R D MacArthur

Summary

Affiliation: Wayne State University
Country: USA

Publications

  1. pmc Abacavir/lamivudine combination in the treatment of HIV: a review
    Geetha Sivasubramanian
    Division of Infectious Diseases, Wayne State University, Detroit, MI, USA
    Ther Clin Risk Manag 6:83-94. 2010
  2. pmc Profile of etravirine for the treatment of HIV infection
    Alice Tseng
    Toronto General Hospital, Toronto, ON, Canada
    Ther Clin Risk Manag 6:49-58. 2010
  3. doi request reprint Etiology and pharmacologic management of noninfectious diarrhea in HIV-infected individuals in the highly active antiretroviral therapy era
    Rodger D MacArthur
    Division of Infectious Diseases, Wayne State University, Detroit, Michigan 48201, USA
    Clin Infect Dis 55:860-7. 2012
  4. ncbi request reprint Understanding HIV phenotypic resistance testing: usefulness in managing treatment-experienced patients
    Rodger D MacArthur
    Wayne State University School of Medicine, Division of Infectious Diseases, Detroit, Michigan 48201, USA
    AIDS Rev 11:223-30. 2009
  5. ncbi request reprint Reviews of anti-infective agents: maraviroc: the first of a new class of antiretroviral agents
    Rodger D MacArthur
    Wayne State University, Detroit, Michigan, USA
    Clin Infect Dis 47:236-41. 2008
  6. ncbi request reprint Darunavir: promising initial results
    Rodger D MacArthur
    Wayne State University, Detroit, MI 48201, USA
    Lancet 369:1143-4. 2007
  7. ncbi request reprint Comparison of prognostic importance of latest CD4+ cell count and HIV RNA levels in patients with advanced HIV infection on highly active antiretroviral therapy
    Rodger D MacArthur
    Wayne State University, University Health Center, Detroit, Michigan 48201, USA
    HIV Clin Trials 6:127-35. 2005
  8. ncbi request reprint Efficacy and safety of abacavir plus lamivudine versus didanosine plus stavudine when combined with a protease inhibitor, a nonnucleoside reverse transcriptase inhibitor, or both in HIV-1 positive antiretroviral-naive persons
    R D MacArthur
    Department of Medicine, Division of Infectious Diseases, Wayne State University, Detroit, Michigan 48201, USA
    HIV Clin Trials 5:361-70. 2004
  9. ncbi request reprint Adequacy of early empiric antibiotic treatment and survival in severe sepsis: experience from the MONARCS trial
    Rodger D MacArthur
    Wayne State University, Detroit, Michigan 48201, USA
    Clin Infect Dis 38:284-8. 2004
  10. ncbi request reprint The rationale and design of the CPCRA (Terry Beirn Community Programs for Clinical Research on AIDS) 058 FIRST (Flexible Initial Retrovirus Suppressive Therapies) trial
    R D MacArthur
    University Health Center, Wayne State University, 4201 St Antoine, UHC 7 D, Detroit, MI 48201, USA
    Control Clin Trials 22:176-90. 2001

Collaborators

Detail Information

Publications33

  1. pmc Abacavir/lamivudine combination in the treatment of HIV: a review
    Geetha Sivasubramanian
    Division of Infectious Diseases, Wayne State University, Detroit, MI, USA
    Ther Clin Risk Manag 6:83-94. 2010
    ..This review will focus on the pharmacokinetics, activity, side effects, and resistance profile of both abacavir and lamivudine, including a thorough review of all of the recent studies relevant to both drugs...
  2. pmc Profile of etravirine for the treatment of HIV infection
    Alice Tseng
    Toronto General Hospital, Toronto, ON, Canada
    Ther Clin Risk Manag 6:49-58. 2010
    ..Etravirine offers a potent sequencing option after the development of resistance to first-line NNRTIs, and is a welcome addition to this established drug class...
  3. doi request reprint Etiology and pharmacologic management of noninfectious diarrhea in HIV-infected individuals in the highly active antiretroviral therapy era
    Rodger D MacArthur
    Division of Infectious Diseases, Wayne State University, Detroit, Michigan 48201, USA
    Clin Infect Dis 55:860-7. 2012
    ..New therapies targeting the pathogenic mechanisms of noninfectious diarrheas are needed...
  4. ncbi request reprint Understanding HIV phenotypic resistance testing: usefulness in managing treatment-experienced patients
    Rodger D MacArthur
    Wayne State University School of Medicine, Division of Infectious Diseases, Detroit, Michigan 48201, USA
    AIDS Rev 11:223-30. 2009
    ..An understanding of the basic principles of phenotypic resistance testing is crucial for providing optimal care, particularly for antiretroviral-experienced patients...
  5. ncbi request reprint Reviews of anti-infective agents: maraviroc: the first of a new class of antiretroviral agents
    Rodger D MacArthur
    Wayne State University, Detroit, Michigan, USA
    Clin Infect Dis 47:236-41. 2008
    ..HIV-1 mechanisms of resistance to maraviroc, assays to determine viral coreceptor use (tropism), drug safety, and clinical use of maraviroc are discussed at length...
  6. ncbi request reprint Darunavir: promising initial results
    Rodger D MacArthur
    Wayne State University, Detroit, MI 48201, USA
    Lancet 369:1143-4. 2007
  7. ncbi request reprint Comparison of prognostic importance of latest CD4+ cell count and HIV RNA levels in patients with advanced HIV infection on highly active antiretroviral therapy
    Rodger D MacArthur
    Wayne State University, University Health Center, Detroit, Michigan 48201, USA
    HIV Clin Trials 6:127-35. 2005
    ..The comparative prognostic importance of latest plasma HIV RNA levels (viral loads) and CD4+ cell counts among patients prescribed highly active antiretroviral therapy (HAART) has not been well characterized...
  8. ncbi request reprint Efficacy and safety of abacavir plus lamivudine versus didanosine plus stavudine when combined with a protease inhibitor, a nonnucleoside reverse transcriptase inhibitor, or both in HIV-1 positive antiretroviral-naive persons
    R D MacArthur
    Department of Medicine, Division of Infectious Diseases, Wayne State University, Detroit, Michigan 48201, USA
    HIV Clin Trials 5:361-70. 2004
    ....
  9. ncbi request reprint Adequacy of early empiric antibiotic treatment and survival in severe sepsis: experience from the MONARCS trial
    Rodger D MacArthur
    Wayne State University, Detroit, Michigan 48201, USA
    Clin Infect Dis 38:284-8. 2004
    ..001). We conclude that adequate antibiotic therapy results in a significant decrease in the crude mortality rate among patients suspected of sepsis...
  10. ncbi request reprint The rationale and design of the CPCRA (Terry Beirn Community Programs for Clinical Research on AIDS) 058 FIRST (Flexible Initial Retrovirus Suppressive Therapies) trial
    R D MacArthur
    University Health Center, Wayne State University, 4201 St Antoine, UHC 7 D, Detroit, MI 48201, USA
    Control Clin Trials 22:176-90. 2001
    ..This article presents the study design, discusses the challenges we have faced in implementing the trial, and describes our preliminary experiences. Control Clin Trials 2001;22:176-190..
  11. ncbi request reprint An updated guide to genotype interpretation
    Rodger D MacArthur
    Division of Infectious Diseases, Wayne State University School of Medicine, Detroit, Michigan, USA
    AIDS Read 14:256-8, 261-4, 266. 2004
    ..This report gives an update about important new developments in the area of antiretroviral resistance and provides a guide to interpreting genotype reports...
  12. ncbi request reprint The effects of massage therapy alone and in combination with other complementary therapies on immune system measures and quality of life in human immunodeficiency virus
    T J Birk
    Department of Physical Therapy, College of Pharmacy and Allied Health, Wayne State University and Rehabilitation Institute of Michigan, Detroit 48207, USA
    J Altern Complement Med 6:405-14. 2000
    ....
  13. ncbi request reprint A self-learning fuzzy discrete event system for HIV/AIDS treatment regimen selection
    Hao Ying
    Department of Electrical and Computer Engineering, Wayne State University, Detroit, MI 48202, USA
    IEEE Trans Syst Man Cybern B Cybern 37:966-79. 2007
    ..This learning and prediction approach, as well as our original FDESs theory, is general purpose and can be applied to other medical or nonmedical problems...
  14. doi request reprint Mild-to-moderate symptoms during the first year of antiretroviral therapy worsen quality of life in HIV-infected individuals
    Sharon B Mannheimer
    Division of Infectious Diseases, Harlem Hospital Center, New York, New York, USA
    Clin Infect Dis 46:941-5. 2008
    ..Quality of life was inversely related to the number of symptoms and in the change in the number of symptoms from baseline...
  15. ncbi request reprint A fuzzy discrete event system approach to determining optimal HIV/AIDS treatment regimens
    Hao Ying
    Department of Electrical and Computer Engineering, Wayne State University, Detroit, MI 48202, USA
    IEEE Trans Inf Technol Biomed 10:663-76. 2006
    ..These are practically important features to medical applications in general, and HIV/AIDS treatment in particular, as national HIV/AIDS treatment guidelines are modified several times per year...
  16. ncbi request reprint Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody F(ab')2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels
    Edward A Panacek
    Department of Medicine, University of California Davis Medical Center, Sacramento, CA, USA
    Crit Care Med 32:2173-82. 2004
    ..To evaluate whether administration of afelimomab, an anti-tumor necrosis factor F(ab')2 monoclonal antibody fragment, would reduce 28-day all-cause mortality in patients with severe sepsis and elevated serum levels of IL-6...
  17. ncbi request reprint A comparison of three highly active antiretroviral treatment strategies consisting of non-nucleoside reverse transcriptase inhibitors, protease inhibitors, or both in the presence of nucleoside reverse transcriptase inhibitors as initial therapy (CPCRA 05
    Rodger D MacArthur
    Wayne State University, Detroit, MI, USA
    Lancet 368:2125-35. 2006
    ..Here, we report results from the FIRST trial, which compared initial treatment strategies for clinical, immunological, and virological outcomes...
  18. ncbi request reprint Effects of Mycobacterium avium complex-infection treatment on cytokine expression in human immunodeficiency virus-infected persons: results of AIDS clinical trials group protocol 853
    R D MacArthur
    Wayne State University, Department of Medicine, Division of Infectious Diseases, Detroit, MI 48201, USA
    J Infect Dis 181:1486-90. 2000
    ..Nonsignificant decreases in plasma levels of TNF-alpha, IL-1beta, IL-6, and HIV RNA were also seen in those individuals who remained on stable antiretroviral therapy throughout the 8 weeks of the study...
  19. pmc Discordance between viral loads determined by Roche COBAS AMPLICOR human immunodeficiency virus type 1 monitor (version 1.5) Standard and ultrasensitive assays caused by freezing patient plasma in centrifuged becton-dickinson vacutainer brand plasma prepa
    Hossein Salimnia
    Department of Pathology, Detroit, MI 48201, USA
    J Clin Microbiol 43:4635-9. 2005
    ..If the plasma was transferred from the centrifuged plasma preparation tubes before freezing, standard and ultrasensitive results were concordant with each other and with values determined on plasma from lavender-topped EDTA tubes...
  20. ncbi request reprint Aerobic exercise training fails to lower hypertriglyceridemia levels in persons with advanced HIV-1 infection
    Thomas J Birk
    Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan, USA
    J Assoc Nurses AIDS Care 13:20-4. 2002
    ..The results suggest that long-term exercise training cannot correct lipid profile abnormality, particularly hypertriglyceridemia, common to individuals with advanced HIV-1 infection...
  21. ncbi request reprint Multicenter evaluation of a human monoclonal antibody to Enterobacteriaceae common antigen in patients with Gram-negative sepsis
    Timothy E Albertson
    Department of Medicine, University of California, Davis, Sacramento, USA
    Crit Care Med 31:419-27. 2003
    ....
  22. ncbi request reprint Acetylator phenotype and genotype in HIV-infected patients with and without sulfonamide hypersensitivity
    William M O'Neil
    Department of Pharmaceutical Sciences, Wayne State University, Detroit, Michigan 48202, USA
    J Clin Pharmacol 42:613-9. 2002
    ....
  23. ncbi request reprint Repair type I aortic dissection in a patient with human immunodeficiency virus infection
    Frank A Baciewicz
    Department of Cardiothoracic Surgery, Harper University Hospital, Wayne State University, Detroit, Michigan 48201, USA
    Ann Thorac Surg 76:917-9. 2003
    ..The thoracic and abdominal aorta diameters have remained stable. Select patients with type I aortic dissection and HIV infection are candidates for surgical repair...
  24. ncbi request reprint Prevalence and impact of HIV-1 protease codon 33 mutations and polymorphisms in treatment-naive and treatment-experienced patients
    Michael J Kozal
    Yale University Et VA CT Healthcare System, New Haven, CT, USA
    Antivir Ther 11:457-63. 2006
    ..Little is known about the difference in prevalence of codon 33 mutations and polymorphisms between treatment-naive and treatment-experienced patients, and the effect of codon 33F on PI phenotypic resistance patterns...
  25. ncbi request reprint A randomized clinical trial comparing nelfinavir and ritonavir in patients with advanced HIV disease (CPCRA 042/CTN 102)
    George Perez
    North Jersey Community Research Initiative, Newark, NJ 07103, USA
    HIV Clin Trials 5:7-18. 2004
    ..To compare the long-term clinical efficacy and toxicity of initial strategies of nelfinavir (NFV) or ritonavir (RTV) in patients with CD4+ cells below 200/mm3...
  26. ncbi request reprint Prevalence of antiretroviral drug resistance mutations in chronically HIV-infected, treatment-naive patients: implications for routine resistance screening before initiation of antiretroviral therapy
    Richard M Novak
    University of Illinois, Chicago, IL 60612, USA
    Clin Infect Dis 40:468-74. 2005
    ..However, it is unclear to what extent these mutations persist in chronically infected, treatment-naive patients...
  27. pmc Episodic antiretroviral therapy increases HIV transmission risk compared with continuous therapy: results of a randomized controlled trial
    William Burman
    Denver Public Health, 605 Bannock Street, Denver, CO 80204, USA
    J Acquir Immune Defic Syndr 49:142-50. 2008
    ..To compare the HIV transmission risk among patients randomized to episodic versus continuous antiretroviral therapy...
  28. pmc Poor initial CD4+ recovery with antiretroviral therapy prolongs immune depletion and increases risk for AIDS and non-AIDS diseases
    Jason V Baker
    Department of Biostatistics, University of Minnesota, Minneapolis, MN, USA
    J Acquir Immune Defic Syndr 48:541-6. 2008
    ..Low CD4+ increases risk for both AIDS- and non-AIDS-related morbidity and mortality. The magnitude of CD4+ recovery early after initial antiretroviral therapy (ART) is important in the ultimate duration of immune depletion...
  29. pmc CD4+ count and risk of non-AIDS diseases following initial treatment for HIV infection
    Jason V Baker
    University of Minnesota, Minneapolis, USA
    AIDS 22:841-8. 2008
    ..Reductions in AIDS-related morbidity and mortality following the advent of combination antiretroviral therapy have coincided with relative increases in chronic non-AIDS end-organ diseases among HIV+ patients...
  30. pmc Differential adherence to combination antiretroviral therapy is associated with virological failure with resistance
    Edward M Gardner
    Denver Public Health, Denver, Colorado 80204, USA
    AIDS 22:75-82. 2008
    ..To investigate the occurrence of differential adherence to components of combination antiretroviral therapy and assess its predictors and association with virological failure and antiretroviral medication resistance...
  31. ncbi request reprint The Incidence of HIV drug resistance and its impact on progression of HIV disease among antiretroviral-naïve participants started on three different antiretroviral therapy strategies
    Michael J Kozal
    Yale University School of Medicine and VA CT Healthcare System, New Haven, Connecticut 06510, USA
    HIV Clin Trials 8:357-70. 2007
    ..The strategies were compared for drug resistance at first virologic failure (VF; HIV RNA >1000 copies/mL). The impact of resistance on AIDS or death was determined...
  32. ncbi request reprint Beta-glucuronidase activity in patients infected with HIV
    William M O'Neil
    AIDS 17:269-70. 2003
  33. ncbi request reprint Antibody to enterobacterial common antigen and gram-negative sepsis
    Paul Bayardelle
    Crit Care Med 32:617-8. 2004