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Genomes and Genes | Derek E WildmanSummaryAffiliation: Wayne State University Country: USA Publications
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Publications
A map of the common chimpanzee genomeDerek E Wildman
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, 540 E Canfield Ave, Detroit, MI 48201, USA
Bioessays 24:490-3. 2002..77%) between humans and chimpanzees, while highlighting intriguing areas of potential difference. If we wish to understand the genetic basis of humankind, the completion of the chimpanzee genome deserves high priority...- Mitochondrial evidence for the origin of hamadryas baboonsDerek E Wildman
Department of Anthropology, New York Univesity, USA
Mol Phylogenet Evol 32:287-96. 2004..The mitochondrial paraphyly of Ethiopian hamadryas and anubis (P. anubis) baboons suggests an extensive and complex history of sex-specific introgression... 
Emergence of hormonal and redox regulation of galectin-1 in placental mammals: implication in maternal-fetal immune toleranceNandor Gabor Than
Perinatology Research Branch, National Institute of Child Health and Human Development, National Institutes of Health, and Department of Health and Human Services, Detroit, MI 48201, USA
Proc Natl Acad Sci U S A 105:15819-24. 2008....- Elephant transcriptome provides insights into the evolution of eutherian placentationZhuo Cheng Hou
Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development NIH DHHS, Detroit, Michigan, USA
Genome Biol Evol 4:713-25. 2012.... - Phylogenomic analyses reveal convergent patterns of adaptive evolution in elephant and human ancestriesMorris Goodman
Center for Molecular Medicine and Genetics, Department of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, MI 48201, USA
Proc Natl Acad Sci U S A 106:20824-9. 2009.... - The human progesterone receptor shows evidence of adaptive evolution associated with its ability to act as a transcription factorCaoyi Chen
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, USA
Mol Phylogenet Evol 47:637-49. 2008..Positive selection provides the basis for the hypothesis that changes in structure and function of the progesterone receptor during evolution contribute to the diversity of primate reproductive biology, especially in parturition... - Ancient origin of placental expression in the growth hormone genes of anthropoid primatesZack Papper
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, USA
Proc Natl Acad Sci U S A 106:17083-8. 2009..e., the roles played by placenta-expressed GHs in human pregnancy may have a longer evolutionary history than previously appreciated)... - Silencing, positive selection and parallel evolution: busy history of primate cytochromes CDenis Pierron
Center for Molecular Medicine and Genetics, Wayne State University, School of Medicine, Detroit, Michigan, United States of America
PLoS ONE 6:e26269. 2011.... - Molecular evolution of the cytochrome c oxidase subunit 5A gene in primatesMonica Uddin
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit MI 48201, USA
BMC Evol Biol 8:8. 2008..Here, we test the hypothesis that COX5A, the ETC gene that encodes cytochrome c oxidase subunit 5A, shows a pattern of anthropoid-specific adaptive evolution, and investigate the distribution of this protein in catarrhine brains... - Sister grouping of chimpanzees and humans as revealed by genome-wide phylogenetic analysis of brain gene expression profilesMonica Uddin
Center for Molecular Medicine and Genetics, Department of Anatomy and Cell Biology, Wayne State University School of Medicine, 540 East Canfield Avenue, Detroit, MI 48201, USA
Proc Natl Acad Sci U S A 101:2957-62. 2004.... 
Genomic data reject the hypothesis of a prosimian primate cladeNatalie M Jameson
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, USA
J Hum Evol 61:295-305. 2011..Our results provide the framework on which primate morphological, reproductive, and genomic features can be reconstructed in the broader context of mammalian phylogeny...- Dynamic gene expression in the human cerebral cortex distinguishes children from adultsKirstin N Sterner
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, Michigan, United States of America
PLoS ONE 7:e37714. 2012.... - Rapid nonsynonymous evolution of the iron-sulfur protein in anthropoid primatesJeffrey W Doan
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, 540 E Canfield Avenue, Detroit, MI 48201, USA
J Bioenerg Biomembr 37:35-41. 2005..Nevertheless, we find that the catalytically active ISP has an accelerated rate of amino acid replacement in anthropoid primates whereas the catalytically inactive subunit 9 does not... - Distinct genomic signatures of adaptation in pre- and postnatal environments during human evolutionMonica Uddin
Center for Molecular Medicine and Genetics and Department of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, MI 48201, USA
Proc Natl Acad Sci U S A 105:3215-20. 2008..Comparing adaptively evolving genes from pre- and postnatal-stage tissues suggests that different selective pressures act on the development vs. the maintenance of the human phenotype... - Coadaptive evolution in cytochrome c oxidase: 9 of 13 subunits show accelerated rates of nonsynonymous substitution in anthropoid primatesJeffrey W Doan
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, USA
Mol Phylogenet Evol 33:944-50. 2004 - Chorioamnionitis and increased galectin-1 expression in PPROM --an anti-inflammatory response in the fetal membranes?Nandor Gabor Than
Perinatology Research Branch, NICHD NIH DHHS, Wayne State University Hutzel Women s Hospital, 3990 John R, Box 4, Detroit, MI 48201, USA
Am J Reprod Immunol 60:298-311. 2008..Galectin-1 can regulate immune responses upon infection and inflammation. We determined galectin-1 expression in the chorioamniotic membranes and its changes during histological chorioamnionitis... - Inhibitory interneurons of the human prefrontal cortex display conserved evolution of the phenotype and related genesChet C Sherwood
Department of Anthropology, The George Washington University, Washington, DC 20052, USA
Proc Biol Sci 277:1011-20. 2010..Thus, it is likely that other significant modifications to the connectivity and molecular biology of the prefrontal cortex were overlaid on this conserved interneuron architecture in the course of human evolution... - Adaptive history of single copy genes highly expressed in the term human placentaZhuocheng Hou
Perinatology Research Branch, NICHD NIH DHHS Wayne State University, Detroit, MI 48201, USA
Genomics 93:33-41. 2009..Adaptations in genes highly expressed in human placenta are attractive candidates for functional and clinical studies... - Rapid electrostatic evolution at the binding site for cytochrome c on cytochrome c oxidase in anthropoid primatesTimothy R Schmidt
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, USA
Proc Natl Acad Sci U S A 102:6379-84. 2005..We suggest that reducing the electrostatic interaction between COX and CYC was part of the adaptive evolution underlying the emergence of anthropoid primates... - Phylogenetic comparisons suggest that distance from the locus control region guides developmental expression of primate beta-type globin genesRobert M Johnson
Department of Biochemistry and Molecular Biology, Wayne State University School of Medicine, Detroit, MI 48201, USA
Proc Natl Acad Sci U S A 103:3186-91. 2006.... - Evolution of the couple cytochrome c and cytochrome c oxidase in primatesDenis Pierron
Wayne State University School of Medicine, Detroit, MI 48201, USA
Adv Exp Med Biol 748:185-213. 2012..Finally, we discuss and review the co-occurring primate phenotypic evolution... - Moving primate genomics beyond the chimpanzee genomeMorris Goodman
Department of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
Trends Genet 21:511-7. 2005..Some of these traits have been discovered recently, particularly in genes encoding proteins that are important for brain function... - Phylogeny of the Ferungulata (Mammalia: Laurasiatheria) as determined from phylogenomic dataZhuo Cheng Hou
Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development NIH DHHS, Detroit, MI 48201, USA
Mol Phylogenet Evol 52:660-4. 2009.... - Dolphin genome provides evidence for adaptive evolution of nervous system genes and a molecular rate slowdownMichael R McGowen
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48210, USA
Proc Biol Sci 279:3643-51. 2012..This study underlines the parallel molecular trajectory of cetaceans with other mammalian groups possessing large brains... - Cytochrome c oxidase: evolution of control via nuclear subunit additionDenis Pierron
Wayne State University School of Medicine, Detroit, MI, USA
Biochim Biophys Acta 1817:590-7. 2012.... - Accelerated evolution of the electron transport chain in anthropoid primatesLawrence I Grossman
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, 540 East Canfield Avenue, Detroit, MI 48201, USA
Trends Genet 20:578-85. 2004..Two important questions are: (i) how has evolution altered ETC function? and; (ii) how might functional changes in the ETC be linked to evolution of an expanded neocortical brain?.. - Implications of natural selection in shaping 99.4% nonsynonymous DNA identity between humans and chimpanzees: enlarging genus HomoDerek E Wildman
Center for Molecular Medicine and Genetics and Department of Anatomy and Cell Biology, Wayne State University School of Medicine, 540 East Canfield Avenue, Detroit, MI 48201, USA
Proc Natl Acad Sci U S A 100:7181-8. 2003.... 
OCPAT: an online codon-preserved alignment tool for evolutionary genomic analysis of protein coding sequencesGuozhen Liu
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine Detroit, MI 48201, USA
Source Code Biol Med 2:5. 2007..Since this feature is not available in most alignment tools, codon reading frames often must be checked manually before evolutionary analyses can commence...- A fully resolved genus level phylogeny of neotropical primates (Platyrrhini)Derek E Wildman
Center for Molecular Medicine and Genetics, Wayne State University, School of Medicine, 540 E Canfield Ave, Detroit, MI 48201, USA
Mol Phylogenet Evol 53:694-702. 2009..With a fully resolved platyrrhine phylogeny in place it is now possible to design and test hypotheses regarding the evolution and diversification of platyrrhine phenotypes and life histories... - Spontaneous abortion and preterm labor and delivery in nonhuman primates: evidence from a captive colony of chimpanzees (Pan troglodytes)Derek E Wildman
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, Michigan, United States of America
PLoS ONE 6:e24509. 2011..Preterm birth is a leading cause of perinatal mortality, yet the evolutionary history of this obstetrical syndrome is largely unknown in nonhuman primate species... - The phylogenetic history of New World monkey beta globin reveals a platyrrhine beta to delta gene conversion in the atelid ancestryTom Prychitko
Department of Anatomy and Cell Biology, Wayne State University, Detroit, MI, USA
Mol Phylogenet Evol 35:225-34. 2005..This phylogeny generally agreed with results from other nuclear genes. The one exception was that the beta sequences did not place the callitrichine clade within the Cebidae but weakly joined the callitrichine and atelid clades... - Evolution of increased glia-neuron ratios in the human frontal cortexChet C Sherwood
Department of Anthropology, The George Washington University, Washington, DC 20052, USA
Proc Natl Acad Sci U S A 103:13606-11. 2006.... - A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell deathNandor Gabor Than
Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Detroit, MI 48201, USA
Proc Natl Acad Sci U S A 106:9731-6. 2009.... - Phylogenetic relationships and divergence times among New World monkeys (Platyrrhini, Primates)Juan C Opazo
Center for Molecular Medicine and Genetics, School of Medicine, Wayne State University, Detroit, MI 48201, USA
Mol Phylogenet Evol 40:274-80. 2006..Divergence time estimations using both local molecular clock and Bayesian approaches suggest the families diverged from one another over a short period of geological time in the late Oligocene-early Miocene... - Prolonged myelination in human neocortical evolutionDaniel J Miller
Department of Anthropology, The George Washington University, Washington, DC 20052, USA
Proc Natl Acad Sci U S A 109:16480-5. 2012..Thus, these species differences suggest that the human-specific shift in the timing of cortical maturation during adolescence may have implications for vulnerability to certain psychiatric disorders... - Adrenal androgen production in catarrhine primates and the evolution of adrenarcheRobin M Bernstein
Department of Anthropology, Center for the Advanced Study of Hominid Paleobiology, George Washington University, Washington, DC 20052, USA
Am J Phys Anthropol 147:389-400. 2012..Taken together, our findings suggest that while adrenarche has been suggested to be unique to hominoids, the evolutionary roots for this developmental stage are more ancient... - Genomics, biogeography, and the diversification of placental mammalsDerek E Wildman
Perinatology Research Branch, National Institute of Child Health and Human Development National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Proc Natl Acad Sci U S A 104:14395-400. 2007..Crown placental mammalian diversification appears to be largely the result of ancient plate tectonic events that allowed time for convergent phenotypes to evolve in the descendant clades... - Development and annotation of shotgun sequence libraries from New World monkeysNatalie M Jameson
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, 540 East Canfield, Detroit, MI 48021, USA
Mol Ecol Resour 12:950-5. 2012..Thus, they are likely to be highly informative for inferring neutral evolutionary patterns and genomic evolution for other New World monkeys... - Galectins: guardians of eutherian pregnancy at the maternal-fetal interfaceNandor Gabor Than
Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD, National Institutes of Health NIH, Department of Health and Human Services DHHS, Detroit, MI, USA
Trends Endocrinol Metab 23:23-31. 2012.... - Severe preeclampsia is characterized by increased placental expression of galectin-1Nandor Gabor Than
Perinatology Research Branch, NICHD, NIH, DHHS, Detroit, Michigan 48201, USA
J Matern Fetal Neonatal Med 21:429-42. 2008..To test this hypothesis, we studied placental galectin-1 mRNA and protein expression and localization in women with preeclampsia (PE) and in those who delivered a small-for-gestational age (SGA) neonate... - Adaptive evolution of cytochrome c oxidase subunit VIII in anthropoid primatesAllon Goldberg
Center for Molecular Medicine and Genetics and Department of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, MI 48201, USA
Proc Natl Acad Sci U S A 100:5873-8. 2003..We argue that these changes were linked to the evolution of an expanded neocortex in anthropoid primates... - New Onto-Tools: Promoter-Express, nsSNPCounter and Onto-TranslatePurvesh Khatri
Department of Computer Science, Wayne State University, 431 State Hall, Detroit, MI 48202, USA
Nucleic Acids Res 34:W626-31. 2006..Currently, Onto-Translate allows arbitrary mappings between 28 types of IDs for 53 organisms. Onto-Tools are freely available at http://vortex.cs.wayne.edu/Projects.html... - Episodic positive selection in ape cytochrome c oxidase subunit IVDerek E Wildman
Mol Biol Evol 19:1812-5. 2002 - Evolution of the mammalian placenta revealed by phylogenetic analysisDerek E Wildman
Perinatology Research Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
Proc Natl Acad Sci U S A 103:3203-8. 2006..The influence of these factors on placental development needs further investigation... - Over-expression of the thrombin receptor (PAR-1) in the placenta in preeclampsia: a mechanism for the intersection of coagulation and inflammationOffer Erez
Perinatology Research Branch, NICHD, NIH, DHHS, Bethesda, Maryland, USA
J Matern Fetal Neonatal Med 21:345-55. 2008..The aim of this study was to determine whether preterm PE is associated with changes in placental expression of PAR-1... - Functionally important glycosyltransferase gain and loss during catarrhine primate emergenceChihiro Koike
Department of Surgery and Thomas E Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Proc Natl Acad Sci U S A 104:559-64. 2007..However, we emphasize that positively selected regulatory changes in sugar chain metabolism might well have contributed in a major way to catarrhine origins... - Relationship between maternal and fetal plasma glucose and insulin concentrations during graded maternal hyperglycemic states in primatesJoaquin Santolaya-Forgas
Perinatology Research Branch, NICHD NIH DHHS, Bethesda, Maryland 20892, USA
Am J Perinatol 23:369-75. 2006....