A R Zazulia

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. pmc Poor correlation between perihematomal MRI hyperintensity and brain swelling after intracerebral hemorrhage
    Allyson R Zazulia
    Department of Neurology and Neurological Surgery, Washington University School of Medicine, 660 S Euclid Avenue, Campus Box 8111, St Louis, MO 63110, USA
    Neurocrit Care 15:436-41. 2011
  2. pmc Autoregulation of cerebral blood flow to changes in arterial pressure in mild Alzheimer's disease
    Allyson R Zazulia
    Department of Neurology, Washington University, St Louis, Missouri 63110, USA
    J Cereb Blood Flow Metab 30:1883-9. 2010
  3. doi request reprint Transient focal increase in perihematomal glucose metabolism after acute human intracerebral hemorrhage
    Allyson R Zazulia
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Stroke 40:1638-43. 2009
  4. ncbi request reprint Progression of mass effect after intracerebral hemorrhage
    A R Zazulia
    Departments of Neurology and Neurological Surgery, Lillian Strauss Institute for Neuroscience of the Jewish Hospital of St Louis, MO, USA
    Stroke 30:1167-73. 1999
  5. ncbi request reprint Autoregulation of cerebral blood flow surrounding acute (6 to 22 hours) intracerebral hemorrhage
    W J Powers
    Department of Neurology and Neurological Surgery, Lillian Strauss Institute for Neuroscience, Washington University School of Medicine, St Louis, MO 631101, USA
    Neurology 57:18-24. 2001
  6. ncbi request reprint No reduction in cerebral metabolism as a result of early moderate hyperventilation following severe traumatic brain injury
    M N Diringer
    Department of Neurology and Neurological Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosurg 92:7-13. 2000
  7. ncbi request reprint Mannitol bolus preferentially shrinks non-infarcted brain in patients with ischemic stroke
    T O Videen
    Department of Neurology and Neurological Surgery, Washington University School of Medicine, St Louis, MO, USA
    Neurology 57:2120-2. 2001
  8. ncbi request reprint Hypoperfusion without ischemia surrounding acute intracerebral hemorrhage
    A R Zazulia
    Department of Neurology and Neurological Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA
    J Cereb Blood Flow Metab 21:804-10. 2001
  9. ncbi request reprint Effect of normal saline bolus on cerebral blood flow in regions with low baseline flow in patients with vasospasm following subarachnoid hemorrhage
    Sarah C Jost
    Department of Neurology, Neurological Surgery, and Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosurg 103:25-30. 2005
  10. ncbi request reprint Effect of hyperoxia on cerebral metabolic rate for oxygen measured using positron emission tomography in patients with acute severe head injury
    Michael N Diringer
    Department of Neurology, Neurology Neurosurgery Intensive Care Unit, Barnes Jewish Hospital, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosurg 106:526-9. 2007

Research Grants

Detail Information

Publications23

  1. pmc Poor correlation between perihematomal MRI hyperintensity and brain swelling after intracerebral hemorrhage
    Allyson R Zazulia
    Department of Neurology and Neurological Surgery, Washington University School of Medicine, 660 S Euclid Avenue, Campus Box 8111, St Louis, MO 63110, USA
    Neurocrit Care 15:436-41. 2011
    ..We therefore investigated the relationship between the changes in PHH and the changes in hemispheric brain volume as a measure of edema during the first week after ICH...
  2. pmc Autoregulation of cerebral blood flow to changes in arterial pressure in mild Alzheimer's disease
    Allyson R Zazulia
    Department of Neurology, Washington University, St Louis, Missouri 63110, USA
    J Cereb Blood Flow Metab 30:1883-9. 2010
    ..30, 95% CI=-7.7 to 2.7). The absence of significant change in CBF with a 10 to 15 mm Hg reduction in MAP within the normal autoregulatory range demonstrates that there is neither a generalized nor local defect of autoregulation in AD...
  3. doi request reprint Transient focal increase in perihematomal glucose metabolism after acute human intracerebral hemorrhage
    Allyson R Zazulia
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Stroke 40:1638-43. 2009
    ....
  4. ncbi request reprint Progression of mass effect after intracerebral hemorrhage
    A R Zazulia
    Departments of Neurology and Neurological Surgery, Lillian Strauss Institute for Neuroscience of the Jewish Hospital of St Louis, MO, USA
    Stroke 30:1167-73. 1999
    ..Our goal was to determine the time course and cause for progression of mass effect after ICH...
  5. ncbi request reprint Autoregulation of cerebral blood flow surrounding acute (6 to 22 hours) intracerebral hemorrhage
    W J Powers
    Department of Neurology and Neurological Surgery, Lillian Strauss Institute for Neuroscience, Washington University School of Medicine, St Louis, MO 631101, USA
    Neurology 57:18-24. 2001
    ..The authors undertook this study to provide further information on the changes in whole-brain and periclot regional CBF that occur with pharmacologic reductions in mean arterial pressure (MAP) in patients with acute ICH...
  6. ncbi request reprint No reduction in cerebral metabolism as a result of early moderate hyperventilation following severe traumatic brain injury
    M N Diringer
    Department of Neurology and Neurological Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosurg 92:7-13. 2000
    ..The authors tested the hypothesis that moderate hyperventilation induced early after TBI would not produce a reduction in CBF severe enough to cause cerebral energy failure (CBF that is insufficient to meet metabolic needs)...
  7. ncbi request reprint Mannitol bolus preferentially shrinks non-infarcted brain in patients with ischemic stroke
    T O Videen
    Department of Neurology and Neurological Surgery, Washington University School of Medicine, St Louis, MO, USA
    Neurology 57:2120-2. 2001
    ..1 +/- 2.8 mL (0.6%, p < 0.005). Brain in the noninfarcted hemisphere shrank more (0.8 +/- 0.4%) than in the infarcted hemisphere (0.0 +/- 0.5%, p < 0.05)...
  8. ncbi request reprint Hypoperfusion without ischemia surrounding acute intracerebral hemorrhage
    A R Zazulia
    Department of Neurology and Neurological Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA
    J Cereb Blood Flow Metab 21:804-10. 2001
    ..Thus, the authors found no evidence for ischemia in the periclot zone of hypoperfusion in acute ICH patients studied 5 to 22 hours after hemorrhage onset...
  9. ncbi request reprint Effect of normal saline bolus on cerebral blood flow in regions with low baseline flow in patients with vasospasm following subarachnoid hemorrhage
    Sarah C Jost
    Department of Neurology, Neurological Surgery, and Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosurg 103:25-30. 2005
    ..The purpose of this study was to examine the effects of volume expansion on regional (r)CBF in patients with DIND following SAH...
  10. ncbi request reprint Effect of hyperoxia on cerebral metabolic rate for oxygen measured using positron emission tomography in patients with acute severe head injury
    Michael N Diringer
    Department of Neurology, Neurology Neurosurgery Intensive Care Unit, Barnes Jewish Hospital, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosurg 106:526-9. 2007
    ....
  11. pmc Red blood cell transfusion increases cerebral oxygen delivery in anemic patients with subarachnoid hemorrhage
    Rajat Dhar
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Stroke 40:3039-44. 2009
    ..However, the cerebral response to transfusion remains uncertain, because higher hemoglobin may increase viscosity and further impair cerebral blood flow (CBF) in the setting of vasospasm...
  12. pmc Cerebral hemodynamic and metabolic effects of equi-osmolar doses mannitol and 23.4% saline in patients with edema following large ischemic stroke
    Michael N Diringer
    Departments of Neurology and Neurological Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Neurocrit Care 14:11-7. 2011
    ....
  13. ncbi request reprint Symptomatic autoregulatory failure in acute ischemic stroke
    Allyson R Zazulia
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neurology 68:389-90. 2007
  14. ncbi request reprint Hourly blood pressure monitoring after intravenous tissue plasminogen activator for ischemic stroke: does everyone need it?
    Venkatesh Aiyagari
    Department of Neurology, Washington University School of Medicine, Campus Box 8111, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Stroke 35:2326-30. 2004
    ..We postulated that patients whose BP is not initially elevated are unlikely to have elevated BP later and, therefore, may not need prolonged BP monitoring...
  15. ncbi request reprint Hyponatremia in neurologic patients: consequences and approaches to treatment
    Michael N Diringer
    Department of Neurology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Neurologist 12:117-26. 2006
    ..Hyponatremia is a common fluid-electrolyte disturbance, particularly in patients with neurologic disorders, in part because of the major role the central nervous system (CNS) plays in the regulation of sodium and water homeostasis...
  16. ncbi request reprint Osmotic therapy: fact and fiction
    Michael N Diringer
    Neurology Neurosurgery Intensive Care Unit and Stroke Research Center, Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neurocrit Care 1:219-33. 2004
    ....
  17. ncbi request reprint Regional cerebrovascular and metabolic effects of hyperventilation after severe traumatic brain injury
    Michael N Diringer
    Department of Neurology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosurg 96:103-8. 2002
    ..In the present study they sought to determine if hyperventilation lowers CBF below the ischemic threshold of 18 to 20 ml/100 g/ min in any brain region and if those reductions cause energy failure (defined as a fall in CMRO2)...
  18. ncbi request reprint The use of positron emission tomography in cerebrovascular disease
    William J Powers
    Department of Neurology, Neurological Surgery, and Radiology, East Building Imaging Center, Room 2218F, Campus Box 8225, Washington University School of Medicine, 4525 Scott Avenue, St Louis, MO 63110, USA
    Neuroimaging Clin N Am 13:741-58. 2003
    ..Whether the role of PET expands to impact the management of individual patients will depend on the results of investigations like the Carotid Occlusion Surgery Study that directly assess the ability of PET to influence patient outcome...
  19. ncbi request reprint Early mortality following spontaneous intracerebral hemorrhage
    J A Zurasky
    Neurology Neurosurgery Intensive Care Unit, Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neurology 64:725-7. 2005
    ..Brain death was more common in African Americans, whereas life-sustaining interventions were withdrawn or limited early more often in whites...
  20. ncbi request reprint Factors predicting prognosis after decompressive hemicraniectomy for hemispheric infarction
    A A Rabinstein
    Department of Neurology, University of Miami School of Medicine, Miami, FL, USA
    Neurology 67:891-3. 2006
    ..On multivariate analysis, older age independently predicted poor recovery (odds ratio 2.9 per 10-year increase in age)...
  21. ncbi request reprint Hydrocephalus: a previously unrecognized predictor of poor outcome from supratentorial intracerebral hemorrhage
    M N Diringer
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Stroke 29:1352-7. 1998
    ..The purpose of this study was to determine whether the presence of hydrocephalus after ICH would predict mortality and functional outcome...
  22. pmc Autoregulation after ischaemic stroke
    William J Powers
    Department of Neurology, University of North Carolina School of Medicine, North Carolina 27599 7025, USA
    J Hypertens 27:2218-22. 2009
    ..Data from human participants have failed to resolve the question whether cerebral blood flow (CBF) in the peri-infarct region will decrease due to impaired autoregulation when systemic mean arterial pressure (MAP) is rapidly reduced...
  23. ncbi request reprint Hydrocephalus in ICH: what do we really know?
    Allyson R Zazulia
    Neurocrit Care 8:233-4. 2008

Research Grants1

  1. MECHANISMS OF SECONDARY INJURY IN CEREBRAL HEMORRHAGE
    ALLYSON ZAZULIA; Fiscal Year: 2007
    ..These hypotheses will be tested using sequential PET or MRI studies in 60 patients with acute ICH. ..