Bernadette C Victor

Summary

Affiliation: Wayne State University
Country: USA

Publications

  1. ncbi request reprint Cysteine cathepsin non-inhibitory binding partners: modulating intracellular trafficking and function
    Bernadette C Victor
    Department of Pharmacology and Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Biol Chem 388:1131-40. 2007
  2. pmc Fibroblast hepatocyte growth factor promotes invasion of human mammary ductal carcinoma in situ
    Christopher Jedeszko
    Department of Pharmacology, Wayne State University, Detroit, Michigan, USA
    Cancer Res 69:9148-55. 2009
  3. pmc Inhibition of cathepsin B activity attenuates extracellular matrix degradation and inflammatory breast cancer invasion
    Bernadette C Victor
    Department of Pharmacology, Wayne State University, Detroit, Michigan 48201, USA
    Breast Cancer Res 13:R115. 2011
  4. pmc 3D/4D functional imaging of tumor-associated proteolysis: impact of microenvironment
    Kamiar Moin
    Department of Pharmacology, Wayne State University School of Medicine, Detroit, Michigan, USA
    Methods Enzymol 506:175-94. 2012

Collaborators

Detail Information

Publications4

  1. ncbi request reprint Cysteine cathepsin non-inhibitory binding partners: modulating intracellular trafficking and function
    Bernadette C Victor
    Department of Pharmacology and Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Biol Chem 388:1131-40. 2007
    ..Mechanisms for altered localization are not well understood, but do include the interaction of cysteine cathepsins with binding partners that modulate intracellular trafficking and association with specific regions on the cell surface...
  2. pmc Fibroblast hepatocyte growth factor promotes invasion of human mammary ductal carcinoma in situ
    Christopher Jedeszko
    Department of Pharmacology, Wayne State University, Detroit, Michigan, USA
    Cancer Res 69:9148-55. 2009
    ....
  3. pmc Inhibition of cathepsin B activity attenuates extracellular matrix degradation and inflammatory breast cancer invasion
    Bernadette C Victor
    Department of Pharmacology, Wayne State University, Detroit, Michigan 48201, USA
    Breast Cancer Res 13:R115. 2011
    ..Breast cancer invasion has been linked to proteolytic activity at the tumor cell surface. Here we explored a role for active cathepsin B on the cell surface in the invasiveness of IBC...
  4. pmc 3D/4D functional imaging of tumor-associated proteolysis: impact of microenvironment
    Kamiar Moin
    Department of Pharmacology, Wayne State University School of Medicine, Detroit, Michigan, USA
    Methods Enzymol 506:175-94. 2012
    ..Of course, all assays have limitations; however, we suggest that the techniques discussed here will, with attention to their limitations, be useful as a screen for drugs to target the invasive phenotype of tumors...