Sanjeev Kumar

Summary

Affiliation: Wayne State University
Country: USA

Publications

  1. pmc Ritonavir blocks AKT signaling, activates apoptosis and inhibits migration and invasion in ovarian cancer cells
    Sanjeev Kumar
    Laboratory of Surgical Oncology and Developmental Therapeutics, Department of Surgery, Wayne State University, Detroit, MI, USA
    Mol Cancer 8:26. 2009
  2. doi request reprint Second neoplasms in survivors of endometrial cancer: impact of radiation therapy
    Sanjeev Kumar
    Department of Obstetrics and Gynecology, Wayne State University School of Medicine and Karmanos Cancer Institute, Detroit, MI 48201, USA
    Gynecol Oncol 113:233-9. 2009
  3. doi request reprint Radiation-associated endometrial cancer
    Sanjeev Kumar
    Departments of Obstetrics and Gynecology, Division of Gynecologic Oncology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    Obstet Gynecol 113:319-25. 2009
  4. doi request reprint A comparison of younger vs older women with vulvar cancer in the United States
    Sanjeev Kumar
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Am J Obstet Gynecol 200:e52-5. 2009
  5. doi request reprint Prognostic significance of keratinization in squamous cell cancer of uterine cervix: a population based study
    Sanjeev Kumar
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, School of Medicine, Hutzel Women s Hospital, Wayne State University, 3990 John R, 7 Brush North, Detroit, MI 48201, USA
    Arch Gynecol Obstet 280:25-32. 2009
  6. doi request reprint The prevalence and prognostic impact of lymph node metastasis in malignant germ cell tumors of the ovary
    Sanjeev Kumar
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Wayne State University School of Medicine Detroit, Michigan 48201, USA
    Gynecol Oncol 110:125-32. 2008
  7. pmc Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells
    Christopher S Bryant
    Department of Surgery, Wayne State University, 4100 John R Street, Detroit, MI 48201, USA
    Mol Cancer 9:47. 2010
  8. doi request reprint MicroRNA-101 inhibits growth of epithelial ovarian cancer by relieving chromatin-mediated transcriptional repression of p21(waf¹/cip¹)
    Assaad Semaan
    Laboratory of Surgical Oncology and Developmental Therapeutics Department of Surgery, Wayne State University, Detroit, Michigan 48201, USA
    Pharm Res 28:3079-90. 2011
  9. doi request reprint The prognostic impact of the ratio of positive lymph nodes on survival of epithelial ovarian cancer patients
    Haider Mahdi
    Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington, USA
    J Surg Oncol 103:724-9. 2011
  10. doi request reprint Expression of GLUT-1 in epithelial ovarian carcinoma: correlation with tumor cell proliferation, angiogenesis, survival and ability to predict optimal cytoreduction
    Assaad Semaan
    Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Gynecol Oncol 121:181-6. 2011

Collaborators

Detail Information

Publications35

  1. pmc Ritonavir blocks AKT signaling, activates apoptosis and inhibits migration and invasion in ovarian cancer cells
    Sanjeev Kumar
    Laboratory of Surgical Oncology and Developmental Therapeutics, Department of Surgery, Wayne State University, Detroit, MI, USA
    Mol Cancer 8:26. 2009
    ..Recent observations point to a lower incidence of some cancers in patients treated with protease inhibitor (PI) cocktail treatment known as HAART (Highly Active Anti-Retroviral Therapy)...
  2. doi request reprint Second neoplasms in survivors of endometrial cancer: impact of radiation therapy
    Sanjeev Kumar
    Department of Obstetrics and Gynecology, Wayne State University School of Medicine and Karmanos Cancer Institute, Detroit, MI 48201, USA
    Gynecol Oncol 113:233-9. 2009
    ..To evaluate the association of radiotherapy to subsequent second cancers in endometrial carcinoma survivors...
  3. doi request reprint Radiation-associated endometrial cancer
    Sanjeev Kumar
    Departments of Obstetrics and Gynecology, Division of Gynecologic Oncology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    Obstet Gynecol 113:319-25. 2009
    ..To compare prognostic variables and survival of radiation-associated endometrial cancers with sporadic second endometrial cancers...
  4. doi request reprint A comparison of younger vs older women with vulvar cancer in the United States
    Sanjeev Kumar
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Am J Obstet Gynecol 200:e52-5. 2009
    ..The purpose of this study was to compare the prognostic variables and survival of younger (< 50 years) to that of older (> or = 50 years) women with vulvar cancer...
  5. doi request reprint Prognostic significance of keratinization in squamous cell cancer of uterine cervix: a population based study
    Sanjeev Kumar
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, School of Medicine, Hutzel Women s Hospital, Wayne State University, 3990 John R, 7 Brush North, Detroit, MI 48201, USA
    Arch Gynecol Obstet 280:25-32. 2009
    ..To determine the influence of keratinization on prognosis in squamous cell cancer (SCC) of the uterine cervix...
  6. doi request reprint The prevalence and prognostic impact of lymph node metastasis in malignant germ cell tumors of the ovary
    Sanjeev Kumar
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Wayne State University School of Medicine Detroit, Michigan 48201, USA
    Gynecol Oncol 110:125-32. 2008
    ..The purpose of this study is to report the prevalence and prognostic importance of lymph node metastasis in malignant germ cell tumors of the ovary (OGCT)...
  7. pmc Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells
    Christopher S Bryant
    Department of Surgery, Wayne State University, 4100 John R Street, Detroit, MI 48201, USA
    Mol Cancer 9:47. 2010
    ..The aim of this study is to understand the signaling mechanisms through which SFN influences the cell growth and proliferation in EOC...
  8. doi request reprint MicroRNA-101 inhibits growth of epithelial ovarian cancer by relieving chromatin-mediated transcriptional repression of p21(waf¹/cip¹)
    Assaad Semaan
    Laboratory of Surgical Oncology and Developmental Therapeutics Department of Surgery, Wayne State University, Detroit, Michigan 48201, USA
    Pharm Res 28:3079-90. 2011
    ..Enhancer of zeste homolog 2 (EzH2) appears to be a functional target of miR-101. We explore the role of miR-101 and its interaction with EzH2 in epithelial ovarian carcinoma (EOC)...
  9. doi request reprint The prognostic impact of the ratio of positive lymph nodes on survival of epithelial ovarian cancer patients
    Haider Mahdi
    Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington, USA
    J Surg Oncol 103:724-9. 2011
    ..To study the prognostic significance of ratio of positive to examined lymph nodes (LNR) on survival of patients with node positive epithelial ovarian cancer (NPEOC)...
  10. doi request reprint Expression of GLUT-1 in epithelial ovarian carcinoma: correlation with tumor cell proliferation, angiogenesis, survival and ability to predict optimal cytoreduction
    Assaad Semaan
    Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Gynecol Oncol 121:181-6. 2011
    ..GLUT-1 is involved at various steps in the processes of tumor progression. The objective of this study was to examine the relationship between GLUT-1 expression and tumor proliferation and angiogenesis in epithelial ovarian carcinoma...
  11. doi request reprint EZH2 blockade by RNA interference inhibits growth of ovarian cancer by facilitating re-expression of p21(waf1/cip1) and by inhibiting mutant p53
    Shelly Seward
    Laboratory of Surgical Oncology and Developmental Therapeutics, Department of Surgery, Wayne State University, Detroit, MI 48201, USA
    Cancer Lett 336:53-60. 2013
    ..Further, silencing of EZH2 resulted in re-expression of p21(waf1/cip1) and down-regulation of mutant p53. Finally, EZH2 knockdown contributed to attenuated EOC growth in SCID mice...
  12. doi request reprint Prognostic impact of marital status on survival of women with epithelial ovarian cancer
    Haider Mahdi
    Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA, USA
    Psychooncology 22:83-8. 2013
    ..The objective of this study is to examine the impact of marital status on survival of patients with epithelial ovarian cancer (EOC)...
  13. doi request reprint Validation of tumor size as staging variable in the revised International Federation of Gynecology and Obstetrics stage I leiomyosarcoma: a population-based study
    Gunjal Garg
    Department of Obstetrics and Gynecology, Detroit Medical Center, Detroit, MI, USA
    Int J Gynecol Cancer 20:1201-6. 2010
    ..In this large population-based study, we validate the use of tumor size for purposes of risk stratification among stage I leiomyosarcoma patients...
  14. doi request reprint Disparities in treatment and survival between African American and White women with vaginal cancer
    Haider Mahdi
    Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA, USA
    Gynecol Oncol 122:38-41. 2011
    ..The study aims to compare the difference in treatment and survival between White (W) and African American (AA) patients with vaginal cancer (VC)...
  15. doi request reprint Prognostic analysis of ovarian cancer associated with endometriosis
    Sanjeev Kumar
    Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI, USA
    Am J Obstet Gynecol 204:63.e1-7. 2011
    ..The objective of the study was to evaluate the prognosis of ovarian cancer arising in endometriosis...
  16. ncbi request reprint Racial disparity in the clinical determinants and outcomes of cesarean hysterectomy
    Anthony N Imudia
    Department of Obstetrics and Gynecology, Wayne State University School of Medicine Detroit Medical Center, Detroit, Michigan 48201, USA
    J Natl Med Assoc 101:565-8. 2009
    ..In conclusion, beyond higher rates of cardiopulmonary complications and urological injury among whites, no significant racial differences exist in the risk factors, indications for, and complications from cesarean hysterectomy...
  17. doi request reprint Racial disparities in survival among patients with germ cell tumors of the ovary--United States
    Christopher S Bryant
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Wayne State University School of Medicine, Detroit, MI, USA
    Gynecol Oncol 114:437-41. 2009
    ..To compare the survival of African American (AA) and white (W) patients with malignant germ cell tumors of the ovary (OGCT)...
  18. doi request reprint Lymphadenectomy and ovarian preservation in low-grade endometrial stromal sarcoma
    Jay P Shah
    Division of Gynecology Oncology, Department of Pathology, Wayne State University and Karmanos Cancer Center, Detroit, Michigan 48201, USA
    Obstet Gynecol 112:1102-8. 2008
    ..To report the impact on overall survival of lymphadenectomy and ovarian preservation in patients with endometrial stromal sarcoma...
  19. doi request reprint Therapy-related myeloid leukemia after treatment for epithelial ovarian carcinoma: an epidemiological analysis
    Agnieszka Vay
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Wayne State University, Detroit, MI 48201, USA
    Gynecol Oncol 123:456-60. 2011
    ..This study examines the incidence, characteristics and clinical outcomes of patients who developed secondary myeloid-type leukemia after a diagnosis of EOC...
  20. doi request reprint Feasibility of extension of platinum-free interval with weekly bolus topotecan and subsequent platinum retreatment outcomes in recurrent ovarian cancer
    Christopher S Bryant
    Wayne State University, Barbara Ann Karmanos Cancer Institute, Harper Professional Building, Detroit, MI, 48201, USA
    Arch Gynecol Obstet 283:361-7. 2011
    ....
  21. doi request reprint Prognostic impact of laterality in malignant ovarian germ cell tumors
    Haider Mahdi
    Department of Obstetrics and Gynecology, University of Washington, Seattle, WA, USA
    Int J Gynecol Cancer 21:257-62. 2011
    ..To compare the survival of patients with bilateral versus unilateral malignant ovarian germ cell tumors (OGCT)...
  22. doi request reprint Suicide in women with gynecologic cancer
    Haider Mahdi
    Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA, USA
    Gynecol Oncol 122:344-9. 2011
    ..To characterize the suicide rates among patients with gynecologic cancer in the Unites States and to identify factors associated with high suicide rates...
  23. doi request reprint Ovarian and uterine carcinosarcomas: a comparative analysis of prognostic variables and survival outcomes
    Gunjal Garg
    Department of Obstetrics and Gynecology, Detroit Medical Center, Detroit, MI 48201, USA
    Int J Gynecol Cancer 20:888-94. 2010
    ..The objective of this study was to identify site-specific differences by comparing carcinosarcomas originating in the uterus and the ovaries...
  24. doi request reprint A population-based analysis of 788 cases of yolk sac tumors: A comparison of males and females
    Jay P Shah
    Division of Gynecology Oncology, Wayne State University and Karmanos Cancer Center, Detroit, MI, USA
    Int J Cancer 123:2671-5. 2008
    ..Although the overall survival in all YST patients has improved over the past few decades, the primary sites of origin differ in males and females and impact prognosis...
  25. doi request reprint Reduction of hypoxia-induced angiogenesis in ovarian cancer cells by inhibition of HIF-1 alpha gene expression
    Christopher S Bryant
    Division of Gynecologic Oncology, Barbara Ann Karmanos Cancer Institute, Wayne State University, Harper Professional Building, 4160 John R Street, Detroit, MI 48201, USA
    Arch Gynecol Obstet 282:677-83. 2010
    ..The goal of this study was to investigate the effects of silencing HIF-1 alpha gene expression with specific small interfering RNA (siRNA) on VEGF production and angiogenesis in epithelial ovarian cancer (EOC) cells...
  26. ncbi request reprint Successful pregnancy after fertility-sparing surgery for peritoneal psammocarcinoma: a case report
    Jay P Shah
    Division of Gynecologic Oncology, Wayne State University, Detroit, Michigan, USA
    J Reprod Med 54:179-83. 2009
    ..Psammocarcinoma is a rare form of low grade serous carcinoma of the ovary or peritoneum. Although limited to case reports and small series, psammocarcinoma appears to have an indolent course...
  27. doi request reprint Impact of microsatellite instability (MSI) on survival in high grade endometrial carcinoma
    Haitham Arabi
    Department of Pathology, Wayne State University, Detroit, MI 48201, USA
    Gynecol Oncol 113:153-8. 2009
    ..The goal of this study is to identify the correlation between MSI and clinicopathologic markers along with survival in high grade endometrial carcinoma EC...
  28. pmc Life-threatening clostridial sepsis in a postmenopausal patient with degenerating uterine leiomyoma
    Christopher S Bryant
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA
    Case Report Med 2010:541959. 2010
    ..Fortunately, C. perfringens-associated sepsis and death in the gynecologic patient is rarely encountered. We report a case of intrauterine C. perfringens presenting as life-threatening sepsis in a postmenopausal patient...
  29. pmc Transcervical retrieval of fetal cells in the practice of modern medicine: a review of the current literature and future direction
    Anthony N Imudia
    Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI 48201 1405, USA
    Fertil Steril 93:1725-30. 2010
    ..To review published methods for transcervical collection of fetal cells and to assess the potential of this approach for application in prenatal diagnosis...
  30. doi request reprint Incidence, trends, risk factors, indications for, and complications associated with cesarean hysterectomy: a 17-year experience from a single institution
    Anthony N Imudia
    Department of Obstetrics and Gynecology, Hutzel Women s Hospital, Wayne State University School of Medicine Detroit Medical Center, 3980 John R, 7 Brush North, Detroit, MI 48201, USA
    Arch Gynecol Obstet 280:619-23. 2009
    ..To review the incidence, trends, risk factors, indications for, and complications associated with cesarean hysterectomy (CH) in our institution...
  31. doi request reprint Pathogenesis of Intra-abdominal and pelvic adhesion development
    Anthony N Imudia
    Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, Detroit, Michigan, USA
    Semin Reprod Med 26:289-97. 2008
    ..Greater understanding of the regulation and interaction of these processes provides the potential for reduction of postoperative adhesion development...
  32. ncbi request reprint Women emerge from general anesthesia faster than men
    Pramila Bajaj
    Department of Anaesthesiology and Critical Care, R N T Medical College and Associated Group of Hospitals, Udaipur Rajasthan 313004, India
    Middle East J Anesthesiol 19:173-83. 2007
    ..Investigators have noted that normal differences account for changes in function of the GABA receptor known to be important in the action of many anesthetics...
  33. ncbi request reprint Anti-inflammatory effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors (statins) in peritoneal dialysis patients
    Sanjeev Kumar
    Nephrology and Transplantation, Barts and The London NHS Trust, Whitechapel, London, United Kingdom
    Perit Dial Int 27:283-7. 2007
    ..Statins have been demonstrated to have anti-inflammatory properties by virtue of their CRP lowering effects in hemodialysis patients. However, whether statins have an anti-inflammatory effect in PD patients is unknown...
  34. ncbi request reprint Comparison of the relation between renal impairment, angiographic coronary artery disease, and long-term mortality in women versus men
    Ruoling Chen
    Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, United Kingdom
    Am J Cardiol 97:630-2. 2006
    ..Gender may influence the prognostic effect of renal impairment in coronary disease...
  35. ncbi request reprint Cystosarcoma phyllodes: our institutional experience
    Sanjeev C Joshi
    Department of Radiation Oncology, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi, India
    Australas Radiol 47:434-7. 2003
    ..Four patients received postoperative radiotherapy. Median follow-up period was 35 months. Six patients showed recurrence, and four of these were malignant. Median disease-free survival period was 34 months...