Research Topics
Species
| F M CohanSummaryAffiliation: Wesleyan University Country: USA Publications
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Detail Information
Publications
Prokaryotic sex: eukaryote-like qualities of recombination in an Archaean lineageFrederick M Cohan
Department of Biology, Wesleyan University, Middletown, CT, USA
Curr Biol 22:R601-2. 2012..Genetic exchange within one Archaean lineage is a bit like sex in eukaryotes - cells fuse and huge segments of DNA are recombined - with consequences for the spread of adaptations across species...
Microbial genomics: E. coli relatives out of doors and out of bodyFrederick M Cohan
Department of Biology, Wesleyan University, Middletown, Connecticut, USA
Curr Biol 21:R587-9. 2011..coli have historically not shared environments with gut-associated E. coli...
Synthetic biology: now that we're creators, what should we create?Frederick M Cohan
Department of Biology, Wesleyan University, Middletown, Connecticut, USA
Curr Biol 20:R675-7. 2010..The technology allows the introduction of easily transferable adaptive units, as well as sets of genes that have likely never been transferred successfully...
Tracking bacterial responses to global warming with an ecotype-based systematicsF M Cohan
Department of Biology, Wesleyan University, Middletown, CT 06459 0170, USA
Clin Microbiol Infect 15:54-9. 2009..Creating an ecotype-based systematics will help to identify the units of diversity that we will want to track as we seek to observe the early microbial responses to global warming...
The origins of ecological diversity in prokaryotesFrederick M Cohan
Department of Biology, Wesleyan University, Middletown, CT 06459 0170, USA
Curr Biol 18:R1024-34. 2008..This effort will require development of universal approaches to hypothesize demarcations of ecotypes, and to confirm and characterize their ecological distinctness, without prior knowledge of a given clade's ecology...
Towards a conceptual and operational union of bacterial systematics, ecology, and evolutionFrederick M Cohan
Department of Biology, Wesleyan University, Middletown, CT 06459 0170, USA
Philos Trans R Soc Lond B Biol Sci 361:1985-96. 2006....
Sexual isolation and speciation in bacteriaFrederick M Cohan
Department of Biology, Wesleyan University, Middletown, CT 06459 0170, USA
Genetica 116:359-70. 2002..Interspecific recombination may also foster speciation by introducing novel gene loci from divergent species, allowing invasion of new niches...
Bacterial species and speciationF M Cohan
Department of Biology, Wesleyan University, Middletown, Connecticut 06459 0170, USA
Syst Biol 50:513-24. 2001..Owing to the rarity and promiscuity of bacterial genetic exchange, speciation in the bacterial world is expected to be much less constrained than in the world of animals and plants...
What are bacterial species?Frederick M Cohan
Department of Biology, Wesleyan University, Middletown, Connecticut 06459 0170, USA
Annu Rev Microbiol 56:457-87. 2002..These molecular methods suggest that a typical named species contains many ecotypes, each with the universal attributes of species. A named bacterial species is thus more like a genus than a species...
Barriers to genetic exchange between bacterial species: Streptococcus pneumoniae transformationJ Majewski
Department of Biology, Wesleyan University, Middletown, Connecticut 06459, USA
J Bacteriol 182:1016-23. 2000..We discuss the possible additional mechanisms of sexual isolation, in view of earlier findings from Bacillus, Escherichia, and Streptococcus...
A systematics for discovering the fundamental units of bacterial diversityFrederick M Cohan
Department of Biology, Wesleyan University, Middletown, Connecticut 06459 0170, USA
Curr Biol 17:R373-86. 2007..This would establish a theory-based species unit that holds the dynamic properties broadly attributed to species outside of microbiology...
Bacillus sonorensis sp. nov., a close relative of Bacillus licheniformis, isolated from soil in the Sonoran Desert, ArizonaM M Palmisano
Department of Biology, Wesleyan University, Middletown, CT 06459-0170, USA
Int J Syst Evol Microbiol 51:1671-9. 2001..B. sonorensis can be distinguished from B. licheniformis by salt tolerance, pigmentation, multilocus enzyme electrophoresis, reassociation of genomic DNA and sequence differences in protein-coding genes and 16S rRNA...
Ecology of speciation in the genus BacillusNora Connor
Department of Biology, Wesleyan University, Middletown, CT 06459, USA
Appl Environ Microbiol 76:1349-58. 2010..subtilis-B. licheniformis clade: ES and AdaptML identified several newly discovered clades as ecotypes that are distinct from any recognized taxon...
DNA sequence similarity requirements for interspecific recombination in BacillusJ Majewski
Department of Biology, Wesleyan University, Middletown, Connecticut 06459, USA
Genetics 153:1525-33. 1999..They also suggest a model for rapid spread of novel adaptations, such as antibiotic resistance genes, among related species...
Gradual evolution in bacteria: evidence from Bacillus systematicsMichael Feldgarden
Department of Biology, Wesleyan University, Middletown, CT 06459-0170, USA
Microbiology 149:3565-73. 2003..A protocol is presented for identifying those modifications of gene expression and those gene acquisitions that are most likely to have played a role in adaptive evolution...
Identifying the fundamental units of bacterial diversity: a paradigm shift to incorporate ecology into bacterial systematicsAlexander Koeppel
Departments of Biology and Mathematics and Computer Science, Wesleyan University, Middletown, CT 06459, USA
Proc Natl Acad Sci U S A 105:2504-9. 2008..Ecotype simulation provides a long-needed natural foundation for microbial ecology and systematics...
Population level functional diversity in a microbial community revealed by comparative genomic and metagenomic analysesDevaki Bhaya
Department of Plant Biology, Carnegie Institution, Stanford, CA 94305, USA
ISME J 1:703-13. 2007....
Cyanobacterial ecotypes in the microbial mat community of Mushroom Spring (Yellowstone National Park, Wyoming) as species-like units linking microbial community composition, structure and functionDavid M Ward
Department of Land Resources and Environmental Sciences, Montana State University, Bozeman, MT 59717, USA
Philos Trans R Soc Lond B Biol Sci 361:1997-2008. 2006..Further, we show that increased molecular resolution enhances our ability to detect ecotypes in this way, though yet higher molecular resolution is probably needed to detect all ecotypes in this microbial community...
Opinion: Re-evaluating prokaryotic speciesDirk Gevers
Laboratory of Microbiology and the Bioinformatics and Evolutionary Genomics Research Group, Ghent University VIB, Ghent, Belgium
Nat Rev Microbiol 3:733-9. 2005..We also consider the potential, and difficulties, of assigning species status to biologically or ecologically meaningful sequence clusters...
