Research Topics
| Chaoyang ChenSummaryAffiliation: Wayne State University Country: USA Publications
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Detail Information
Publications
Effects of nucleus pulposus on nerve root neural activity, mechanosensitivity, axonal morphology, and sodium channel expressionChaoyang Chen
Spine Research Laboratory, Bioengineering Center, Wayne State University, Detroit, MI 48202, USA
Spine (Phila Pa 1976) 29:17-25. 2004..This study analyzed the effects of autografted nucleus pulposus on nerve root axon morphology, neurophysiologic function, and sodium channel expression...
A new model of traumatic axonal injury to determine the effects of strain and displacement ratesAnita Singh
Bioengineering Center, Wayne State University, MI, USA
Stapp Car Crash J 50:601-23. 2006..In conclusion, the results from this study indicate that the severity of both functional and structural injury increased with increases in strain and displacement rate...
Distribution of A-delta and C-fiber receptors in the cervical facet joint capsule and their response to stretchChaoyang Chen
Bioengineering Center, Wayne State University, 818 West Hancock Avenue, Detroit, MI 48202, USA
J Bone Joint Surg Am 88:1807-16. 2006..The purposes of this study were to determine the distribution of A-delta and C-fiber sensory receptors in the facet joint capsule and to test their patterns of response to stretch and related sensory function...
Recording of neural activity from goat cervical facet joint capsule using custom-designed miniature electrodesChaoyang Chen
Spine Research Laboratory, Bioengineering Center, Wayne State University, Detroit, Michigan 48202, USA
Spine (Phila Pa 1976) 30:1367-72. 2005..To establish a methodology for the neurophysiologic study of mechanoreceptors in the cervical facet joint capsule...
Tensile stretching of cervical facet joint capsule and related axonal changesSrinivasu Kallakuri
Biomedical Engineering, Bioengineering Center, Wayne State University, 818 W Hancock, Detroit, MI 48201, USA
Eur Spine J 17:556-63. 2008..These may contribute to neuropathic pain and are potentially related to neck pain after whiplash events...
Neurophysiological and biomechanical characterization of goat cervical facet joint capsulesYing Lu
Bioengineering Center, Wayne State University, 818 W Hancock, Detroit, MI 48202, USA
J Orthop Res 23:779-87. 2005..8+/-11.4 N/mm. Our results indicate that sensory receptors in cervical facet joint capsules are not only capable of signaling a graded physiological mechanical stimulus, but may also elicit pain sensation under excessive deformation...
Pain generation in lumbar and cervical facet jointsJohn M Cavanaugh
Bioengineering Center, Wayne State University, 818 West Hancock, Detroit, MI 48202, USA
J Bone Joint Surg Am 88:63-7. 2006..In instances in which a whiplash event is severe enough to injure the joint capsule, facet capsule overstretch is a possible cause of persistent neck pain...
Development of an in vivo method to investigate biomechanical and neurophysiological properties of spine facet joint capsulesYing Lu
Bioengineering Center, Wayne State University, Detroit, MI 48202, USA
Eur Spine J 14:565-72. 2005....
Strain and load thresholds for cervical muscle recruitment in response to quasi-static tensile stretch of the caprine C5-C6 facet joint capsuleNadia R Azar
Bioengineering Center, Wayne State University, Detroit, MI, USA
J Electromyogr Kinesiol 19:e387-94. 2009....
The effects of epidural application of allografted nucleus pulposus in rats on cytokine expression, limb withdrawal and nerve root dischargeSrinivasu Kallakuri
Bioengineering Center, Wayne State University, 818 West Hancock, Detroit, MI 48202, USA
Eur Spine J 14:956-64. 2005..05) but not higher than fat and sham rats. These results support the inflammatory nature of NP but offer limited support to NP-mediated thermal behavioral changes...
Mechanical properties of spinal nerve roots subjected to tension at different strain ratesAnita Singh
Bioengineering Center, Wayne State University, 818, W Hancock, Detroit, MI 48202, USA
J Biomech 39:1669-76. 2006..Overall, results from the present study demonstrate viscoelastic material properties of spinal nerve roots and provide better insight on the tensile properties of nerve roots at different strain rates...
Neural response of cervical facet joint capsule to stretch: a study of whiplash pain mechanismYing Lu
Bioengineering Center, Wayne State University, Detroit, MI, 48202, USA
Stapp Car Crash J 49:49-65. 2005..High threshold units likely signal nociception (pain sensation) while afterdischarge may signal capsule strain injury and contribute to persistent pain...
Demonstration of substance P, calcitonin gene-related peptide, and protein gene product 9.5 containing nerve fibers in human cervical facet joint capsulesSrinivasu Kallakuri
Bioengineering Center, Wayne State University, Detroit, MI 48202, USA
Spine (Phila Pa 1976) 29:1182-6. 2004..Human cervical facet joint capsules were evaluated by immunohistochemistry...
The effects of ultrasonic and electrosurgery devices on nerve physiologyChaoyang Chen
Spine Research Laboratory, Department of Biomedical Engineering, Wayne State University, Detroit, MI, USA
Br J Neurosurg 26:856-63. 2012..This study sought to compare the sub-acute neurophysiologic effects of the Harmonic Blade and electrosurgery after incisions close to the sciatic nerve...
Innervation of cervical ventral facet joint capsule: Histological evidenceSrinivasu Kallakuri
Srinivasu Kallakuri, Yan Li, Chaoyang Chen, John M Cavanaugh, Department of Biomedical Engineering, Wayne State University, 818 W Hancock, Detroit, MI 48201, United States
World J Orthop 3:10-4. 2012..To assess the presence of nerves in ventral facet joint capsules as facet capsules are generally implicated in neck pain...
