Cathryn Hufford Bock

Summary

Affiliation: Wayne State University
Country: USA

Publications

  1. ncbi request reprint Prostate cancer early detection practices among men with a family history of disease
    Cathryn H Bock
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor 48109 0946, USA
    Urology 62:470-5. 2003
  2. pmc Grilled meat consumption and PhIP-DNA adducts in prostate carcinogenesis
    Deliang Tang
    Environmental Health Science, Columbia University Mailman School of Public Health, 630 W 168th Street, P and S 19 407, New York, NY, USA
    Cancer Epidemiol Biomarkers Prev 16:803-8. 2007
  3. ncbi request reprint NQO1 T allele associated with decreased risk of later age at diagnosis lung cancer among never smokers: results from a population-based study
    C H Bock
    Population Studies and Prevention Program, Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA
    Carcinogenesis 26:381-6. 2005
  4. ncbi request reprint Decreasing age at prostate cancer diagnosis over successive generations in prostate cancer families
    Cathryn H Bock
    Wayne State University School of Medicine, Karmanos Cancer Institute, Detroit, Michigan 48201, USA
    Prostate 64:60-6. 2005
  5. pmc Prostate cancer risk from occupational exposure to polycyclic aromatic hydrocarbons interacting with the GSTP1 Ile105Val polymorphism
    Benjamin A Rybicki
    Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, MI 48202, USA
    Cancer Detect Prev 30:412-22. 2006
  6. pmc Results from a prostate cancer admixture mapping study in African-American men
    Cathryn Hufford Bock
    Wayne State University School of Medicine, Detroit, MI 48201, USA
    Hum Genet 126:637-42. 2009
  7. pmc SRD5A2 and HSD3B2 polymorphisms are associated with prostate cancer risk and aggressiveness
    Christine Neslund-Dudas
    Department of Biostatistics and Research Epidemiology, Henry Ford Hospital, Detroit, MI 48202, USA
    Prostate 67:1654-63. 2007
  8. pmc Evidence supports a faster growth rate and/or earlier transformation to clinically significant prostate cancer in black than in white American men, and influences racial progression and mortality disparity
    Isaac J Powell
    Wayne State University School of Medicine and Karmanos Cancer Institute, Detroit, Michigan, USA
    J Urol 183:1792-6. 2010
  9. pmc Racial differences in risk of prostate cancer associated with metabolic syndrome
    Jennifer L Beebe-Dimmer
    Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, Michiga 48201 1379, USA
    Urology 74:185-90. 2009
  10. ncbi request reprint Sexually transmitted diseases and other urogenital conditions as risk factors for prostate cancer: a case--control study in Wayne County, Michigan
    Divya A Patel
    Karmanos Cancer Institute, Wayne State University, Detroit, MI 48109 0276, USA
    Cancer Causes Control 16:263-73. 2005

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Prostate cancer early detection practices among men with a family history of disease
    Cathryn H Bock
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor 48109 0946, USA
    Urology 62:470-5. 2003
    ....
  2. pmc Grilled meat consumption and PhIP-DNA adducts in prostate carcinogenesis
    Deliang Tang
    Environmental Health Science, Columbia University Mailman School of Public Health, 630 W 168th Street, P and S 19 407, New York, NY, USA
    Cancer Epidemiol Biomarkers Prev 16:803-8. 2007
    ..Our results suggest that dietary interventions targeted at lower consumption of grilled red meats may reduce prostate cancer risk via the PhIP prostate carcinogenic pathway...
  3. ncbi request reprint NQO1 T allele associated with decreased risk of later age at diagnosis lung cancer among never smokers: results from a population-based study
    C H Bock
    Population Studies and Prevention Program, Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA
    Carcinogenesis 26:381-6. 2005
    ..The observed risk reductions may be attributable to the greatly reduced procarcinogen activating of NAD(P)H:quinone oxidoreductase 1 in individuals with at least one copy of the T allele...
  4. ncbi request reprint Decreasing age at prostate cancer diagnosis over successive generations in prostate cancer families
    Cathryn H Bock
    Wayne State University School of Medicine, Karmanos Cancer Institute, Detroit, Michigan 48201, USA
    Prostate 64:60-6. 2005
    ..The decline in age at prostate cancer diagnosis over the past decade is partially attributable to prostate specific antigen (PSA) screening. We examined age at diagnosis over successive generations within prostate cancer families...
  5. pmc Prostate cancer risk from occupational exposure to polycyclic aromatic hydrocarbons interacting with the GSTP1 Ile105Val polymorphism
    Benjamin A Rybicki
    Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, MI 48202, USA
    Cancer Detect Prev 30:412-22. 2006
    ..An Ile/Val polymorphism in codon 105 of GSTP1 affects its enzymatic activity toward PAH detoxification, a possible mechanism in prostate carcinogenesis...
  6. pmc Results from a prostate cancer admixture mapping study in African-American men
    Cathryn Hufford Bock
    Wayne State University School of Medicine, Detroit, MI 48201, USA
    Hum Genet 126:637-42. 2009
    ..In conclusion, we confirmed ancestry associations on 8q24, and identified additional ancestry-associated regions potentially harboring prostate cancer susceptibility loci...
  7. pmc SRD5A2 and HSD3B2 polymorphisms are associated with prostate cancer risk and aggressiveness
    Christine Neslund-Dudas
    Department of Biostatistics and Research Epidemiology, Henry Ford Hospital, Detroit, MI 48202, USA
    Prostate 67:1654-63. 2007
    ..Two polymorphisms, a valine (V) for leucine (L) substitution at the 89 codon of the SRD5A2 gene and a (TG)n,(TA)n,(CA)n repeat polymorphism within the third intron of the HSD3B2 gene were evaluated with regard to prostate cancer risk...
  8. pmc Evidence supports a faster growth rate and/or earlier transformation to clinically significant prostate cancer in black than in white American men, and influences racial progression and mortality disparity
    Isaac J Powell
    Wayne State University School of Medicine and Karmanos Cancer Institute, Detroit, Michigan, USA
    J Urol 183:1792-6. 2010
    ..We propose that a more rapid prostate cancer growth rate and/or earlier transformation from latent to aggressive prostate cancer in black than in white men contribute to this disparity...
  9. pmc Racial differences in risk of prostate cancer associated with metabolic syndrome
    Jennifer L Beebe-Dimmer
    Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, Michiga 48201 1379, USA
    Urology 74:185-90. 2009
    ..A number of recent reports have linked metabolic syndrome to prostate cancer; however, most studies have not had racially diverse populations to explore differences in risk...
  10. ncbi request reprint Sexually transmitted diseases and other urogenital conditions as risk factors for prostate cancer: a case--control study in Wayne County, Michigan
    Divya A Patel
    Karmanos Cancer Institute, Wayne State University, Detroit, MI 48109 0276, USA
    Cancer Causes Control 16:263-73. 2005
    ....
  11. pmc Polycyclic aromatic hydrocarbon--DNA adducts in prostate and biochemical recurrence after prostatectomy
    Benjamin A Rybicki
    Departments of Biostatistics and Research Epidemiology and Surgical Pathology, Henry Ford Health System, Detroit, Michigan 48202, USA
    Clin Cancer Res 14:750-7. 2008
    ..DNA adduct levels may be influenced by metabolic activity, DNA repair capabilities, and genomic integrity, all of which play a role in cancer progression...
  12. ncbi request reprint The molecular epidemiology of lung cancer
    Ann G Schwartz
    Population Studies and Prevention Program, Karmanos Cancer Institute, and Department of Internal Medicine, Wayne State University School of Medicine, 110 E Warren Avenue, Detroit, MI 48103, USA
    Carcinogenesis 28:507-18. 2007
    ..In the future, studies that focus on complex interactions between multiple genes and environmental exposures within pertinent pathways are needed. New technological advances in genotyping will help move the field forward...
  13. pmc Associations between smoking, polymorphisms in polycyclic aromatic hydrocarbon (PAH) metabolism and conjugation genes and PAH-DNA adducts in prostate tumors differ by race
    Nora L Nock
    Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, USA
    Cancer Epidemiol Biomarkers Prev 16:1236-45. 2007
    ..2363 +/- 0.0132 versus 0.1920 +/- 0.0157; P= 0.05). We present evidence, for the first time in human prostate that the association between smoking and PAH-DNA adducts differs by race and is modified by common genetic variants...
  14. pmc Racial differences in clinical and pathological associations with PhIP-DNA adducts in prostate
    Deliang Tang
    Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, NY, USA
    Int J Cancer 121:1319-24. 2007
    ..In conclusion, while PhIP-DNA adduct levels in prostate cells do not vary significantly by race, our results suggest that PhIP exposure may have stronger effects on prostate tumor differentiation in African-American men...
  15. ncbi request reprint Association between family history of prostate and breast cancer among African-American men with prostate cancer
    Jennifer L Beebe-Dimmer
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan 48109 0946, USA
    Urology 68:1072-6. 2006
    ..To explore the familial aggregation of prostate and breast cancer using data from a population-based case-control study of African-American men participating in the Flint Men's Health Study...
  16. ncbi request reprint Association between Agent Orange and prostate cancer: a pilot case-control study
    Veda Nargund Giri
    Department of Internal Medicine, Division of Hematology Oncology, University of Michigan Medical School, Ann Arbor, Michigan 48109 0946, USA
    Urology 63:757-60; discussion 760-1. 2004
    ..Prostate cancer is the most common cancer diagnosed in American men and the second leading cause of cancer deaths. An association between Agent Orange and prostate cancer has been suggested by epidemiologic studies...

Research Grants2