Yuchuan Ding

Summary

Affiliation: Wayne State University
Country: USA

Publications

  1. ncbi request reprint Impaired motor learning and diffuse axonal damage in motor and visual systems of the rat following traumatic brain injury
    Y Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, Room 48550, W Canfield, Detroit, MI 48201, USA
    Neurol Res 23:193-202. 2001
  2. ncbi request reprint Local saline infusion into ischemic territory induces regional brain cooling and neuroprotection in rats with transient middle cerebral artery occlusion
    Yuchuan Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, Room 48, 550 East Canfield, Detroit, MI 48201, USA
    Neurosurgery 54:956-64; discussion 964-5. 2004
  3. ncbi request reprint Motor balance and coordination training enhances functional outcome in rat with transient middle cerebral artery occlusion
    Y Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, 550 East Canfield, 48201, Detroit, MI, USA
    Neuroscience 123:667-74. 2004
  4. ncbi request reprint Reduced inflammatory mediator expression by pre-reperfusion infusion into ischemic territory in rats: a real-time polymerase chain reaction analysis
    Yuchuan Ding
    Department of Neurological Surgery, Lande Medical Research Building, Room 48, 550 East Canfield, Detroit, MI 48201, USA
    Neurosci Lett 353:173-6. 2003
  5. ncbi request reprint Synaptic plasticity in thalamic nuclei enhanced by motor skill training in rat with transient middle cerebral artery occlusion
    Yuchuan Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, Room 48, 550 E Canfield, Detroit, MI 48201, USA
    Neurol Res 25:189-94. 2003
  6. ncbi request reprint Functional improvement after motor training is correlated with synaptic plasticity in rat thalamus
    Yuchuan Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, Room 48, 550 E Canfield, Detroit, MI 48201, USA
    Neurol Res 24:829-36. 2002
  7. ncbi request reprint Prereperfusion saline infusion into ischemic territory reduces inflammatory injury after transient middle cerebral artery occlusion in rats
    Yuchuan Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, Mich 48201, USA
    Stroke 33:2492-8. 2002
  8. ncbi request reprint Exercise pre-conditioning reduces brain damage in ischemic rats that may be associated with regional angiogenesis and cellular overexpression of neurotrophin
    Y Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, Room 48, 550 East Canfield Street, Detroit, MI 48201, USA
    Neuroscience 124:583-91. 2004
  9. ncbi request reprint Impaired motor activity and motor learning function in rat with middle cerebral artery occlusion
    Yuchuan Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, Room 48, 550 E Canfield, Detroit, MI 48201, USA
    Behav Brain Res 132:29-36. 2002
  10. ncbi request reprint Prereperfusion flushing of ischemic territory: a therapeutic study in which histological and behavioral assessments were used to measure ischemia-reperfusion injury in rats with stroke
    Yuchuan Ding
    Department of Neurological Surgery and Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    J Neurosurg 96:310-9. 2002

Collaborators

Detail Information

Publications59

  1. ncbi request reprint Impaired motor learning and diffuse axonal damage in motor and visual systems of the rat following traumatic brain injury
    Y Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, Room 48550, W Canfield, Detroit, MI 48201, USA
    Neurol Res 23:193-202. 2001
    ..These findings suggest that motor learning deficits could be detected in mild or moderate brain injury, and this deficit could be attributed to a diffuse axonal injury distributed both in the motor and the visual systems...
  2. ncbi request reprint Local saline infusion into ischemic territory induces regional brain cooling and neuroprotection in rats with transient middle cerebral artery occlusion
    Yuchuan Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, Room 48, 550 East Canfield, Detroit, MI 48201, USA
    Neurosurgery 54:956-64; discussion 964-5. 2004
    ..g., pneumonia). The goal of this study was to determine whether local infusion of saline into ischemic territory could induce regional brain cooling and neuroprotection...
  3. ncbi request reprint Motor balance and coordination training enhances functional outcome in rat with transient middle cerebral artery occlusion
    Y Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, 550 East Canfield, 48201, Detroit, MI, USA
    Neuroscience 123:667-74. 2004
    ..The data suggest that complex motor training rather than simple exercise effectively improves functional outcome...
  4. ncbi request reprint Reduced inflammatory mediator expression by pre-reperfusion infusion into ischemic territory in rats: a real-time polymerase chain reaction analysis
    Yuchuan Ding
    Department of Neurological Surgery, Lande Medical Research Building, Room 48, 550 East Canfield, Detroit, MI 48201, USA
    Neurosci Lett 353:173-6. 2003
    ..This increase was significantly reduced at both 6 and 12 h post-reperfusion as a result of saline flushing...
  5. ncbi request reprint Synaptic plasticity in thalamic nuclei enhanced by motor skill training in rat with transient middle cerebral artery occlusion
    Yuchuan Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, Room 48, 550 E Canfield, Detroit, MI 48201, USA
    Neurol Res 25:189-94. 2003
    ..The data suggest that motor training, particularly motor skill training involving balance and coordination, facilitates a uniquely lateralized synaptogenesis in the thalamus...
  6. ncbi request reprint Functional improvement after motor training is correlated with synaptic plasticity in rat thalamus
    Yuchuan Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, Room 48, 550 E Canfield, Detroit, MI 48201, USA
    Neurol Res 24:829-36. 2002
    ..Both Rota-rod and treadmill could be quantitatively used in rats for motor training of different complexity...
  7. ncbi request reprint Prereperfusion saline infusion into ischemic territory reduces inflammatory injury after transient middle cerebral artery occlusion in rats
    Yuchuan Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, Mich 48201, USA
    Stroke 33:2492-8. 2002
    ....
  8. ncbi request reprint Exercise pre-conditioning reduces brain damage in ischemic rats that may be associated with regional angiogenesis and cellular overexpression of neurotrophin
    Y Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, Room 48, 550 East Canfield Street, Detroit, MI 48201, USA
    Neuroscience 124:583-91. 2004
    ..Physical activity reduced stroke damage. The reduced brain damage may be attributable to angiogenesis and neurotrophin overexpression in brain regions supplied by the MCA following exercise...
  9. ncbi request reprint Impaired motor activity and motor learning function in rat with middle cerebral artery occlusion
    Yuchuan Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, Room 48, 550 E Canfield, Detroit, MI 48201, USA
    Behav Brain Res 132:29-36. 2002
    ..Both motor learning and motor function were impaired in ischemic rats. The motor tests used in this study are sensitive, semi-quantitative, and reproducible measurements of functional impairment in rats following an ischemic stroke...
  10. ncbi request reprint Prereperfusion flushing of ischemic territory: a therapeutic study in which histological and behavioral assessments were used to measure ischemia-reperfusion injury in rats with stroke
    Yuchuan Ding
    Department of Neurological Surgery and Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    J Neurosurg 96:310-9. 2002
    ....
  11. ncbi request reprint Neuron tolerance during hydrocephalus
    Y Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Neuroscience 106:659-67. 2001
    ..Less neuron death in hydrocephalic rats after acute forebrain ischemia suggests that neuronal tolerance to ischemia occurs during hydrocephalus...
  12. ncbi request reprint Long-term neuroprotective effect of inhibiting poly(ADP-ribose) polymerase in rats with middle cerebral artery occlusion using a behavioral assessment
    Y Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, Room 48, 550 E Canfield St, Detroit, MI 48201, USA
    Brain Res 915:210-7. 2001
    ..The motor tests employed in this study can be used as sensitive, objective and reproducible measurements of functional impairment in rats following an ischemic stroke...
  13. ncbi request reprint Axonal damage associated with enlargement of ventricles during hydrocephalus: a silver impregnation study
    Y Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Neurol Res 23:581-7. 2001
    ..The major pathological change of brain regions involved in motor and learning functions during hydrocephalus is axon degeneration, and this degeneration is correlated with an enlargement of the cerebral ventricles...
  14. ncbi request reprint Impaired motor learning in children with hydrocephalus
    Y Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, Mich 48201, USA
    Pediatr Neurosurg 34:182-9. 2001
    ..These findings could lead to the formulation of training procedures with simplified movements that may help hydrocephalic children improve their motor skill learning...
  15. ncbi request reprint Exercise preconditioning ameliorates inflammatory injury in ischemic rats during reperfusion
    Yun Hong Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, Room 48, 550 E Canfield Street, Detroit, MI 48201, USA
    Acta Neuropathol 109:237-46. 2005
    ..Chronically increased expression of TNF-alpha during exercise prevent the same downstream inflammatory events as does acutely elevated TNF-alpha after ischemia/reperfusion...
  16. doi request reprint Neuronal damage and functional deficits are ameliorated by inhibition of aquaporin and HIF1α after traumatic brain injury (TBI)
    Mohammed Shenaq
    Department of Neurological Surgery, Wayne State University School of Medicine and College of Engineering, Detroit, MI, USA
    J Neurol Sci 323:134-40. 2012
    ..The data further suggests that upstream modulation of the molecular patho-trajectory effectively ameliorates both neuronal injury and behavioral deficits post-TBI...
  17. ncbi request reprint Exercise pre-conditioning strengthens brain microvascular integrity in a rat stroke model
    Yun Hong Ding
    Department of Neurosurgery, Wayne State University School of Medicine, USA
    Neurol Res 28:184-9. 2006
    ..This exercise-induced endogenous neuroprotection could be an effective strategy to ameliorate ischemic brain injury from stroke...
  18. ncbi request reprint Exercise-induced overexpression of angiogenic factors and reduction of ischemia/reperfusion injury in stroke
    Yun Hong Ding
    Department of Neurologicalal Surgery, Wayne State University School of Medicine, Lande Medical Research Building, Room 48, 550 E Canfield Street, Detroit, MI 48201, USA
    Curr Neurovasc Res 1:411-20. 2004
    ..The reduced damage is associated with angiogenesis, possibly induced by angiogenic factors following exercise. Physical exercise up-regulates mRNA levels of the angiopoietin family and VEGF...
  19. doi request reprint Reduction of brain edema and expression of aquaporins with acute ethanol treatment after traumatic brain injury
    Tony Wang
    Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    J Neurosurg 118:390-6. 2013
    ..To establish the potential neuroprotective properties of ethanol as a post-TBI therapy, in the present study the authors determined the effect of ethanol on brain edema, AQP expression, and functional outcomes in a post-TBI setting...
  20. doi request reprint Glycerol accumulation in edema formation following diffuse traumatic brain injury
    Ahmer Ali
    Wayne State University, School of Medicine, Detroit, MI 48201, USA
    Neurol Res 34:462-8. 2012
    ..The implication of HIF-1alpha and AQP9 underlying TBI-induced edema formation offers possibilities for novel TBI therapies...
  21. ncbi request reprint Increased astrocyte proliferation in rats after running exercise
    Jie Li
    Department of Neurological Surgery, Wayne State University School of Medicine, Canfield, Detroit, MI 48201, USA
    Neurosci Lett 386:160-4. 2005
    ..Strengthening of this unit by exercise may protect blood-brain-barrier function following brain injury, such as that occurring after stroke...
  22. ncbi request reprint Neuroprotection against transient cerebral ischemia by exercise pre-conditioning in rats
    Jie Li
    Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Neurol Res 26:404-8. 2004
    ..This exercise-induced endogenous neuroprotection may be an effective strategy to ameliorate ischemia/reperfusion brain injury from stroke...
  23. ncbi request reprint Regional brain cooling induced by vascular saline infusion into ischemic territory reduces brain inflammation in stroke
    Xiaodong Luan
    Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, Room 48, 550 E Canfield, Detroit, MI 48201, USA
    Acta Neuropathol 107:227-34. 2004
    ..In conclusion, brain hypothermia induced by local pre-reperfusion infusion ameliorated brain inflammation from stroke...
  24. doi request reprint Neuroprotection conferred by post-ischemia ethanol therapy in experimental stroke: an inhibitory effect on hyperglycolysis and NADPH oxidase activation
    Ryan Kochanski
    Department of Neurosurgery, Wayne State University School of Medicine, Detroit, Michigan, USA
    J Neurochem 126:113-21. 2013
    ..Because of the lack of associated hypoglycemia and selectivity toward decreasing cerebral metabolism, further investigation of ethanol's use as a post-stroke therapy, especially in the context of hyperglycemia, seems warranted...
  25. ncbi request reprint Long-term neuroprotection induced by regional brain cooling with saline infusion into ischemic territory in rats: a behavioral analysis
    Jie Li
    Department of Neurological Surgery, Wayne State University School of Medicine, Canfield, Detroit, MI 48201, USA
    Neurol Res 26:677-83. 2004
    ....
  26. doi request reprint Acute administration of ethanol reduces apoptosis following ischemic stroke in rats
    Paul Fu
    Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Neurosci Res 76:93-7. 2013
    ..This results in a significant reduction of neuronal apoptosis and is neuroprotective in ischemia-reperfusion injury...
  27. ncbi request reprint Cerebral angiogenesis and expression of angiogenic factors in aging rats after exercise
    Yun Hong Ding
    Neurological Surgery, Wayne State University School of Medicine, USA
    Curr Neurovasc Res 3:15-23. 2006
    ..The induced angiogenesis was associated with overexpression of angiogenic factors. These results support the hypothesis that an angiogenic response to chronic physical exercise is maintained with aging...
  28. ncbi request reprint Hypoxia-inducible factor-1α contributes to brain edema after stroke by regulating aquaporins and glycerol distribution in brain
    Tetsuhiro Higashida
    Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    Curr Neurovasc Res 8:44-51. 2011
    ..Pharmacological blockade of this pathway in stroke patients may provide novel therapeutic strategies...
  29. doi request reprint Combined effect of tumor necrosis factor (TNF)-alpha and heat shock protein (HSP)-70 in reducing apoptotic injury in hypoxia: a cell culture study
    Gunjan Goel
    Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Neurosci Lett 483:162-6. 2010
    ..This study suggested that TNF-alpha and HSP-70 together enhance the decrease in pro-apoptotic protein levels and the increase in anti-apoptotic protein levels in the event of neuronal hypoxia through ERK1/2 signal transduction...
  30. doi request reprint Preischemic exercise reduces brain damage by ameliorating metabolic disorder in ischemia/reperfusion injury
    David Dornbos
    Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    J Neurosci Res 91:818-27. 2013
    ..Altogether, exercise preconditioning increased the rates of glucose metabolism, allowing a more rapid and more substantial increase in ATP production following stroke...
  31. doi request reprint Matrix metalloproteinase-9 (MMP-9) expression and extracellular signal-regulated kinase 1 and 2 (ERK1/2) activation in exercise-reduced neuronal apoptosis after stroke
    Khawar Chaudhry
    Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, MI 48201, United States
    Neurosci Lett 474:109-14. 2010
    ..This study has suggested that exercise-induced neuroprotection in I/R injury may be mediated by MMP-9 and ERK1/2 expression, leading to a reduction in neuronal apoptosis...
  32. doi request reprint At low doses ethanol maintains blood-brain barrier (BBB) integrity after hypoxia and reoxygenation: a brain slice study
    Changya Peng
    Wayne State University School of Medicine, Detroit, MI, USA
    Neurol Res 35:790-7. 2013
    ..These effects may indicate a beneficial effect of EtOH on BBB integrity after stroke...
  33. doi request reprint Pre-ischemic exercise preserves cerebral blood flow during reperfusion in stroke
    Nathan Zwagerman
    Department of Neurosurgery, Wayne State University School of Medicine, Detroit, MI, USA
    Neurol Res 32:523-9. 2010
    ..This study aims to determine if cerebral blood flow is constituently higher during the ischemia or reperfusion events in stroke...
  34. doi request reprint Cerebral metabolism after forced or voluntary physical exercise
    Harish Kinni
    Department of Neurosurgery, Wayne State University School of Medicine, Detroit, MI, USA
    Brain Res 1388:48-55. 2011
    ....
  35. doi request reprint Toll-like receptor-4 and cytokine cascade in stroke after exercise
    Nathan Zwagerman
    Department of Neurosurgery, Wayne State University School of Medicine, Detroit, MI, USA
    Neurol Res 32:123-6. 2010
    ..This study explores the expression of Toll-like receptor-4 in brain parenchyma during an ischemic stroke after exercise, in association with brain injury...
  36. ncbi request reprint Reduced brain edema and matrix metalloproteinase (MMP) expression by pre-reperfusion infusion into ischemic territory in rat
    Yun Hong Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Lande Medical Research Building, Room 48, 550 E Canfield, Detroit, MI 48201, USA
    Neurosci Lett 372:35-9. 2004
    ..This study has enhanced our understanding of the causal mechanisms by which the neuroprotective effect of ischemic area "flushing" can be achieved...
  37. doi request reprint The role of hypoxia-inducible factor-1α, aquaporin-4, and matrix metalloproteinase-9 in blood-brain barrier disruption and brain edema after traumatic brain injury
    Tetsuhiro Higashida
    Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    J Neurosurg 114:92-101. 2011
    ....
  38. doi request reprint Reduced apoptosis by combining normobaric oxygenation with ethanol in transient ischemic stroke
    Xiaokun Geng
    China America Institute of Neuroscience, Luhe Hospital, Capital Medical University, Beijing, China
    Brain Res 1531:17-24. 2013
    ..The present study evaluated the effect of NBO on ischemia-induced apoptosis and assessed the potential for improved outcomes by combining NBO administration with another neuroprotective agent, ethanol, in a rat stroke model...
  39. ncbi request reprint Neuroprotection & mechanism of ethanol in stroke and traumatic brain injury therapy: new prospects for an ancient drug
    Karam Asmaro
    Department of Neurological Surgery, Wayne State University School of Medicine, 550 E Canfield Rd, Detroit, MI 48201, USA
    Curr Drug Targets 14:74-80. 2013
    ....
  40. ncbi request reprint Mechanisms of neuronal damage and neuroprotection underlying ischemia/reperfusion injury after physical exercise
    David Dornbos
    Department of Neurosurgery, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Curr Drug Targets 13:247-62. 2012
    ....
  41. doi request reprint Ethanol reduces expression of apoptotic proteins after hypoxia/reoxygenation in a brain slice model
    Yu Yuan
    Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Neurol Res 34:373-8. 2012
    ..To assess overall cell viability following ethanol treatment, ADP/ATP ratio was measured...
  42. ncbi request reprint Effects of hydrocephalus and ventriculoperitoneal shunt therapy on afferent and efferent connections in the feline sensorimotor cortex
    Ramin Eskandari
    Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    J Neurosurg 101:196-210. 2004
    ..To examine connectivity-related changes directly, the authors conducted a study in which they used an axonal tracer in an animal model of infantile hydrocephalus...
  43. doi request reprint Pericyte-mediated vasoconstriction underlies TBI-induced hypoperfusion
    Paula Dore-Duffy
    Department of Neurology, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Neurol Res 33:176-86. 2011
    ..In this study we question the role of the microvascular pericyte in endothelin-1-mediated pathophysiology in TBI...
  44. doi request reprint Safety and validity of mechanical thrombectomy and thrombolysis on severe cerebral venous sinus thrombosis
    Guangwen Li
    Xuanwu Hospital, Capital Medical University, Beijing, China
    Neurosurgery 72:730-8; discussion 730. 2013
    ..These patients, especially younger people, as documented by hospital-based studies, have a high morbidity and mortality rate...
  45. doi request reprint Neuroprotective effect of acute ethanol administration in a rat with transient cerebral ischemia
    Fei Wang
    Cerebral Vascular Diseases Institute, Xuanwu Hospital, Capital Medical University, Beijing, China
    Stroke 43:205-10. 2012
    ..Ethanol consumption is inversely associated with the risk of ischemic stroke, suggesting a neuroprotective effect. In a rat model of transient cerebral ischemia, we identified ethanol as a possible treatment for acute ischemic stroke...
  46. doi request reprint Hyperglycemia in stroke and possible treatments
    William A Li
    Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, MI, USA
    Neurol Res 35:479-91. 2013
    ..Elucidation of these mechanistic pathways could lead to the development of rational treatments that reduce hyperglycemia-associated injuries and improve functional outcomes for ischemic stroke patients...
  47. ncbi request reprint Current concepts on the expression of neurotrophins in the greater omentum
    Manuel Dujovny
    Department of Neurosurgery, Wayne State University, Detroit, MI, USA
    Neurol Res 26:226-9. 2004
    ....
  48. ncbi request reprint Exercise preconditioning upregulates cerebral integrins and enhances cerebrovascular integrity in ischemic rats
    Y H Ding
    Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, MI, USA
    Acta Neuropathol 112:74-84. 2006
    ..The study suggests that upregulation of integrins during exercise enhances neurovascular integrity after stroke. The changes in integrins might be altered by TNF-alpha...
  49. ncbi request reprint Exercise preconditioning reduces brain damage and inhibits TNF-alpha receptor expression after hypoxia/reoxygenation: an in vivo and in vitro study
    Yun Hong Ding
    Department of Neurosurgery, The University of Texas Health Science Center at San Antonio, Mail Code 7843, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    Curr Neurovasc Res 3:263-71. 2006
    ..Chronically increased TNF-alpha expression was also found to reduce TNFI and II responding to acute ischemia/reperfusion insult...
  50. pmc Forced, not voluntary, exercise effectively induces neuroprotection in stroke
    Katherine Hayes
    Department of Neurosurgery, The University of Texas Health Science Center at San Antonio, Mail Code 7843, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    Acta Neuropathol 115:289-96. 2008
    ..This exercise-induced neuroprotection may be attributable to up-regulation of stress-induced heat shock proteins 27 and 70...
  51. ncbi request reprint Early inflammatory response in rat brain after peripheral thermal injury
    Raul Reyes
    Department of Neurosurgery, The University of Texas Health Science Center at San Antonio, Mail Code 7843, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, United States
    Neurosci Lett 407:11-5. 2006
    ..This study demonstrated an early inflammatory response in the brain after severe peripheral thermal injury. The cerebral inflammatory reaction was associated with expression of systemic cytokines and an adhesion molecule...
  52. ncbi request reprint Exercise pre-conditioning ameliorates blood-brain barrier dysfunction in stroke by enhancing basal lamina
    William Davis
    Department of Neurosurgery, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
    Neurol Res 29:382-7. 2007
    ..We investigated whether exercise pre-conditioning ameliorates stroke-induced blood-brain barrier (BBB) dysfunction by strengthening basal lamina...
  53. ncbi request reprint Peripheral thermal injury causes early blood-brain barrier dysfunction and matrix metalloproteinase expression in rat
    Jamie Berger
    Division of Plastic and Reconstructive Surgery, The University of Texas Health Science Center at San Antonio, Floyd C Drive, San Antonio, TX 78229 3900, USA
    Neurol Res 29:610-4. 2007
    ..Our study demonstrated a significant increase in cerebral permeability that occurs after serious systemic thermal injury. The underlying mechanisms could be related to early expression of MMPs...
  54. doi request reprint Preischemic induction of TNF-alpha by physical exercise reduces blood-brain barrier dysfunction in stroke
    Miao Guo
    Department of Neurosurgery, The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    J Cereb Blood Flow Metab 28:1422-30. 2008
    ..These results were negated and returned toward nonexercised values once TNF-alpha or ERK1/2 was blocked. We concluded that preischemic, exercise-induced TNF-alpha markedly decreases BBB dysfunction by using the ERK1/2 pathway...
  55. ncbi request reprint Stroke research in China
    Gangzhi Wei
    Department of Neurology, Xuanwu Hospital, The Capital University of Medical Sciences, Beijing 100053, China
    Neurol Res 28:11-5. 2006
    ....
  56. ncbi request reprint Cerebrovascular injury in stroke
    Yuchuan Ding
    Neurol Res 28:3-10. 2006
  57. ncbi request reprint Spatial accuracy demand in aiming movements: kinematic analysis of subtended angle and tolerance width
    Wan X Yao
    Department of Health and Kinesiology, College of Education and Human Development, The University of Texas at San Antonio, San Antonio, TX 78249, USA
    Percept Mot Skills 104:611-20. 2007
    ..Overall, the results indicate that the tolerance width of the target may impose more constraints on aiming movements than subtended angle...
  58. ncbi request reprint Cortical synaptic arrangements of the third visual pathway in three primate species: Macaca mulatta, Saimiri sciureus, and Aotus trivirgatus
    Yuri Shostak
    Department of Cell Biology, Vanderbilt University, Nashville, Tennessee 37232 2175, USA
    J Neurosci 22:2885-93. 2002
    ..The basic similarities between K axon circuitry within the CO blobs of the three primate species examined also could indicate that this pathway plays some common role or roles across species...
  59. ncbi request reprint Peripheral thermal injury causes blood-brain barrier dysfunction and matrix metalloproteinase (MMP) expression in rat
    Kathryn Swann
    Plastic and Reconstructive Surgery, USA
    Brain Res 1129:26-33. 2007
    ..The increase in MMP-9 expression and activity, associated with increased BBB permeability following thermal injury, indicates that MMP-9 may contribute to observed cerebral edema in peripheral thermal injury...