Zhongsheng You

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. pmc CtIP links DNA double-strand break sensing to resection
    Zhongsheng You
    Department of Cell Biology and Physiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Mol Cell 36:954-69. 2009
  2. pmc PCNA promotes processive DNA end resection by Exo1
    Xiaoqing Chen
    Department of Cell Biology and Physiology, Washington University School of Medicine, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Nucleic Acids Res 41:9325-38. 2013
  3. doi request reprint DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints
    Zhongsheng You
    Department of Cell Biology and Physiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Trends Cell Biol 20:402-9. 2010

Collaborators

Detail Information

Publications3

  1. pmc CtIP links DNA double-strand break sensing to resection
    Zhongsheng You
    Department of Cell Biology and Physiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Mol Cell 36:954-69. 2009
    ..Thus, CtIP facilitates the transition from DSB sensing to processing: it does so by binding to the DNA at DSBs after DSB sensing and ATM activation and then promoting DNA resection, leading to checkpoint activation and HR...
  2. pmc PCNA promotes processive DNA end resection by Exo1
    Xiaoqing Chen
    Department of Cell Biology and Physiology, Washington University School of Medicine, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Nucleic Acids Res 41:9325-38. 2013
    ..This role of PCNA in DNA resection is analogous to its function in DNA replication where PCNA serves as a processivity co-factor for DNA polymerases. ..
  3. doi request reprint DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints
    Zhongsheng You
    Department of Cell Biology and Physiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Trends Cell Biol 20:402-9. 2010
    ..It does so by regulating the initiation of DSB end resection after integrating signals from the DNA damage checkpoint response and cell cycle cues...