone healing) at postoperative weeks 2 and 3. PRP therefore may be a useful adjunct strategy against postoperative implant-associated infections. ..