Nandor Gabor Than

Summary

Affiliation: Wayne State University
Country: USA

Publications

  1. pmc A role for mannose-binding lectin, a component of the innate immune system in pre-eclampsia
    Nandor Gabor Than
    Perinatology Research Branch, NICHD NIH DHHS, Wayne State University Hutzel Women s Hospital, 3990 John R, Box 4, Detroit, MI 48201, USA
    Am J Reprod Immunol 60:333-45. 2008
  2. pmc Galectins: guardians of eutherian pregnancy at the maternal-fetal interface
    Nandor Gabor Than
    Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD, National Institutes of Health NIH, Department of Health and Human Services DHHS, Detroit, MI, USA
    Trends Endocrinol Metab 23:23-31. 2012
  3. pmc Chorioamnionitis and increased galectin-1 expression in PPROM --an anti-inflammatory response in the fetal membranes?
    Nandor Gabor Than
    Perinatology Research Branch, NICHD NIH DHHS, Wayne State University Hutzel Women s Hospital, 3990 John R, Box 4, Detroit, MI 48201, USA
    Am J Reprod Immunol 60:298-311. 2008
  4. pmc Placental protein 13 (galectin-13) has decreased placental expression but increased shedding and maternal serum concentrations in patients presenting with preterm pre-eclampsia and HELLP syndrome
    Nandor Gabor Than
    First Department of Obstetrics and Gynecology, Semmelweis University, 27 Baross Street, 1088, Budapest, Hungary
    Virchows Arch 453:387-400. 2008
  5. pmc PP13, maternal ABO blood groups and the risk assessment of pregnancy complications
    Nandor Gabor Than
    First Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary
    PLoS ONE 6:e21564. 2011
  6. pmc Embryo-placento-maternal interaction and biomarkers: from diagnosis to therapy--a workshop report
    N G Than
    First Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary
    Placenta 28:S107-10. 2007
  7. pmc Severe preeclampsia is characterized by increased placental expression of galectin-1
    Nandor Gabor Than
    Perinatology Research Branch, NICHD, NIH, DHHS, Detroit, Michigan 48201, USA
    J Matern Fetal Neonatal Med 21:429-42. 2008
  8. pmc A link between a hemostatic disorder and preterm PROM: a role for tissue factor and tissue factor pathway inhibitor
    Offer Erez
    Perinatology Research Branch, NICHD, NIH, DHHS, Detroit, Michigan, USA
    J Matern Fetal Neonatal Med 21:732-44. 2008
  9. pmc Characterization of the fetal blood transcriptome and proteome in maternal anti-fetal rejection: evidence of a distinct and novel type of human fetal systemic inflammatory response
    Joonho Lee
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, MD, Detroit, MI, USA
    Am J Reprod Immunol 70:265-84. 2013
  10. pmc Amniotic fluid sTREM-1 in normal pregnancy, spontaneous parturition at term and preterm, and intra-amniotic infection/inflammation
    Juan Pedro Kusanovic
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, Maryland, USA
    J Matern Fetal Neonatal Med 23:34-47. 2010

Collaborators

Detail Information

Publications64

  1. pmc A role for mannose-binding lectin, a component of the innate immune system in pre-eclampsia
    Nandor Gabor Than
    Perinatology Research Branch, NICHD NIH DHHS, Wayne State University Hutzel Women s Hospital, 3990 John R, Box 4, Detroit, MI 48201, USA
    Am J Reprod Immunol 60:333-45. 2008
    ..The objective of this study was to determine maternal plasma MBL concentrations in normal pregnant women and patients with pre-eclampsia...
  2. pmc Galectins: guardians of eutherian pregnancy at the maternal-fetal interface
    Nandor Gabor Than
    Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD, National Institutes of Health NIH, Department of Health and Human Services DHHS, Detroit, MI, USA
    Trends Endocrinol Metab 23:23-31. 2012
    ....
  3. pmc Chorioamnionitis and increased galectin-1 expression in PPROM --an anti-inflammatory response in the fetal membranes?
    Nandor Gabor Than
    Perinatology Research Branch, NICHD NIH DHHS, Wayne State University Hutzel Women s Hospital, 3990 John R, Box 4, Detroit, MI 48201, USA
    Am J Reprod Immunol 60:298-311. 2008
    ..Galectin-1 can regulate immune responses upon infection and inflammation. We determined galectin-1 expression in the chorioamniotic membranes and its changes during histological chorioamnionitis...
  4. pmc Placental protein 13 (galectin-13) has decreased placental expression but increased shedding and maternal serum concentrations in patients presenting with preterm pre-eclampsia and HELLP syndrome
    Nandor Gabor Than
    First Department of Obstetrics and Gynecology, Semmelweis University, 27 Baross Street, 1088, Budapest, Hungary
    Virchows Arch 453:387-400. 2008
    ..In conclusion, parallel to its decreased placental expression, an augmented membrane shedding of PP13 contributes to the increased third trimester maternal serum PP13 concentrations in women with preterm pre-eclampsia and HELLP syndrome...
  5. pmc PP13, maternal ABO blood groups and the risk assessment of pregnancy complications
    Nandor Gabor Than
    First Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary
    PLoS ONE 6:e21564. 2011
    ..Placental Protein 13 (PP13), an early biomarker of preeclampsia, is a placenta-specific galectin that binds beta-galactosides, building-blocks of ABO blood-group antigens, possibly affecting its bioavailability in blood...
  6. pmc Embryo-placento-maternal interaction and biomarkers: from diagnosis to therapy--a workshop report
    N G Than
    First Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary
    Placenta 28:S107-10. 2007
  7. pmc Severe preeclampsia is characterized by increased placental expression of galectin-1
    Nandor Gabor Than
    Perinatology Research Branch, NICHD, NIH, DHHS, Detroit, Michigan 48201, USA
    J Matern Fetal Neonatal Med 21:429-42. 2008
    ..To test this hypothesis, we studied placental galectin-1 mRNA and protein expression and localization in women with preeclampsia (PE) and in those who delivered a small-for-gestational age (SGA) neonate...
  8. pmc A link between a hemostatic disorder and preterm PROM: a role for tissue factor and tissue factor pathway inhibitor
    Offer Erez
    Perinatology Research Branch, NICHD, NIH, DHHS, Detroit, Michigan, USA
    J Matern Fetal Neonatal Med 21:732-44. 2008
    ..A decidual hemostatic disorder may link vaginal bleeding, PPROM and placental abruption. This study was conducted to determine the behaviour of maternal TF and its natural inhibitor, the tissue factor pathway inhibitor (TFPI) in PPROM...
  9. pmc Characterization of the fetal blood transcriptome and proteome in maternal anti-fetal rejection: evidence of a distinct and novel type of human fetal systemic inflammatory response
    Joonho Lee
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, MD, Detroit, MI, USA
    Am J Reprod Immunol 70:265-84. 2013
    ....
  10. pmc Amniotic fluid sTREM-1 in normal pregnancy, spontaneous parturition at term and preterm, and intra-amniotic infection/inflammation
    Juan Pedro Kusanovic
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, Maryland, USA
    J Matern Fetal Neonatal Med 23:34-47. 2010
    ..The aim of this study was to determine the effect of gestational age, parturition (term and preterm) and IAI in the amniotic fluid (AF) concentrations of sTREM-1...
  11. pmc Amniotic fluid fetal hemoglobin in normal pregnancies and pregnancies complicated with preterm labor or prelabor rupture of membranes
    Edi Vaisbuch
    Perinatology Research Branch, NICHD, NIH, DHHS, Wayne State University, Hutzel Women s Hospital, 3990 John R, Box 4, Detroit, MI 48201, USA
    J Matern Fetal Neonatal Med 22:388-97. 2009
    ....
  12. pmc Adiponectin in amniotic fluid in normal pregnancy, spontaneous labor at term, and preterm labor: a novel association with intra-amniotic infection/inflammation
    Shali Mazaki-Tovi
    Perinatology Research Branch, Intramural Division, NICHD NIH DHHS, Hutzel Women s Hospital, Bethesda, Maryland, USA
    J Matern Fetal Neonatal Med 23:120-30. 2010
    ....
  13. pmc High tissue factor activity and low tissue factor pathway inhibitor concentrations in patients with preterm labor
    Offer Erez
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, MD, USA
    J Matern Fetal Neonatal Med 23:23-33. 2010
    ..The aims of this study were to determine whether spontaneous PTL with intact membranes is associated with changes in the maternal plasma concentrations and activity of TF as well as tissue factor pathway inhibitor (TFPI)...
  14. pmc Visfatin/Pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture of membranes: an association with subclinical intrauterine infection in preterm parturition
    Shali Mazaki-Tovi
    Perinatology Research Branch, Intramural Division, NICHD NIH DHHS, Hutzel Women s Hospital, Bethesda, MD, USA
    J Perinat Med 36:485-96. 2008
    ....
  15. pmc Over-expression of the thrombin receptor (PAR-1) in the placenta in preeclampsia: a mechanism for the intersection of coagulation and inflammation
    Offer Erez
    Perinatology Research Branch, NICHD, NIH, DHHS, Bethesda, Maryland, USA
    J Matern Fetal Neonatal Med 21:345-55. 2008
    ..The aim of this study was to determine whether preterm PE is associated with changes in placental expression of PAR-1...
  16. pmc Placental protein 13 (PP13/galectin-13) undergoes lipid raft-associated subcellular redistribution in the syncytiotrophoblast in preterm preeclampsia and HELLP syndrome
    Andrea Balogh
    Immunology Research Group of the Hungarian Academy of Sciences, Budapest, Hungary
    Am J Obstet Gynecol 205:156.e1-14. 2011
    ..To investigate placental protein 13 (PP13) localization in relation to cytoskeleton and lipid rafts in preeclampsia and HELLP syndrome...
  17. ncbi request reprint The anti-inflammatory limb of the immune response in preterm labor, intra-amniotic infection/inflammation, and spontaneous parturition at term: a role for interleukin-10
    Francesca Gotsch
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, Maryland, USA
    J Matern Fetal Neonatal Med 21:529-47. 2008
    ..The objectives of this study were to determine whether there is a relationship between amniotic fluid concentrations of IL-10 and gestational age, parturition (at term and preterm), and intra-amniotic infection/inflammation (IAI)...
  18. pmc Emergence of hormonal and redox regulation of galectin-1 in placental mammals: implication in maternal-fetal immune tolerance
    Nandor Gabor Than
    Perinatology Research Branch, National Institute of Child Health and Human Development, National Institutes of Health, and Department of Health and Human Services, Detroit, MI 48201, USA
    Proc Natl Acad Sci U S A 105:15819-24. 2008
    ....
  19. pmc A role for CXCL13 (BCA-1) in pregnancy and intra-amniotic infection/inflammation
    Chia Ling Nhan-Chang
    Perinatology Research Branch, Intramural Division, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NICHD NIH DHHS, Hutzel Women s Hospital, Detroit, MI 48201, USA
    J Matern Fetal Neonatal Med 21:763-75. 2008
    ....
  20. pmc Retinol binding protein 4: an adipokine associated with intra-amniotic infection/inflammation
    Edi Vaisbuch
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, Maryland, USA
    J Matern Fetal Neonatal Med 23:111-9. 2010
    ..The aim of this study was to determine whether RBP4 is present in AF, and if its concentrations change with gestational age, in the presence of labor, and intra-amniotic infection/inflammation (IAI) in patients with spontaneous PTL...
  21. pmc Maternal serum soluble CD30 is increased in normal pregnancy, but decreased in preeclampsia and small for gestational age pregnancies
    Juan Pedro Kusanovic
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, Maryland, USA
    J Matern Fetal Neonatal Med 20:867-78. 2007
    ..The objective of this study was to determine whether the maternal serum concentration of sCD30 changes with normal pregnancy, as well as in mothers with preeclampsia and those who deliver SGA neonates...
  22. doi request reprint Fetal membranes as an interface between inflammation and metabolism: increased aquaporin 9 expression in the presence of spontaneous labor at term and chorioamnionitis
    Pooja Mittal
    Perinatology Research Branch, NICHD, NIH, DHHS, Detroit, Michigan, USA
    J Matern Fetal Neonatal Med 22:1167-75. 2009
    ....
  23. pmc Resistin in amniotic fluid and its association with intra-amniotic infection and inflammation
    Juan Pedro Kusanovic
    Perinatology Research Branch, NICHD NIH DHHS, Wayne State University HutzelWomen s Hospital, Detroit, MI 48201, USA
    J Matern Fetal Neonatal Med 21:902-16. 2008
    ....
  24. pmc Amniotic fluid angiopoietin-2 in term and preterm parturition, and intra-amniotic infection/inflammation
    Percy Pacora
    Perinatology Research Branch, NICHD NIH DHHS, Wayne State University Hutzel Women s Hospital, Detroit, MI 48201, USA
    J Perinat Med 37:503-11. 2009
    ....
  25. pmc The change in concentrations of angiogenic and anti-angiogenic factors in maternal plasma between the first and second trimesters in risk assessment for the subsequent development of preeclampsia and small-for-gestational age
    Offer Erez
    Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, DHHS, Bethesda, Maryland, USA
    J Matern Fetal Neonatal Med 21:279-87. 2008
    ....
  26. pmc Evidence of the involvement of caspase-1 under physiologic and pathologic cellular stress during human pregnancy: a link between the inflammasome and parturition
    Francesca Gotsch
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, Maryland, USA
    J Matern Fetal Neonatal Med 21:605-16. 2008
    ..The objectives of this study were to determine whether there is a relationship between amniotic fluid concentrations of caspase-1 and gestational age, parturition (term and preterm), and intra-amniotic infection/inflammation (IAI)...
  27. pmc Changes in amniotic fluid concentration of thrombin-antithrombin III complexes in patients with preterm labor: evidence of an increased thrombin generation
    Offer Erez
    Perinatology Research Branch, NICHD, NIH, DHHS, Bethesda, Maryland, USA
    J Matern Fetal Neonatal Med 22:971-82. 2009
    ..The aim of this study was to determine whether intra-amniotic infection/inflammation (IAI) is associated with increased amniotic fluid (AF) thrombin generation in women with preterm and term deliveries...
  28. pmc Could alterations in maternal plasma visfatin concentration participate in the phenotype definition of preeclampsia and SGA?
    Shali Mazaki-Tovi
    Perinatology Research Branch, Intramural Division, NICHD NIH DHHS, Hutzel Women s Hospital, Bethesda, MD, and Detroit, MI 48201, USA
    J Matern Fetal Neonatal Med 23:857-68. 2010
    ..Visfatin is a novel adipocytokine with metabolic and immunomodulating properties. The objective of this study was to determine whether preeclampsia and SGA are associated with alterations in maternal circulating visfatin concentrations...
  29. doi request reprint Maternal anti-protein Z antibodies in pregnancies complicated by pre-eclampsia, SGA and fetal death
    Offer Erez
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, Maryland, USA
    J Matern Fetal Neonatal Med 22:662-71. 2009
    ..The objective of this study was to determine the maternal plasma concentration of APZ-AB in women with a normal pregnancy, and patients with PE, an SGA neonate or a FD...
  30. doi request reprint Maternal floor infarction/massive perivillous fibrin deposition: a manifestation of maternal antifetal rejection?
    Roberto Romero
    Perinatology Research Branch, NICHD NIH DHHS, Detroit, MI, Bethesda, MD, USA
    Am J Reprod Immunol 70:285-98. 2013
    ..A tendency to recur in subsequent pregnancies has been reported. This study was conducted to determine whether this complication of pregnancy could reflect maternal antifetal rejection...
  31. pmc Premature labor: a state of platelet activation?
    Offer Erez
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, MD 20892, USA
    J Perinat Med 36:377-87. 2008
    ..This study was undertaken to determine whether premature labor is associated with changes in the maternal plasma concentration of soluble CD40 ligand (sCD40L), a marker of platelet activation...
  32. doi request reprint The maternal plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated in SGA and the magnitude of the increase relates to Doppler abnormalities in the maternal and fetal circulation
    Tinnakorn Chaiworapongsa
    Perinatology Research Branch, National Institute of Child Health and Human Development, NIH DHHS, Bethesda, MD 20892, USA
    J Matern Fetal Neonatal Med 21:25-40. 2008
    ....
  33. pmc Preeclampsia and small-for-gestational age are associated with decreased concentrations of a factor involved in angiogenesis: soluble Tie-2
    Francesca Gotsch
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, Maryland, USA
    J Matern Fetal Neonatal Med 21:389-402. 2008
    ..The purpose of this study was to determine whether patients with preeclampsia and mothers who deliver a SGA neonate have changes in the plasma concentrations of sTie-2...
  34. pmc First-trimester maternal serum PP13 in the risk assessment for preeclampsia
    Roberto Romero
    Department of Health and Human Services, Perinatology Research Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    Am J Obstet Gynecol 199:122.e1-122.e11. 2008
    ..The objective of the study was to determine whether first-trimester maternal serum placental protein 13 (PP13) concentrations can be used in the risk assessment for preeclampsia...
  35. pmc Maternal visfatin concentration in normal pregnancy
    Shali Mazaki-Tovi
    Perinatology Research Branch, Intramural Division, NICHD NIH DHHS, Bethesda, MD, USA
    J Perinat Med 37:206-17. 2009
    ..The aim of this study was to determine whether there are changes in the maternal plasma concentration of visfatin with advancing gestation and as a function of maternal weight...
  36. pmc Interleukin-33 in the human placenta
    Vanessa Topping
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, MD 20892, USA
    J Matern Fetal Neonatal Med 26:327-38. 2013
    ..The purpose of this study was to determine whether IL-33 is expressed in the human placenta and to investigate its expression in the context of acute and chronic chorioamnionitis...
  37. pmc Tissue factor and its natural inhibitor in pre-eclampsia and SGA
    Offer Erez
    Perinatology Research Branch, NICHD, NIH, DHHS, Detroit, MI 48201, USA
    J Matern Fetal Neonatal Med 21:855-69. 2008
    ..The aim of this study was to determine the maternal plasma concentrations of TF and its primary inhibitor, tissue factor pathway inhibitor (TFPI), in women who delivered small for gestational age (SGA) neonates, and in pre-eclampsia...
  38. pmc Retinol binding protein 4--a novel association with early-onset preeclampsia
    Edi Vaisbuch
    Intramural Division, Perinatology Research Branch, NICHD NIH DHHS, Hutzel Women s Hospital, Bethesda, MD, USA
    J Perinat Med 38:129-39. 2010
    ..The aim of this study was to determine whether there are changes in maternal plasma concentrations of RBP4 in patients with PE and in those with an SGA neonate or FD...
  39. pmc Mitochondrial manganese superoxide dismutase mRNA expression in human chorioamniotic membranes and its association with labor, inflammation, and infection
    Nandor Gabor Than
    Perinatology Research Branch, NICHD, NIH, DHHS, Detroit, Michigan 48201, USA
    J Matern Fetal Neonatal Med 22:1000-13. 2009
    ..Therefore, the aim of this study was to determine the differences in Mn SOD mRNA expression in the fetal membranes in patients with term and preterm labor (PTL) as well as in acute chorioamnionitis...
  40. doi request reprint The molecular basis for sonographic cervical shortening at term: identification of differentially expressed genes and the epithelial-mesenchymal transition as a function of cervical length
    Sonia S Hassan
    Department of Obstetrics and Gynecology, Wayne State University Hutzel Women s Hospital, 3990 John R, Detroit, MI 48201, USA
    Am J Obstet Gynecol 203:472.e1-472.e14. 2010
    ..The purpose of this study was to determine whether cervical shortening of a ripe cervix at term is associated with changes in the cervical transcriptome...
  41. pmc CXCL10/IP-10: a missing link between inflammation and anti-angiogenesis in preeclampsia?
    Francesca Gotsch
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, Maryland, USA
    J Matern Fetal Neonatal Med 20:777-92. 2007
    ..The aim of this study was to determine whether preeclampsia and delivery of a small for gestational age (SGA) neonate are associated with changes in maternal serum concentration of CXCL10/IP-10...
  42. pmc Differential expression pattern of genes encoding for anti-microbial peptides in the fetal membranes of patients with spontaneous preterm labor and intact membranes and those with preterm prelabor rupture of the membranes
    Offer Erez
    Perinatology Research Branch, NICHD, NIH, DHHS, Detroit, Michigan, USA
    J Matern Fetal Neonatal Med 22:1103-15. 2009
    ....
  43. pmc Characterization of the transcriptome of chorioamniotic membranes at the site of rupture in spontaneous labor at term
    Chia Ling Nhan-Chang
    Perinatology Research Branch, Intramural Division, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NICHD NIH DHHS, Bethesda, MD, USA
    Am J Obstet Gynecol 202:462.e1-41. 2010
    ..The purpose of this study was to compare the transcriptome between the site of membrane rupture and the chorioamniotic membranes away from the site of rupture...
  44. pmc Amniotic fluid heat shock protein 70 concentration in histologic chorioamnionitis, term and preterm parturition
    Tinnakorn Chaiworapongsa
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, Maryland, USA
    J Matern Fetal Neonatal Med 21:449-61. 2008
    ..This study was conducted to determine the changes in amniotic fluid HSP70 concentrations during pregnancy, term and preterm parturition, intra-amniotic infection (IAI), and histologic chorioamnionitis...
  45. pmc Visfatin in human pregnancy: maternal gestational diabetes vis-à-vis neonatal birthweight
    Shali Mazaki-Tovi
    Perinatology Research Branch, Intramural Division, NICHD NIH DHHS, Bethesda, MD, USA
    J Perinat Med 37:218-31. 2009
    ..The aims of this study were to determine whether there is an association between maternal plasma visfatin concentration, GDM, and a large-for-gestational-age (LGA) newborn...
  46. pmc Maternal serum soluble CD30 is increased in pregnancies complicated with acute pyelonephritis
    Juan Pedro Kusanovic
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, Maryland, USA
    J Matern Fetal Neonatal Med 20:803-11. 2007
    ..The objective of this study was to determine whether there are changes in the serum concentration of sCD30 in pregnant women with pyelonephritis...
  47. pmc Elephant transcriptome provides insights into the evolution of eutherian placentation
    Zhuo Cheng Hou
    Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development NIH DHHS, Detroit, Michigan, USA
    Genome Biol Evol 4:713-25. 2012
    ....
  48. pmc Exodus-1 (CCL20): evidence for the participation of this chemokine in spontaneous labor at term, preterm labor, and intrauterine infection
    Neil Hamill
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, Maryland, USA
    J Perinat Med 36:217-27. 2008
    ....
  49. pmc Placental growth hormone is increased in the maternal and fetal serum of patients with preeclampsia
    Pooja Mittal
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, Maryland, USA
    J Matern Fetal Neonatal Med 20:651-9. 2007
    ..The purpose of this study was to determine whether the maternal serum concentrations of PGH change in women with preeclampsia (PE), women with PE who deliver a small for gestational age neonate (PE + SGA), and those with SGA alone...
  50. doi request reprint Maternal plasma soluble TRAIL is decreased in preeclampsia
    Piya Chaemsaithong
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, MD, and Detroit, MI, USA
    J Matern Fetal Neonatal Med 27:217-27. 2014
    ..The aim of this study was to determine whether maternal plasma concentrations of sTRAIL and CRP differ between women with PE and those with uncomplicated pregnancies...
  51. pmc Recurrent preterm birth
    Shali Mazaki-Tovi
    Perinatology Research Branch, Intramural Division, NICHD NIH DHHS, Hutzel Women s Hospital, Bethesda, MD, USA
    Semin Perinatol 31:142-58. 2007
    ..Patients with a history of an indicated preterm birth are at risk not only for recurrence of this subtype, but also for spontaneous preterm birth. Individuals of black origin have a higher rate of recurrent preterm birth...
  52. pmc Methylome of fetal and maternal monocytes and macrophages at the feto-maternal interface
    Sun Young Kim
    Perinatology Research Branch, NICHD NIH DHHS, Detroit, MI 48201, USA
    Am J Reprod Immunol 68:8-27. 2012
    ..This study was conducted to compare the DNA methylome of maternal and fetal monocytes, dMφ, and HC and thereby to determine the immunobiological importance of DNA methylation in pregnancy...
  53. ncbi request reprint Normal and abnormal transformation of the spiral arteries during pregnancy
    Jimmy Espinoza
    Perinatology Research Branch, NICHD, NIH, DHHS, Bethesda, MD 20892, USA
    J Perinat Med 34:447-58. 2006
    ..Finally, we comment on the use of uterine artery Doppler velocimetry as a surrogate marker of chronic uteroplacental ischemia...
  54. pmc Chronic chorioamnionitis displays distinct alterations of the amniotic fluid proteome
    Giovanna Ogge
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, MD, USA
    J Pathol 223:553-65. 2011
    ....
  55. pmc Maternal serum adiponectin multimers in preeclampsia
    Shali Mazaki-Tovi
    Perinatology Research Branch, Intramural Division, NICHD NIH DHHS, Hutzel Women s Hospital, Bethesda, MD, USA
    J Perinat Med 37:349-63. 2009
    ..The aim of this study was to determine whether preeclampsia is associated with changes in circulating adiponectin multimers...
  56. pmc Changes of placental syndecan-1 expression in preeclampsia and HELLP syndrome
    Szilvia Szabó
    Department of Morphology and Physiology, Faculty of Health Sciences, Semmelweis University, Budapest, Hungary
    Virchows Arch 463:445-58. 2013
    ..This phenomenon may be related to the disturbed syncytiotrophoblastic cortical actin cytoskeleton and associated with maternal anti-angiogenic and pro-inflammatory states in these syndromes...
  57. pmc Maternal serum concentrations of the chemokine CXCL10/IP-10 are elevated in acute pyelonephritis during pregnancy
    Francesca Gotsch
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, Maryland, USA
    J Matern Fetal Neonatal Med 20:735-44. 2007
    ..The purpose of this study was to determine whether maternal serum concentrations of CXCL10/IP-10 change in patients with acute pyelonephritis during pregnancy...
  58. pmc Analysis and correction of crosstalk effects in pathway analysis
    Michele Donato
    Computer Science Department, Wayne State University, Detroit, Michigan 48084, USA
    Genome Res 23:1885-93. 2013
    ..This method is expected to allow a better understanding of individual experiment results, as well as a more refined definition of the existing signaling pathways for specific phenotypes. ..
  59. doi request reprint Detection of anti-HLA antibodies in maternal blood in the second trimester to identify patients at risk of antibody-mediated maternal anti-fetal rejection and spontaneous preterm delivery
    Joonho Lee
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, MD, USA
    Am J Reprod Immunol 70:162-75. 2013
    ..The objective of this study was to determine whether the presence of human leukocyte antigen (HLA) panel-reactive antibodies (PRA) during the second trimester increases the risk of spontaneous preterm delivery...
  60. doi request reprint Soluble ST2, a modulator of the inflammatory response, in preterm and term labor
    Tamara Stampalija
    Perinatology Research Branch, NICHD NIH DHHS, Bethesda, Maryland, and Detroit, Michigan, USA
    J Matern Fetal Neonatal Med 27:111-21. 2014
    ....
  61. pmc A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death
    Nandor Gabor Than
    Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Detroit, MI 48201, USA
    Proc Natl Acad Sci U S A 106:9731-6. 2009
    ....
  62. pmc Leptin receptor (LEPR) SNP polymorphisms in HELLP syndrome patients determined by quantitative real-time PCR and melting curve analysis
    Tibor Varkonyi
    1st Department of Obstetrics and Gynecology, Semmelweis University, 1088 Budapest, Hungary
    BMC Med Genet 11:25. 2010
    ..We decided to study four leptin receptor (LEPR) SNP polymorphisms in HELLP syndrome patients by using quantitative real-time PCR and melting curve analysis...
  63. doi request reprint Leptin gene (TTTC)(n) microsatellite polymorphism in pre-eclampsia and HELLP syndrome
    Balint Nagy
    First Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary
    Clin Chem Lab Med 47:1033-7. 2009
    ....
  64. pmc Adaptive history of single copy genes highly expressed in the term human placenta
    Zhuocheng Hou
    Perinatology Research Branch, NICHD NIH DHHS Wayne State University, Detroit, MI 48201, USA
    Genomics 93:33-41. 2009
    ..Adaptations in genes highly expressed in human placenta are attractive candidates for functional and clinical studies...