Ikuko Kato

Summary

Affiliation: Wayne State University
Country: USA

Publications

  1. pmc APOE and FABP2 Polymorphisms and History of Myocardial Infarction, Stroke, Diabetes, and Gallbladder Disease
    Ikuko Kato
    Karmanos Cancer Institute, School of Medicine, Wayne State University, 4100 John R Street, Detroit, MI 48201, USA
    Cholesterol 2011:896360. 2011
  2. pmc Partial associations of dietary iron, smoking and intestinal bacteria with colorectal cancer risk
    Ikuko Kato
    Karmanos Cancer Institute, and Department of Pathology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    Nutr Cancer 65:169-77. 2013
  3. pmc Pesticide product use and risk of non-Hodgkin lymphoma in women
    Ikuko Kato
    Department of Environmental Medicine, New York University of School of Medicine, New York, New York, USA
    Environ Health Perspect 112:1275-81. 2004
  4. ncbi request reprint Patterns of cancer in first generation immigrants from the Arab League and other countries
    Ikuko Kato
    Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA
    J Registry Manag 36:71-6; quiz 101-2. 2009
  5. ncbi request reprint Does use of alternative medicine delay treatment of head and neck cancer? A surveillance, epidemiology, and end results (SEER) cancer registry study
    Ikuko Kato
    Karmanos Cancer Institute, Wayne State University School of Medicine, 110 E Warren Avenue, Detroit, Michigan, USA
    Head Neck 30:446-54. 2008
  6. ncbi request reprint Nutritional predictors for cellular nipple aspirate fluid: Nutrition and Breast Health Study
    Ikuko Kato
    Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA
    Breast Cancer Res Treat 97:33-9. 2006
  7. ncbi request reprint Personal and occupational exposure to organic solvents and risk of non-Hodgkin's lymphoma (NHL) in women (United States)
    Ikuko Kato
    Department of Environmental Medicine, New York University of School of Medicine, New York, NY, USA
    Cancer Causes Control 16:1215-24. 2005
  8. pmc African American-preponderant single nucleotide polymorphisms (SNPs) and risk of breast cancer
    Ikuko Kato
    Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Cancer Epidemiol 33:24-30. 2009
  9. ncbi request reprint Smoking and other personal characteristics as potential predictors for fecal bacteria populations in humans
    Ikuko Kato
    Karmanos Cancer Institute, Detroit, MI, USA
    Med Sci Monit 16:CR1-7. 2010
  10. ncbi request reprint DNA/RNA markers for colorectal cancer risk in preserved stool specimens: a pilot study
    Ikuko Kato
    Karmanos Cancer Institute, Wayne State University, 110 East Warren Avenue, Detroit, MI 48201, USA
    Tumori 95:753-61. 2009

Research Grants

Collaborators

Detail Information

Publications44

  1. pmc APOE and FABP2 Polymorphisms and History of Myocardial Infarction, Stroke, Diabetes, and Gallbladder Disease
    Ikuko Kato
    Karmanos Cancer Institute, School of Medicine, Wayne State University, 4100 John R Street, Detroit, MI 48201, USA
    Cholesterol 2011:896360. 2011
    ..FABP2-T54 allele may be a potential genetic marker for myocardial infarction, and APOE4 may exert sex-dependent effects on myocardial infarction and gallbladder disease...
  2. pmc Partial associations of dietary iron, smoking and intestinal bacteria with colorectal cancer risk
    Ikuko Kato
    Karmanos Cancer Institute, and Department of Pathology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    Nutr Cancer 65:169-77. 2013
    ..93 vs. 2.23) (P = 0.014) and U.S. samples (6.65 vs. 4.37) (P < 0.001). Potential roles of iron from cigarette smoking and dietary heme in CRC through altering irontrophic luminal bacterial population may warrant further investigation...
  3. pmc Pesticide product use and risk of non-Hodgkin lymphoma in women
    Ikuko Kato
    Department of Environmental Medicine, New York University of School of Medicine, New York, New York, USA
    Environ Health Perspect 112:1275-81. 2004
    ....
  4. ncbi request reprint Patterns of cancer in first generation immigrants from the Arab League and other countries
    Ikuko Kato
    Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA
    J Registry Manag 36:71-6; quiz 101-2. 2009
    ..33). These patterns were similar for the other immigrants; however, ovary and brain were Arabic-specific, and thus may deserve further investigation for specific environmental or genetic exposures among Arabic immigrants...
  5. ncbi request reprint Does use of alternative medicine delay treatment of head and neck cancer? A surveillance, epidemiology, and end results (SEER) cancer registry study
    Ikuko Kato
    Karmanos Cancer Institute, Wayne State University School of Medicine, 110 E Warren Avenue, Detroit, Michigan, USA
    Head Neck 30:446-54. 2008
    ..The aim of the study was to assess whether CAM use was associated with a delay in the initiation of conventional cancer treatment for head and neck cancer...
  6. ncbi request reprint Nutritional predictors for cellular nipple aspirate fluid: Nutrition and Breast Health Study
    Ikuko Kato
    Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA
    Breast Cancer Res Treat 97:33-9. 2006
    ..17 (95% CI 0.04-0.65) and 0.19 (95% CI 0.04-0.91), respectively. These results are generally in support of roles of nutritional factors in breast cancer and thus further studies are warranted...
  7. ncbi request reprint Personal and occupational exposure to organic solvents and risk of non-Hodgkin's lymphoma (NHL) in women (United States)
    Ikuko Kato
    Department of Environmental Medicine, New York University of School of Medicine, New York, NY, USA
    Cancer Causes Control 16:1215-24. 2005
    ..The authors assessed whether home and occupational exposure to organic solvents is associated with risk of NHL in women...
  8. pmc African American-preponderant single nucleotide polymorphisms (SNPs) and risk of breast cancer
    Ikuko Kato
    Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Cancer Epidemiol 33:24-30. 2009
    ....
  9. ncbi request reprint Smoking and other personal characteristics as potential predictors for fecal bacteria populations in humans
    Ikuko Kato
    Karmanos Cancer Institute, Detroit, MI, USA
    Med Sci Monit 16:CR1-7. 2010
    ....
  10. ncbi request reprint DNA/RNA markers for colorectal cancer risk in preserved stool specimens: a pilot study
    Ikuko Kato
    Karmanos Cancer Institute, Wayne State University, 110 East Warren Avenue, Detroit, MI 48201, USA
    Tumori 95:753-61. 2009
    ..This pilot study investigated the feasibility of determining DNA methylation and RNA expression simultaneously in stool specimens treated with a single type of nucleic acid preservatives...
  11. ncbi request reprint Conditional median survival of patients with advanced carcinoma: surveillance, epidemiology, and end results data
    I Kato
    Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan 48201, USA
    Cancer 92:2211-9. 2001
    ..However, there are no published data on the conditional median survival of patients with advanced carcinoma on a population basis...
  12. ncbi request reprint Use of anti-inflammatory and non-narcotic analgesic drugs and risk of non-Hodgkin's lymphoma (NHL) (United States)
    Ikuko Kato
    Department of Environmental Medicine, New York University of School of Medicine, New York, NY, USA
    Cancer Causes Control 13:965-74. 2002
    ..To examine whether exposures to anti-inflammatory and non-narcotic analgesic drugs are associated with risk of non-Hodgkin's lymphoma (NHL)...
  13. ncbi request reprint Genotype-phenotype analysis for the polymorphic CA repeat in the insulin-like growth factor-I (IGF-I) gene
    I Kato
    Karmanos Cancer Institute Department of Pathology Wayne State University, Detroit, Michigan 48201, USA
    Eur J Epidemiol 18:203-9. 2003
    ..Opposite trends observed in gender and racial subgroups, i.e., an inverse association between plasma IGF-I levels and the CA repeat length in white women and a positive association in black men, are likely to be chance findings...
  14. pmc Functional polymorphisms to modulate luminal lipid exposure and risk of colorectal cancer
    Ikuko Kato
    Karmanos Cancer Institute, Wayne State University School of Medicine, 110 East Warren Avenue, Detroit, MI 48201, USA
    Cancer Epidemiol 34:291-7. 2010
    ..Fat absorption may play a crucial role in colorectal carcinogenesis by determining intra-colonic exposure to potentially carcinogenic lipid metabolites...
  15. ncbi request reprint Genetic polymorphisms in anti-inflammatory cytokine signaling and the prevalence of gastric precancerous lesions in Venezuela
    Ikuko Kato
    Karmanos Cancer Institute, 110 East Warren Avenue, Detroit, MI, 48201, USA
    Cancer Causes Control 17:1183-91. 2006
    ..The aim of the study was to assess the effects of genetic polymorphisms in anti-inflammatory mediators, i.e., IL10, IL4 and IL4R on the prevalence of gastric precancerous lesions and their interactions with other environmental factors...
  16. ncbi request reprint Polymorphisms in genes related to bacterial lipopolysaccharide/peptidoglycan signaling and gastric precancerous lesions in a population at high risk for gastric cancer
    Ikuko Kato
    Karmanos Cancer Institute, 110 East Warren Avenue, Detroit, Michigan 48201, USA
    Dig Dis Sci 52:254-61. 2007
    ..These results suggest that genetic polymorphisms in HP LPS signaling may be implicated in the development of intermediate stages of gastric premalignant lesions...
  17. ncbi request reprint History of antibiotic use and risk of non-Hodgkin's lymphoma (NHL)
    Ikuko Kato
    Department of Environmental Medicine, New York University of School of Medicine, New York, NY, USA
    Int J Cancer 107:99-105. 2003
    ..However, a direct role of antibiotics in NHL induction has not been ruled out...
  18. ncbi request reprint Host-bacterial interaction in the development of gastric precancerous lesions in a high risk population for gastric cancer in Venezuela
    Ikuko Kato
    Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA
    Int J Cancer 119:1666-71. 2006
    ..The present study provides important evidence suggesting host-bacterial interactions in the development of gastric precancerous lesions...
  19. ncbi request reprint Fecal collection, ambient preservation, and DNA extraction for PCR amplification of bacterial and human markers from human feces
    Jordan M Nechvatal
    Department of Physiology, Wayne State University, 540 E Canfield Avenue, Detroit, MI 48201, USA
    J Microbiol Methods 72:124-32. 2008
    ..Thus, fecal DNA is well preserved by methods suitable for self-collection that may be useful in future molecular epidemiological studies of intestinal bacteria and human cancer markers...
  20. pmc Characteristics and survival of head and neck cancer by HPV status: a cancer registry-based study
    Seema Sethi
    Department of Pathology, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Int J Cancer 131:1179-86. 2012
    ..To define the fraction of HNSCC preventable by HPV vaccination or amenable to less aggressive treatment, however, tobacco exposure and HPV markers other than DNA presence need to be taken into account...
  21. pmc Estrogen plus progestin and colorectal cancer incidence and mortality
    Michael S Simon
    Karmanos Cancer Institute, Wayne State University, Hudson Webber Cancer Research Building, 4221 HWCRC, 4100 John R, Detroit, MI 48201, USA
    J Clin Oncol 30:3983-90. 2012
    ..To assess the clinical relevance of the findings, analyses of the influence of combined hormone therapy on colorectal cancer incidence and colorectal cancer mortality were conducted after extended follow-up...
  22. doi request reprint Racial disparities in Human Papillomavirus (HPV) associated head and neck cancer
    Jose Jiron
    Department of Otolaryngology, Wayne State University School of Medicine, Detroit, MI, USA
    Am J Otolaryngol 35:147-53. 2014
    ..We aimed to elucidate whether racial disparities in HPV prevalence and overall survival were due to confounding from smoking or alcohol use...
  23. pmc Exfoliated cells in stool: a source for reverse transcription-PCR-based analysis of biomarkers of gastrointestinal cancer
    Ying Jie Yu
    Department of Internal Medicine, Wayne State University, Detroit, MI 48201, USA
    Cancer Epidemiol Biomarkers Prev 17:455-8. 2008
    ..Of all the preservative methods tested, RNAlater had the best performance in terms of overall quality, quantity, and level of genomic DNA contamination, and thus deserves further investigation...
  24. ncbi request reprint Postmenopausal levels of sex hormones and risk of breast carcinoma in situ: results of a prospective study
    Anne Zeleniuch-Jacquotte
    Department of Environmental Medicine, New York University School of Medicine, Room 539, 650 First Avenue, New York, NY 10016, USA
    Int J Cancer 114:323-7. 2005
    ....
  25. pmc Dietary fatty acids, luminal modifiers, and risk of colorectal cancer
    Ikuko Kato
    Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    Int J Cancer 127:942-51. 2010
    ..029 for omega-3 and 0.068 for omega-6). Our results suggest that populations with lower intake of luminal modifiers, i.e., calcium and fiber, may have differential risks of colorectal cancer associated with dietary fatty acid intake...
  26. pmc Plasma levels of resistin-like molecule beta in humans
    Andrew P Neilson
    Comprehensive Cancer Center University of Michigan, Ann Arbor, MI, USA
    Cancer Epidemiol 35:485-9. 2011
    ..In the present study, we evaluated whether RELMβ could be measured in human plasma and the influence of selected host and behavioral factors on RELMβ levels, including known risk factors for colorectal cancer...
  27. ncbi request reprint Non-steroidal anti-inflammatory drug (NSAID) use and levels of a lipid oxidation marker in plasma and nipple aspirate fluids
    Ikuko Kato
    Karmanos Cancer Institute, Detroit, MI 48201, USA
    Breast Cancer Res Treat 97:145-8. 2006
    ..These results indicate that NSAID use can result in lower levels of 15-F(2t)-isoprostane, which may have implications for the effects of NSAID use on breast cancer risk...
  28. ncbi request reprint Environmental factors in Helicobacter pylori-related gastric precancerous lesions in Venezuela
    Ikuko Kato
    Karmanos Cancer Institute Department of Pathology, Wayne State University, Detroit MI, USA
    Cancer Epidemiol Biomarkers Prev 13:468-76. 2004
    ..However, there were no inverse associations with plasma antioxidant vitamins. These findings offer important public health implications in preventing progression of HP-associated gastric precancerous lesions in high-risk populations...
  29. pmc Racial differences in colorectal cancer incidence and mortality in the Women's Health Initiative
    Michael S Simon
    Karmanos Cancer Institute, Department of Oncology, Detroit, MI, USA
    Cancer Epidemiol Biomarkers Prev 20:1368-78. 2011
    ..The women's health initiative (WHI) study sample was used to determine whether differences in CRC risk factors explain racial/ethnic differences in incidence and mortality...
  30. doi request reprint Strategy for microbiome analysis using 16S rRNA gene sequence analysis on the Illumina sequencing platform
    Jeffrey L Ram
    Department of Physiology, Wayne State University, Detroit, MI 48201 USA
    Syst Biol Reprod Med 57:162-70. 2011
    ....
  31. doi request reprint Effect of soy protein isolate supplementation on biochemical recurrence of prostate cancer after radical prostatectomy: a randomized trial
    Maarten C Bosland
    Department of Pathology, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
    JAMA 310:170-8. 2013
    ..Soy consumption has been suggested to reduce risk or recurrence of prostate cancer, but this has not been tested in a randomized trial with prostate cancer as the end point...
  32. pmc Association of dietary quercetin with reduced risk of proximal colon cancer
    Zora Djuric
    Department of Family Medicine and Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA
    Nutr Cancer 64:351-60. 2012
    ..99). These results suggest that quercetin can have disparate effects on colon cancer risk depending on whether dietary intakes of fruit or tea are high, and that quercetin had protective effects only on proximal, not distal, colon cancer...
  33. doi request reprint "Cancer sucks," and other ponderings by adolescent and young adult cancer survivors
    Brad Zebrack
    a University of Michigan School of Social Work, Ann Arbor, MI, USA
    J Psychosoc Oncol 32:1-15. 2014
    ..Struggles with health insurance and finances were evident. Findings contribute to a better understanding of AYAs' cancer treatment experiences and will inform improvements to oncology care for this population. ..
  34. pmc Comedo-DCIS is a precursor lesion for basal-like breast carcinoma: identification of a novel p63/Her2/neu expressing subgroup
    Malathy P V Shekhar
    Department of Oncology, Wayne State University, Detroit, MI, USA
    Oncotarget 4:231-41. 2013
    ....
  35. doi request reprint A novel function of HPV16-E6/E7 in epithelial-mesenchymal transition
    Young Suk Jung
    Department of Pathology, Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA
    Biochem Biophys Res Commun 435:339-44. 2013
    ..Taken together, our findings suggest HPV16 induces EMT-like processes via induction of the EMT transcription factors which may contribute to tumor progression and metastasis...
  36. ncbi request reprint Serum autoantibodies recognizing 5-hydroxymethyl-2'-deoxyuridine, an oxidized DNA base, as biomarkers of cancer risk in women
    K Frenkel
    Department of Environmental Medicine, and Kaplan Comprehensive Cancer Center, New York University Medical Center, New York 10016, USA
    Cancer Epidemiol Biomarkers Prev 7:49-57. 1998
    ..5-6 years after the initial blood donation developed breast or colorectal cancer...
  37. pmc Circulating enterolactone and risk of breast cancer: a prospective study in New York
    A Zeleniuch-Jacquotte
    Department of Environmental Medicine, New York University School of Medicine, 650 First Avenue, Room 539, New York, NY 10016, USA
    Br J Cancer 91:99-105. 2004
    ..001) and r=0.14 in cases (P=0.04)), but no correlation with oestrogens or androgens. These results do not support a protective role of circulating lignans, in the range of levels observed, in the development of breast cancer...
  38. pmc Postmenopausal levels of oestrogen, androgen, and SHBG and breast cancer: long-term results of a prospective study
    A Zeleniuch-Jacquotte
    Department of Environmental Medicine, New York University School of Medicine, 650 First Avenue, New York, NY 10016, USA
    Br J Cancer 90:153-9. 2004
    ..They also suggest that the contribution of androgens to risk is largely through their role as substrates for oestrogen production...
  39. ncbi request reprint Chemoprevention trials in men with prostate-specific antigen failure or at high risk for recurrence after radical prostatectomy: Application to efficacy assessment of soy protein
    M C Bosland
    Department of Environmental Medicine New York University School of Medicine, New York, New York 10016, USA
    Urology 57:202-4. 2001
    ..The strengths and limitations of these designs are discussed and interim experience using studies with soy protein as the intervention agent are summarized...
  40. ncbi request reprint Serum carotenoids and breast cancer
    P Toniolo
    Department of Obstetrics and Gynecology, New York University School of Medicine, New York, NY 10016, USA
    Am J Epidemiol 153:1142-7. 2001
    ....
  41. ncbi request reprint A population-based study of colorectal cancer histology in the United States, 1998-2001
    Sherri L Stewart
    Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Cancer 107:1128-41. 2006
    ..Histology is an important factor in the etiology, treatment, and prognosis of cancer. The purpose of this study was to descriptively characterize colorectal cancer (CRC) histology in the United States population...
  42. ncbi request reprint Fruits, vegetables, and colon cancer risk in a pooled analysis of 14 cohort studies
    Anita Koushik
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    J Natl Cancer Inst 99:1471-83. 2007
    ..Statistical power to examine associations by colon site has been limited in previous studies...
  43. doi request reprint Effectiveness of lidocaine infusion for status epilepticus in childhood: a retrospective multi-institutional study in Japan
    Hideji Hattori
    Department of Pediatrics, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Brain Dev 30:504-12. 2008
    ..If SE is arrested by the bolus, continuous maintenance infusion should follow; treatment should proceed to different measures when SE shows a poor response to the initial bolus of lidocaine...
  44. ncbi request reprint Dietary fiber intake and risk of colorectal cancer: a pooled analysis of prospective cohort studies
    Yikyung Park
    Department of Nutrition, Harvard School of Public Health, Boston, Mass 02115, USA
    JAMA 294:2849-57. 2005
    ..Inconsistent findings from observational studies have continued the controversy over the effects of dietary fiber on colorectal cancer...

Research Grants8

  1. Genetic Susceptibility to Infection Related Cancer
    Ikuko Kato; Fiscal Year: 2005
    ..Secondary aims include to examine histopathological correlates of these polymorphisms and to determine whether selected environmental factors modify the above associations. ..
  2. Luminal Lipid Exposure, Genetics and Colon Cancer Risk
    Ikuko Kato; Fiscal Year: 2006
    ..In addition, accumulated dietary data and biological specimens will serve as an important resource for future research on other nutrient-gene interactions. ..