B T Volpe

Summary

Affiliation: Weill Medical College of Cornell University
Country: USA

Publications

  1. ncbi request reprint Robotics and other devices in the treatment of patients recovering from stroke
    Bruce T Volpe
    Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, USA
    Curr Atheroscler Rep 6:314-9. 2004
  2. ncbi request reprint Robotics and other devices in the treatment of patients recovering from stroke
    Bruce T Volpe
    Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, USA
    Curr Neurol Neurosci Rep 5:465-70. 2005
  3. ncbi request reprint Is robot-aided sensorimotor training in stroke rehabilitation a realistic option?
    B T Volpe
    Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, USA
    Curr Opin Neurol 14:745-52. 2001
  4. ncbi request reprint Robotics in the rehabilitation treatment of patients with stroke
    Bruce T Volpe
    Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, USA
    Curr Atheroscler Rep 4:270-6. 2002
  5. ncbi request reprint A novel approach to stroke rehabilitation: robot-aided sensorimotor stimulation
    B T Volpe
    Department of Neurology and Neuroscience, Cornell University Medical College, Burke Institute of Medical Research, White Plains, NY 10605, USA
    Neurology 54:1938-44. 2000
  6. ncbi request reprint Neurotoxic APP C-terminal and beta-amyloid domains colocalize in the nuclei of substantia nigra pars reticulata neurons undergoing delayed degeneration
    L A DeGiorgio
    Department of Neurology and Neuroscience, Weill College of Medicine of Cornell University, The Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, USA
    Brain Res 874:137-46. 2000
  7. ncbi request reprint Robot-aided sensorimotor arm training improves outcome in patients with chronic stroke
    M Ferraro
    Department of Neurology and Neuroscience, Burke Institute of Medical Research, Weill Medical College, Cornell University, White Plains, NY 10605, USA
    Neurology 61:1604-7. 2003
  8. ncbi request reprint Temporal and sequential analysis of microglia in the substantia nigra following medial forebrain bundle axotomy in rat
    S Sugama
    Laboratory of Molecular Neurobiology, The W M Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, USA
    Neuroscience 116:925-33. 2003
  9. ncbi request reprint Differentiation of the dopaminergic phenotype in the olfactory system of neonatal and adult mice
    Sachiko Saino-Saito
    Weill Medical College, Cornell University at The Burke Medical Research Institute, White Plains, New York 10605, USA
    J Comp Neurol 479:389-98. 2004
  10. ncbi request reprint CD40-CD40L interactions promote neuronal death in a model of neurodegeneration due to mild impairment of oxidative metabolism
    Zun Ji Ke
    Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, NY, USA
    Neurochem Int 47:204-15. 2005

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Robotics and other devices in the treatment of patients recovering from stroke
    Bruce T Volpe
    Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, USA
    Curr Atheroscler Rep 6:314-9. 2004
    ..These data from robotic trials continue to contribute to the emerging scientific basis of neuro-rehabilitation...
  2. ncbi request reprint Robotics and other devices in the treatment of patients recovering from stroke
    Bruce T Volpe
    Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, USA
    Curr Neurol Neurosci Rep 5:465-70. 2005
    ..These data from robotic trials continue to contribute to the emerging scientific basis of neuro-rehabilitation...
  3. ncbi request reprint Is robot-aided sensorimotor training in stroke rehabilitation a realistic option?
    B T Volpe
    Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, USA
    Curr Opin Neurol 14:745-52. 2001
    ....
  4. ncbi request reprint Robotics in the rehabilitation treatment of patients with stroke
    Bruce T Volpe
    Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, USA
    Curr Atheroscler Rep 4:270-6. 2002
    ..With these new tools, therapists will measure aspects of outcome objectively and contribute to the emerging scientific basis of neuro-rehabilitation...
  5. ncbi request reprint A novel approach to stroke rehabilitation: robot-aided sensorimotor stimulation
    B T Volpe
    Department of Neurology and Neuroscience, Cornell University Medical College, Burke Institute of Medical Research, White Plains, NY 10605, USA
    Neurology 54:1938-44. 2000
    ..In patients with stroke, the authors tested whether additional sensorimotor training of the paralyzed or paretic upper limb delivered by a robotic device enhanced motor outcome...
  6. ncbi request reprint Neurotoxic APP C-terminal and beta-amyloid domains colocalize in the nuclei of substantia nigra pars reticulata neurons undergoing delayed degeneration
    L A DeGiorgio
    Department of Neurology and Neuroscience, Weill College of Medicine of Cornell University, The Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, USA
    Brain Res 874:137-46. 2000
    ..These findings suggest that intranuclear APP C-terminal fragment may play a role in genomic events contributing to delayed neuron degeneration in the SNpR...
  7. ncbi request reprint Robot-aided sensorimotor arm training improves outcome in patients with chronic stroke
    M Ferraro
    Department of Neurology and Neuroscience, Burke Institute of Medical Research, Weill Medical College, Cornell University, White Plains, NY 10605, USA
    Neurology 61:1604-7. 2003
    ..Task-specific motor training attenuated a chronic neurologic deficit well beyond the expected period for improvement after stroke...
  8. ncbi request reprint Temporal and sequential analysis of microglia in the substantia nigra following medial forebrain bundle axotomy in rat
    S Sugama
    Laboratory of Molecular Neurobiology, The W M Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, USA
    Neuroscience 116:925-33. 2003
    ....
  9. ncbi request reprint Differentiation of the dopaminergic phenotype in the olfactory system of neonatal and adult mice
    Sachiko Saino-Saito
    Weill Medical College, Cornell University at The Burke Medical Research Institute, White Plains, New York 10605, USA
    J Comp Neurol 479:389-98. 2004
    ....
  10. ncbi request reprint CD40-CD40L interactions promote neuronal death in a model of neurodegeneration due to mild impairment of oxidative metabolism
    Zun Ji Ke
    Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, NY, USA
    Neurochem Int 47:204-15. 2005
    ..The results indicate that CD40-CD40L interactions promote neuronal death in early stages of TD, but that at later phases the protective effects of the diminished CD40 or CD40L are over-ridden by other mechanisms...
  11. ncbi request reprint CD40L deletion delays neuronal death in a model of neurodegeneration due to mild impairment of oxidative metabolism
    Zun Ji Ke
    Institute for Nutritional Sciences, SIBS, CAS, 294 Taiyuan Road, Shanghai 200031, PR China
    J Neuroimmunol 164:85-92. 2005
    ..The current results suggest that CD40L-mediated immune and inflammatory responses have a role in TD-induced neuronal death...
  12. ncbi request reprint 17 beta-estradiol treatment retards excitotoxic delayed degeneration in substantia nigra reticulata neurons
    Lorraine A DeGiorgio
    Burke Medical Research Institute, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, 785 Mamaroneck Avenue, White Plains, NY 10605, USA
    Brain Res 936:15-20. 2002
    ..Physiologic levels of estrogen delivered days after the excitotoxic stress completely protected neurons in the substantia nigra reticulata 6 days post lesion and slowed degeneration 8 days post lesion...
  13. ncbi request reprint Continuous passive motion improves shoulder joint integrity following stroke
    Daniel Lynch
    Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, USA
    Clin Rehabil 19:594-9. 2005
    ....
  14. pmc Customized interactive robotic treatment for stroke: EMG-triggered therapy
    Laura Dipietro
    Newman Laboratory for Biomechanics and Human Rehabilitation, Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    IEEE Trans Neural Syst Rehabil Eng 13:325-34. 2005
    ..Preliminary experiments aimed at testing the proposed system and gaining insight into the potential of EMG-triggered, robot-assisted therapy are reported...
  15. pmc Stochastic estimation of arm mechanical impedance during robotic stroke rehabilitation
    Jerome J Palazzolo
    Massachusetts Institute of Technology, Department of Mechanical Engineering, Newman Laboratory for Biomechanics and Human Rehabilitation, Cambridge, MA 02139, USA
    IEEE Trans Neural Syst Rehabil Eng 15:94-103. 2007
    ..Data was analyzed by spectral procedures that make no assumption about model structure. The method was validated by measuring simple mechanical hardware and results from a patient's hemiplegic arm are presented...
  16. pmc Robot-aided neurorehabilitation: a robot for wrist rehabilitation
    Hermano Igo Krebs
    Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    IEEE Trans Neural Syst Rehabil Eng 15:327-35. 2007
    ..Here, we report on the initial results on 36 of these volunteers. These results demonstrate that further improvement should be expected by adding additional training to other limb segments...
  17. doi request reprint Intensive sensorimotor arm training mediated by therapist or robot improves hemiparesis in patients with chronic stroke
    Bruce T Volpe
    Department of Neurology and Neuroscience, Burke Institute of Medical Research, Weill Medical College, Cornell University, White Plains, NY, USA
    Neurorehabil Neural Repair 22:305-10. 2008
    ..These new protocols, rendered by either therapist or robot, can be standardized, tested, and replicated, and potentially will contribute to rational activity-based programs...
  18. ncbi request reprint Does shorter rehabilitation limit potential recovery poststroke?
    Susan E Fasoli
    Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Neurorehabil Neural Repair 18:88-94. 2004
    ....
  19. ncbi request reprint Marked dopaminergic cell loss subsequent to developmental, intranigral expression of glial cell line-derived neurotrophic factor
    Hong S Chun
    Department of Neurology and Neuroscience, Weill Medical College of Cornell University at the W M Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, New York 10605, USA
    Exp Neurol 173:235-44. 2002
    ..Further elucidation of the mechanisms underlying differential GDNF actions will greatly improve the pharmacological efficacy of GDNF in fetal neural transplantation as well as adult neuronal gene therapy in PD patients...
  20. ncbi request reprint Cross-linking cellular prion protein triggers neuronal apoptosis in vivo
    Laura Solforosi
    Department of Immunology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Science 303:1514-6. 2004
    ..These findings suggest that PrPC functions in the control of neuronal survival and provides a model to explore whether cross-linking of PrPC by oligomeric PrPSc can promote neuronal loss during prion infection...
  21. ncbi request reprint Amyloid precursor protein gene disruption attenuates degeneration of substantia nigra compacta neurons following axotomy
    Lorraine A DeGiorgio
    Burke Medical Research Institute, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, 785 Mamaroneck Avenue, White Plains, NY 10605, USA
    Brain Res 938:38-44. 2002
    ..These data showed that a novel nuclear C-terminal fragment appeared coincident with SNc neuron degeneration, and that APP deficiency correlated with significant neuroprotection in vivo...
  22. ncbi request reprint Microglial phagocytosis of dopamine neurons at early phases of apoptosis
    Byung Pil Cho
    The Burke Medical Research Institute, Department of Neurology and Neuroscience, Weill Medical College, Graduate School of Medical Sciences of Cornell University, White Plains, New York 10605, USA
    Cell Mol Neurobiol 23:551-60. 2003
    ..Alternatively, interventions that suppress early activation of microglia might lead to novel mechanisms for neuron protection...
  23. ncbi request reprint Robot-aided sensorimotor training in stroke rehabilitation
    Bruce T Volpe
    Burke Medical Research Institute, White Plains, New York, USA
    Adv Neurol 92:429-33. 2003
    ..Therapists equipped with a robotic device can increase the amount and intensity of movement of the paralyzed limb without sacrificing time spent training complex functionally appropriate kinematics...
  24. ncbi request reprint Reversal of thiamine deficiency-induced neurodegeneration
    Zun Ji Ke
    Department of Neurology and Neuroscience, Weill Medical College of Cornell University at Burke Medical Research Institute, White Plains, New York, USA
    J Neuropathol Exp Neurol 62:195-207. 2003
    ..endothelial cells, and microglia contemporaneously. This model provides a unique paradigm for elucidating the molecular mechanisms involved in neuronal commitment to neuronal death cascades and contributory microglial activity...
  25. ncbi request reprint Age-related microglial activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurodegeneration in C57BL/6 mice
    Shuei Sugama
    Harold L Dorris Neurological Research Center, Department of Neuropharmacology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Brain Res 964:288-94. 2003
    ..The present study suggests that age-related microglial activation in the SN may be relevant to the higher susceptibility to MPTP neurotoxicity in older mice...
  26. ncbi request reprint APP knockout attenuates microglial activation and enhances neuron survival in substantia nigra compacta after axotomy
    Lorraine A DeGiorgio
    Burke Medical Research Institute, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, White Plains, New York 10605, USA
    Glia 38:174-8. 2002
    ..The delayed and limited local microglial activation and increased neuron survival in response to distal axotomy of SNc neurons in APP KO mice are consistent with the important role APP in neuronal stress responses in vivo...
  27. pmc Human lupus autoantibodies against NMDA receptors mediate cognitive impairment
    Czeslawa Kowal
    Department of Medicine, Columbia University Medical Center, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 103:19854-9. 2006
    ..Which aspects of neuropsychiatric lupus may be mediated by anti-NMDAR Abs, how often, and in which patients are now important clinical questions...
  28. ncbi request reprint Motions or muscles? Some behavioral factors underlying robotic assistance of motor recovery
    Neville Hogan
    Newman Laboratory, Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    J Rehabil Res Dev 43:605-18. 2006
    ..Together these results indicate that movement coordination rather than muscle activation may be the most appropriate focus for robotic therapy...
  29. pmc Immunity and behavior: antibodies alter emotion
    Patricio T Huerta
    Burke Medical Research Institute, White Plains, NY 10605, USA
    Proc Natl Acad Sci U S A 103:678-83. 2006
    ..Thus, the agent used to open the BBB determines which brain region is made vulnerable to neurotoxic Abs, and Abs that penetrate brain tissue can cause changes not only in cognitive competence, but also in emotional behavior...
  30. ncbi request reprint Assessing the motor status score: a scale for the evaluation of upper limb motor outcomes in patients after stroke
    Mark Ferraro
    Burke Medical Research Institute, Burke Rehabilitation Hospital, White Plains, NY, USA
    Neurorehabil Neural Repair 16:283-9. 2002
    ..98, P < 0.0001). Finally the correlation between the MSS and the FM (R2 = 0.964) was significant (P < 0.0001). The MSS affords a reliable and valid assessment of upper limb impairment and disability following stroke...
  31. ncbi request reprint "Stroke, stroke": a coxswain's call for more work and more innovation
    Bruce T Volpe
    J Rehabil Res Dev 41:vii-x. 2004
  32. ncbi request reprint Cognition and immunity; antibody impairs memory
    Czeslawa Kowal
    Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Immunity 21:179-88. 2004
    ..Furthermore, NMDA receptor antagonists prevent antibody-mediated damage and may constitute a new approach to therapy in SLE...