Seetha Shankaran

Summary

Affiliation: Wayne State University
Country: USA

Publications

  1. ncbi request reprint Neurodevelopmental outcome of premature infants after antenatal phenobarbital exposure
    Seetha Shankaran
    Wayne State University, Detroit, MI, USA
    Am J Obstet Gynecol 187:171-7. 2002
  2. ncbi request reprint Whole-body hypothermia for neonatal encephalopathy: animal observations as a basis for a randomized, controlled pilot study in term infants
    Seetha Shankaran
    Wayne State University, Detroit, Michigan, USA
    Pediatrics 110:377-85. 2002
  3. pmc Effect of inborn vs. outborn delivery on neurodevelopmental outcomes in infants with hypoxic-ischemic encephalopathy: secondary analyses of the NICHD whole-body cooling trial
    Girija Natarajan
    Department of Pediatrics, Wayne State University, Detroit, Michigan, USA
    Pediatr Res 72:414-9. 2012
  4. pmc Predictive value of an early amplitude integrated electroencephalogram and neurologic examination
    Seetha Shankaran
    Department of Pediatrics, Wayne State University, Detroit, Michigan, USA
    Pediatrics 128:e112-20. 2011
  5. doi request reprint Outcomes of small for gestational age infants born at <27 weeks' gestation
    Lilia C De Jesus
    Department of Pediatrics, Wayne State University, Detroit, MI, USA
    J Pediatr 163:55-60.e1-3. 2013
  6. pmc Evolution of encephalopathy during whole body hypothermia for neonatal hypoxic-ischemic encephalopathy
    Seetha Shankaran
    Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI, USA
    J Pediatr 160:567-572.e3. 2012
  7. pmc Temperature profile and outcomes of neonates undergoing whole body hypothermia for neonatal hypoxic-ischemic encephalopathy
    Seetha Shankaran
    Wayne State University School of Medicine, Detroit, MI, USA
    Pediatr Crit Care Med 13:53-9. 2012
  8. pmc Hypocarbia and adverse outcome in neonatal hypoxic-ischemic encephalopathy
    Athina Pappas
    Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI 48201, USA
    J Pediatr 158:752-758.e1. 2011
  9. pmc Association between blood spot transforming growth factor-β and patent ductus arteriosus in extremely low-birth weight infants
    Girija Natarajan
    Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Pediatr Cardiol 34:149-54. 2013
  10. ncbi request reprint Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy
    Seetha Shankaran
    Division of Neonatal Perinatal Medicine, Wayne State University, Children s Hospital of Michigan, Detroit, MI 48201, USA
    N Engl J Med 353:1574-84. 2005

Detail Information

Publications80

  1. ncbi request reprint Neurodevelopmental outcome of premature infants after antenatal phenobarbital exposure
    Seetha Shankaran
    Wayne State University, Detroit, MI, USA
    Am J Obstet Gynecol 187:171-7. 2002
    ....
  2. ncbi request reprint Whole-body hypothermia for neonatal encephalopathy: animal observations as a basis for a randomized, controlled pilot study in term infants
    Seetha Shankaran
    Wayne State University, Detroit, Michigan, USA
    Pediatrics 110:377-85. 2002
    ....
  3. pmc Effect of inborn vs. outborn delivery on neurodevelopmental outcomes in infants with hypoxic-ischemic encephalopathy: secondary analyses of the NICHD whole-body cooling trial
    Girija Natarajan
    Department of Pediatrics, Wayne State University, Detroit, Michigan, USA
    Pediatr Res 72:414-9. 2012
    ..5 °C for 72 h in term infants (n = 208) with hypoxic-ischemic encephalopathy (HIE) who participated in the Neonatal Research Network (NRN) randomized controlled trial...
  4. pmc Predictive value of an early amplitude integrated electroencephalogram and neurologic examination
    Seetha Shankaran
    Department of Pediatrics, Wayne State University, Detroit, Michigan, USA
    Pediatrics 128:e112-20. 2011
    ..To examine the predictive validity of the amplitude integrated electroencephalogram (aEEG) and stage of encephalopathy among infants with hypoxic-ischemic encephalopathy (HIE) eligible for therapeutic whole-body hypothermia...
  5. doi request reprint Outcomes of small for gestational age infants born at <27 weeks' gestation
    Lilia C De Jesus
    Department of Pediatrics, Wayne State University, Detroit, MI, USA
    J Pediatr 163:55-60.e1-3. 2013
    ..To determine whether small for gestational age (SGA) infants born at <27 weeks gestational age (GA) are at increased risk for mortality, morbidity, and growth and neurodevelopmental impairment at 18-22 months corrected age...
  6. pmc Evolution of encephalopathy during whole body hypothermia for neonatal hypoxic-ischemic encephalopathy
    Seetha Shankaran
    Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI, USA
    J Pediatr 160:567-572.e3. 2012
    ..To examine the predictive ability of stage of hypoxic-ischemic encephalopathy (HIE) for death or moderate/severe disability at 18 months among neonates undergoing hypothermia...
  7. pmc Temperature profile and outcomes of neonates undergoing whole body hypothermia for neonatal hypoxic-ischemic encephalopathy
    Seetha Shankaran
    Wayne State University School of Medicine, Detroit, MI, USA
    Pediatr Crit Care Med 13:53-9. 2012
    ....
  8. pmc Hypocarbia and adverse outcome in neonatal hypoxic-ischemic encephalopathy
    Athina Pappas
    Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI 48201, USA
    J Pediatr 158:752-758.e1. 2011
    ..To evaluate the association between early hypocarbia and 18- to 22-month outcome among neonates with hypoxic-ischemic encephalopathy...
  9. pmc Association between blood spot transforming growth factor-β and patent ductus arteriosus in extremely low-birth weight infants
    Girija Natarajan
    Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Pediatr Cardiol 34:149-54. 2013
    ..83-1.17; day 7 OR 0.88, 95 % CI 0.74-1.04) on adjusted analyses. Our results suggest that blood spot TGF-β alone is unlikely to be a reliable biomarker of a clinically significant PDA or its responsiveness to treatment...
  10. ncbi request reprint Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy
    Seetha Shankaran
    Division of Neonatal Perinatal Medicine, Wayne State University, Children s Hospital of Michigan, Detroit, MI 48201, USA
    N Engl J Med 353:1574-84. 2005
    ..Hypothermia is protective against brain injury after asphyxiation in animal models. However, the safety and effectiveness of hypothermia in term infants with encephalopathy is uncertain...
  11. pmc Outcome of extremely preterm infants (<1,000 g) with congenital heart defects from the National Institute of Child Health and Human Development Neonatal Research Network
    Athina Pappas
    Department of Pediatrics, Children s Hospital of Michigan and Hutzel Women s Hospital, Wayne State University, 3901 Beaubien, Detroit, MI 48201, USA
    Pediatr Cardiol 33:1415-26. 2012
    ..38 %, p = 0.004). Risk of death or NDI was greater for ELBW infants with CHD, although 20 % of infants survived without NDI...
  12. pmc Brain injury following trial of hypothermia for neonatal hypoxic-ischaemic encephalopathy
    Seetha Shankaran
    Department of Pediatrics Neonatology, Children s Hospital of Michigan, 3901 Beaubien Blvd, Detroit, MI 48201, USA
    Arch Dis Child Fetal Neonatal Ed 97:F398-404. 2012
    ..The objective of our study was to examine the relationship between brain injury and outcome following neonatal hypoxic-ischaemic encephalopathy treated with hypothermia...
  13. pmc Prenatal cocaine exposure and BMI and blood pressure at 9 years of age
    Seetha Shankaran
    Wayne State University School of Medicine, Detroit, Michigan, USA
    J Hypertens 28:1166-75. 2010
    ....
  14. ncbi request reprint Outcome of extremely-low-birth-weight infants at highest risk: gestational age < or =24 weeks, birth weight < or =750 g, and 1-minute Apgar < or =3
    Seetha Shankaran
    Wayne State University, Detroit, MI, USA
    Am J Obstet Gynecol 191:1084-91. 2004
    ....
  15. pmc Outcomes of safety and effectiveness in a multicenter randomized, controlled trial of whole-body hypothermia for neonatal hypoxic-ischemic encephalopathy
    Seetha Shankaran
    Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan, USA
    Pediatrics 122:e791-8. 2008
    ..Whole-body hypothermia reduced the frequency of death or moderate/severe disabilities in neonates with hypoxic-ischemic encephalopathy in a randomized, controlled multicenter trial...
  16. ncbi request reprint Risk factors for early death among extremely low-birth-weight infants
    Seetha Shankaran
    Wayne State University, Detroit, Michigan, USA
    Am J Obstet Gynecol 186:796-802. 2002
    ....
  17. pmc Risk factors for post-neonatal intensive care unit discharge mortality among extremely low birth weight infants
    Lilia C De Jesus
    Department of Pediatrics, Wayne State University, Detroit, MI, USA
    J Pediatr 161:70-4.e1-2. 2012
    ..The study goal was to evaluate maternal and neonatal risk factors associated with post-neonatal intensive care unit (NICU) discharge mortality among extremely low birth weight (ELBW) infants...
  18. pmc Impact of maternal substance use during pregnancy on childhood outcome
    Seetha Shankaran
    Wayne State University School of Medicine, Detroit, MI, USA
    Semin Fetal Neonatal Med 12:143-50. 2007
    ..Therefore, efforts should be made to prevent and treat behavioral problems as well as to limit the onset of drug use by adolescent children born to women who use drugs during pregnancy...
  19. ncbi request reprint Association between patterns of maternal substance use and infant birth weight, length, and head circumference
    Seetha Shankaran
    Wayne State University, Detroit, Michigan, USA
    Pediatrics 114:e226-34. 2004
    ..To determine the effects of patterns of drug use during term pregnancy on infant growth parameters at birth...
  20. pmc Circulating beta chemokine and MMP 9 as markers of oxidative injury in extremely low birth weight infants
    Girija Natarajan
    Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    Pediatr Res 67:77-82. 2010
    ..003). The consistent association between O2 exposure and MCP 1 among extremely preterm infants suggests that further investigation of its role in oxidative injury is warranted...
  21. pmc Outcomes of extremely low birth weight infants with bronchopulmonary dysplasia: impact of the physiologic definition
    Girija Natarajan
    Department of Pediatrics, Wayne State University, Detroit, MI, USA
    Early Hum Dev 88:509-15. 2012
    ..We compared neurodevelopmental outcomes of extremely low birth weight (ELBW) infants with and without bronchopulmonary dysplasia (BPD), using the physiologic definition...
  22. pmc Childhood outcomes after hypothermia for neonatal encephalopathy
    Seetha Shankaran
    Department of Pediatrics, Wayne State University, Detroit, MI, USA
    N Engl J Med 366:2085-92. 2012
    ..Long-term outcomes are now available...
  23. ncbi request reprint Challenge of conducting trials of neuroprotection in the asphyxiated term infant
    Seetha Shankaran
    Department of Pediatrics, Wayne State University, Detroit, MI, USA
    Semin Perinatol 27:320-32. 2003
    ..Since clinical trials of brain hypothermia are in progress, many of these issues will be addressed from the perspective of this specific intervention...
  24. pmc Cytokine profiles of preterm neonates with fungal and bacterial sepsis
    Beena G Sood
    Department of Pediatrics, Wayne State University, Detroit, Michigan, USA
    Pediatr Res 72:212-20. 2012
    ..We hypothesized that cytokine profiles in the first 21 d of life in ELBW infants with FS differ from those with bacterial sepsis (BS) or no sepsis (NS)...
  25. doi request reprint Prevention, diagnosis, and treatment of cerebral palsy in near-term and term infants
    Seetha Shankaran
    Children s Hospital of Michigan, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    Clin Obstet Gynecol 51:829-39. 2008
    ..Treatment of CP based on evidenced-based data will be reviewed...
  26. pmc Neonatal encephalopathy: treatment with hypothermia
    Seetha Shankaran
    Department of Pediatrics, Wayne State University School of Medicine, Division of Neonatal Perinatal Medicine, Children s Hospital of Michigan, Detroit, Michigan 48201, USA
    J Neurotrauma 26:437-43. 2009
    ..Lastly, the status of ongoing neonatal hypothermia trials will be summarized...
  27. pmc Validation of the Functional Status II questionnaire in the assessment of extremely-low-birthweight infants
    David Da Costa
    Department of Pediatrics, William Beaumont Hospital, Royal Oak, MI, USA
    Dev Med Child Neurol 51:536-44. 2009
    ..The revised Functional Status questionnaire (FS-II) was designed to assess caregivers' perceptions of the functional status of children with chronic diseases...
  28. ncbi request reprint Health-care utilization among mothers and infants following cocaine exposure
    Seetha Shankaran
    Wayne State University, Detroit, MI, USA
    J Perinatol 23:361-7. 2003
    ..To examine utilization of health-care resources among mothers and infants following cocaine use during pregnancy...
  29. ncbi request reprint Hypothermia as a treatment for birth asphyxia
    Seetha Shankaran
    Wayne State University, Children s Hospital of Michigan, Detroit, MI 48201, USA
    Clin Obstet Gynecol 50:624-35. 2007
    ..The evidence-based trials of hypothermia will be reviewed along with recommendations regarding clinical applications for this therapy and need for long-term follow-up of children receiving this therapy...
  30. ncbi request reprint Changes in amplitude-integrated electroencephalography in neonates treated with extracorporeal membrane oxygenation: a pilot study
    Athina Pappas
    Neonatal Perinatal Medicine Department, Wayne State University School of Medicine, Detroit, Michigan, USA
    J Pediatr 148:125-7. 2006
    ..An abnormal aEEG predicted death or moderate to severe intracranial neuropathology with sensitivity = 1.0, specificity = 0.75, positive predictive value = 0.86, and negative predictive value = 1.0...
  31. ncbi request reprint Fetal origin of childhood disease: intrauterine growth restriction in term infants and risk for hypertension at 6 years of age
    Seetha Shankaran
    National Institute of Child Health and Human Development Neonatal Research Network, Bethesda, MD, USA
    Arch Pediatr Adolesc Med 160:977-81. 2006
    ..To examine the association between intrauterine growth restriction (IUGR) status at birth among full-term infants, exposure to substance use during pregnancy, and risk of hypertension at 6 years of age...
  32. pmc Aerosolized PGE1: a selective pulmonary vasodilator in neonatal hypoxemic respiratory failure results of a Phase I/II open label clinical trial
    Beena G Sood
    Department of Pediatrics, Wayne State University, Children s Hospital of Michigan, 3901 Beaubien Boulevard, Detroit, MI 48201 USA
    Pediatr Res 56:579-85. 2004
    ..The results of our study indicate that IPGE(1) may be a safe, selective pulmonary vasodilator in neonatal hypoxemic respiratory failure...
  33. ncbi request reprint Age of smoking onset as a predictor of smoking cessation during pregnancy
    Xinguang Chen
    Prevention Research Center, The Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, 4201 St Antoine Street, Detroit, MI 48201, USA
    Am J Health Behav 30:247-58. 2006
    ..To assess age of smoking onset as a predictor of smoking cessation during pregnancy...
  34. ncbi request reprint The postnatal management of the asphyxiated term infant
    Seetha Shankaran
    Neonatal Perinatal Medicine, Wayne State University School of Medicine, 3901 Beaubien Blvd, Detroit, MI 48201, USA
    Clin Perinatol 29:675-92. 2002
    ....
  35. pmc A randomized placebo-controlled trial of massage therapy on the immune system of preterm infants
    Jocelyn Y Ang
    Division of Infectious Diseases, Carman and Ann Adams Department of Pediatrics, Children s Hospital of Michigan, Detroit, MI 48201, USA
    Pediatrics 130:e1549-58. 2012
    ..The primary hypothesis was that MT compared with sham therapy (control) will enhance the immune system of stable premature infants by increasing the proportion of their natural killer (NK) cell numbers...
  36. ncbi request reprint Cumulative index of exposure to hypocarbia and hyperoxia as risk factors for periventricular leukomalacia in low birth weight infants
    Seetha Shankaran
    Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan, USA
    Pediatrics 118:1654-9. 2006
    ..Hypocarbia and hyperoxia are risk factors for periventricular leukomalacia in low birth weight infants. The association of a cumulative index of exposure to hypocarbia and hyperoxia and periventricular leukomalacia has not been evaluated...
  37. pmc Perinatal systemic inflammatory response syndrome and retinopathy of prematurity
    Beena G Sood
    Department of Pediatrics, Wayne State University, Detroit, Michigan 48201, USA
    Pediatr Res 67:394-400. 2010
    ..We conclude that perinatal inflammation may be involved in the pathogenesis of ROP...
  38. doi request reprint Parental perception of functional status following tracheostomy in infancy: a single center study
    Sharayu Rane
    Division of Neonatal Perinatal Medicine, Department of Pediatrics, Children s Hospital of Michigan, Wayne State University, Detroit, MI
    J Pediatr 163:860-6. 2013
    ..To examine the functional outcomes of children who underwent a tracheostomy in the initial hospitalization after birth and to determine their correlates...
  39. ncbi request reprint Systemic levels following PGE1 inhalation in neonatal hypoxemic respiratory failure
    Beena G Sood
    Carman and Ann Adams Department of Pediatrics, Wayne State University, Hutzel Women s Hospital and Children s Hospital of Michigan, Detroit, MI 48201, USA
    Acta Paediatr 95:1093-8. 2006
    ..To measure plasma prostaglandin E1 (PGE1) levels in newborns with hypoxemic respiratory failure (NHRF) following inhaled PGE1 (IPGE1), normal term newborns, and newborns with congenital heart disease (CHD) following intravenous PGE1...
  40. ncbi request reprint Role of plasma B-type natriuretic peptide in screening for hemodynamically significant patent ductus arteriosus in preterm neonates
    Sanjeev Sanjeev
    Division of Pediatric Cardiology, Children s Hosptial of Michigan, Detroit, MI 48201, USA
    J Perinatol 25:709-13. 2005
    ..B-type natriuretic peptide (BNP) is a hormone secreted by the ventricles under hemodynamic stress and congestive failure...
  41. ncbi request reprint Transient hypermetabolism of the basal ganglia following perinatal hypoxia
    Carlos E A Batista
    Carman and Ann Adams, Department of Pediatrics, Children s Hospital of Michigan, Wayne State University, Detroit, Michigan 48201, USA
    Pediatr Neurol 36:330-3. 2007
    ..Thus, positron emission tomography can help predict this form of cerebral palsy in neonates...
  42. pmc Neurodevelopmental outcome of extremely low birth weight infants with posthemorrhagic hydrocephalus requiring shunt insertion
    Ira Adams-Chapman
    Department of Pediatrics Division of Neonatology, Emory University School of Medicine, 46 Jesse Hill Jr Drive SE, Atlanta, GA 30303, USA
    Pediatrics 121:e1167-77. 2008
    ..We aimed to evaluate neurodevelopmental and growth outcomes among extremely low birth weight infants who had severe intraventricular hemorrhage that required shunt insertion compared with infants without shunt insertion...
  43. pmc Association between urinary lactate to creatinine ratio and neurodevelopmental outcome in term infants with hypoxic-ischemic encephalopathy
    William Oh
    Department of Pediatrics, Warren Alpert Medical School of Brown University, Providence, RI, USA
    J Pediatr 153:375-8. 2008
    ..To assess the association between urinary lactate to creatinine ratio (ULCR) and neurodevelopmental outcome in term infants with hypoxic ischemic encephalopathy and examine the effect of hypothermia on the change in ULCR...
  44. pmc Effects of prenatal cocaine exposure on special education in school-aged children
    Todd P Levine
    Department of Pediatrics, Warren Alpert Medical School, Brown University, Providence, Rhode Island 02905, USA
    Pediatrics 122:e83-91. 2008
    ..The objective of this study was to evaluate the effects of prenatal cocaine exposure on special education at age 7 with adjustment for covariates...
  45. doi request reprint Therapeutic hypothermia in neonates. Review of current clinical data, ILCOR recommendations and suggestions for implementation in neonatal intensive care units
    Thomas Hoehn
    Neonatology and Pediatric Intensive Care Medicine, Department of General Pediatrics, Heinrich Heine University, Duesseldorf, Germany
    Resuscitation 78:7-12. 2008
    ....
  46. pmc Community supports after surviving extremely low-birth-weight, extremely preterm birth: special outpatient services in early childhood
    Susan R Hintz
    Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California 94304, USA
    Arch Pediatr Adolesc Med 162:748-55. 2008
    ..To determine special outpatient services (SOS) use, need, associated factors, and neurodevelopmental and functional outcomes among extremely preterm infants at 18 to 22 months' corrected age...
  47. pmc Very low birth weight preterm infants with surgical short bowel syndrome: incidence, morbidity and mortality, and growth outcomes at 18 to 22 months
    Conrad R Cole
    Emory University School of Medicine, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, 2015 Uppergate Dr, Atlanta, GA 30322, USA
    Pediatrics 122:e573-82. 2008
    ....
  48. pmc Elevated temperature after hypoxic-ischemic encephalopathy: risk factor for adverse outcomes
    Abbot Laptook
    Department of Pediatrics, Women and Infants Hospital of Rhode Island, 101 Dudley St, Providence, RI 02906, USA
    Pediatrics 122:491-9. 2008
    ....
  49. doi request reprint Importance of stability of early living arrangements on behavior outcomes of children with and without prenatal drug exposure
    Henrietta S Bada
    Department of Pediatrics, University of Kentucky College of Medicine, Lexington, Kentucky 40536, USA
    J Dev Behav Pediatr 29:173-82. 2008
    ..We evaluated whether living arrangements of children with or without prenatal drug exposure would be associated with their behavior outcomes and adaptive functioning...
  50. ncbi request reprint Adverse neurodevelopmental outcomes among extremely low birth weight infants with a normal head ultrasound: prevalence and antecedents
    Abbot R Laptook
    Brown Medical School, Providence, Rhode Island, USA
    Pediatrics 115:673-80. 2005
    ..This study examined the prevalence of and risk factors for CP and impaired mental development among ELBW infants with a normal HUS...
  51. ncbi request reprint Low birth weight and preterm births: etiologic fraction attributable to prenatal drug exposure
    Henrietta S Bada
    Department of Pediatrics, College of Medicine and College of Public Health, University of Kentucky, Lexington, KY 40536, USA
    J Perinatol 25:631-7. 2005
    ..To determine the factors that would increase the likelihood of outcomes: low birth weight (LBW), preterm births and intrauterine growth restriction (IUGR)...
  52. ncbi request reprint Inhaled nitric oxide for premature infants with severe respiratory failure
    Krisa P Van Meurs
    Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, Calif 94304, USA
    N Engl J Med 353:13-22. 2005
    ..We conducted a multicenter, randomized, blinded, controlled trial to determine whether inhaled nitric oxide reduced the rate of death or bronchopulmonary dysplasia in such infants...
  53. ncbi request reprint Interactions between maternal characteristics and neonatal behavior in the prediction of parenting stress and perception of infant temperament
    Stephen J Sheinkopf
    Brown Medical School, Bradley Hospital, 1011 Veterans Memorial Parkway, East Providence, Rhode Island 02915, USA
    J Pediatr Psychol 31:27-40. 2006
    ..Prenatal cocaine exposure is a marker of developmental risk. Social environmental risk factors may include maternal stress and maternal perceptions of difficult infant temperament...
  54. ncbi request reprint The maternal lifestyle study: effects of substance exposure during pregnancy on neurodevelopmental outcome in 1-month-old infants
    Barry M Lester
    Brown Medical School, Infant Development Center, Women and Infant s Hospital and Bradley Hospital, Providence, Rhode Island 02905 2499, USA
    Pediatrics 110:1182-92. 2002
    ..This was a prospective longitudinal multisite study of the effects of prenatal cocaine and/or opiate exposure on neurodevelopmental outcome in term and preterm infants at 1 month of age...
  55. ncbi request reprint Predictors of motor development in children prenatally exposed to cocaine
    Cynthia Miller-Loncar
    Brown Medical School, Women and Infants Hospital, Providence, RI 02903, United States
    Neurotoxicol Teratol 27:213-20. 2005
    ..Heavy cocaine use related to poorer motor performance as compared to no use, but there were no effects of level of cocaine use on change in motor skills...
  56. ncbi request reprint The Maternal Lifestyle Study (MLS): effects of prenatal cocaine and/or opiate exposure on auditory brain response at one month
    Barry M Lester
    Brown Medical School, the Infant Development Center, Women and Infant s Hospital, and Bradley Hospital, Providence, Rhode Island 02905 2499, USA
    J Pediatr 142:279-85. 2003
    ..Exposure was determined by meconium assay and self-report with alcohol, marijuana, and tobacco present in both groups. At 1 month, infants were tested by masked examiners with the auditory brain response...
  57. ncbi request reprint The maternal lifestyle study: cognitive, motor, and behavioral outcomes of cocaine-exposed and opiate-exposed infants through three years of age
    Daniel S Messinger
    Department of Psychology, University of Miami, Coral Gables, Florida, USA
    Pediatrics 113:1677-85. 2004
    ..To evaluate the direct effects of prenatal cocaine exposure and prenatal opiate exposure on infant mental, motor, and behavioral outcomes longitudinally between 1 and 3 years old...
  58. ncbi request reprint Attachment status in children prenatally exposed to cocaine and other substances
    Ronald Seifer
    Medical School, Brown University, Providence, RI 02915, USA
    Child Dev 75:850-68. 2004
    ..Attachment status at 18 months was associated with child temperament and caregiver-child interaction; at 36 months, attachment was associated with child temperament, child behavior problems, and caregivers' parenting self-esteem...
  59. ncbi request reprint Association between peak serum bilirubin and neurodevelopmental outcomes in extremely low birth weight infants
    William Oh
    Women and Infants Hospital of Rhode Island Brown University, Providence, Rhode Island 02905, USA
    Pediatrics 112:773-9. 2003
    ..To assess the association between peak total serum bilirubin (PSB) levels during the first 2 weeks of life and neurodevelopmental outcomes of extremely low birth weight (ELBW) infants at 18 to 22 months' postmenstrual age...
  60. ncbi request reprint Acute neonatal effects of cocaine exposure during pregnancy
    Charles R Bauer
    Department of Pediatrics, University of Miami School of Medicine, Miami, FL 33101, USA
    Arch Pediatr Adolesc Med 159:824-34. 2005
    ..To identify associations between cocaine exposure during pregnancy and medical conditions in newborn infants from birth through hospital discharge...
  61. ncbi request reprint Hypothermia and perinatal asphyxia: executive summary of the National Institute of Child Health and Human Development workshop
    Rosemary D Higgins
    Pregnancy and Perinatology Branch, Center for Developmental Biology and Perinatal Medicine, National Institute of Child Health and Human Development NIH, 6100 Executive Boulevard, MSC 7510, Bethesda, MD 20892, USA
    J Pediatr 148:170-175. 2006
  62. doi request reprint Hypothermia: an evolving treatment for neonatal hypoxic ischemic encephalopathy
    Alistair J Gunn
    Pediatrics 121:648-9; author reply 649-50. 2008
  63. ncbi request reprint Vagal tone as a resilience factor in children with prenatal cocaine exposure
    Stephen J Sheinkopf
    The Warren Alpert Medical School of Brown, Rhode Island, USA
    Dev Psychopathol 19:649-73. 2007
    ..This is consistent with theory linking reduced VT during tasks to adaptive regulation and indicates that such regulatory functioning may serve as a protective factor in prenatal CE...
  64. ncbi request reprint Trends in neonatal morbidity and mortality for very low birthweight infants
    Avroy A Fanaroff
    Department of Pediatrics, Case Western Reserve University, Cleveland, OH
    Am J Obstet Gynecol 196:147.e1-8. 2007
    ..To document the mortality and morbidity of infants weighing 501-1500 g at birth according to gestational age, birthweight, and sex...
  65. ncbi request reprint Impact of prenatal cocaine exposure on child behavior problems through school age
    Henrietta S Bada
    Department of Pediatrics, University of Kentucky College of Medicine, Lexington, Kentucky, USA
    Pediatrics 119:e348-59. 2007
    ..We examined the trajectory of childhood behavior problems after prenatal cocaine exposure...
  66. pmc Prenatal cocaine use and maternal depression: effects on infant neurobehavior
    Amy L Salisbury
    Brown Medical School, Providence, RI, USA
    Neurotoxicol Teratol 29:331-40. 2007
    ..The present study examined the impact of both perinatal maternal depression and cocaine use on infant neurobehavior at 1 month of age in a large, multi-site study...
  67. ncbi request reprint Predicting outcomes of neonates diagnosed with hypoxemic-ischemic encephalopathy
    Namasivayam Ambalavanan
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    Pediatrics 118:2084-93. 2006
    ..The goals were to identify predictor variables and to develop scoring systems and classification trees to predict death/disability or death in infants with hypoxic-ischemic encephalopathy...
  68. ncbi request reprint Gestational cocaine exposure and intrauterine growth: maternal lifestyle study
    Henrietta S Bada
    The University of Kentucky, Lexington, Kentucky 40536, USA
    Obstet Gynecol 100:916-24. 2002
    ..To estimate the effects of cocaine exposure on intrauterine growth and to investigate at what point in gestation growth deviation would be manifested...
  69. ncbi request reprint Summary statistics of neonatal intensive care unit network neurobehavioral scale scores from the maternal lifestyle study: a quasinormative sample
    Barry M Lester
    Brown Medical School, Infant Development Center, Women and Infants Hospital and Bradley Hospital, Providence, Rhode Island 02903, USA
    Pediatrics 113:668-75. 2004
    ..These tables can be used as quasinorms for comparison with other infants of this age...
  70. ncbi request reprint Minimal ventilation to prevent bronchopulmonary dysplasia in extremely-low-birth-weight infants
    Waldemar A Carlo
    University of Alabama at Birmingham, Division of Neonatology, 35233, USA
    J Pediatr 141:370-4. 2002
    ..The primary outcome was death or BPD at 36 weeks' postmenstrual age...
  71. ncbi request reprint Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network
    Barbara J Stoll
    Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Pediatrics 110:285-91. 2002
    ....
  72. ncbi request reprint To tap or not to tap: high likelihood of meningitis without sepsis among very low birth weight infants
    Barbara J Stoll
    Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA
    Pediatrics 113:1181-6. 2004
    ..We speculated that meningitis may be underdiagnosed among very low birth weight (VLBW) infants because of the failure to perform lumbar punctures (LPs) in infants with suspected sepsis...
  73. ncbi request reprint Parenteral glutamine supplementation does not reduce the risk of mortality or late-onset sepsis in extremely low birth weight infants
    Brenda B Poindexter
    Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Pediatrics 113:1209-15. 2004
    ..Whether glutamine supplementation would provide a similar benefit to extremely low birth weight (ELBW) infants is not known...
  74. ncbi request reprint Effect of parenteral glutamine supplementation on plasma amino acid concentrations in extremely low-birth-weight infants
    Brenda B Poindexter
    Indiana University, Indianapolis, USA
    Am J Clin Nutr 77:737-43. 2003
    ..Glutamine is one of the most abundant amino acids in both plasma and human milk and may be conditionally essential in premature infants. However, glutamine is not provided by standard intravenous amino acid solutions...
  75. ncbi request reprint The Maternal Lifestyle Study: drug exposure during pregnancy and short-term maternal outcomes
    Charles R Bauer
    Department of Pediatrics, University of Miami School of Medicine, Fla 33101, USA
    Am J Obstet Gynecol 186:487-95. 2002
    ..The Maternal Lifestyle Study (MLS) is a multicenter, prospective, observational study that was initiated to better define the effects of exposure to illicit drugs during pregnancy on the mother, fetus, and infant...
  76. pmc Predictors of death or bronchopulmonary dysplasia in preterm infants with respiratory failure
    N Ambalavanan
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    J Perinatol 28:420-6. 2008
    ..To identify the variables that predict death/physiologic bronchopulmonary dysplasia (BPD) in preterm infants with severe respiratory failure...
  77. pmc Aggressive vs. conservative phototherapy for infants with extremely low birth weight
    Brenda H Morris
    University of Texas Medical School, Houston, TX 77030, USA
    N Engl J Med 359:1885-96. 2008
    ..It is unclear whether aggressive phototherapy to prevent neurotoxic effects of bilirubin benefits or harms infants with extremely low birth weight (1000 g or less)...
  78. ncbi request reprint Violence and delinquency, early onset drug use, and psychopathology in drug-exposed youth at 11 years
    Linda L Lagasse
    Brown Medical School, Providence, Rhode Island, USA
    Ann N Y Acad Sci 1094:313-8. 2006
    ..This study provides new evidence for the impact of violence as well as resilience against disruptive forms of psychopathology and behavior...
  79. ncbi request reprint Prenatal cocaine exposure: cardiorespiratory function and resilience
    Stephen J Sheinkopf
    Brown Medical School, Providence, Rhode Island, USA
    Ann N Y Acad Sci 1094:354-8. 2006
    ..For high-risk children, low VT was related to higher ratings of adaptive behaviors. This finding suggests that regulatory functioning, as indexed by VT, may be a protective factor in prenatal CE...
  80. ncbi request reprint Changes in pathogens causing early-onset sepsis in very-low-birth-weight infants
    Barbara J Stoll
    Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA
    N Engl J Med 347:240-7. 2002
    ....