Ikuko Kato

..33). These patterns were similar for the other immigrants; however, ovary and brain were Arabic-specific, and thus may deserve further investigation for specific environmental or genetic exposures among Arabic immigrants...

..The authors assessed whether home and occupational exposure to organic solvents is associated with risk of NHL in women...

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..Fat absorption may play a crucial role in colorectal carcinogenesis by determining intra-colonic exposure to potentially carcinogenic lipid metabolites...

..This pilot study investigated the feasibility of determining DNA methylation and RNA expression simultaneously in stool specimens treated with a single type of nucleic acid preservatives...

..The aim of the study was to assess whether CAM use was associated with a delay in the initiation of conventional cancer treatment for head and neck cancer...

..Opposite trends observed in gender and racial subgroups, i.e., an inverse association between plasma IGF-I levels and the CA repeat length in white women and a positive association in black men, are likely to be chance findings...

..To examine whether exposures to anti-inflammatory and non-narcotic analgesic drugs are associated with risk of non-Hodgkin's lymphoma (NHL)...

..However, there are no published data on the conditional median survival of patients with advanced carcinoma on a population basis...

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..17 (95% CI 0.04-0.65) and 0.19 (95% CI 0.04-0.91), respectively. These results are generally in support of roles of nutritional factors in breast cancer and thus further studies are warranted...

..The aim of the study was to assess the effects of genetic polymorphisms in anti-inflammatory mediators, i.e., IL10, IL4 and IL4R on the prevalence of gastric precancerous lesions and their interactions with other environmental factors...

..These results suggest that genetic polymorphisms in HP LPS signaling may be implicated in the development of intermediate stages of gastric premalignant lesions...

..However, a direct role of antibiotics in NHL induction has not been ruled out...

..Thus, fecal DNA is well preserved by methods suitable for self-collection that may be useful in future molecular epidemiological studies of intestinal bacteria and human cancer markers...

..To define the fraction of HNSCC preventable by HPV vaccination or amenable to less aggressive treatment, however, tobacco exposure and HPV markers other than DNA presence need to be taken into account...

..The present study provides important evidence suggesting host-bacterial interactions in the development of gastric precancerous lesions...

..To assess the clinical relevance of the findings, analyses of the influence of combined hormone therapy on colorectal cancer incidence and colorectal cancer mortality were conducted after extended follow-up...

..Of all the preservative methods tested, RNAlater had the best performance in terms of overall quality, quantity, and level of genomic DNA contamination, and thus deserves further investigation...

..029 for omega-3 and 0.068 for omega-6). Our results suggest that populations with lower intake of luminal modifiers, i.e., calcium and fiber, may have differential risks of colorectal cancer associated with dietary fatty acid intake...

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..However, there were no inverse associations with plasma antioxidant vitamins. These findings offer important public health implications in preventing progression of HP-associated gastric precancerous lesions in high-risk populations...

..In the present study, we evaluated whether RELMβ could be measured in human plasma and the influence of selected host and behavioral factors on RELMβ levels, including known risk factors for colorectal cancer...

..These results indicate that NSAID use can result in lower levels of 15-F(2t)-isoprostane, which may have implications for the effects of NSAID use on breast cancer risk...

..FABP2-T54 allele may be a potential genetic marker for myocardial infarction, and APOE4 may exert sex-dependent effects on myocardial infarction and gallbladder disease...

..The women's health initiative (WHI) study sample was used to determine whether differences in CRC risk factors explain racial/ethnic differences in incidence and mortality...

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..2.23) (P = 0.014) and U.S. samples (6.65 vs. 4.37) (P < 0.001). Potential roles of iron from cigarette smoking and dietary heme in CRC through altering irontrophic luminal bacterial population may warrant further investigation...

..99). These results suggest that quercetin can have disparate effects on colon cancer risk depending on whether dietary intakes of fruit or tea are high, and that quercetin had protective effects only on proximal, not distal, colon cancer...

..5-6 years after the initial blood donation developed breast or colorectal cancer...

..The strengths and limitations of these designs are discussed and interim experience using studies with soy protein as the intervention agent are summarized...

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..They also suggest that the contribution of androgens to risk is largely through their role as substrates for oestrogen production...

..001) and r=0.14 in cases (P=0.04)), but no correlation with oestrogens or androgens. These results do not support a protective role of circulating lignans, in the range of levels observed, in the development of breast cancer...

..Histology is an important factor in the etiology, treatment, and prognosis of cancer. The purpose of this study was to descriptively characterize colorectal cancer (CRC) histology in the United States population...

..Statistical power to examine associations by colon site has been limited in previous studies...

..However, after accounting for other dietary risk factors, high dietary fiber intake was not associated with a reduced risk of colorectal cancer...

..If SE is arrested by the bolus, continuous maintenance infusion should follow; treatment should proceed to different measures when SE shows a poor response to the initial bolus of lidocaine...

..Secondary aims include to examine histopathological correlates of these polymorphisms and to determine whether selected environmental factors modify the above associations. ..

..In addition, accumulated dietary data and biological specimens will serve as an important resource for future research on other nutrient-gene interactions. ..