Research Topics
| S L HendrixSummaryAffiliation: Wayne State University Country: USA Publications
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Publications
Hormone therapy: evolving conceptsSusan L Hendrix
Women s Health Initiative, Wayne State University School of Medicine, Hutzel Women s Hospital, Detroit, Michigan 48201, USA
Curr Opin Rheumatol 15:464-8. 2003..To review the medical literature published in 2002 regarding menopausal hormone therapy and its impact on clinical practice...- Effects of estrogen with and without progestin on urinary incontinenceSusan L Hendrix
Department of Obstetrics and Gynecology, Wayne State University School of Medicine Hutzel Women s Hospital, Detroit, Mich 48201, USA
JAMA 293:935-48. 2005..Menopausal hormone therapy has long been credited with many benefits beyond the indications of relieving hot flashes, night sweats, and vaginal dryness, and it is often prescribed to treat urinary incontinence (UI)... - Bilateral oophorectomy and premature menopauseSusan L Hendrix
Department of Obstetrics and Gynecology, Wayne State University School of Medicine Hutzel Women s Hospital, Detroit, Michigan 48201, USA
Am J Med 118:131-5. 2005..Intense symptoms such as hot flashes, night sweats, and insomnia will redevelop, so women should be given informed consent about the need for long-term use of HT and the greater difficulty in discontinuing therapy... - Effects of conjugated equine estrogen on stroke in the Women's Health InitiativeSusan L Hendrix
Department of Obstetrics and Gynecology, Wayne State University School of Medicine Hutzel Women s Hospital, Detroit, MI, USA
Circulation 113:2425-34. 2006..This report provides a thorough analysis of the stroke finding using the final results from the completed trial database... - Long-term use of hormone therapy for urogenital complaints: is there a role?Susan L Hendrix
Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Hutzel Women s Hospital, 4707 St Antoine, Detroit, MI 48201, USA
Med Clin North Am 87:1029-37. 2003..Better studies of older therapies and the expanded number of new choices today, with more in development and evaluation, have complicated provider and patient choices, but greatly improved the potential for effective intervention... - Primary dysmenorrhea treatment with a desogestrel-containing low-dose oral contraceptiveSusan L Hendrix
Wayne State University, Detroit, MI 48201, USA
Contraception 66:393-9. 2002..No significant change in bloating, anxiety, loneliness, weight gain, or acne was reported. The DSG/EE&EE formulation shows promise for the treatment of primary dysmenorrhea and was well tolerated by the participants in this study... - Pelvic organ prolapse in the Women's Health Initiative: gravity and graviditySusan L Hendrix
Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI 48201, USA
Am J Obstet Gynecol 186:1160-6. 2002..The purpose of this study was to describe the prevalence of and correlates for pelvic organ prolapse... - Effect of selective estrogen receptor modulators on reproductive tissues other than endometriumS L Hendrix
Department of Obstetrics and Gynecology, Wayne State University Hutzel Hospital, Detroit, Michigan 48201, USA
Ann N Y Acad Sci 949:243-50. 2001..The identification and assessment of the impact of current and future SERMs on the pelvic floor and other genital tissues will be important to understanding their potential long-term application in disease treatment and prevention... - The Women's Health Initiative estrogen plus progestin trial: the study and how it changes our practiceSusan L Hendrix
Wayne State University School of Medicine, Detroit, Mich, USA
J Am Osteopath Assoc 103:S3-5. 2003 - Use of electric blankets and association with prevalence of endometrial cancerErnest L Abel
Departments of Obstetrics and Gynecology and Psychology bDepartment of Obstetrics and Gynecology and Women s Health Initiative, Wayne State University, Detroit, Michigan, USA
Eur J Cancer Prev 16:243-50. 2007..16-1.59). Although we were unable to determine the duration of electric blanket use before diagnosis of endometrial cancer, we found that women using electric blankets for 20 years or more had a significantly higher prevalence... 
Effect of weight change on natural history of pelvic organ prolapseBela I Kudish
Department of Obstetrics and Gynecology, Washington Hospital Center, Washington, DC, USA
Obstet Gynecol 113:81-8. 2009..To evaluate the relationship between change in weight and pelvic organ prolapse (POP) progression/regression in women during a 5-year period...- Medroxyprogesterone acetate treatment of abnormal uterine bleeding: factors predicting satisfactionHolly E Richter
University of Alabama at Birmingham, Department of Obstetrics and Gynecology, Birmingham, Alabama 35249 7333, USA
Am J Obstet Gynecol 189:37-42. 2003..This study was undertaken to identify the determinants of patient satisfaction with a cyclic regimen of medroxyprogesterone acetate (MPA) for abnormal uterine bleeding... - Clinical predictors of endometritis in women with symptoms and signs of pelvic inflammatory diseaseJ F Peipert
Department of Obstetrics and Gynecology, Women and Infants Hospital, Brown University School of Medicine, Providence, Rhode Island 02905, USA
Am J Obstet Gynecol 184:856-63; discussion 863-4. 2001..The purpose of this study was to evaluate the diagnostic test characteristics of clinical criteria for the diagnosis of pelvic inflammatory disease... - Operative vaginal delivery and midline episiotomy: a bad combination for the perineumBela Kudish
Department of Obstetrics and Gynecology, Wayne State University, Detroit, MI, USA
Am J Obstet Gynecol 195:749-54. 2006..Given the reported substantial long-term adverse consequences for anal function, this combination of operative modalities should be avoided if possible... - Calcium plus vitamin D supplementation and the risk of colorectal cancerJean Wactawski-Wende
Department of Social and Preventive Medicine, University at Buffalo, 270 Farber Hall, Buffalo, NY 14214, USA
N Engl J Med 354:684-96. 2006..However, randomized-trial evidence that calcium with vitamin D supplementation is beneficial in the primary prevention of colorectal cancer is lacking... - Low-fat dietary pattern and risk of colorectal cancer: the Women's Health Initiative Randomized Controlled Dietary Modification TrialShirley A A Beresford
Department of Epidemiology, University of Washington, Seattle, WA 98195 7236, USA
JAMA 295:643-54. 2006..Observational studies and polyp recurrence trials are not conclusive regarding the effects of a low-fat dietary pattern on risk of colorectal cancer, necessitating a primary prevention trial... - Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification TrialBarbara V Howard
MedStar Research Institute Howard University, Washington, DC, USA
JAMA 295:655-66. 2006..Multiple epidemiologic studies and some trials have linked diet with cardiovascular disease (CVD) prevention, but long-term intervention data are needed... - Calcium plus vitamin D supplementation and the risk of fracturesRebecca D Jackson
Division of Endocrinology, Ohio State University, 485 McCampbell, 1581 Dodd Dr, Columbus, OH 43210, USA
N Engl J Med 354:669-83. 2006..The efficacy of calcium with vitamin D supplementation for preventing hip and other fractures in healthy postmenopausal women remains equivocal... - Effects of conjugated equine estrogens on breast cancer and mammography screening in postmenopausal women with hysterectomyMarcia L Stefanick
Stanford Prevention Research Center, Department of Medicine, Stanford University, Stanford, Calif 94305, USA
JAMA 295:1647-57. 2006..Preliminary results suggesting possible reduction in breast cancers warranted more detailed analysis... - Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trialSally A Shumaker
Department of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, NC 27104, USA
JAMA 289:2651-62. 2003..On July 8, 2002, the study drugs, estrogen plus progestin, in the Women's Health Initiative (WHI) trial were discontinued because of certain increased health risks in women receiving combined hormone therapy... - Prior hormone therapy and breast cancer risk in the Women's Health Initiative randomized trial of estrogen plus progestinGarnet L Anderson
WHI Clinical Coordinating Center, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, M3 A410, P O Box 19024, Seattle, WA 98109 1024, United States
Maturitas 55:103-15. 2006..To assess the extent to which prior hormone therapy modifies the breast cancer risk found with estrogen plus progestin (E+P) in the Women's Health Initiative (WHI) randomized trial... - Incidence of cervical cytological abnormalities with aging in the women's health initiative: a randomized controlled trialShagufta Yasmeen
Department of Obstetrics Gynecology and Internal Medicine, University of California, Davis, 95817, USA
Obstet Gynecol 108:410-9. 2006..To estimate the incidence of cytological abnormalities and cervical cancer and to determine the effect of oral estrogen and progestin on cervical cytology among postmenopausal women participating in a multi-institution clinical trial... - Urinary incontinence and menopause: an evidence-based treatment approachSusan L Hendrix
Dis Mon 48:622-36. 2002..Increasing awareness is needed by women and their providers to identify, evaluate, and apply evidence-based treatment approaches to urinary incontinence... - Low-fat dietary pattern and risk of invasive breast cancer: the Women's Health Initiative Randomized Controlled Dietary Modification TrialRoss L Prentice
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Wash 98109, USA
JAMA 295:629-42. 2006..The hypothesis that a low-fat dietary pattern can reduce breast cancer risk has existed for decades but has never been tested in a controlled intervention trial... - Effect of estrogen plus progestin on stroke in postmenopausal women: the Women's Health Initiative: a randomized trialSylvia Wassertheil-Smoller
Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
JAMA 289:2673-84. 2003..The Women's Health Initiative (WHI) trial of estrogen plus progestin was stopped early because of adverse effects, including an increased risk of stroke in the estrogen plus progestin group... - Cardiovascular disease, its risk factors and treatment, and age-related macular degeneration: Women's Health Initiative Sight Exam ancillary studyRonald Klein
Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin 53726, USA
Am J Ophthalmol 143:473-83. 2007..To examine the association of cardiovascular disease (CVD), CVD risk factors, and CVD treatment with age-related macular degeneration (AMD)... - Lipoprotein particle concentrations may explain the absence of coronary protection in the women's health initiative hormone trialsJudith Hsia
Department of Medicine, George Washington University, Washington, DC, USA
Arterioscler Thromb Vasc Biol 28:1666-71. 2008..In an effort to explain this finding, we examined lipoprotein particle concentrations and their interactions with hormone therapy in a case-control substudy... - Prevalence and correlates of panic attacks in postmenopausal women: results from an ancillary study to the Women's Health InitiativeJordan W Smoller
Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
Arch Intern Med 163:2041-50. 2003..Panic attacks are known to be more common in women than in men, but the prevalence and correlates of panic in the postmenopausal period have not been well defined... - Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: Women's Health Initiative Memory StudySally A Shumaker
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
JAMA 291:2947-58. 2004..The Women's Health Initiative Memory Study (WHIMS) previously found increased risk for dementia and no effect on mild cognitive impairment (MCI) in women treated with conjugated equine estrogens (CEE) plus medroxyprogesterone acetate (MPA)... - Conjugated equine estrogens and coronary heart disease: the Women's Health InitiativeJudith Hsia
Department of Medicine, George Washington University, Washington, DC, USA
Arch Intern Med 166:357-65. 2006..These trials did not address the role of unopposed estrogen for coronary protection... - Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized TrialRowan T Chlebowski
Harbor UCLA Research and Education Institute, Torrance 90502, USA
JAMA 289:3243-53. 2003..Outstanding issues not previously addressed include characteristics of breast cancers observed among women using hormones and whether diagnosis may be influenced by hormone effects on mammography... - Conjugated equine estrogens and breast cancer risk in the Women's Health Initiative clinical trial and observational studyRoss L Prentice
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Am J Epidemiol 167:1407-15. 2008.... - Estrogen plus progestin therapy and breast cancer in recently postmenopausal womenRoss L Prentice
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Am J Epidemiol 167:1207-16. 2008..64 (95% confidence interval: 1.00, 2.68) over a 5-year period of use and 2.19 (95% confidence interval: 1.56, 3.08) over a 10-year period of use... - Baseline associations between postmenopausal hormone therapy and inflammatory, haemostatic, and lipid biomarkers of coronary heart disease. The Women's Health Initiative Observational StudyRobert D Langer
Department of Family and Preventive Medicine, University of California, San Diego, 9500 Gilman Drive, MC 0978, La Jolla, CA 92093 0978, USA
Thromb Haemost 93:1108-16. 2005..Some associations differed between women with and without incident CHD, especially for EP, where inflammatory and thrombotic markers were higher in cases. These associations remain speculative pending confirmation in randomized trials... - Alcohol and folate consumption and risk of benign proliferative epithelial disorders of the breastYan Cui
Office of Health Assessment and Epidemiology, Los Angeles County Department of Public Health, Los Angeles, CA, USA
Int J Cancer 121:1346-51. 2007..In conclusion, we observed that alcohol consumption and folate intake were not associated with altered risk of BPED, and that there was no effect modification between them in relation to the risk of BPED... - Prior oral contraception and postmenopausal fracture: a Women's Health Initiative observational cohort studyDavid Barad
Obstetrics and Gynecology and Women s Health, Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, New York 10021, USA
Fertil Steril 84:374-83. 2005..To test for the possible association of past oral contraceptive (OC) use and incident fracture after menopause... 
Lipoprotein-associated phospholipase A2, hormone use, and the risk of ischemic stroke in postmenopausal womenSylvia Wassertheil-Smoller
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Hypertension 51:1115-22. 2008....- Panic attacks, daily life ischemia, and chest pain in postmenopausal womenJordan W Smoller
Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA
Psychosom Med 68:824-32. 2006..Chest pain is a common symptom of panic attacks, but little is known about the relationship in older women among panic attacks, chest pain, and daily life ischemia... - Frequency and predictive value of a mammographic recommendation for short-interval follow-upShagufta Yasmeen
University of California, Department of Obstetrics Gynecology and Internal Medicine, Davis, USA
J Natl Cancer Inst 95:429-36. 2003.... - The Women's Health Initiative Observational Study: baseline characteristics of participants and reliability of baseline measuresRobert D Langer
Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92037, USA
Ann Epidemiol 13:S107-21. 2003 - Condom use and the risk of recurrent pelvic inflammatory disease, chronic pelvic pain, or infertility following an episode of pelvic inflammatory diseaseRoberta B Ness
University of Pittsburgh, Graduate School of Public Health, 130 DeSoto St, A530 Crabtree Hall, Pittsburgh, PA 15261, USA
Am J Public Health 94:1327-9. 2004..Consistent condom use (about 60% of encounters) at baseline also reduced these risks, after adjustment for confounders, by 30% to 60%. Self-reported persistent and consistent condom use was associated with lower rates of PID sequelae... - Radiographic measurements, bone mineral density, and the Singh Index in the proximal femur of white and black postmenopausal womenDavid A Barondess
Dis Mon 48:637-46. 2002..Although there were ethnic differences in BMD, there were no ethnic differences in the distribution of the Singh Index scores... - Predictors of chronic pelvic pain in an urban population of women with symptoms and signs of pelvic inflammatory diseaseCatherine L Haggerty
University of Pittsburgh, Department of Epidemiology, Pittsburgh, Pennsylvania 15261, USA
Sex Transm Dis 32:293-9. 2005..69; 95% CI, 0.44-1.10). CONCLUSIONS: A range of demographic, clinical, historical, and behavioral factors predict CPP after PID... - Reanalysis of the Women's Health Initiative oral contraceptive data reveals no evidence of delayed cardiovascular benefitMarcia L Stefanick
Stanford Prevention Research Center, Departments of Medicine and of Obstetrics and Gynecology, Hoover Pavilion, Stanford University, 211 Quarry Road, Stanford, CA 94305 5705, USA
Fertil Steril 83:853-4. 2005..The WHI database was not designed to answer this question... - Menopausal hormone therapy informed consentSusan L Hendrix
Am J Obstet Gynecol 189:S31-2; discussion S32-6. 2003 - Duloxetine compared with placebo for the treatment of women with mixed urinary incontinenceAlfred E Bent
Greater Baltimore Medical Center, Baltimore, Maryland, USA
Neurourol Urodyn 27:212-21. 2008..Evaluate duloxetine in the treatment of women with mixed urinary incontinence (MUI)...