Wei Du

Summary

Affiliation: Wayne State University
Country: USA

Publications

  1. doi request reprint Incidence and costs of adverse drug reactions in a tertiary care pediatric intensive care unit
    Wei Du
    Department of Pediatrics, School of Medicine, Wayne State University, Detroit, MI, USA
    J Clin Pharmacol 53:567-73. 2013
  2. doi request reprint An algorithm to detect adverse drug reactions in the neonatal intensive care unit
    Wei Du
    Department of Pediatrics, School of Medicine, Wayne State University, Detroit, MI, USA
    J Clin Pharmacol 53:87-95. 2013
  3. ncbi request reprint Predictors of enrollment in lung cancer clinical trials
    Wei Du
    Department of Pediatrics, Wayne State University, Detroit, Michigan 48201, USA
    Cancer 106:420-5. 2006
  4. pmc An educational video to increase clinical trials enrollment among breast cancer patients
    Wei Du
    Carman and Ann Adams Department of Pediatrics, Wayne State University, Detroit, MI, USA
    Breast Cancer Res Treat 117:339-47. 2009
  5. doi request reprint An educational video to increase clinical trials enrollment among lung cancer patients
    Wei Du
    Carman and Ann Adams Department of Pediatrics, Wayne State University, Children s Hospital of Michigan, 3901 Beaubien, Room 3N47, Detroit, MI 48201, USA
    J Thorac Oncol 3:23-9. 2008
  6. ncbi request reprint Racial disparities in treatment and survival of women with stage I-III breast cancer at a large academic medical center in metropolitan Detroit
    Wei Du
    Clinical Pharmacology and Toxicology, Carman and Ann Adams Department of Pediatrics, Children s Hospital of Michigan, Wayne State University, Detroit, MI 48201, USA
    Breast Cancer Res Treat 91:243-8. 2005
  7. ncbi request reprint Intermediate follow-up following intravascular stenting for treatment of coarctation of the aorta
    Thomas J Forbes
    Children s Hospital of Michigan, Wayne State University, Detroit, Michigan, USA
    Catheter Cardiovasc Interv 70:569-77. 2007
  8. doi request reprint Vitamin D deficiency is associated with increased left ventricular mass and diastolic dysfunction in children with chronic kidney disease
    Amit R Patange
    Carmen and Ann Adams Department of Pediatrics, Children s Hospital of Michigan, Wayne State University, Detroit, MI, USA
    Pediatr Cardiol 34:536-42. 2013
  9. doi request reprint Perioperative renal failure in pediatric heart transplant recipients: outcome and risk factors
    Liwen Tang
    Division of Cardiology, Children s Hospital of Michigan, Wayne State University, Detroit, MI, USA
    Pediatr Transplant 15:430-6. 2011
  10. doi request reprint Predictors of cardiac allograft vasculopathy in pediatric heart transplant recipients
    Daisuke Kobayashi
    Section of Pediatric Cardiology, Carman and Ann Adams Department of Pediatrics, Children s Hospital of Michigan, Wayne State University School of Medicine, Detroit, MI 48201 2119, USA
    Pediatr Transplant 17:436-40. 2013

Research Grants

Detail Information

Publications42

  1. doi request reprint Incidence and costs of adverse drug reactions in a tertiary care pediatric intensive care unit
    Wei Du
    Department of Pediatrics, School of Medicine, Wayne State University, Detroit, MI, USA
    J Clin Pharmacol 53:567-73. 2013
    ..ADRs increased total ICU costs by 3.5-fold and length of ICU stay by 3.8-fold. Increased ADR surveillance of high risk patients in conjunction with early intervention may reduce drug related morbidity and costs in the PICU...
  2. doi request reprint An algorithm to detect adverse drug reactions in the neonatal intensive care unit
    Wei Du
    Department of Pediatrics, School of Medicine, Wayne State University, Detroit, MI, USA
    J Clin Pharmacol 53:87-95. 2013
    ..Because of the relatively small and nonrandom samples, further refinement and additional testing are needed...
  3. ncbi request reprint Predictors of enrollment in lung cancer clinical trials
    Wei Du
    Department of Pediatrics, Wayne State University, Detroit, Michigan 48201, USA
    Cancer 106:420-5. 2006
    ..Only approximately 5% of patients with newly diagnosed cancer participate in clinical trials nationwide, and African-American (AA) patients are particularly under-represented...
  4. pmc An educational video to increase clinical trials enrollment among breast cancer patients
    Wei Du
    Carman and Ann Adams Department of Pediatrics, Wayne State University, Detroit, MI, USA
    Breast Cancer Res Treat 117:339-47. 2009
    ..Future studies should focus on designing a new educational video to specifically target cultural and attitudinal barriers in the AA population to more effectively change attitudes and increase trial enrollment...
  5. doi request reprint An educational video to increase clinical trials enrollment among lung cancer patients
    Wei Du
    Carman and Ann Adams Department of Pediatrics, Wayne State University, Children s Hospital of Michigan, 3901 Beaubien, Room 3N47, Detroit, MI 48201, USA
    J Thorac Oncol 3:23-9. 2008
    ..A randomized trial was conducted to test the effect of an educational video on positively changing patients' knowledge and attitudes regarding clinical trials and thereby increasing enrollment rates...
  6. ncbi request reprint Racial disparities in treatment and survival of women with stage I-III breast cancer at a large academic medical center in metropolitan Detroit
    Wei Du
    Clinical Pharmacology and Toxicology, Carman and Ann Adams Department of Pediatrics, Children s Hospital of Michigan, Wayne State University, Detroit, MI 48201, USA
    Breast Cancer Res Treat 91:243-8. 2005
    ..Our findings support the theory that equal treatments produce equal outcomes. Improvement in screening may have an important impact on survival among minority women with breast cancer...
  7. ncbi request reprint Intermediate follow-up following intravascular stenting for treatment of coarctation of the aorta
    Thomas J Forbes
    Children s Hospital of Michigan, Wayne State University, Detroit, Michigan, USA
    Catheter Cardiovasc Interv 70:569-77. 2007
    ..We report a multiinstitutional study on intermediate-term outcome of intravascular stenting for treatment of coarctation of the aorta using integrated arch imaging (IAI) techniques...
  8. doi request reprint Vitamin D deficiency is associated with increased left ventricular mass and diastolic dysfunction in children with chronic kidney disease
    Amit R Patange
    Carmen and Ann Adams Department of Pediatrics, Children s Hospital of Michigan, Wayne State University, Detroit, MI, USA
    Pediatr Cardiol 34:536-42. 2013
    ..The cardiovascular changes observed are not easily reversible. Hence, early preventive therapy with vitamin D supplementation is advocated...
  9. doi request reprint Perioperative renal failure in pediatric heart transplant recipients: outcome and risk factors
    Liwen Tang
    Division of Cardiology, Children s Hospital of Michigan, Wayne State University, Detroit, MI, USA
    Pediatr Transplant 15:430-6. 2011
    ..PRF that requires POST (whether or not it began pretransplant) has a significant negative impact on pediatric heart transplant outcome. Specific characteristics identify patients at particular high risk of developing PRF...
  10. doi request reprint Predictors of cardiac allograft vasculopathy in pediatric heart transplant recipients
    Daisuke Kobayashi
    Section of Pediatric Cardiology, Carman and Ann Adams Department of Pediatrics, Children s Hospital of Michigan, Wayne State University School of Medicine, Detroit, MI 48201 2119, USA
    Pediatr Transplant 17:436-40. 2013
    ..14), recipient black race (1.55), and donor cigarette use (1.54). Older recipient and donor age, recipient black race, donor cigarette use, and re-transplantation were highly associated with shorter CAV-free survival. ..
  11. ncbi request reprint Cost-effectiveness and lung cancer clinical trials
    Wei Du
    Center for Cancer Economics, Technology Assessment, Innovation and Development CETAID, Karmanos Cancer Institute, Detroit, Michigan 48201, USA
    Cancer 98:1491-6. 2003
    ..S., with an estimated annual economic burden of $5 billion. Clinical trials offer innovative therapeutic options with potentially better outcomes, but their effects on health care costs are disputed...
  12. doi request reprint Left ventricular systolic dyssynchrony in pediatric and adolescent patients with congestive heart failure
    Srinath T Gowda
    Pediatric Cardiology, Children s Hospital of Michigan, Detroit Medical Center, Wayne State University, Detroit, Michigan 48201 2119, USA
    J Am Soc Echocardiogr 25:486-93. 2012
    ..The aim of this study was to evaluate LV systolic dyssynchrony in pediatric patients with HF and normal children...
  13. ncbi request reprint Factors associated with breast cancer clinical trials participation and enrollment at a large academic medical center
    Michael S Simon
    Hudson Webber Cancer Research Building, 4th Floor, 4100 John R St, Detroit, MI 48201, USA
    J Clin Oncol 22:2046-52. 2004
    ..The practice patterns of medical oncologists at a large National Cancer Institute Comprehensive Cancer Center in Detroit, MI were evaluated to better understand factors associated with accrual to breast cancer clinical trials...
  14. ncbi request reprint Microsatellite alterations in african americans with head and neck cancer
    George H Yoo
    Department of Otolaryngology Head and Neck Surgery, Wayne State University, Detroit, MI, USA
    Laryngoscope 114:1619-24. 2004
    ..To determine the genetic differences between African Americans (AA) and Non-African Americans (NAA) with head and neck squamous cell carcinoma (HNSCC)...
  15. ncbi request reprint Prognostic significance of G1 cell-cycle inhibitors in early laryngeal cancer
    Hakan Korkmaz
    Department of Otolaryngology Head and Neck Surgery, Wayne State University, Detroit, MI 48201, USA
    Am J Otolaryngol 26:77-82. 2005
    ..However, a subset of early laryngeal cancers has a significantly higher rate of local recurrence and lower rate of overall survival...
  16. doi request reprint Predictors of left ventricular remodeling after aortic valve replacement in pediatric patients with isolated aortic regurgitation
    Sujatha Buddhe
    Section of Pediatric Cardiology and Cardiovascular Surgery, Carmen and Ann Adams Department of Pediatrics, The Children s Hospital of Michigan, Wayne State University School of Medicine, Detroit, Mich, USA
    Congenit Heart Dis 8:167-73. 2013
    ..To identify the risk factors that could predict postoperative outcome after aortic valve replacement in pediatric patients with isolated aortic regurgitation (AR)...
  17. doi request reprint Echocardiographic evaluation of pressure gradient across the stent in patients treated for coarctation of the aorta
    Liwen Tang
    Cardiology Division, Department of Pediatrics, Wayne State University School of Medicine, Detroit, Mich 48201, USA
    Congenit Heart Dis 4:269-72. 2009
    ..Stent placement has become a widely used method of treatment for coarctation of the aorta (COA). Our goal was to find echocardiographic indices that would correlate best with directly measured gradients across the coarctation stent...
  18. ncbi request reprint Patterns of drug utilization in a neonatal intensive care unit
    Indulekha Warrier
    Division of Pediatric Clinical Pharmacology, 3N47, Children s Hospital of Michigan, Wayne State University, 3901 Beaubien, Detroit, MI 48201, USA
    J Clin Pharmacol 46:449-55. 2006
    ..Caucasians, males, gestational age<28 weeks, and birthweight<1000 g were the risk factors for higher drug exposure. Future research/education must emphasize these therapeutic areas with priority assigned to low-birthweight infants...
  19. ncbi request reprint Changing patterns of drug utilization in a neonatal intensive care population
    Wei Du
    Division of Clinical Pharmacology and Toxicology, Carmen and Ann Adams Department of Pediatrics, Wayne State University, Detroit, Children s Hospital of Michigan 48201, USA
    Am J Perinatol 23:279-85. 2006
    ..These data are useful in monitoring drug resistance patterns, adverse drug reactions, and prioritizing areas of relevant therapeutic research and educational programs...
  20. doi request reprint Comparison of surgical, stent, and balloon angioplasty treatment of native coarctation of the aorta: an observational study by the CCISC (Congenital Cardiovascular Interventional Study Consortium)
    Thomas J Forbes
    Children s Hospital of Michigan, Detroit, USA
    J Am Coll Cardiol 58:2664-74. 2011
    ..The purpose of this study was to compare the safety and efficacy of surgical, stent, and balloon angioplasty (BA) treatment of native coarctation acutely and at follow-up...
  21. doi request reprint Low donor-to-recipient weight ratio does not negatively impact survival of pediatric heart transplant patients
    Liwen Tang
    Division of Pediatric Cardiology, Children s Hospital of Michigan, Detroit, MI 48201, USA
    Pediatr Transplant 14:741-5. 2010
    ..6-0.79 and DRWR 0.8-2.0. Use of smaller allografts (DRWR 0.6-0.8) has no negative impact on the short- and long-term survival of pediatric heart transplant patients...
  22. doi request reprint Radiofrequency and cryoablation therapies for supraventricular arrhythmias in the young: five-year review of efficacies
    Sujatha Buddhe
    Section of Pediatric Cardiology, Carmen and Ann Adams Department of Pediatrics, The Children s Hospital of Michigan, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    Pacing Clin Electrophysiol 35:711-7. 2012
    ..Although initial acute results and more recent, but limited, 3-36-month follow-up studies have been reported, more longer follow-up information is required to determine actual efficacy...
  23. doi request reprint Left ventricular mechanical synchrony and global systolic function in pediatric patients late after ventricular septal defect patch closure: a three-dimensional echocardiographic study
    Surendranath Reddy Veeram Reddy
    Children s Hospital of Michigan, Division of Cardiology, The Carmen and Ann Adams Department of Pediatrics, Detroit, MI 48201, USA
    Congenit Heart Dis 4:454-8. 2009
    ..The long-term effects of the presence of akinetic patch in the ventricular septum and postoperative right bundle branch block (RBBB) on the left ventricular (LV) mechanical synchrony and global systolic function have not been studied...
  24. ncbi request reprint Improving surgical outcomes: standardizing the reporting of incidence and severity of acute lymphedema after sentinel lymph node biopsy and axillary lymph node dissection
    Wesley P Francis
    Surgical Section, John D Dingell, Veterans Affairs Medical Center, Detroit, MI, USA
    Am J Surg 192:636-9. 2006
  25. doi request reprint Risk factors for atrioventricular tachycardia degenerating to atrial flutter/fibrillation in the young with Wolff-Parkinson-White
    Ashraf Harahsheh
    Section of Pediatric Cardiology, Carmen and Ann Adams Department of Pediatrics, Children s Hospital of Michigan, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    Pacing Clin Electrophysiol 31:1307-12. 2008
    ..Although AF occurs in 18% of adult WPW pts, its incidence in children is unknown. We sought to determine risk factors for AVRT spontaneously degenerating to AF during electrophysiologic studies (EPS) in children with WPW...
  26. doi request reprint Vitamin D deficiency and arterial wall stiffness in children with chronic kidney disease
    Amit R Patange
    Carmen and Ann Adams Department of Pediatrics, Children s Hospital of Michigan, Wayne State University, Detroit, MI, USA
    Pediatr Cardiol 33:122-8. 2012
    ..The pathophysiologic mechanisms of vitamin D that regulate increased arterial stiffness need to be integrated further in pediatric CKD patients...
  27. doi request reprint Impact of pulmonary hypertension on transplant outcomes in pediatric cardiomyopathy patients
    Sujatha Buddhe
    Section of Pediatric Cardiology, Carmen and Ann Adams Department of Pediatrics, The Children s Hospital of Michigan, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Pediatr Transplant 16:367-72. 2012
    ..Pre-transplant PHTN increases early post-transplant mortality in pediatric cardiomyopathy patients above one yr of age. There has been no significant improvement in the outcome of this group over the last seven yr...
  28. ncbi request reprint Phase II trial of estramustine and etoposide in androgen-sensitive metastatic prostate carcinoma
    Ulka Vaishampayan
    Division of Hematology Oncology, Barbara Ann Karmanos Cancer Institute and Wayne State University, Detroit, Michiga, USA
    Am J Clin Oncol 27:550-4. 2004
    ..Hence, a phase II trial was conducted to evaluate the efficacy and toxicity of estramustine and etoposide in hormone-sensitive metastatic prostate cancer...
  29. ncbi request reprint Biofilm density in the pediatric nasopharynx: recurrent acute otitis media versus obstructive sleep apnea
    Giancarlo Zuliani
    Division of Pediatric Otolaryngology, Department of Otolaryngology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    Ann Otol Rhinol Laryngol 118:519-24. 2009
    ..We compared the biofilm surface density of adenoids removed from children with recurrent acute otitis media (RAOM) to that of adenoids removed from children with a diagnosis of obstructive sleep apnea (OSA)...
  30. ncbi request reprint Procedural results and acute complications in stenting native and recurrent coarctation of the aorta in patients over 4 years of age: a multi-institutional study
    Thomas J Forbes
    Division of Cardiology, Children s Hospital of Michigan, and Wayne State University, Detroit, Michigan 48201, USA
    Catheter Cardiovasc Interv 70:276-85. 2007
    ..We report a multi-institutional experience with intravascular stenting (IS) for treatment of coarctation of the aorta...
  31. ncbi request reprint Can a practicing surgeon detect early lymphedema reliably?
    Keiva L Bland
    Department of Surgery, School of Medicine, Wayne State University, Detroit, MI, USA
    Am J Surg 186:509-13. 2003
    ..Lymphedema may be identified by simpler circumference changes as compared with changes in limb volume...
  32. ncbi request reprint Screening for domestic violence in a general pediatric clinic: be prepared!
    Teresa G Holtrop
    Carman and Ann Adams Department of Pediatrics, Wayne State University, Detroit, Michigan, USA
    Pediatrics 114:1253-7. 2004
    ..We set out to determine whether the use of the Partner Violence Screen (PVS) increases detection of DV and to test the mechanics of implementing large-scale DV screening in a busy, pediatric residency training clinic...
  33. ncbi request reprint Evaluation of left ventricular diastolic function in pediatric sickle cell disease patients
    Mark V Zilberman
    Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan, USA
    Am J Hematol 82:433-8. 2007
    ..There are strong positive relations between left ventricular hypertrophy and right ventricular pressure in these patients. TDI should be employed in the evaluation of SCD patients...
  34. doi request reprint Nephropathy in patients after Fontan palliation
    Premchand Anne
    Division of Cardiology, Wayne State University, Detroit, MI 48202, USA
    Int J Cardiol 132:244-7. 2009
    ..As the effect of Fontan circulation on the kidneys has not been defined, the purpose of this study was to determine whether it is associated with nephropathy...
  35. doi request reprint Regression equations for calculation of z scores of cardiac structures in a large cohort of healthy infants, children, and adolescents: an echocardiographic study
    Michael D Pettersen
    Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan, USA
    J Am Soc Echocardiogr 21:922-34. 2008
    ..Accordingly, we sought to develop normative data in a large pediatric cohort using modern echocardiographic equipment from which z scores could be calculated...
  36. ncbi request reprint Neoadjuvant docetaxel and estramustine chemotherapy in high-risk/locallyadvanced prostate cancer
    Maha Hussain
    Division of Hematology Oncology, Wayne State University and Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, USA
    Urology 61:774-80. 2003
    ..To evaluate the efficacy and safety of neoadjuvant docetaxel and estramustine in patients with high-risk, newly diagnosed, prostate cancer...
  37. ncbi request reprint Prognostic significance of p53 and FHIT in advanced oropharyngeal carcinoma
    Jose E Otero-Garcia
    Department of Otolaryngology, Wayne State University, Detroit, MI 48201, USA
    Am J Otolaryngol 25:231-9. 2004
    ..To determine the prognostic significance of p53 and fragile histidine triad (FHIT) expression in advanced oropharyngeal squamous cell carcinoma...
  38. ncbi request reprint Predictors of nodal metastasis in salivary gland cancer
    Hakan Korkmaz
    Department of Otolaryngology Head and Neck Surgery, Karmanos Cancer Institute Wayne State University, Detroit, Michigan 48201, USA
    J Surg Oncol 80:186-9. 2002
    ..This study was conducted to determine clinical and histologic factors that would predict nodal metastasis in patients with major salivary gland cancer...
  39. pmc Detecting novel low-abundant transcripts in Drosophila
    Sanggyu Lee
    Department of Medicine, University of Chicago, IL 60637, USA
    RNA 11:939-46. 2005
    ..Our study reveals the presence of a significant number of novel low-abundant transcripts in Drosophila, and highlights the need to isolate these novel low-abundant transcripts for further biological studies...
  40. doi request reprint Comparison of methods to correct the miscounting of multiple episodes of care when estimating the incidence of hospitalised injury in child motor vehicle passengers
    Wei Du
    NSW Injury Risk Management Research Centre, University of New South Wales, 2052 NSW, Australia
    Accid Anal Prev 40:1563-8. 2008
    ..However, the correction criterion which is optimal may vary depending on different study objectives and different types of hospitalised injuries...
  41. ncbi request reprint Alvimopan accelerates gastrointestinal recovery after bowel resection regardless of age, gender, race, or concomitant medication use
    Anthony J Senagore
    Spectrum Health System, Research and Medical Education, Grand Rapids, Michigan 49503, USA
    Surgery 142:478-86. 2007
    ..Alvimopan, a peripherally acting mu-opioid receptor antagonist accelerated gastrointestinal (GI) recovery in 5 randomized, double-blind, phase III postoperative ileus trials...
  42. ncbi request reprint Phase III trial of alvimopan, a novel, peripherally acting, mu opioid antagonist, for postoperative ileus after major abdominal surgery
    Conor P Delaney
    Department of Colorectal Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Dis Colon Rectum 48:1114-25; discussion 1125-6; author reply 1127-9. 2005
    ..There is no approved treatment for postoperative ileus. Alvimopan is a novel, peripherally acting, mu opioid receptor antagonist currently in development for the management of postoperative ileus...

Research Grants1

  1. A Videotape to Increase Cancer Clinical Trials Particip*
    Wei Du; Fiscal Year: 2004
    ..Our hypothesis is that the educational videotape will increase patients' knowledge and promote positive attitudes toward cancer clinical trials and thereby increase trial participation. ..