Youming Xie

Summary

Affiliation: Wayne State University
Country: USA

Publications

  1. doi request reprint Feedback regulation of proteasome gene expression and its implications in cancer therapy
    Youming Xie
    Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, 110 E Warren Ave, Detroit, MI 48201, USA
    Cancer Metastasis Rev 29:687-93. 2010
  2. doi request reprint Structure, assembly and homeostatic regulation of the 26S proteasome
    Youming Xie
    Barbara Ann Karmanos Cancer Institute, Department of Oncology, Wayne State University School of Medicine, 110 E Warren Ave, Detroit, MI 48201, USA
    J Mol Cell Biol 2:308-17. 2010
  3. doi request reprint The CCAAT box-binding transcription factor NF-Y regulates basal expression of human proteasome genes
    Haiming Xu
    Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Biochim Biophys Acta 1823:818-25. 2012
  4. pmc Pharmacologic ER stress induces non-alcoholic steatohepatitis in an animal model
    Jin Sook Lee
    Center for Molecular Medicine and Genetics, the Wayne State University School of Medicine, Detroit, MI 48201, USA
    Toxicol Lett 211:29-38. 2012

Collaborators

  • Kezhong Zhang
  • Li Li
  • Jin Sook Lee
  • Haiming Xu
  • Seung Wook Ha
  • Jianpu Zheng
  • Roberto Mendez
  • Jiejun Fu
  • Ze Zheng
  • Donghong Ju

Detail Information

Publications4

  1. doi request reprint Feedback regulation of proteasome gene expression and its implications in cancer therapy
    Youming Xie
    Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, 110 E Warren Ave, Detroit, MI 48201, USA
    Cancer Metastasis Rev 29:687-93. 2010
    ..This finding also has important implications in cancer therapy that uses small molecule inhibitors to target the proteasome...
  2. doi request reprint Structure, assembly and homeostatic regulation of the 26S proteasome
    Youming Xie
    Barbara Ann Karmanos Cancer Institute, Department of Oncology, Wayne State University School of Medicine, 110 E Warren Ave, Detroit, MI 48201, USA
    J Mol Cell Biol 2:308-17. 2010
    ..The implications of these new developments in cancer therapy will also be discussed...
  3. doi request reprint The CCAAT box-binding transcription factor NF-Y regulates basal expression of human proteasome genes
    Haiming Xu
    Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Biochim Biophys Acta 1823:818-25. 2012
    ..This study unveils a new role for NF-Y in the regulation of human proteasome genes and suggests that NF-Y may be a potential target for cancer therapy...
  4. pmc Pharmacologic ER stress induces non-alcoholic steatohepatitis in an animal model
    Jin Sook Lee
    Center for Molecular Medicine and Genetics, the Wayne State University School of Medicine, Detroit, MI 48201, USA
    Toxicol Lett 211:29-38. 2012
    ..Our study not only confirmed that pharmacologic ER stress is a strong "hit" that triggers NASH, but also demonstrated crucial molecular links between ER stress, lipid metabolism, and inflammation in the liver in vivo...