Research Topics
| K Luan PhanSummaryAffiliation: Wayne State University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Functional neuroimaging studies of human emotionsK Luan Phan
Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, Michigan 48201, USA
CNS Spectr 9:258-66. 2004..This paper will review observations in several regions of interest in limbic (eg, amygdala, anterior cingulate cortex) and paralimbic (eg, medial prefrontal cortex, insula) brain regions in emotional responding...- Neural correlates of individual ratings of emotional salience: a trial-related fMRI studyK Luan Phan
Department of Psychiatry and Behvioral Neuroscience, Wayne State University School of Medicine, Detroit, MI 48201, USA
Neuroimage 21:768-80. 2004..The findings highlight both overlapping and segregated neural representations of intrinsic value and personal relevance during the appraisal of emotional stimuli... - Real-time fMRI of cortico-limbic brain activity during emotional processingK Luan Phan
Brain Imaging Research Division, Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, 9B University Health Center Rm 18, 4201 St Antoine Blvd, Detroit, MI 48201, USA
Neuroreport 15:527-32. 2004..Detecting cortico-limbic brain activation during perception and experience of emotionally salient visual stimuli with real-time fMRI technology is feasible... - Corticolimbic blood flow during nontraumatic emotional processing in posttraumatic stress disorderK Luan Phan
Department of Psychiatry, Pritzker School of Medicine, The University of Chicago, Chicago, Ill, USA
Arch Gen Psychiatry 63:184-92. 2006..Activation of the amygdala and lack of ventral MPFC deactivation to negatively valenced images in combat controls may reflect compensatory changes after trauma exposure that are not associated with PTSD... - Neural correlates of internally-generated disgust via autobiographical recall: a functional magnetic resonance imaging investigationDaniel A Fitzgerald
Clinical Neuroscience and Psychopharmacology Research Unit, Department of Psychiatry, University of Chicago, Chicago, IL, USA
Neurosci Lett 370:91-6. 2004..These findings suggest that areas previously associated with the perception of disgust (e.g., insula, basal ganglia) are also involved interoceptive experience of disgust... - Neural correlates of social and nonsocial emotions: An fMRI studyJennifer C Britton
Neuroscience Program, University of Michigan, Ann Arbor, MI 48109
Neuroimage 31:397-409. 2006..Overall, these findings highlight that sociality has a key role in processing emotional valence, which may have implications for patient populations with social and emotional deficits... - Neural substrates for voluntary suppression of negative affect: a functional magnetic resonance imaging studyK Luan Phan
Department of Psychiatry, University of Chicago, Chicago, Illinois 60637 1470, USA
Biol Psychiatry 57:210-9. 2005..Although the capacity to regulate emotions is critical to mental well-being, its neural substrates remain unclear... - Beyond threat: amygdala reactivity across multiple expressions of facial affectDaniel A Fitzgerald
Department of Psychiatry, The University of Chicago, 5841 South Maryland Avenue MC3077 (L-466C, Chicago, IL 60637-1470, USA
Neuroimage 30:1441-8. 2006..These results challenge the notion that the amygdala has a specialized role in processing certain emotions and suggest that the amygdala may have a more general-purpose function in processing salient information from faces... - Association between amygdala hyperactivity to harsh faces and severity of social anxiety in generalized social phobiaK Luan Phan
Department of Psychiatry, Biological Sciences Division, The University of Chicago, Chicago, Illinois 60637, USA
Biol Psychiatry 59:424-9. 2006.... - Altered central micro-opioid receptor binding after psychological traumaIsrael Liberzon
Department of Psychiatry, University of Michigan Medical School, Ann Arbor, Michigan 48109 0118, USA
Biol Psychiatry 61:1030-8. 2007..The mu-opioid neurotransmitter system, implicated in responses to stress and suppression of pain, is distributed in and is thought to regulate the function of brain regions that are implicated in affective processing... - Neural response to emotional salience in schizophreniaStephan F Taylor
Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
Neuropsychopharmacology 30:984-95. 2005..Reduced modulation of visual cortex by emotionally salient stimuli also suggests a failure to organize cerebral activity at a global level... - Amygdala reactivity to emotional faces at high and low intensity in generalized social phobia: a 4-Tesla functional MRI studyK Lira Yoon
Brain Imaging and Emotions Laboratory, Department of Psychiatry, University of Chicago, Chicago, IL 60637 1470, USA
Psychiatry Res 154:93-8. 2007..low) intensity expressions in the phobic group, suggesting that more arousing social-emotional cues contribute to limbic hyperactivity in GSP... - Amygdala and orbitofrontal reactivity to social threat in individuals with impulsive aggressionEmil F Coccaro
Department of Psychiatry, Biological Sciences Division and the Pritzker School of Medicine, The University of Chicago, Chicago, Illinois 60637 1470, USA
Biol Psychiatry 62:168-78. 2007..In this study we employed a social-emotional probe of amygdala-OFC function in individuals with impulsive aggression... - Habituation of rostral anterior cingulate cortex to repeated emotionally salient picturesK Luan Phan
Department of Psychiatry, University of Michigan, Ann Arbor, Ann Arbor, MI, USA
Neuropsychopharmacology 28:1344-50. 2003..These findings highlight the phasic activity of the rACC in emotional processing consistent with habituation... - Subjective rating of emotionally salient stimuli modulates neural activityStephan F Taylor
Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
Neuroimage 18:650-9. 2003..For both RTNG and PSVW, subjects activated the left fusiform gyrus. The results support the proposition that task instructions about how subjects should process evocative stimuli can affect neural activity... - Extended amygdala and emotional salience: a PET activation study of positive and negative affectIsrael Liberzon
Department of Psychiatry, University of Michigan, Ann Arbor, USA
Neuropsychopharmacology 28:726-33. 2003.... - Activation of the medial prefrontal cortex and extended amygdala by individual ratings of emotional arousal: a fMRI studyK Luan Phan
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109-0118, USA
Biol Psychiatry 53:211-5. 2003..CONCLUSIONS: Our findings demonstrate that individual behavioral data are useful in improving detection of activation in block-design functional imaging studies... - Paralimbic and medial prefrontal cortical involvement in neuroendocrine responses to traumatic stimuliIsrael Liberzon
Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA
Am J Psychiatry 164:1250-8. 2007..The authors used [(15)O]H(2)O positron emission tomography (PET) on subjects with posttraumatic stress disorder (PTSD) to study these circuits... - Corticolimbic blood flow in posttraumatic stress disorder during script-driven imageryJennifer C Britton
Neuroscience Program, University of Michigan, Michigan, USA
Biol Psychiatry 57:832-40. 2005..CONCLUSIONS: Trauma-specific patterns may represent potential compensatory changes to traumatic reminders, while patterns observed only in the PTSD group may reflect neural substrates specific to PTSD pathophysiology... - Acute serotonin and dopamine depletion improves attentional control: findings from the stroop taskKirsty E Scholes
Behavioural Neuroscience Laboratory, Department of Physiology, Monash Centre for Brain and Behavior, Monash University, Melbourne, Vic, Australia
Neuropsychopharmacology 32:1600-10. 2007..These findings enhance our understanding of the neurochemical basis of attentional control and the possible cause of attentional control deficits in schizophrenia... - Neural correlates of telling lies: a functional magnetic resonance imaging study at 4 TeslaK Luan Phan
Department of Psychiatry, Pritzker School of Medicine, University of Chicago, Chicago, IL 60637, USA
Acad Radiol 12:164-72. 2005.... - Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRIK Luan Phan
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109, USA
Neuroimage 16:331-48. 2002..This review provides a critical comparison of findings across individual studies and suggests that separate brain regions are involved in different aspects of emotion... - Valence, gender, and lateralization of functional brain anatomy in emotion: a meta-analysis of findings from neuroimagingTor D Wager
Department of Psychology, University of Michigan, Ann Arbor, MI 48109, USA
Neuroimage 19:513-31. 2003..The study provides evidence that lateralization of emotional activity is more complex and region-specific than predicted by previous theories of emotion and the brain... - Neural correlates of traumatic recall in posttraumatic stress disorderIsrael Liberzon
Psychiatry Service, Ann Arbor Veterans Affairs Medical Center, MI 48109, USA
Stress 6:151-6. 2003.... - A functional neuroimaging study of motivation and executive functionStephan F Taylor
Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109 0118, USA
Neuroimage 21:1045-54. 2004..Areas of overlap and interaction may integrate information about value, or they may represent a general effect of motivation increasing neural effort... - Brain-imaging studies of posttraumatic stress disorderIsrael Liberzon
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA
CNS Spectr 8:641-50. 2003..This article reviews the literature on structural, functional, and neurochemical brain-imaging studies of PTSD... - Nonstationary cluster-size inference with random field and permutation methodsSatoru Hayasaka
Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109-2029, USA
Neuroimage 22:676-87. 2004..We include a detailed and consolidated description of Worsley nonstationary RFT cluster-size test... 
mu-Opioid receptors and limbic responses to aversive emotional stimuliIsrael Liberzon
Department of Psychiatry, Veterans Administration Medical Center, University of Michigan, Ann Arbor, MI 48105, USA
Proc Natl Acad Sci U S A 99:7084-9. 2002..This is consistent with an inhibitory/anxiolytic role of the endogenous opioid system in limbic regions of the temporal lobe and basal forebrain...- Neuroimaging and personality disordersMichael S McCloskey
Department of Psychiatry, MC 3077, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA
Curr Psychiatry Rep 7:65-72. 2005.... - Cannabinoid modulation of amygdala reactivity to social signals of threat in humansK Luan Phan
Department of Psychiatry, University of Michigan and Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan 48109, USA
J Neurosci 28:2313-9. 2008....