George J Alangaden

Summary

Affiliation: Wayne State University
Country: USA

Publications

  1. ncbi Aspergillosis: The most common community-acquired pneumonia with gram-negative Bacilli as copathogens in stem cell transplant recipients with graft-versus-host disease
    George J Alangaden
    Division of Infectious Diseases, Wayne State University School of Medicine, Karmanos Cancer Institute, and The Detroit Medical Center, Detroit, MI, USA
    Clin Infect Dis 35:659-64. 2002
  2. doi Molecular characterisation of cyp51A and cyp51B genes coding for P450 14alpha-lanosterol demethylases A (CYP51Ap) and B (CYP51Bp) from voriconazole-resistant laboratory isolates of Aspergillus flavus
    Suganthini Krishnan-Natesan
    Division of Infectious Diseases, Department of Medicine, Wayne State University, Detroit, MI 48201, USA
    Int J Antimicrob Agents 32:519-24. 2008
  3. ncbi Sirolimus exposure during the early post-transplant period reduces the risk of CMV infection relative to tacrolimus in renal allograft recipients
    Abdolreza Haririan
    Division of Nephrology, Department of Medicine, Wayne State Uinversity School of Medicine, Detroit, MI, USA
    Clin Transplant 21:466-71. 2007
  4. ncbi Novel effect of voriconazole on conidiation of Aspergillus species
    Neeraja L Varanasi
    Department of Medicine, Wayne State University, 427 Lande Building, 550 E Canfield, Detroit, MI 48201, USA
    Int J Antimicrob Agents 23:72-9. 2004
  5. pmc Recent epidemiology of Clostridium difficile infection during hematopoietic stem cell transplantation
    Teena Chopra
    Division of Infectious Diseases, Wayne State University, Detroit, MI, USA
    Clin Transplant 25:E82-7. 2011
  6. doi A comparison of the fungicidal activity of amphotericin B and posaconazole against Zygomycetes in vitro
    Suganthini Krishnan-Natesan
    Department of Medicine, Division of Infectious Diseases, Wayne State University, John D Dingell VA Medical Center, Detroit, MI, USA
    Diagn Microbiol Infect Dis 63:361-4. 2009
  7. ncbi Fluvastatin potentiates the activity of caspofungin against Aspergillus fumigatus in vitro
    Suganthini Krishnan Natesan
    Department of Internal Medicine Division of Infectious Diseases, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Diagn Microbiol Infect Dis 60:369-73. 2008
  8. ncbi Treatment of resistant enterococcal urinary tract infections
    Subramanian Swaminathan
    Division of Infectious Diseases, Wayne State University School of Medicine, Detroit, MI, USA
    Curr Infect Dis Rep 12:455-64. 2010
  9. doi Nosocomial fungal infections: epidemiology, infection control, and prevention
    George J Alangaden
    Division of Infectious Diseases, Wayne State University, 3990 John R, Suite 5930, Detroit, MI 48201, USA
    Infect Dis Clin North Am 25:201-25. 2011
  10. ncbi Differential activity of triazoles in two-drug combinations with the echinocandin caspofungin against Aspergillus fumigatus
    Elias K Manavathu
    Division of Infectious Diseases, Department of Medicine, Wayne State University, 427 Lande Building, 550 E Canfield, Detroit, MI 48201, USA
    J Antimicrob Chemother 51:1423-5. 2003

Collaborators

Detail Information

Publications15

  1. ncbi Aspergillosis: The most common community-acquired pneumonia with gram-negative Bacilli as copathogens in stem cell transplant recipients with graft-versus-host disease
    George J Alangaden
    Division of Infectious Diseases, Wayne State University School of Medicine, Karmanos Cancer Institute, and The Detroit Medical Center, Detroit, MI, USA
    Clin Infect Dis 35:659-64. 2002
    ..Aspergillosis is the most common cause of community-acquired pneumonia among allogeneic HSCT recipients with GVHD. CT must be used to exclude an underlying fungal cause in patients who present with a gram-negative pneumonia...
  2. doi Molecular characterisation of cyp51A and cyp51B genes coding for P450 14alpha-lanosterol demethylases A (CYP51Ap) and B (CYP51Bp) from voriconazole-resistant laboratory isolates of Aspergillus flavus
    Suganthini Krishnan-Natesan
    Division of Infectious Diseases, Department of Medicine, Wayne State University, Detroit, MI 48201, USA
    Int J Antimicrob Agents 32:519-24. 2008
    ..flavus isolates can be readily isolated in the laboratory under selection pressure. Multiple mechanisms, including drug target modification, may be responsible for the in vitro resistance of A. flavus to VCZ...
  3. ncbi Sirolimus exposure during the early post-transplant period reduces the risk of CMV infection relative to tacrolimus in renal allograft recipients
    Abdolreza Haririan
    Division of Nephrology, Department of Medicine, Wayne State Uinversity School of Medicine, Detroit, MI, USA
    Clin Transplant 21:466-71. 2007
    ..We examined the association between exposure to sirolimus (SRL) and risk of CMV infection after kidney transplantation when compared with tacrolimus (TCL)...
  4. ncbi Novel effect of voriconazole on conidiation of Aspergillus species
    Neeraja L Varanasi
    Department of Medicine, Wayne State University, 427 Lande Building, 550 E Canfield, Detroit, MI 48201, USA
    Int J Antimicrob Agents 23:72-9. 2004
    ....
  5. pmc Recent epidemiology of Clostridium difficile infection during hematopoietic stem cell transplantation
    Teena Chopra
    Division of Infectious Diseases, Wayne State University, Detroit, MI, USA
    Clin Transplant 25:E82-7. 2011
    ..Prospective studies to better define the epidemiology and identify unique risk factors for CDI and more accurate tests to confirm the diagnosis in this population are needed...
  6. doi A comparison of the fungicidal activity of amphotericin B and posaconazole against Zygomycetes in vitro
    Suganthini Krishnan-Natesan
    Department of Medicine, Division of Infectious Diseases, Wayne State University, John D Dingell VA Medical Center, Detroit, MI, USA
    Diagn Microbiol Infect Dis 63:361-4. 2009
    ....
  7. ncbi Fluvastatin potentiates the activity of caspofungin against Aspergillus fumigatus in vitro
    Suganthini Krishnan Natesan
    Department of Internal Medicine Division of Infectious Diseases, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Diagn Microbiol Infect Dis 60:369-73. 2008
    ..9% killing of A. fumigatus conidia, whereas either drug alone showed poor activity at subinhibitory concentrations. FST potentiated the antifungal activity of CFG but displayed no specific interaction with voriconazole or amphotericin B...
  8. ncbi Treatment of resistant enterococcal urinary tract infections
    Subramanian Swaminathan
    Division of Infectious Diseases, Wayne State University School of Medicine, Detroit, MI, USA
    Curr Infect Dis Rep 12:455-64. 2010
    ..Aminoglycosides or rifampin may be considered as adjunctive therapy in serious infections...
  9. doi Nosocomial fungal infections: epidemiology, infection control, and prevention
    George J Alangaden
    Division of Infectious Diseases, Wayne State University, 3990 John R, Suite 5930, Detroit, MI 48201, USA
    Infect Dis Clin North Am 25:201-25. 2011
    ..Recently published recommendations and guidelines for the control and prevention of these nosocomial fungal infections are summarized...
  10. ncbi Differential activity of triazoles in two-drug combinations with the echinocandin caspofungin against Aspergillus fumigatus
    Elias K Manavathu
    Division of Infectious Diseases, Department of Medicine, Wayne State University, 427 Lande Building, 550 E Canfield, Detroit, MI 48201, USA
    J Antimicrob Chemother 51:1423-5. 2003
    ..The in vitro susceptibility of A. fumigatus to two-drug combinations of itraconazole, voriconazole, posaconazole and ravuconazole with caspofungin was evaluated by the fractional inhibitory concentration index (FICI) method...
  11. pmc Detection of oseltamivir resistance during treatment of 2009 H1N1 influenza virus infection in immunocompromised patients: utility of cycle threshold values of qualitative real-time reverse transcriptase PCR
    Tejal Mehta
    Division of Infectious Diseases, Beaumont Hospital, Detroit, Michigan 48201, USA
    J Clin Microbiol 48:4326-8. 2010
    ..Oseltamivir resistance was later confirmed by pyrosequencing...
  12. doi Clostridium difficile infection in cancer patients and hematopoietic stem cell transplant recipients
    Teena Chopra
    Division of Infectious Diseases, Wayne State University, Detroit, MI 48201, USA
    Expert Rev Anti Infect Ther 8:1113-9. 2010
    ..The purpose of this article is to describe the epidemiology, pathogenesis and management of CDI in patients receiving cancer chemotherapeutic agents, and in hematopoietic stem cell transplant recipients...
  13. doi Immediate cross-hypersensitivity between micafungin and caspofungin: a case report
    Shruti Patel
    Wayne State University, Detroit, MI, USA
    J Oncol Pharm Pract 15:187-9. 2009
    ..It is recommended to avoid challenging patients with history of immediate hypersensitivity to one echinocandin with another...
  14. ncbi Infectious complications after kidney transplantation: current epidemiology and associated risk factors
    George J Alangaden
    Division of Infectious Diseases, Department of Internal Medicine, Wayne State University School of Medicine, Detroit, MI, USA
    Clin Transplant 20:401-9. 2006
    ..The impact of newer immunosuppressive and antimicrobial prophylactic agents on the pattern of infectious complications following kidney transplantation has not been well studied...
  15. ncbi Resistance to amphotericin B does not emerge during treatment for invasive aspergillosis
    Mahomed Yunus S Moosa
    Division of Infectious Diseases, Department of Internal Medicine, Wayne State University School of Medicine, Detroit, MI 48201, USA
    J Antimicrob Chemother 49:209-13. 2002
    ..Laboratory attempts to produce amphotericin B resistance in Aspergillus were unsuccessful. These data indicate that emergence of resistance to amphotericin B is uncommon during therapy for invasive aspergillosis...