Research Topics
| Vaibhav A DiwadkarSummaryAffiliation: Wayne State University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Adolescent risk pathways toward schizophrenia: sustained attention and the brainV A Diwadkar
Division of Brain Research and Imaging Neuroscience, Dept of Psychiatry and Behavioral Neuroscience, Wayne State University SOM, UHC 9B, 4201 St Antoine Blvd, Detroit, MI 48201, USA
Curr Top Med Chem 12:2339-47. 2012..We end by advocating the application of systems-based approaches toward understanding the progression of network dysfunction in the adolescent risk-state...
The neural correlates of performance in adolescents at risk for schizophrenia: inefficiently increased cortico-striatal responses measured with fMRIVaibhav A Diwadkar
Department of Psychiatry and Behavioral Neuroscience, Wayne State University SOM, MI 48201, USA
J Psychiatr Res 46:12-21. 2012....
Disordered corticolimbic interactions during affective processing in children and adolescents at risk for schizophrenia revealed by functional magnetic resonance imaging and dynamic causal modelingVaibhav A Diwadkar
Division of Brain Research and Imaging Neuroscience, Department of Psychiatry and Behavioral Neuroscience, Wayne State University School of Medicine, Detroit, MI 48201, USA
Arch Gen Psychiatry 69:231-42. 2012..Disordered functional architecture of brain networks may contribute to the well-documented increased risk for psychiatric disorders in offspring of patients with schizophrenia...
Fronto-parietal hypo-activation during working memory independent of structural abnormalities: conjoint fMRI and sMRI analyses in adolescent offspring of schizophrenia patientsVaibhav A Diwadkar
Psychiatry and Behavioral Neuroscience, Wayne State University SOM, USA
Neuroimage 58:234-41. 2011..Further studies will be needed to more closely assess whether impairments in function and structure provide independent or interacting pathways of vulnerability in this population...
Working memory and attention deficits in adolescent offspring of schizophrenia or bipolar patients: comparing vulnerability markersVaibhav A Diwadkar
Dept of Psychiatry and Behavioral Neuroscience, Wayne State University SOM, Detroit, MI 48301, USA
Prog Neuropsychopharmacol Biol Psychiatry 35:1349-54. 2011..Here we assess impairments in offspring of schizophrenia (SCZ-Offspring) or bipolar (BP-Offspring) patients compared to controls (HC) with no family history of mood or psychotic disorders to the second degree...
Hypo-activation in the executive core of the sustained attention network in adolescent offspring of schizophrenia patients mediated by premorbid functional deficitsVaibhav A Diwadkar
Department of Psychiatry and Behavioral Neuroscience, Wayne State University, Detroit, MI 48201, USA
Psychiatry Res 192:91-9. 2011..Assessing the relationship between clinical measures and brain activity in domains such as attention provides a window into mechanisms of vulnerability in the developing adolescent brain...
Inefficiently increased anterior cingulate modulation of cortical systems during working memory in young offspring of schizophrenia patientsNeil Bakshi
Dept of Psychiatry and Behavioral Neuroscience, Wayne State University SOM, MI 48201, USA
J Psychiatr Res 45:1067-76. 2011....
Reduced intra-amygdala activity to positively valenced faces in adolescent schizophrenia offspringTracy Barbour
Psychiatry and Behavioral Neuroscience, Wayne State University SOM, Detroit, MI 48301, United States
Schizophr Res 123:126-36. 2010....
Genetically predisposed offspring with schizotypal features: an ultra high-risk group for schizophrenia?Vaibhav A Diwadkar
Depatment of Psychiatry and Behavioral Neuroscience, Wayne State University School of Medicine, Detroit, MI 48201, USA
Prog Neuropsychopharmacol Biol Psychiatry 30:230-8. 2006..We propose that schizotypy may define a hyper vulnerable sub-sample among individuals genetically predisposed to schizophrenia and that future studies that attempt to assess risk may benefit from such a convergent approach...
fMRI responses to emotional faces in children and adolescents at genetic risk for psychiatric illness share some of the features of depressionTracy Barbour
Department of Psychiatry and Behavioral Neuroscience, Wayne State University School of Medicine, Detroit, MI 48201, United States
J Affect Disord 136:276-85. 2012..The relevance of cortico-limbic models of emotion and reward processing in children with genetic risk for psychiatric disorders has not been assessed...
Do premorbid impairments predict emergent 'prodromal' symptoms in young relatives at risk for schizophrenia?Matcheri S Keshavan
Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, Michigan, USA
Early Interv Psychiatry 3:213-20. 2009..A better understanding of the role of these abnormalities in predicting later onset of 'prodromal' symptoms or psychosis may help in early identification of SZ...
Congruence of happy and sad emotion in music and faces modifies cortical audiovisual activationJeong Won Jeong
Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI 48201, USA
Neuroimage 54:2973-82. 2011..We hypothesized that neural mechanisms involved in listening to music may differ when presented together with visual stimuli that conveyed the same emotion as the music when compared to visual stimuli with incongruent emotional content...
Pituitary volume in neuroleptic-naïve schizophrenia: a structural MRI studyAmeet R Upadhyaya
Brain Research and Imaging Neuroscience, Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, MI 48201, USA
Schizophr Res 90:266-73. 2007..Similar volume reductions have been seen in other neuropsychiatric populations and may cut across diagnostic boundaries...
Premorbid indicators and risk for schizophrenia: a selective review and updateMatcheri S Keshavan
Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, 4201 St Antoine, Suite 9B, Detroit, MI 48201, USA
Schizophr Res 79:45-57. 2005..Collectively, such data may help us to predict the eventual emergence of schizophrenia, and schizophrenia spectrum or non-spectrum psychopathology...
Evaluating reverse speech as a control task with language-related gamma activity on electrocorticographyErik C Brown
MD PhD Program, School of Medicine, Wayne State University, Detroit, MI 48201, USA
Neuroimage 60:2335-45. 2012..Superior temporal lobe engagement may indicate increased attention to reverse speech. Reverse speech does not appear to be a suitable task for the control of non-language auditory functions on ECoG...
Impaired associative learning in schizophrenia: behavioral and computational studiesVaibhav A Diwadkar
Department of Psychiatry and Behavioral Neuroscience, Wayne State University SOM, Detroit, MI, USA
Cogn Neurodyn 2:207-19. 2008..The synergy between experimental research and a detailed computational model of performance provides a framework within which to infer plausible biological bases of impaired learning dynamics in schizophrenia...
