Anne M Skoff
Affiliation: Wayne State University
- Nerve growth factor regulates substance P in adult sensory neurons through both TrkA and p75 receptorsAnne M Skoff
Department of Neurology, Wayne State University School of Medicine, 8D University Health Center, 4201 St Antoine, Detroit, MI 48201, USA
Exp Neurol 197:430-6. 2006..Our data suggest that NGF up-regulation of SP expression requires the involvement of both TrkA and p75, although the specific contribution of each receptor to SP signaling remains to be determined...
- Interleukin-1alpha regulates substance P expression and release in adult sensory neuronsAnne M Skoff
Wayne State University School of Medicine, USA
Exp Neurol 217:395-400. 2009..In summary, IL-1alpha was significantly more efficient than IL-1beta at up-regulating SP expression than IL-1beta. Taken together, these observations suggest an important role for IL-1alpha in the events following nerve injury...
- Nerve growth factor (NGF) and glial cell line-derived neurotrophic factor (GDNF) regulate substance P release in adult spinal sensory neuronsAnne M Skoff
Department of Neurology, Wayne State University School of Medicine, 4201 St Antoine, Detroit, Michigan 48201, USA
Neurochem Res 28:847-54. 2003..It appears therefore that NGF increases SP release indirectly by increasing intracellular stores...
- Partial sciatic nerve transection causes redistribution of pain-related peptides and lowers withdrawal thresholdMuthulekha Swamydas
Department of Neurology, Wayne State University School of Medicine, Detroit, MI 48201, USA
Exp Neurol 188:444-51. 2004..The presence of increased levels of nociceptive peptides in regions of the spinal cord that mediate innocuous sensation may underlie development of allodynia...
- Modulation of neuropathic pain by a glial-derived factorJoshua E Adler
Department of Neurology, John Dingell Veterans Administration Medical Center, Detroit, MI 48201, USA
Pain Med 10:1229-36. 2009..Although most cytokines are pronociceptive, one, glial cell line-derived neurotrophic factor (GDNF), appears to be antinociceptive...