K Luan Phan

Summary

Affiliation: Wayne State University
Country: USA

Publications

  1. ncbi request reprint Functional neuroimaging studies of human emotions
    K Luan Phan
    Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, Michigan 48201, USA
    CNS Spectr 9:258-66. 2004
  2. ncbi request reprint Neural correlates of individual ratings of emotional salience: a trial-related fMRI study
    K Luan Phan
    Department of Psychiatry and Behvioral Neuroscience, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Neuroimage 21:768-80. 2004
  3. ncbi request reprint Real-time fMRI of cortico-limbic brain activity during emotional processing
    K Luan Phan
    Brain Imaging Research Division, Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, 9B University Health Center Rm 18, 4201 St Antoine Blvd, Detroit, MI 48201, USA
    Neuroreport 15:527-32. 2004
  4. ncbi request reprint Corticolimbic blood flow during nontraumatic emotional processing in posttraumatic stress disorder
    K Luan Phan
    Department of Psychiatry, Pritzker School of Medicine, The University of Chicago, Chicago, Ill, USA
    Arch Gen Psychiatry 63:184-92. 2006
  5. ncbi request reprint Neural correlates of internally-generated disgust via autobiographical recall: a functional magnetic resonance imaging investigation
    Daniel A Fitzgerald
    Clinical Neuroscience and Psychopharmacology Research Unit, Department of Psychiatry, University of Chicago, Chicago, IL, USA
    Neurosci Lett 370:91-6. 2004
  6. ncbi request reprint Neural correlates of social and nonsocial emotions: An fMRI study
    Jennifer C Britton
    Neuroscience Program, University of Michigan, Ann Arbor, MI 48109
    Neuroimage 31:397-409. 2006
  7. ncbi request reprint Neural substrates for voluntary suppression of negative affect: a functional magnetic resonance imaging study
    K Luan Phan
    Department of Psychiatry, University of Chicago, Chicago, Illinois 60637 1470, USA
    Biol Psychiatry 57:210-9. 2005
  8. ncbi request reprint Beyond threat: amygdala reactivity across multiple expressions of facial affect
    Daniel A Fitzgerald
    Department of Psychiatry, The University of Chicago, 5841 South Maryland Avenue MC3077 L 466C, Chicago, IL 60637 1470, USA
    Neuroimage 30:1441-8. 2006
  9. ncbi request reprint Association between amygdala hyperactivity to harsh faces and severity of social anxiety in generalized social phobia
    K Luan Phan
    Department of Psychiatry, Biological Sciences Division, The University of Chicago, Chicago, Illinois 60637, USA
    Biol Psychiatry 59:424-9. 2006
  10. ncbi request reprint Altered central micro-opioid receptor binding after psychological trauma
    Israel Liberzon
    Department of Psychiatry, University of Michigan Medical School, Ann Arbor, Michigan 48109 0118, USA
    Biol Psychiatry 61:1030-8. 2007

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Functional neuroimaging studies of human emotions
    K Luan Phan
    Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, Michigan 48201, USA
    CNS Spectr 9:258-66. 2004
    ..This paper will review observations in several regions of interest in limbic (eg, amygdala, anterior cingulate cortex) and paralimbic (eg, medial prefrontal cortex, insula) brain regions in emotional responding...
  2. ncbi request reprint Neural correlates of individual ratings of emotional salience: a trial-related fMRI study
    K Luan Phan
    Department of Psychiatry and Behvioral Neuroscience, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Neuroimage 21:768-80. 2004
    ..The findings highlight both overlapping and segregated neural representations of intrinsic value and personal relevance during the appraisal of emotional stimuli...
  3. ncbi request reprint Real-time fMRI of cortico-limbic brain activity during emotional processing
    K Luan Phan
    Brain Imaging Research Division, Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, 9B University Health Center Rm 18, 4201 St Antoine Blvd, Detroit, MI 48201, USA
    Neuroreport 15:527-32. 2004
    ..Detecting cortico-limbic brain activation during perception and experience of emotionally salient visual stimuli with real-time fMRI technology is feasible...
  4. ncbi request reprint Corticolimbic blood flow during nontraumatic emotional processing in posttraumatic stress disorder
    K Luan Phan
    Department of Psychiatry, Pritzker School of Medicine, The University of Chicago, Chicago, Ill, USA
    Arch Gen Psychiatry 63:184-92. 2006
    ..However, the relationship between activity in these regions and general emotional processing unrelated to traumatic experience has not been fully examined...
  5. ncbi request reprint Neural correlates of internally-generated disgust via autobiographical recall: a functional magnetic resonance imaging investigation
    Daniel A Fitzgerald
    Clinical Neuroscience and Psychopharmacology Research Unit, Department of Psychiatry, University of Chicago, Chicago, IL, USA
    Neurosci Lett 370:91-6. 2004
    ..These findings suggest that areas previously associated with the perception of disgust (e.g., insula, basal ganglia) are also involved interoceptive experience of disgust...
  6. ncbi request reprint Neural correlates of social and nonsocial emotions: An fMRI study
    Jennifer C Britton
    Neuroscience Program, University of Michigan, Ann Arbor, MI 48109
    Neuroimage 31:397-409. 2006
    ..Overall, these findings highlight that sociality has a key role in processing emotional valence, which may have implications for patient populations with social and emotional deficits...
  7. ncbi request reprint Neural substrates for voluntary suppression of negative affect: a functional magnetic resonance imaging study
    K Luan Phan
    Department of Psychiatry, University of Chicago, Chicago, Illinois 60637 1470, USA
    Biol Psychiatry 57:210-9. 2005
    ..Although the capacity to regulate emotions is critical to mental well-being, its neural substrates remain unclear...
  8. ncbi request reprint Beyond threat: amygdala reactivity across multiple expressions of facial affect
    Daniel A Fitzgerald
    Department of Psychiatry, The University of Chicago, 5841 South Maryland Avenue MC3077 L 466C, Chicago, IL 60637 1470, USA
    Neuroimage 30:1441-8. 2006
    ..These results challenge the notion that the amygdala has a specialized role in processing certain emotions and suggest that the amygdala may have a more general-purpose function in processing salient information from faces...
  9. ncbi request reprint Association between amygdala hyperactivity to harsh faces and severity of social anxiety in generalized social phobia
    K Luan Phan
    Department of Psychiatry, Biological Sciences Division, The University of Chicago, Chicago, Illinois 60637, USA
    Biol Psychiatry 59:424-9. 2006
    ....
  10. ncbi request reprint Altered central micro-opioid receptor binding after psychological trauma
    Israel Liberzon
    Department of Psychiatry, University of Michigan Medical School, Ann Arbor, Michigan 48109 0118, USA
    Biol Psychiatry 61:1030-8. 2007
    ..The mu-opioid neurotransmitter system, implicated in responses to stress and suppression of pain, is distributed in and is thought to regulate the function of brain regions that are implicated in affective processing...
  11. ncbi request reprint Neural response to emotional salience in schizophrenia
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
    Neuropsychopharmacology 30:984-95. 2005
    ..Reduced modulation of visual cortex by emotionally salient stimuli also suggests a failure to organize cerebral activity at a global level...
  12. ncbi request reprint Amygdala reactivity to emotional faces at high and low intensity in generalized social phobia: a 4-Tesla functional MRI study
    K Lira Yoon
    Brain Imaging and Emotions Laboratory, Department of Psychiatry, University of Chicago, Chicago, IL 60637 1470, USA
    Psychiatry Res 154:93-8. 2007
    ..low) intensity expressions in the phobic group, suggesting that more arousing social-emotional cues contribute to limbic hyperactivity in GSP...
  13. ncbi request reprint Amygdala and orbitofrontal reactivity to social threat in individuals with impulsive aggression
    Emil F Coccaro
    Department of Psychiatry, Biological Sciences Division and the Pritzker School of Medicine, The University of Chicago, Chicago, Illinois 60637 1470, USA
    Biol Psychiatry 62:168-78. 2007
    ..In this study we employed a social-emotional probe of amygdala-OFC function in individuals with impulsive aggression...
  14. ncbi request reprint Habituation of rostral anterior cingulate cortex to repeated emotionally salient pictures
    K Luan Phan
    Department of Psychiatry, University of Michigan, Ann Arbor, Ann Arbor, MI, USA
    Neuropsychopharmacology 28:1344-50. 2003
    ..These findings highlight the phasic activity of the rACC in emotional processing consistent with habituation...
  15. ncbi request reprint Subjective rating of emotionally salient stimuli modulates neural activity
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
    Neuroimage 18:650-9. 2003
    ..For both RTNG and PSVW, subjects activated the left fusiform gyrus. The results support the proposition that task instructions about how subjects should process evocative stimuli can affect neural activity...
  16. ncbi request reprint Extended amygdala and emotional salience: a PET activation study of positive and negative affect
    Israel Liberzon
    Department of Psychiatry, University of Michigan, Ann Arbor, USA
    Neuropsychopharmacology 28:726-33. 2003
    ....
  17. ncbi request reprint Activation of the medial prefrontal cortex and extended amygdala by individual ratings of emotional arousal: a fMRI study
    K Luan Phan
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109 0118, USA
    Biol Psychiatry 53:211-5. 2003
    ....
  18. ncbi request reprint Paralimbic and medial prefrontal cortical involvement in neuroendocrine responses to traumatic stimuli
    Israel Liberzon
    Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA
    Am J Psychiatry 164:1250-8. 2007
    ..The authors used [(15)O]H(2)O positron emission tomography (PET) on subjects with posttraumatic stress disorder (PTSD) to study these circuits...
  19. ncbi request reprint Corticolimbic blood flow in posttraumatic stress disorder during script-driven imagery
    Jennifer C Britton
    Neuroscience Program, University of Michigan, Michigan, USA
    Biol Psychiatry 57:832-40. 2005
    ..The present study examined both PTSD-specific and trauma-specific regional cerebral blood flow (rCBF) patterns during script-driven imagery...
  20. ncbi request reprint Acute serotonin and dopamine depletion improves attentional control: findings from the stroop task
    Kirsty E Scholes
    Behavioural Neuroscience Laboratory, Department of Physiology, Monash Centre for Brain and Behavior, Monash University, Melbourne, Vic, Australia
    Neuropsychopharmacology 32:1600-10. 2007
    ..These findings enhance our understanding of the neurochemical basis of attentional control and the possible cause of attentional control deficits in schizophrenia...
  21. ncbi request reprint Neural correlates of telling lies: a functional magnetic resonance imaging study at 4 Tesla
    K Luan Phan
    Department of Psychiatry, Pritzker School of Medicine, University of Chicago, Chicago, IL 60637, USA
    Acad Radiol 12:164-72. 2005
    ....
  22. ncbi request reprint Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRI
    K Luan Phan
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109, USA
    Neuroimage 16:331-48. 2002
    ..This review provides a critical comparison of findings across individual studies and suggests that separate brain regions are involved in different aspects of emotion...
  23. ncbi request reprint Valence, gender, and lateralization of functional brain anatomy in emotion: a meta-analysis of findings from neuroimaging
    Tor D Wager
    Department of Psychology, University of Michigan, Ann Arbor, MI 48109, USA
    Neuroimage 19:513-31. 2003
    ..The study provides evidence that lateralization of emotional activity is more complex and region-specific than predicted by previous theories of emotion and the brain...
  24. ncbi request reprint Neural correlates of traumatic recall in posttraumatic stress disorder
    Israel Liberzon
    Psychiatry Service, Ann Arbor Veterans Affairs Medical Center, MI 48109, USA
    Stress 6:151-6. 2003
    ....
  25. ncbi request reprint A functional neuroimaging study of motivation and executive function
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109 0118, USA
    Neuroimage 21:1045-54. 2004
    ..Areas of overlap and interaction may integrate information about value, or they may represent a general effect of motivation increasing neural effort...
  26. ncbi request reprint Brain-imaging studies of posttraumatic stress disorder
    Israel Liberzon
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA
    CNS Spectr 8:641-50. 2003
    ..This article reviews the literature on structural, functional, and neurochemical brain-imaging studies of PTSD...
  27. ncbi request reprint Nonstationary cluster-size inference with random field and permutation methods
    Satoru Hayasaka
    Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109 2029, USA
    Neuroimage 22:676-87. 2004
    ..We include a detailed and consolidated description of Worsley nonstationary RFT cluster-size test...
  28. pmc mu-Opioid receptors and limbic responses to aversive emotional stimuli
    Israel Liberzon
    Department of Psychiatry, Veterans Administration Medical Center, University of Michigan, Ann Arbor, MI 48105, USA
    Proc Natl Acad Sci U S A 99:7084-9. 2002
    ..This is consistent with an inhibitory/anxiolytic role of the endogenous opioid system in limbic regions of the temporal lobe and basal forebrain...
  29. ncbi request reprint Neuroimaging and personality disorders
    Michael S McCloskey
    Department of Psychiatry, MC 3077, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA
    Curr Psychiatry Rep 7:65-72. 2005
    ....
  30. pmc Cannabinoid modulation of amygdala reactivity to social signals of threat in humans
    K Luan Phan
    Department of Psychiatry, University of Michigan and Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan 48109, USA
    J Neurosci 28:2313-9. 2008
    ....