Research Topics
Genomes and GenesSpecies | N Volkan AdsaySummaryAffiliation: Wayne State University Country: USA Publications
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Publications
Pancreatic tumors with cystic dilatation of the ducts: intraductal papillary mucinous neoplasms and intraductal oncocytic papillary neoplasmsN V Adsay
Department of Pathology, The Karmanos Cancer Institute, Harper Hospital, Wayne State University School of Medicine, Detroit, MI 48201, USA
Semin Diagn Pathol 17:16-30. 2000..Therefore, IPMNs and IOPNs should be examined carefully and sampled extensively, first, to confirm that the main pathology is an intraductal process and, more importantly, to rule out the presence of an invasive carcinoma...- Cystic lesions of the pancreasN Volkan Adsay
Department of Pathology, Harper Hospital and Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA
Mod Pathol 20:S71-93. 2007..Thus, significant developments have taken place in the classification and our understanding of pancreatic cystic tumors in the past few years, and experience with these lesions is likely to grow exponentially in the coming years... - Intraductal and papillary variants of acinar cell carcinomas: a new addition to the challenging differential diagnosis of intraductal neoplasmsOlca Basturk
Department of Pathology, Wayne State University and Karmanos Cancer Institute, Detroit, MI 48201, USA
Am J Surg Pathol 31:363-70. 2007..The clinical significance of this variant is difficult to determine; however, it appears that the tumors are relatively small and metastasis at presentation is less common than typically seen in ACCs (1/7 vs. 50%)... - Diagnostic features and differential diagnosis of autoimmune pancreatitisN Volkan Adsay
Department of Pathology, The Karmanos Cancer Institute and Wayne State University School of Medicine, Detroit, Michigan, USA
Semin Diagn Pathol 22:309-17. 2005..It is important to recognize the distinctive clinicopathologic features of this entity, so that it can be diagnosed accurately and managed appropriately... - Chronic pancreatitis or pancreatic ductal adenocarcinoma?N Volkan Adsay
Department of Pathology, The Karmanos Cancer Institute and Wayne State University School of Medicine, Detroit, Michigan, USA
Semin Diagn Pathol 21:268-76. 2004..Combinations of these criteria should aid in the differential diagnosis of invasive ductal adenocarcinoma from benign/reactive ducts in the pancreas... - Pancreatic pseudotumors: non-neoplastic solid lesions of the pancreas that clinically mimic pancreas cancerN Volkan Adsay
Karmanos Cancer Institute Wayne State University, Detroit, Michigan, USA
Semin Diagn Pathol 21:260-7. 2004..Nonspecific terms such as "inflammatory pseudotumor" ought to be avoided, and every attempt should be made to classify a "pseudotumor" into a more specific diagnostic category discussed above... - Paraduodenal pancreatitis: a clinico-pathologically distinct entity unifying "cystic dystrophy of heterotopic pancreas", "para-duodenal wall cyst", and "groove pancreatitis"N V Adsay
Karmanos Cancer Institute Wayne State University, Detroit, Michigan, USA
Semin Diagn Pathol 21:247-54. 2004..In conclusion, these clinicopathologic findings characterize a distinctive process that can be referred to as paraduodenal pancreatitis... - Ductal neoplasia of the pancreas: nosologic, clinicopathologic, and biologic aspectsNazmi Volkan Adsay
The Karmanos Cancer Institute, Harper University Hospital, Wayne State University, Detroit, MI 48201, USA
Semin Radiat Oncol 15:254-64. 2005..Understanding the molecular mechanisms of ductal carcinogenesis will help develop more efficient prevention and therapy of these tumors... - A proposal for a new and more practical grading scheme for pancreatic ductal adenocarcinomaN Volkan Adsay
Department of Pathology, Karmanos Cancer Institute and Harper University Hospital, Wayne State University, 3990 John R Street, Detroit, MI 48201, USA
Am J Surg Pathol 29:724-33. 2005..Most importantly, it is clinically relevant with good prognostic value. Lastly, it is also applicable for use in research, by utilizing "patterns," even in small specimens like microarrays or biopsies... - Pathologically and biologically distinct types of epithelium in intraductal papillary mucinous neoplasms: delineation of an "intestinal" pathway of carcinogenesis in the pancreasN Volkan Adsay
Departments of Pathology, Karmanos Cancer Institute and Wayne State University, Detroit, MI 48201, USA
Am J Surg Pathol 28:839-48. 2004.... - Secondary tumors of the pancreas: an analysis of a surgical and autopsy database and review of the literatureN Volkan Adsay
Department of Pathology, The Karmanos Cancer Institute and Wayne State University, Harper Hospital, 3990 John R Street, Detroit, MI 48201, USA
Virchows Arch 444:527-35. 2004..These are predominantly hematopoietic malignancies or carcinomas of renal or gastric origin. Secondary tumors should be entertained in both the clinical and pathological differential diagnosis of pancreatic neoplasia... - Pathogenesis of colloid (pure mucinous) carcinoma of exocrine organs: Coupling of gel-forming mucin (MUC2) production with altered cell polarity and abnormal cell-stroma interaction may be the key factor in the morphogenesis and indolent behavior of colloN Volkan Adsay
Department of Pathology, Karamanos Cancer Institute and Wayne State University, Detroit, Michigan 48201, USA
Am J Surg Pathol 27:571-8. 2003..This distinctive mucin, accumulated in the stroma surrounding the CC cells, may act as a containing factor, slackening the spread of the cells... - The dichotomy in the preinvasive neoplasia to invasive carcinoma sequence in the pancreas: differential expression of MUC1 and MUC2 supports the existence of two separate pathways of carcinogenesisN Volkan Adsay
Department of Pathology, Karmanos Cancer Institute, Detroit, Michigan, USA
Mod Pathol 15:1087-95. 2002.... - Lymphoepithelial cysts of the pancreas: a report of 12 cases and a review of the literatureN Volkan Adsay
Department of Pathology, Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan, USA
Mod Pathol 15:492-501. 2002..LECs are not associated with the clinical syndromes that are seen with their analogues in the salivary glands... - Colloid (mucinous noncystic) carcinoma of the pancreasN V Adsay
Department of Pathology, Karmanos Cancer Institute, Harper Hospital, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
Am J Surg Pathol 25:26-42. 2001..The luminalization of the basal aspects of the tumor cells may be the cause of stromal mucin accumulation that characterizes colloid carcinoma and may act as a containing factor... - Squamous-lined cysts of the pancreas: lymphoepithelial cysts, dermoid cysts (teratomas), and accessory-splenic epidermoid cystsN V Adsay
Department of Pathology, The Karmanos Cancer Institute Detroit Medical Center, Wayne State University, MI 48076, USA
Semin Diagn Pathol 17:56-65. 2000..Subepithelial lymphoid tissue is not a feature. They are sometimes complicated by suppurative infections. The importance of these lesions is in their distinction from other cystic neoplasms, especially mucinous cystic tumors... - Mixed epithelial and stromal tumor of the kidneyN V Adsay
Harper Hospital and Karmanos Cancer Institute, Wayne State University, Detroit, Michigan 48201, USA
Am J Surg Pathol 24:958-70. 2000..We think this entity is a benign composite neoplasm in which stroma and epithelium are both integral neoplastic components... - Cystic forms of typically solid pancreatic tumorsN V Adsay
Department of Pathology, The Karmanos Cancer Institute, Harper Hospital, Wayne State University School of Medicine, Detroit, MI 48201, USA
Semin Diagn Pathol 17:81-8. 2000.... 
Multifocal neoplastic precursor lesions associated with lobular atrophy of the pancreas in patients having a strong family history of pancreatic cancerKieran Brune
Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA
Am J Surg Pathol 30:1067-76. 2006..The multifocal nature of familial pancreatic neoplasia suggests that surveillance of these patients is warranted after partial pancreatectomy...- Preferential expression of MUC6 in oncocytic and pancreatobiliary types of intraductal papillary neoplasms highlights a pyloropancreatic pathway, distinct from the intestinal pathway, in pancreatic carcinogenesisOlca Basturk
Departments of Pathology, New York University, NY, USA
Am J Surg Pathol 34:364-70. 2010.... 
Isolated solitary ducts (naked ducts) in adipose tissue: a specific but underappreciated finding of pancreatic adenocarcinoma and one of the potential reasons of understaging and high recurrence rateSudeshna Bandyopadhyay
Department of Pathology, Wayne State University and Karmanos Cancer Institute, Detroit, MI, USA
Am J Surg Pathol 33:425-9. 2009..6% of pancreatic resections when peripancreatic soft tissues away from the tumor are sampled, is a very specific finding for carcinoma that may be instrumental in the diagnosis and staging of carcinoma as well as margin evaluation...