Fangyu Peng

Summary

Affiliation: Wayne State University
Country: USA

Publications

  1. ncbi request reprint Synthesis of Poly[APMA]-DOTA-64Cu conjugates for interventional radionuclide therapy of prostate cancer: assessment of intratumoral retention by micro-positron emission tomography
    Jianchao Yuan
    Department of Pediatrics, Wayne State University, Detroit, MI, USA
    Mol Imaging 6:10-7. 2007
  2. ncbi request reprint Mouse extrahepatic hepatoma detected on MicroPET using copper (II)-64 chloride uptake mediated by endogenous mouse copper transporter 1
    Fangyu Peng
    Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI, USA
    Mol Imaging Biol 7:325-9. 2005
  3. ncbi request reprint Use of 2-deoxy-2-[F-18]-fluoro-D-glucose positron emission tomography to monitor therapeutic response by rhabdomyosarcoma in children: report of a retrospective case study
    Fangyu Peng
    The Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    Clin Nucl Med 31:394-7. 2006
  4. ncbi request reprint PET of human prostate cancer xenografts in mice with increased uptake of 64CuCl2
    Fangyu Peng
    Department of Pediatrics, School of Medicine, Wayne State University, Detroit, Michigan 48201, USA
    J Nucl Med 47:1649-52. 2006
  5. doi request reprint Potent anticancer activity of pyrrolidine dithiocarbamate-copper complex against cisplatin-resistant neuroblastoma cells
    Haiyuan Zhang
    aCarman and Ann Adams Department of Pediatrics bDepartment of Radiology cBarbara Ann Karmanos Cancer Institute, School of Medicine, Wayne State University, Detroit, Michigan, USA
    Anticancer Drugs 19:125-32. 2008
  6. pmc Quantification of tryptophan transport and metabolism in lung tumors using PET
    Csaba Juhasz
    PET Center, Children s Hospital of Michigan, Wayne State University, Detroit, Michigan, USA
    J Nucl Med 50:356-63. 2009
  7. doi request reprint Positron emission tomography of human hepatocellular carcinoma xenografts in mice using copper (II)-64 chloride as a tracer with copper (II)-64 chloride
    Haiyuan Zhang
    Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI, USA
    Acad Radiol 18:1561-8. 2011
  8. ncbi request reprint Synthesis and characterization of new copper thiosemicarbazone complexes with an ONNS quadridentate system: cell growth inhibition, S-phase cell cycle arrest and proapoptotic activities on cisplatin-resistant neuroblastoma cells
    Haiyuan Zhang
    Carman and Ann Adams Department of Pediatrics, Wayne State University, Detroit, MI 48201, USA
    J Biol Inorg Chem 13:47-55. 2008
  9. pmc Urinary copper elevation in a mouse model of Wilson's disease is a regulated process to specifically decrease the hepatic copper load
    Lawrence W Gray
    Department of Physiology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA
    PLoS ONE 7:e38327. 2012
  10. ncbi request reprint Synthesis and characterization of theranostic poly(HPMA)-c(RGDyK)-DOTA-64Cu copolymer targeting tumor angiogenesis: tumor localization visualized by positron emission tomography
    Jianchao Yuan
    Carman and Ann Adams Department of Pediatrics, Wayne State University, Detroit, MI, USA
    Mol Imaging 12:203-12. 2013

Research Grants

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Synthesis of Poly[APMA]-DOTA-64Cu conjugates for interventional radionuclide therapy of prostate cancer: assessment of intratumoral retention by micro-positron emission tomography
    Jianchao Yuan
    Department of Pediatrics, Wayne State University, Detroit, MI, USA
    Mol Imaging 6:10-7. 2007
    ..The data suggest that the poly[APMA]-DOTA-(64)Cu conjugates might be useful for interventional radionuclide therapy of locally recurrent prostate cancer in humans...
  2. ncbi request reprint Mouse extrahepatic hepatoma detected on MicroPET using copper (II)-64 chloride uptake mediated by endogenous mouse copper transporter 1
    Fangyu Peng
    Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI, USA
    Mol Imaging Biol 7:325-9. 2005
    ..This study was conducted to assess the positron-emitting copper (II)-64 chloride ((64)CuCl(2)) as a probe for imaging mouse extrahepatic hepatoma expressing mouse copper transporter 1 (mCtr1) with positron emission tomography (PET)...
  3. ncbi request reprint Use of 2-deoxy-2-[F-18]-fluoro-D-glucose positron emission tomography to monitor therapeutic response by rhabdomyosarcoma in children: report of a retrospective case study
    Fangyu Peng
    The Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    Clin Nucl Med 31:394-7. 2006
    ..The purpose of this study was to study the use of 2-deoxy-2-[F-18]-fluoro-D-glucose positron emission tomography (F-18 FDG PET) for monitoring therapeutic response by rhabdomyosarcoma (RMSA) in children...
  4. ncbi request reprint PET of human prostate cancer xenografts in mice with increased uptake of 64CuCl2
    Fangyu Peng
    Department of Pediatrics, School of Medicine, Wayne State University, Detroit, Michigan 48201, USA
    J Nucl Med 47:1649-52. 2006
    ..Our objective was to determine whether human prostate cancer xenografts in mice can be localized by PET using 64CuCl2 as a probe (64Cu PET)...
  5. doi request reprint Potent anticancer activity of pyrrolidine dithiocarbamate-copper complex against cisplatin-resistant neuroblastoma cells
    Haiyuan Zhang
    aCarman and Ann Adams Department of Pediatrics bDepartment of Radiology cBarbara Ann Karmanos Cancer Institute, School of Medicine, Wayne State University, Detroit, Michigan, USA
    Anticancer Drugs 19:125-32. 2008
    ..The Cu(PDTC)2 complex holds potential as a new drug for the treatment of refractory neuroblastoma in children...
  6. pmc Quantification of tryptophan transport and metabolism in lung tumors using PET
    Csaba Juhasz
    PET Center, Children s Hospital of Michigan, Wayne State University, Detroit, Michigan, USA
    J Nucl Med 50:356-63. 2009
    ..The goal of this study was to evaluate the in vivo kinetics of alpha-(11)C-methyl-l-tryptophan (AMT), a PET tracer for tryptophan metabolism, in human lung tumors...
  7. doi request reprint Positron emission tomography of human hepatocellular carcinoma xenografts in mice using copper (II)-64 chloride as a tracer with copper (II)-64 chloride
    Haiyuan Zhang
    Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI, USA
    Acad Radiol 18:1561-8. 2011
    ..The aim of this study was to assess copper metabolism of human hepatocellular carcinoma (HCC) with positron emission tomographic (PET) imaging using copper (II)-64 chloride ((64)CuCl(2)) as a tracer...
  8. ncbi request reprint Synthesis and characterization of new copper thiosemicarbazone complexes with an ONNS quadridentate system: cell growth inhibition, S-phase cell cycle arrest and proapoptotic activities on cisplatin-resistant neuroblastoma cells
    Haiyuan Zhang
    Carman and Ann Adams Department of Pediatrics, Wayne State University, Detroit, MI 48201, USA
    J Biol Inorg Chem 13:47-55. 2008
    ..The data obtained in this study suggest that CuHQDMTS and CuHQTS hold potential as new, effective drugs for treatment of refractory neuroblastoma in children...
  9. pmc Urinary copper elevation in a mouse model of Wilson's disease is a regulated process to specifically decrease the hepatic copper load
    Lawrence W Gray
    Department of Physiology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA
    PLoS ONE 7:e38327. 2012
    ..These results demonstrate that the body regulates copper export through more than one mechanism; better understanding of urinary copper excretion may contribute to an improved diagnosis and monitoring of WD...
  10. ncbi request reprint Synthesis and characterization of theranostic poly(HPMA)-c(RGDyK)-DOTA-64Cu copolymer targeting tumor angiogenesis: tumor localization visualized by positron emission tomography
    Jianchao Yuan
    Carman and Ann Adams Department of Pediatrics, Wayne State University, Detroit, MI, USA
    Mol Imaging 12:203-12. 2013
    ..004). The poly(HPMA)-c(RGDyK)-DOTA-64Cu copolymers hold potential as a theranostic scaffold for cancer imaging and radiochemotherapy of prostate cancer targeting tumor angiogenesis by noninvasive tracking with PET...
  11. ncbi request reprint Assessment of progression and treatment response of optic pathway glioma with positron emission tomography using alpha-[(11)C]methyl-L-tryptophan
    Fangyu Peng
    The Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Mol Imaging Biol 9:106-9. 2007
    ..To report the utility of positron emission tomography (PET) with alpha-[(11)C]methyl-L-tryptophan (AMT) for monitoring progression and response to treatment of an isolated optic pathway glioma (OPG) in a 16-year-old girl...
  12. ncbi request reprint Synthesis, structure, and anticancer activity of gallium(III) complexes with asymmetric tridentate ligands: growth inhibition and apoptosis induction of cisplatin-resistant neuroblastoma cells
    Rajendra Shakya
    Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, MI 48202, USA
    Inorg Chem 45:6263-8. 2006
    ..e., 3-5, showed activity superior to that observed for cisplatin and induced apoptosis of neuroblastoma cells. Nitro-containing 2 suppressed proliferation of the neuroblastoma cells but induced apoptosis less effectively...
  13. ncbi request reprint Inhibition of prostate cancer cellular proteasome activity by a pyrrolidine dithiocarbamate-copper complex is associated with suppression of proliferation and induction of apoptosis
    Di Chen
    Barbara Ann Karmanos Cancer Institute, Department of Pathology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    Front Biosci 10:2932-9. 2005
    ....
  14. doi request reprint Positron emission tomography in subcutaneous panniculitis-like T-cell lymphoma
    Victor R Rodriguez
    Carman and Ann Adams Department of Pediatrics, Division of Radiology, Children s Hospital of Michigan, Wayne State University School of Medicine, Detroit, Michigan, USA
    Pediatr Blood Cancer 52:406-8. 2009
    ..Pre- and post-treatment positron emission tomography study demonstrated dramatic resolution of the subcutaneous lesions indicating its usefulness in SPTCL staging and treatment response monitoring...

Research Grants2