Research Topics
| JEFFREY STANLEYSummaryAffiliation: Wayne State University Country: USA Publications
Research Grants
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Detail Information
Publications
Evidence of developmental alterations in cortical and subcortical regions of children with attention-deficit/hyperactivity disorder: a multivoxel in vivo phosphorus 31 spectroscopy studyJeffrey A Stanley
Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, Michigan, USA
Arch Gen Psychiatry 65:1419-28. 2008..In vivo phosphorus 31 magnetic resonance spectroscopy ((31)P MRS) is a noninvasive neuroimaging approach that is sensitive in assessing developmental changes of overproducing/pruning of synapses...
Reduced N-acetyl-aspartate levels in schizophrenia patients with a younger onset age: a single-voxel 1H spectroscopy studyJeffrey A Stanley
Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, 48201, United States
Schizophr Res 93:23-32. 2007....
Regionally specific alterations in membrane phospholipids in children with ADHD: An in vivo 31P spectroscopy studyJeffrey A Stanley
Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, University Health Center 9B-28, 4201 St. Antoine Street, Detroit, MI 48201, USA
Psychiatry Res 148:217-21. 2006..No differences were noted in the ST. These deficits in membrane phospholipid (MPL) precursor levels suggest reduced mass of cellular MPLs due to a possible underdevelopment of neuronal processes and synapses in ADHD...- Distinguishing between major depressive disorder and obsessive-compulsive disorder in children by measuring regional cortical thicknessErin Fallucca
Department of Psychiatry and Behavioral Neurosciences, Wayne State University, and Children s Hospital of Michigan, Detroit, Michigan, USA
Arch Gen Psychiatry 68:527-33. 2011..Cortical abnormalities have been noted in previous studies of major depressive disorder (MDD)... - An MRI and proton spectroscopy study of the thalamus in children with autismAntonio Y Hardan
Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA
Psychiatry Res 163:97-105. 2008..Further investigations of this structure are warranted, since it plays an important role in information processing as part of the cortico-thalamo-cortical pathways... - 1H MRS study of dorsolateral prefrontal cortex in healthy individuals before and after lithium administrationPaolo Brambilla
Division of Mood and Anxiety Disorders, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
Neuropsychopharmacology 29:1918-24. 2004.... - Brain-derived neurotrophic factor val66met polymorphism affects prefrontal energy metabolism in bipolar disorderBenicio N Frey
Department of Psychiatry, Psychiatric Genetics Research Center, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
Neuroreport 18:1567-70. 2007..These results indicate that bipolar disorder met-carriers have abnormal energy metabolism in the left dorsolateral prefrontal cortex... - Low levels of N-acetyl aspartate in the left dorsolateral prefrontal cortex of pediatric bipolar patientsRene L Olvera
Division of Child and Adolescent Psychiatry, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas
J Child Adolesc Psychopharmacol 17:461-73. 2007.... - Abnormal cellular energy and phospholipid metabolism in the left dorsolateral prefrontal cortex of medication-free individuals with bipolar disorder: an in vivo 1H MRS studyBenicio N Frey
MOOD CNS Program, Division of Mood and Anxiety Disorders, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, TX 78229, USA
Bipolar Disord 9:119-27. 2007..We hypothesized that BD subjects would present abnormal cellular metabolism within the DLPFC, as reflected by lower N-acetyl-aspartate (NAA) and creatine + phosphocreatine (Cr + PCr)... - Reduced NAA levels in the dorsolateral prefrontal cortex of young bipolar patientsRoberto B Sassi
Division of Mood and Anxiety Disorders, Associate Professor of Psychiatry and Radiology, Krus Endowed Chair in Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229-3900, USA
Am J Psychiatry 162:2109-15. 2005..These neuronal abnormalities in the dorsolateral prefrontal cortex of bipolar disorder youth are unlikely to represent long-term degenerative processes, at least in the subgroup of patients where the illness had relatively early onset... - Proton spectroscopy study of the left dorsolateral prefrontal cortex in pediatric depressed patientsSheila C Caetano
Division of Mood and Anxiety Disorders, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA
Neurosci Lett 384:321-6. 2005..Increased myo-inositol levels in MDD may represent a disturbed secondary messenger system. GPC + PC and myo-inositol abnormalities further demonstrate the involvement of DLPFC in pediatric MDD... - 1H magnetic resonance spectroscopy investigation of the dorsolateral prefrontal cortex in bipolar disorder patientsPaolo Brambilla
Division of Mood and Anxiety Disorders, Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
J Affect Disord 86:61-7. 2005..Longitudinal 1H MRS studies should further examine NAA levels in prefrontal cortex regions in untreated bipolar patients before and after mood stabilizing treatment... - 1H Magnetic resonance spectroscopy study of dorsolateral prefrontal cortex in unipolar mood disorder patientsPaolo Brambilla
Department of Psychiatry, Division of Mood and Anxiety Disorders, University of Texas Health Sciences Center at San Antonio, San Antonio, TX, USA
Psychiatry Res 138:131-9. 2005..Future 1H MRS investigations should longitudinally examine the role of illness chronicity on DLPFC abnormalities and their relationship with the symptoms of unipolar disorder... - A proton magnetic resonance spectroscopy investigation of the dorsolateral prefrontal cortex in acute maniaBenicio N Frey
Laboratorio de PsiquiatrÃa Experimental, Hospital de Clinicas de Porto Alegre, Porto Alegre, Brasil
Hum Psychopharmacol 20:133-9. 2005..N-acetyl-L-aspartate (NAA), choline-containing molecules (Cho), creatine plus phosphocreatine (Cr) and myoinositol (Ino) were measured... - Correlations between peripheral polyunsaturated fatty acid content and in vivo membrane phospholipid metabolitesJeffrey K Yao
Neurochemistry and Psychopharmacology Laboratory, VA Pittsburgh Healthcare System, Building 13, 7180 Highland Drive, Pittsburgh, PA 15206, USA
Biol Psychiatry 52:823-30. 2002.... - 31P-MRS study of acetyl-L-carnitine treatment in geriatric depression: preliminary resultsJay W Pettegrew
Neurophysics Laboratory, Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
Bipolar Disord 4:61-6. 2002.... - In vivo magnetic resonance spectroscopy and its application to neuropsychiatric disordersJeffrey A Stanley
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Can J Psychiatry 47:315-26. 2002..These findings are consistent with developmental alterations in the temporal lobe and in the cerebellum of persons with autism. This paper discusses recent findings of new functions of N-acetylaspartate...
Research Grants
- In Vivo 31P Spectroscopy and MRI in ADHDJEFFREY STANLEY; Fiscal Year: 2005..While one would not expect new treatments to emerge directly from this study's findings, the increased molecular/biochemical knowledge of ADHD will anchor future efforts to develop specific somatic treatments for ADHD. ..
- Assessing Development Trajectories of the Brain Biochemistry in ADHD at 4 TeslaJeffrey A Stanley; Fiscal Year: 2010....
- Assessing Development Trajectories of the Brain Biochemistry in ADHD at 4 TeslaJeffrey A Stanley; Fiscal Year: 2010....