Research Topics
| Seemant ChaturvediSummaryAffiliation: Wayne State University Country: USA Publications
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Detail Information
Publications
Variability in carotid endarterectomy practice patterns within a metropolitan areaAmit Kansara
Department of Neurology, Wayne State University, 8 C UHC, 4201 St Antoine, Detroit, MI 48201
Stroke 43:3105-7. 2012..The extent to which carotid endarterectomy is still being performed in this group of patients is unclear...
Cerebral angiography practices at US teaching hospitals. Implications for carotid endarterectomyS Chaturvedi
Department of Neurology, Wayne State University Detroit Medical Center, Mich 48201, USA
Stroke 28:1895-7. 1997..How one measures carotid stenosis may affect the applicability of clinical trial results. We sought to obtain information on cerebral angiography practices at teaching hospitals in the United States...- Angioplasty and stenting for stroke prevention: good questions that need answersSeemant Chaturvedi
Department of Neurology and Comprehensive Stroke Program, Wayne State University Detroit Medical Center, Detroit, MI 48201, USA
Neurology 59:664-8. 2002..Angioplasty, with or without stent placement, also offers a potential new therapeutic approach for patients with intracranial stenosis and vertebrobasilar lesions, although these procedures have been performed in uncontrolled fashion... - New insights in antiplatelet therapy for patients with ischemic strokeSeemant Chaturvedi
Department of Neurology and Stroke Program, Wayne State University, Detroit, MI 48210 2153, USA
Neurologist 17:255-62. 2011..Antiplatelet agents currently used in the treatment of ischemic stroke and TIA are aspirin, clopidogrel, and dipyridamole... - Should the multicenter carotid endarterectomy trials be repeated?Seemant Chaturvedi
Department of Neurology, Wayne State University, Detroit, MI 48201, USA
Arch Neurol 60:774-5. 2003 - Carotid artery stenting in octogenarians: periprocedural stroke risk predictor analysis from the multicenter Carotid ACCULINK/ACCUNET Post Approval Trial to Uncover Rare Events (CAPTURE 2) clinical trialSeemant Chaturvedi
Department of Neurology and Stroke Program, Wayne State University, Detroit, MI 48201, USA
Stroke 41:757-64. 2010..The aim of this analysis is to identify risk predictors for periprocedural stroke in patients > or = 80 years old... - The role of antiplatelet therapy in carotid stenting for ischemic stroke preventionSeemant Chaturvedi
Department of Neurology, Wayne State University, Detroit, Michigan 48201, USA
Stroke 37:1572-7. 2006..It is effective and has an acceptable risk profile, but ischemic complications caused by distal embolization and underlying atherothrombosis persist... - Effect of atorvastatin in elderly patients with a recent stroke or transient ischemic attackS Chaturvedi
Stroke Program and Department of Neurology, Wayne State University, Detroit, MI 48201, USA
Neurology 72:688-94. 2009..It is unclear whether patients age 65 years and over with a recent stroke or TIA benefit from statin treatment to a similar degree as younger patients... - Acetylsalicylic acid + extended-release dipyridamole combination therapy for secondary stroke preventionSeemant Chaturvedi
Department of Neurology and Stroke Program, Wayne State University, Detroit, Michigan 48201, USA
Clin Ther 30:1196-205. 2008..Although clinicians may choose acetylsalicylic acid (ASA) as first-line therapy for secondary prevention, clinical guidelines and evidence from trials suggest that ASA may not be the most effective strategy... - Higher risk factor burden and worse outcomes in urban carotid endarterectomy patientsSeemant Chaturvedi
Stroke Program and the Department of Neurology, Wayne State University, Detroit, MI 48201, USA
Stroke 39:2966-8. 2008..We assessed the hypothesis that CEA results from two urban hospitals would approximate those of the previous multicenter trials... - Risk factor status and vascular events in patients with symptomatic intracranial stenosisS Chaturvedi
Stroke Program and Department of Neurology, Wayne State University, 8C UHC, 4201 St Antoine, Detroit, MI 48201, USA
Neurology 69:2063-8. 2007..There are limited data on the relationship between control of vascular risk factors and vascular events in patients with symptomatic intracranial arterial stenosis... - Carotid artery stenting for high-risk patientsSeemant Chaturvedi
Department of Neurology, Wayne State University Detroit Medical Center, MI 48201, USA
Neurol Res 24:S63-5. 2002..The application of stenting in these areas is discussed, as well as the potential role for stenting in patients with acute ischemic stroke... - Circadian variation in ischemic stroke subtypesS Chaturvedi
Department of Neurology, Wayne State University, Detroit, Mich 48201, USA
Stroke 30:1792-5. 1999..The purpose of our study was to define the circadian patterns of symptom onset in an acute stroke trial with an established system for stroke subtype classification... - Coagulation abnormalities in adults with cryptogenic stroke and patent foramen ovaleS Chaturvedi
Department of Neurology Wayne State University Detroit Medical Center 6E UHC, MI 48201, USA
J Neurol Sci 160:158-60. 1998..05). Prothrombotic states are common in patients with PFO and CS and identifying these conditions may impact the choice of antithrombotic therapy... - Multiple hemostatic abnormalities in young adults with activated protein C resistance and cerebral ischemiaS Chaturvedi
Department of Neurology, Wayne State University Detroit Medical Center, MI 48201, USA
J Neurol Sci 159:209-12. 1998..The relationship between activated protein C resistance (APCR) and arterial stroke is uncertain. It has been speculated that multiple inherited or acquired prothrombotic conditions may alter the hemostatic balance towards thrombotic events... - Cerebral angioplasty practice at major medical centers in the United StatesS Chaturvedi
WSU DMC Stroke Program, and Department of Neurology, Wayne State University School of Medicine, Detroit Medical Center, MI 48201, USA
Neuroradiology 42:218-20. 2000..Comparisons with other medical specialties (e.g., cardiologists, neurologists, neurosurgeons) are necessary to determine the full scope of extracranial neurovascular procedures being performed and the corresponding complication rates... - Activated protein C resistance in young African American patients with ischemic strokeS Chaturvedi
Department of Neurology, Wayne State University Detroit Medical Center, MI 48201, USA
J Neurol Sci 163:137-9. 1999..However, this may not be the case for all ethnic groups due to variability in the prevalence of the FVL mutation... - Results of carotid endarterectomy with prospective neurologist follow-upS Chaturvedi
Department of Neurology, Wayne State University Detroit Medical Center, MI 48201, USA
Neurology 55:769-72. 2000..Previous studies have shown that neurologic complications following carotid endarterectomy (CE) are underestimated if patients are not examined by neurologists after surgery... - Is another clinical trial warranted regarding endarterectomy for asymptomatic carotid stenosis?S Chaturvedi
Department of Neurology, Wayne State University Detroit Medical Center, Mich, USA
Cerebrovasc Dis 8:210-3. 1998..These research studies have not resolved the controversy regarding the optimal treatment of patients with this condition... - Protein S deficiency, activated protein C resistance and sticky platelet syndrome in a young woman with bilateral strokesS Chaturvedi
Department of Neurology, Wayne State University School of Medicine Detroit Medical Center, Detroit, Mich 48201, USA
Cerebrovasc Dis 9:127-30. 1999..Coagulation disorders are common in young adults (age less than 55 years) with ischemic stroke... - Carotid endarterectomy: indications for symptomatic and asymptomatic stenosisS Chaturvedi
Department of Neurology and Stroke Program, Wayne State University, 8C UHC, 4201 St Entoine, Detroit, MI 48201, USA
Curr Atheroscler Rep 2:115-9. 2000..This paper outlines the key results for patients with symptomatic and asymptomatic stenosis. A scheme for the identification of patients likely to benefit from surgery, and persistent areas of controversy and uncertainty, are reviewed... - Carotid stent thrombosis: report of 2 fatal casesS Chaturvedi
Department of Neurology and Stroke Program, Wayne State University, Detroit, Michigan, USA
Stroke 32:2700-2. 2001..Carotid stenting is receiving increased attention as an alternative to carotid endarterectomy. Carotid stent thrombosis is a rare complication of this procedure... - Public health impact of carotid endarterectomyS Chaturvedi
Department of Neurology, Wayne State University, Detroit Medical Center, Detroit, Mich 48201, USA
Neuroepidemiology 18:15-21. 1999.... - Predictors of ischemic stroke in the territory of a symptomatic intracranial arterial stenosisScott E Kasner
Department of Neurology, University of Pennsylvania Medical Center, Philadelphia, PA, USA
Circulation 113:555-63. 2006..A prespecified aim of WASID was to identify patients at highest risk for stroke in the territory of the stenotic artery who would be the target group for a subsequent trial comparing intracranial stenting with medical therapy... - Racial differences in vascular risk factors and outcomes of patients with intracranial atherosclerotic arterial stenosisSalina P Waddy
Department of Neurology, Emory University School of Medicine, 101 Woodruff Circle, Atlanta, GA 30322, USA
Stroke 40:719-25. 2009..We analyzed the vascular risk factors and outcomes of blacks and whites in the Warfarin versus Aspirin for Symptomatic Intracranial Disease (WASID) trial... - Prevention of ischemic stroke: surgeryKumar Rajamani
Comprehensive Stroke Program, Department of Neurology, Wayne State University, Detroit, MI 48201, USA
Curr Drug Targets 8:860-6. 2007..The surgical treatment of complete carotid occlusion by EC-IC bypass surgery has also enjoyed renewed interest and results of the COSS study are awaited keenly. The EC-IC bypass surgical procedure is also beneficial in moya-moya disease... - Clinical profiles, complications, and disability in cocaine-related ischemic strokePratik Bhattacharya
Department of Neurology, Wayne State University, Detroit, Michigan, USA
J Stroke Cerebrovasc Dis 20:443-9. 2011..Moreover, because the patients with cocaine-related stroke is younger, they have an earlier morbidity. New strategies for effective stroke prevention interventions are needed in this subgroup... - Arrival by ambulance is associated with acute stroke intervention in young adultsNandakumar Nagaraja
Department of Neurology and Stroke Program, Wayne State University School of Medicine, Detroit, MI 48201, USA
J Neurol Sci 316:168-9. 2012..We hypothesized that arrival to the emergency department by ambulance would be associated with increased rate of stroke intervention with intravenous t-PA or intra arterial procedures... - Safety and efficacy of intracranial stenting for acute ischemic stroke beyond 8 h of symptom onsetAndrew R Xavier
Department of Neurology, Wayne State University, Detroit, Michigan, USA
J Neurointerv Surg 4:94-100. 2012..Background Acute ischemic stroke (AIS) therapy is often limited to an 8 h window using mechanical means. However, recent reports have shown delayed recanalization beyond 8 h might be a viable option in a subset of patients... - Factors associated with misdiagnosis of acute stroke in young adultsAbraham Kuruvilla
Department of Neurology and Stroke Program, Wayne State University Detroit Medical Center, Detroit, MI, USA
J Stroke Cerebrovasc Dis 20:523-7. 2011..Our study demonstrates the increasing need for "young stroke awareness" among emergency department personnel. Initial misdiagnosis can potentially lead to a lost opportunity for thrombolysis in otherwise good candidates... - High rate of inappropriate carotid endarterectomy in an urban medical centerManish Kapadia
Stroke Program and Department of Neurology, Wayne State University, Detroit, Michigan 48201, USA
J Stroke Cerebrovasc Dis 18:277-80. 2009..Some studies have reported that the appropriateness of carotid endarterectomy (CEA) has dramatically improved in the last two decades. However, these studies did not include the most recent study results for asymptomatic stenosis... - Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosisMarc I Chimowitz
Department of Neurology, School of Medicine, Emory University, Atlanta, USA
N Engl J Med 352:1305-16. 2005..Atherosclerotic intracranial arterial stenosis is an important cause of stroke. Warfarin is commonly used in preference to aspirin for this disorder, but these therapies have not been compared in a randomized trial... - Transient ischaemic attacks : new approaches to managementRamesh Madhavan
Department of Neurology and Comprehensive Stroke Program, Wayne State University/Detroit Medical Center, Detroit, Michigan 48201, USA
CNS Drugs 17:293-305. 2003..Recent studies have shown that many patients will benefit from a multimodal pharmacological approach following transient cerebral ischaemia, and the potential for combination therapy is highlighted... - Are racial disparities in stroke care still prevalent in certified stroke centers?Pratik Bhattacharya
Department of Neurology and Stroke Program, Wayne State University School of Medicine, Detroit, Michigan Electronic address
J Stroke Cerebrovasc Dis 22:383-8. 2013..Efforts must be focused on eliminating disparities in prehospital delays. Guideline-based care tendered at JC-certified centers might help narrow disparities in acute stroke care delivery... - Surgery Insight: carotid endarterectomy--which patients to treat and when?Kumar Rajamani
Department of Neurology, Wayne State University, 8C UHC, 4201 St Antoine, Detroit, MI 48201, USA
Nat Clin Pract Cardiovasc Med 4:621-9. 2007.... - New strategies in the medical treatment of carotid artery diseaseKumar Rajamani
Comprehensive Stroke Program and Department of Neurology, Wayne State University, Detroit, MI 48201, USA
Curr Cardiol Rep 8:33-7. 2006..Implementation of these therapies will likely reduce the need for revascularization procedures in the future... - Detection of carotid stenosis in African Americans with ischemic heart diseaseKumar Rajamani
Department of Neurology, Wayne State University, Detroit, MI 48201, USA
J Vasc Surg 43:1162-5. 2006..CONCLUSION: African American patients with established IHD have higher rates of extracranial carotid stenosis than community dwelling African American subjects and comparable rates with other populations... - Comparison of outcomes of nonsurgical spontaneous intracerebral hemorrhage based on risk factors and physician specialtyPratik Bhattacharya
Division of Vascular Neurology, Department of Neurology, Wayne State University, Detroit, Michigan 48201, USA
J Stroke Cerebrovasc Dis 19:340-6. 2010..To our knowledge, there is no reported literature on the effect of physician specialty and outcomes (modified Rankin scale [mRS] score, in-hospital death, and hospital length of stay [LOS])... - Early use of MRI improves diagnostic accuracy in young adults with strokePratik Bhattacharya
Department of Neurology and Stroke Program, Wayne State University, 8D UHC, 4201 St Antoine, Detroit, MI 48201, United States
J Neurol Sci 324:62-4. 2013..We assessed the hypothesis that early use of MRI, arrival by ambulance, and presentation to a Primary Stroke Center (PSC) would be associated with a reduced rate of misdiagnosis... - Thrombolysis for acute ischemic stroke in joint commission-certified and -noncertified hospitals in MichiganKumar Rajamani
Comprehensive Stroke Program, Wayne State University School of Medicine, Detroit, MI 48201, USA
J Stroke Cerebrovasc Dis 22:49-54. 2013..In this study, we focused on the delivery of care for patients with acute ischemic and compared differences in JC-certified and -noncertified centers in Michigan... - Gender based differences in acute stroke care in Michigan hospitalsNandakumar Nagaraja
Department of Neurology and Stroke Program, Wayne State University School of Medicine, Detroit, MI, USA
J Neurol Sci 314:88-91. 2012..We sought to examine whether gender-based differences in acute stroke care occur in both Joint Commission (JC) certified and noncertified hospitals... 
Patent foramen ovale, cardiac valve thickening, and antiphospholipid antibodies as risk factors for subsequent vascular events: the PICSS-APASS studyKumar Rajamani
Department of Neurology, Wayne State University, Detroit, MI 48201, USA
Stroke 40:2337-42. 2009..PFO is associated with cryptogenic ischemic stroke. Also, the presence of aPL is associated with ischemic cerebrovascular disease...- Practice variation among Michigan neurologists in the use of intravenous heparinRashmi Kudesia
Department of Neurology, Wayne State University/Detroit Medical Center, 8C-UHC, 4201 St Antoine, Detroit, MI 48201, USA
J Neurol Sci 202:25-7. 2002..Further studies are necessary to determine whether negative clinical trials have the same impact on neurologist behavior as positive studies... - Factor v leiden mutation in reocclusion after intra-arterial thrombolysisAbraham Kuruvilla
Department of Neurology, WSU DMC Comprehensive Stroke Program, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
Stroke 40:660-2. 2009..Reocclusion of intracranial arteries after successful recanalization is associated with poor clinical outcome. The role of Factor V Leiden mutation in intracranial arterial thrombosis/rethrombosis is unclear... - Why do ischemic stroke and transient ischemic attack patients get readmitted?Pratik Bhattacharya
Department of Neurology, Wayne State University Detroit Medical Center, Detroit, MI 48201, USA
J Neurol Sci 307:50-4. 2011..Readmission is an important indicator for the quality of healthcare services. The authors examined the reasons for 30-day readmission among urban stroke patients, and their clinical consequences... - Implications of the Leapfrog Initiative for carotid endarterectomy in MichiganMohammad F Sunbulli
Department of Neurology and Stroke Program, Wayne State University, Detroit, MI, USA
Neurology 63:590-1. 2004 - Intensive medical therapy for asymptomatic carotid artery stenosisPratik Bhattacharya
Department of Neurology and Stroke Program, Wayne State University, Detroit, MI 48201, USA
Curr Cardiol Rep 13:18-23. 2011..Evidence is accumulating that improved medical therapy has led to a lower risk of stroke in medically treated patients and that ultrasound methods can identify higher-risk patients. These developments are highlighted in this article... - Medical management of carotid artery diseaseKumar Rajamani
Department of Neurology and Stroke Program, Wayne State University/Detroit Medical Center, Detroit, Michigan 48201, USA
Semin Neurol 25:376-83. 2005..Application of this multimodal cocktail holds promise for reducing vascular events in patients with carotid artery disease and may reduce the need for revascularization procedures... - Carotid endarterectomy--an evidence-based review: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of NeurologyS Chaturvedi
Department of Neurology, Wayne State University, USA
Neurology 65:794-801. 2005..Low dose aspirin (81 to 325 mg) is preferred for patients before and after carotid endarterectomy to reduce the rate of stroke, myocardial infarction, and death (Level A)... - Warfarin vs aspirin for symptomatic intracranial stenosis: subgroup analyses from WASIDS E Kasner
Department of Neurology, University of Pennsylvania Medical Center, Philadelphia, PA, USA
Neurology 67:1275-8. 2006.... - Are patients receiving maximal medical therapy following carotid endarterectomy?M Betancourt
Blue Cross and Blue Shield of Michigan Center for Health Care Quality and Evaluative Studies, Detroit, USA
Neurology 63:2011-5. 2004..As vascular event rates can be lowered with statins, antihypertensive agents, and newer antiplatelet agents, the authors conducted a study to determine the usage of these medications in patients following carotid endarterectomy (CE)... - Stroke prevention-surgical and interventional approaches to carotid stenosisKumar Rajamani
Comprehensive Stroke Program, Department of Neurology, Wayne State University School of Medicine, 8C UHC, 4201 St Antoine, Detroit, MI 48201, USA
Neurotherapeutics 8:503-14. 2011..This review focuses on the current data available that will enable the clinician to decide optimal treatment strategies for patients with carotid stenosis... - Anticoagulants and antiplatelet agents in acute ischemic stroke: report of the Joint Stroke Guideline Development Committee of the American Academy of Neurology and the American Stroke Association (a division of the American Heart Association)B M Coull
Department of Neurology, Arizona Health Science Center, Tucson, Ariz, USA
Stroke 33:1934-42. 2002 - Outcomes of carotid endarterectomy in the elderly: report from the National Cardiovascular Data RegistryKumar Rajamani
Wayne State University School of Medicine, Detroit, MI 48201, USA
Stroke 44:1172-4. 2013..Using the Carotid Artery Revascularization and Endarterectomy registry, we sought to determine real-world outcomes of carotid endarterectomy in the elderly... - Use of intravenous heparin by North American neurologists: do the data matter?Ahmad Al-Sadat
Department of Neurology and Comprehensive Stroke Program, Wayne State University, Detroit, Mich 48201, USA
Stroke 33:1574-7. 2002..Our aim was to determine current usage patterns of intravenous heparin for patients with acute ischemic stroke... - Good outcome in HELLP syndrome with lobar cerebral hematomasMahmoud Rayes
Department of Neurology, Wayne State University, Detroit, MI 48201, USA
Neurocrit Care 14:276-80. 2011..HELLP syndrome is associated with high morbidity and mortality which is attributed most commonly to intracranial hemorrhage (ICH) and/or stroke. The presence of other complications further worsens the prognosis... - Usefulness of intravenously administered fluid replenishment for detection of patent foramen ovale by transesophageal echocardiographyLuis Afonso
Division of Cardiology, Wayne State University, Detroit, Michigan, USA
Am J Cardiol 106:1054-8. 2010..In conclusion, saline infusion in appropriately selected patients during transesophageal echocardiography significantly enhances the detection of PFOs and pulmonary arteriovenous fistulas... - Giant arachnoid granulationsMohammed Sunbulli
Department of Neurology and Stroke Program, Wayne State University, 8C-UHC, 4201 St. Antoine, Detroit, MI 48201, USA
Neurology 64:2150. 2005 - Awareness, treatment, and control of vascular risk factors in African Americans with strokeS Ruland
Department of Neurology, Rush University, Chicago, IL 60612, USA
Neurology 60:64-8. 2003..To investigate control of risk factors in African American patients with previous stroke... - Anticoagulants and antiplatelet agents in acute ischemic stroke: report of the Joint Stroke Guideline Development Committee of the American Academy of Neurology and the American Stroke Association (a division of the American Heart Association)B M Coull
Department of Neurology, Arizona Health Science Center, Tucson, AZ, USA
Neurology 59:13-22. 2002 - Perforator stroke following intracranial stenting: a sacrifice for the greater good?Elad I Levy
Neurology 66:1803-4. 2006 - Cryptogenic stroke in relation to genetic variation in clotting factors and other genetic polymorphisms among young men and womenHarland Austin
Division of AIDS, STD, and TB Laboratory Research, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Atlanta, GA, USA
Stroke 33:2762-8. 2002.... - Angioplasty for intracranial atherosclerosis: is the treatment worse than the disease?Seemant Chaturvedi
Neurology 61:1647-8. 2003 - Prevalence and prognosis of coexistent asymptomatic intracranial stenosisFadi Nahab
Stroke 39:1039-41. 2008..5%, 95% CI: 0.8% to 9.0%). CONCLUSIONS: Whereas the prevalence of coexisting AIS (50% to 99%) in patients with symptomatic stenosis is high, the risk of stroke from these asymptomatic stenoses is low... - Has evidence changed practice? Appropriateness of carotid endarterectomy after the clinical trialsSeemant Chaturvedi
Neurology 69:224; author reply 224-5. 2007 - Should stroke be considered both a brain attack and a heart attack?Seemant Chaturvedi
Stroke 38:1713-4. 2007 - Relationship between blood pressure and stroke recurrence in patients with intracranial arterial stenosisTanya N Turan
Emory University, Atlanta, GA, USA
Circulation 115:2969-75. 2007..Many clinicians allow blood pressure to run high in patients with intracranial stenosis to protect against hypoperfusion. We sought to determine whether higher blood pressure decreases the risk of stroke in these patients...