Marie P Piechocki

Summary

Affiliation: Wayne State University
Country: USA

Publications

  1. ncbi request reprint Quantitative measurement of anti-ErbB-2 antibody by flow cytometry and ELISA
    Marie P Piechocki
    Karmanos Cancer Institute, School of Medicine, Wayne State University, 429B Prentis Building, 110 E Warren Avenue, Detroit, MI 48201, USA
    J Immunol Methods 259:33-42. 2002
  2. pmc Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial
    Håkan Norell
    Department of Oncology and Pathology, Cancer Center Karolinska, Karolinska Institutet, Stockholm, Sweden
    J Transl Med 8:53. 2010
  3. ncbi request reprint Iressa induces cytostasis and augments Fas-mediated apoptosis in acinic cell adenocarcinoma overexpressing HER2/neu
    Marie P Piechocki
    Department of Otolaryngology Head and Neck Surgery, Wayne State University and Karmanos Cancer Center, Detroit, MI 48201, USA
    Int J Cancer 119:441-54. 2006
  4. ncbi request reprint Breast cancer expressing the activated HER2/neu is sensitive to gefitinib in vitro and in vivo and acquires resistance through a novel point mutation in the HER2/neu
    Marie P Piechocki
    Department of Otolaryngology Head and Neck Surgery, Wayne State University, 110 East Warren Avenue, Detroit, MI 48201, USA
    Cancer Res 67:6825-43. 2007
  5. ncbi request reprint Gefitinib prevents cancer progression in mice expressing the activated rat HER2/neu
    Marie P Piechocki
    Department of Otolaryngology Head and Neck Surgery, Wayne State University and Karmanos Cancer Center, Detroit, MI 48201, USA
    Int J Cancer 122:1722-9. 2008
  6. pmc A stable explant culture of HER2/neu invasive carcinoma supported by alpha-Smooth Muscle Actin expressing stromal cells to evaluate therapeutic agents
    Marie P Piechocki
    Department of Breast Cancer Immunotherapy, Wayne State University and Karmanos Cancer Center, Detroit, MI, USA
    BMC Cancer 8:119. 2008
  7. doi request reprint Effect of docetaxel on the surgical tumor microenvironment of head and neck cancer in murine models
    George H Yoo
    Department of Otolaryngology Head and Neck Surgery, Wayne State University, 5E University Health Center, 4201 St Antoine, Detroit, MI 48201, USA
    Arch Otolaryngol Head Neck Surg 134:735-42. 2008
  8. ncbi request reprint Docetaxel associated pathways in cisplatin resistant head and neck squamous cell carcinoma: a pilot study
    George H Yoo
    Department of Otolaryngology Head and Neck Surgery, Wayne State University and Karmanos Cancer Institute, Detroit, Michigan 48201, USA
    Laryngoscope 115:1938-46. 2005
  9. ncbi request reprint BMS-275183-induced gene expression patterns in head and neck carcinoma
    George H Yoo
    Department of Otolaryngology Head and Neck Surgery, Wayne State University and Karmanos Cancer Institute, Detroit, MI 48201, USA
    Am J Otolaryngol 28:309-15. 2007
  10. ncbi request reprint Docetaxel induced gene expression patterns in head and neck squamous cell carcinoma using cDNA microarray and PowerBlot
    George H Yoo
    Department of Otolaryngology Head and Neck Surgery, Wayne State University and Karmanos Cancer Institute, Detroit, Michigan 48201, USA
    Clin Cancer Res 8:3910-21. 2002

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Quantitative measurement of anti-ErbB-2 antibody by flow cytometry and ELISA
    Marie P Piechocki
    Karmanos Cancer Institute, School of Medicine, Wayne State University, 429B Prentis Building, 110 E Warren Avenue, Detroit, MI 48201, USA
    J Immunol Methods 259:33-42. 2002
    ..Therefore, excellent concordance in antibody concentration was obtained with different assays using linear regression and properly diluted samples. This concordance was verified with multiple serum samples...
  2. pmc Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial
    Håkan Norell
    Department of Oncology and Pathology, Cancer Center Karolinska, Karolinska Institutet, Stockholm, Sweden
    J Transl Med 8:53. 2010
    ..Here we report the first administration of a Her2-plasmid DNA (pDNA) vaccine in humans...
  3. ncbi request reprint Iressa induces cytostasis and augments Fas-mediated apoptosis in acinic cell adenocarcinoma overexpressing HER2/neu
    Marie P Piechocki
    Department of Otolaryngology Head and Neck Surgery, Wayne State University and Karmanos Cancer Center, Detroit, MI 48201, USA
    Int J Cancer 119:441-54. 2006
    ..These data showing that Iressa induces cytostasis and primes the extrinsic (Fas) and intrinsic (mitochondrial and endoplasmic reticulum) apoptotic pathways should lead to the development of novel therapeutic targets and strategies...
  4. ncbi request reprint Breast cancer expressing the activated HER2/neu is sensitive to gefitinib in vitro and in vivo and acquires resistance through a novel point mutation in the HER2/neu
    Marie P Piechocki
    Department of Otolaryngology Head and Neck Surgery, Wayne State University, 110 East Warren Avenue, Detroit, MI 48201, USA
    Cancer Res 67:6825-43. 2007
    ..This model will be useful in understanding the differences between intrinsic drug sensitivity and acquired resistance in the context of therapeutic strategies that target oncogene addicted diseases...
  5. ncbi request reprint Gefitinib prevents cancer progression in mice expressing the activated rat HER2/neu
    Marie P Piechocki
    Department of Otolaryngology Head and Neck Surgery, Wayne State University and Karmanos Cancer Center, Detroit, MI 48201, USA
    Int J Cancer 122:1722-9. 2008
    ..These studies demonstrate the critical role of HER2 signal transduction in the onset and progression of HER2/neu-dependent breast cancer and suggest a role for specific inhibitors to prevent the outgrowth of early hyperplastic disease...
  6. pmc A stable explant culture of HER2/neu invasive carcinoma supported by alpha-Smooth Muscle Actin expressing stromal cells to evaluate therapeutic agents
    Marie P Piechocki
    Department of Breast Cancer Immunotherapy, Wayne State University and Karmanos Cancer Center, Detroit, MI, USA
    BMC Cancer 8:119. 2008
    ..This co-culture, Mammary Adenocarcinoma Model (MAM-1) maintains a 1:1 ratio of HER2/neu positive tumor cells to alpha-SMA-reactive stromal cells and renews this configuration for over 20 passages in vitro...
  7. doi request reprint Effect of docetaxel on the surgical tumor microenvironment of head and neck cancer in murine models
    George H Yoo
    Department of Otolaryngology Head and Neck Surgery, Wayne State University, 5E University Health Center, 4201 St Antoine, Detroit, MI 48201, USA
    Arch Otolaryngol Head Neck Surg 134:735-42. 2008
    ..To identify the antitumor activity and wound-healing effect of docetaxel delivered in the surgical tumor microenvironment of head and neck squamous cell carcinoma (HNSCC)...
  8. ncbi request reprint Docetaxel associated pathways in cisplatin resistant head and neck squamous cell carcinoma: a pilot study
    George H Yoo
    Department of Otolaryngology Head and Neck Surgery, Wayne State University and Karmanos Cancer Institute, Detroit, Michigan 48201, USA
    Laryngoscope 115:1938-46. 2005
    ..This is a pilot study to identify changes in gene and protein expressions after treatment with docetaxel in cisplatin-resistant head and neck squamous cell carcinoma (HNSCC)...
  9. ncbi request reprint BMS-275183-induced gene expression patterns in head and neck carcinoma
    George H Yoo
    Department of Otolaryngology Head and Neck Surgery, Wayne State University and Karmanos Cancer Institute, Detroit, MI 48201, USA
    Am J Otolaryngol 28:309-15. 2007
    ..However, limited BMS-275183 studies have been performed in head and neck squamous cell carcinoma (HNSCC) cell lines. The purpose of this study is to identify the biological activity of BMS-275183 on HNSCC...
  10. ncbi request reprint Docetaxel induced gene expression patterns in head and neck squamous cell carcinoma using cDNA microarray and PowerBlot
    George H Yoo
    Department of Otolaryngology Head and Neck Surgery, Wayne State University and Karmanos Cancer Institute, Detroit, Michigan 48201, USA
    Clin Cancer Res 8:3910-21. 2002
    ..The purpose is to identify gene expression patterns induced by docetaxelin head and neck squamous carcinoma (HNSCC) cells using high throughput techniques...
  11. doi request reprint Combining human and rat sequences in her-2 DNA vaccines blunts immune tolerance and drives antitumor immunity
    Jennifer B Jacob
    Karmanos Cancer Institute, Wayne State University, Detroit, Michigan 48201, USA
    Cancer Res 70:119-28. 2010
    ..Our findings show that a strategy of combining heterologous antigen with self-antigens could produce a potent DNA vaccine that may be applicable to other tumor-associated antigens...
  12. ncbi request reprint Enhancement of Ad-p53 therapy with docetaxel in head and neck cancer
    George H Yoo
    Department of Otolaryngology Head and Neck Surgery, Wayne State University, Detroit, Michigan 48201, USA
    Laryngoscope 114:1871-9. 2004
    ..The objective of this project was to determine the mechanisms in which docetaxel enhances Ad-p53 tumor suppressive effects in head and neck cancer...
  13. ncbi request reprint An in vivo evaluation of docetaxel delivered intratumorally in head and neck squamous cell carcinoma
    George H Yoo
    Department of Otolaryngology Head and Neck Surgery, Division of Hematology Oncology, Wayne State University, Detroit, MI 48201, USA
    Arch Otolaryngol Head Neck Surg 131:418-29. 2005
    ..To identify activity and biological mechanisms of intratumoral (IT) docetaxel on head and neck squamous cell carcinoma (HNSCC)...
  14. ncbi request reprint Anticancer activity of docetaxel in murine salivary gland carcinoma
    Marie P Piechocki
    Department of Otolaryngology Head and Neck Surgery, Wayne State University and Karmanos Cancer Institute, Detroit, Michigan 48201, USA
    Clin Cancer Res 8:870-7. 2002
    ..The purpose of this study was to evaluate the biological mechanisms of docetaxel (TXT) on salivary gland carcinoma...
  15. pmc Intratumoral DNA electroporation induces anti-tumor immunity and tumor regression
    Olga Radkevich-Brown
    Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA
    Cancer Immunol Immunother 59:409-17. 2010
    ..Intratumoral expression of immune-modulating molecules may be most suitable in the neoadjuvant setting to enhance the therapeutic efficacy and provide long-term protection...
  16. ncbi request reprint Human ErbB-2 (Her-2) transgenic mice: a model system for testing Her-2 based vaccines
    Marie P Piechocki
    Karmanos Cancer Institute, Department of Otolaryngology, School of Medicine, Wayne State University, Detroit, MI 48201, USA
    J Immunol 171:5787-94. 2003
    ..The breakable tolerance of Her-2 Tg mice resembles that in human and these mice are particularly suited for testing human ErbB-2 based vaccines...
  17. ncbi request reprint In vivo characteristics of HPV-immortalized and carcinogen transformed oral keratinocytes
    George H Yoo
    Department of Otolaryngology Head and Neck Surgery, Wayne State University and Karmanos Cancer Institute, Detroit, Michigan 48201, USA
    Laryngoscope 112:1672-9. 2002
    ..To characterize in vivo features of HPV-immortalized and carcinogen transformed oral keratinocytes...
  18. pmc Induction of proapoptotic antibodies to triple-negative breast cancer by vaccination with TRAIL death receptor DR5 DNA
    Marie P Piechocki
    Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA
    Int J Cancer 131:2562-72. 2012
    ..These findings support DR5 as a promising vaccine target for controlling TNBC and other DR5-positive cancers...
  19. pmc DNA vaccination controls Her-2+ tumors that are refractory to targeted therapies
    Paula J Whittington
    Department of Immunology and Microbiology, School of Medicine, Wayne State University, Detroit, Michigan 48201, USA
    Cancer Res 68:7502-11. 2008
    ..These results warrant Her-2 vaccination whether tumor cells are sensitive or resistant to Her-2-targeted drugs or antibody therapy...
  20. pmc Inhibition of breast tumor growth and angiogenesis by a medicinal herb: Ocimum gratissimum
    Pratima Nangia-Makker
    Tumor Progression and Metastasis, Karmanos Cancer Institute, Wayne State University, School of Medicine, Detroit, MI 48201, USA
    Int J Cancer 121:884-94. 2007
    ....
  21. ncbi request reprint Role of Rho-family GTPase Cdc42 in polarized expression of lymphocyte appendages
    Stuart Ratner
    Breast Cancer Research Program and Stem Cell Transplantation Program, Barbara Ann Karmanos Cancer Institute, Detroit, Michigan 48201, USA
    J Leukoc Biol 73:830-40. 2003
    ..The results suggest that one role of Cdc42 in lymphocyte motility is to preserve polarity by concentrating lamellipodial disassembly signals in the uropod...