John W Wright

Summary

Affiliation: Washington State University
Country: USA

Publications

  1. doi request reprint The brain renin-angiotensin system: a diversity of functions and implications for CNS diseases
    John W Wright
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Pflugers Arch 465:133-51. 2013
  2. ncbi request reprint Differences in spatial learning comparing transgenic p75 knockout, New Zealand Black, C57BL/6, and Swiss Webster mice
    John W Wright
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Behav Brain Res 153:453-8. 2004
  3. ncbi request reprint Influence of hippocampectomy on habituation, exploratory behavior, and spatial memory in rats
    John W Wright
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Brain Res 1023:1-14. 2004
  4. pmc Contributions of matrix metalloproteinases to neural plasticity, habituation, associative learning and drug addiction
    John W Wright
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Neural Plast 2009:579382. 2009
  5. doi request reprint The brain RAS and Alzheimer's disease
    John W Wright
    Departments of Psychology, Veterinary and Comparative, Anatomy, Pharmacology and Physiology, and Programs in Neuroscience and Biotechnology, Washington State University, Pullman, Pullman, WA 99164 4820, USA
    Exp Neurol 223:326-33. 2010
  6. ncbi request reprint Habituation of the head-shake response induces changes in brain matrix metalloproteinases-3 (MMP-3) and -9
    John W Wright
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Behav Brain Res 174:78-85. 2006
  7. doi request reprint Habituation-induced neural plasticity in the hippocampus and prefrontal cortex mediated by MMP-3
    John W Wright
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, United States
    Behav Brain Res 203:27-34. 2009
  8. ncbi request reprint Pathways involved in the transition from hypertension to hypertrophy to heart failure. Treatment strategies
    John W Wright
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Heart Fail Rev 13:367-75. 2008
  9. doi request reprint The angiotensin AT4 receptor subtype as a target for the treatment of memory dysfunction associated with Alzheimer's disease
    John W Wright
    Department of Psychology, Veterinary and Comparative Anatomy, Pharmacology, and Physiology, Washington State University, P O Box 644820, Pullman, WA 99164 4820, USA
    J Renin Angiotensin Aldosterone Syst 9:226-37. 2008
  10. doi request reprint Brain renin-angiotensin--a new look at an old system
    John W Wright
    Department of Psychology, Washington State University, P O Box 644820, Pullman, WA 99164 4820, USA
    Prog Neurobiol 95:49-67. 2011

Collaborators

Detail Information

Publications43

  1. doi request reprint The brain renin-angiotensin system: a diversity of functions and implications for CNS diseases
    John W Wright
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Pflugers Arch 465:133-51. 2013
    ....
  2. ncbi request reprint Differences in spatial learning comparing transgenic p75 knockout, New Zealand Black, C57BL/6, and Swiss Webster mice
    John W Wright
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Behav Brain Res 153:453-8. 2004
    ..On the other hand, these results do not support the use of the NZB mouse as an animal model of human learning disability and dementia...
  3. ncbi request reprint Influence of hippocampectomy on habituation, exploratory behavior, and spatial memory in rats
    John W Wright
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Brain Res 1023:1-14. 2004
    ..These results question the hypothesis that habituation is solely mediated by the hippocampus in favor of a process that utilizes different brain structures and degrees of neural plasticity dependent upon task requirements...
  4. pmc Contributions of matrix metalloproteinases to neural plasticity, habituation, associative learning and drug addiction
    John W Wright
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Neural Plast 2009:579382. 2009
    ....
  5. doi request reprint The brain RAS and Alzheimer's disease
    John W Wright
    Departments of Psychology, Veterinary and Comparative, Anatomy, Pharmacology and Physiology, and Programs in Neuroscience and Biotechnology, Washington State University, Pullman, Pullman, WA 99164 4820, USA
    Exp Neurol 223:326-33. 2010
    ..These efforts have resulted in a small molecule with desirable hydrophobicity characteristics that shows promise with respect to memory facilitation when peripherally administered...
  6. ncbi request reprint Habituation of the head-shake response induces changes in brain matrix metalloproteinases-3 (MMP-3) and -9
    John W Wright
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Behav Brain Res 174:78-85. 2006
    ..However, cues present in the test environment appear to have provoked elevations in MMP-3 and -9 independent of those accompanying habituation...
  7. doi request reprint Habituation-induced neural plasticity in the hippocampus and prefrontal cortex mediated by MMP-3
    John W Wright
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, United States
    Behav Brain Res 203:27-34. 2009
    ..These results suggest that elevations in hippocampus and prefrontal cortex MMP-3 expression contribute to this simplest form of learning and may be a mechanism underlying spontaneous recovery...
  8. ncbi request reprint Pathways involved in the transition from hypertension to hypertrophy to heart failure. Treatment strategies
    John W Wright
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Heart Fail Rev 13:367-75. 2008
    ..In addition, treatment strategies are discussed, focusing on middle aged and elderly hypertensive and heart failure patients...
  9. doi request reprint The angiotensin AT4 receptor subtype as a target for the treatment of memory dysfunction associated with Alzheimer's disease
    John W Wright
    Department of Psychology, Veterinary and Comparative Anatomy, Pharmacology, and Physiology, Washington State University, P O Box 644820, Pullman, WA 99164 4820, USA
    J Renin Angiotensin Aldosterone Syst 9:226-37. 2008
    ..We conclude with a working hypothesis concerning the importance of the AT4 receptor subtype as a new potential drug target for the treatment of Alzheimer's disease-associated memory loss...
  10. doi request reprint Brain renin-angiotensin--a new look at an old system
    John W Wright
    Department of Psychology, Washington State University, P O Box 644820, Pullman, WA 99164 4820, USA
    Prog Neurobiol 95:49-67. 2011
    ..The development of blood-brain barrier penetrant AT(4) receptor agonists and antagonists is of major importance regarding the continuing evaluation of the efficacy of new treatment approaches...
  11. ncbi request reprint The brain angiotensin system and extracellular matrix molecules in neural plasticity, learning, and memory
    John W Wright
    Department of Psychology, Washington State University, P O Box 644820, Pullman, WA 99164 4820, USA
    Prog Neurobiol 72:263-93. 2004
    ....
  12. ncbi request reprint Neural plasticity and the brain renin-angiotensin system
    John W Wright
    Department of Psychology and Program in Neuroscience, Washington State University, PO Box 644820, Pullman, WA 99164 4820, USA
    Neurosci Biobehav Rev 26:529-52. 2002
    ..These findings generally support an important contribution by angiotensin peptides to neural plasticity and memory consolidation...
  13. ncbi request reprint Conversion of brain angiotensin II to angiotensin III is critical for pressor response in rats
    John W Wright
    Department of Psychology, Washington State University, Pullman, Washington 99164 4820, USA
    Am J Physiol Regul Integr Comp Physiol 284:R725-33. 2003
    ..These results suggest that the brain AT(1) receptor may be designed to preferentially respond to ANG III, and ANG III's importance as a centrally active ligand has been underestimated...
  14. ncbi request reprint Ethanol-induced impairment of spatial memory and brain matrix metalloproteinases
    John W Wright
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Brain Res 963:252-61. 2003
    ..Thus, ethanol-induced impairment in the acquisition of spatial memory tasks may, in part, be due to disruption of brain MMP activity...
  15. ncbi request reprint Ethanol-induced suppression of LTP can be attenuated with an angiotensin IV analog
    John W Wright
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Regul Pept 113:49-56. 2003
    ..These results suggest that an AT(4) receptor agonist is effective in overcoming ethanol's suppressing influence on LTP, and encourage further investigation of the cognitive enhancing properties of such compounds...
  16. ncbi request reprint Introduction: aminopeptidases and hypertension-mechanisms of action and therapeutic strategies
    John W Wright
    Stadium Way, Pullman, 99164 4820, USA
    Heart Fail Rev 13:271-2. 2008
  17. pmc Evaluation of metabolically stabilized angiotensin IV analogs as procognitive/antidementia agents
    Alene T McCoy
    Department of Veterinary and Comparative Anatomy, Pharmacology, and Physiology, P O Box 6520, Washington State University, Pullman, WA 99164 6520, USA
    J Pharmacol Exp Ther 344:141-54. 2013
    ..These data suggest that dihexa may have therapeutic potential as a treatment of disorders, such as Alzheimer's disease, where augmented synaptic connectivity may be beneficial...
  18. ncbi request reprint Effects of extracellular matrix-degrading proteases matrix metalloproteinases 3 and 9 on spatial learning and synaptic plasticity
    Starla E Meighan
    Department of Veterinary Comparative Anatomy, Pharmacology and Physiology, Washington State University, Pullman, Washington 99164, USA
    J Neurochem 96:1227-41. 2006
    ..Together these results indicate that changes in MMP function are critical to synaptic plasticity and hippocampal-dependent learning...
  19. doi request reprint Influence of dorsal hippocampal lesions and MMP inhibitors on spontaneous recovery following a habituation/classical conditioning head-shake task
    Roberta V Wiediger
    Department of Psychology, Lincoln Land Community College, Springfield, IL 62794, USA
    Neurobiol Learn Mem 92:504-11. 2009
    ..Thus, it appears that the dorsal hippocampus influences habituation by conserving responses and reducing spontaneous recovery when a temporally contingent signaling cue is present...
  20. doi request reprint The role of the AT4 and cholinergic systems in the Nucleus Basalis Magnocellularis (NBM): effects on spatial memory
    Wendy L Wilson
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Brain Res 1272:25-31. 2009
    ..These findings suggest a functional role for both the cholinergic and AT(4) receptor systems in spatial learning, and indicate for the first time a functional role for the AngIV/AT(4) receptor system in the NBM...
  21. ncbi request reprint Effects of matrix metalloproteinase inhibition on short- and long-term plasticity of schaffer collateral/CA1 synapses
    Peter C Meighan
    Department of Veterinary Comparative Anatomy, Washington State University, Pullman, Washington 99164, USA
    J Neurochem 102:2085-96. 2007
    ..Together, these data support a generalized role for MMPs in short-term and long-term hippocampal plasticity and indicate that MMPs are a necessary facet of integrin-mediated cell adhesion supporting LTP stabilization...
  22. ncbi request reprint Roles of brain angiotensins II and III in thirst and sodium appetite
    Wendy L Wilson
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Brain Res 1060:108-17. 2005
    ..However, these results do not resolve the primary question of whether conversion of AngII to AngIII is a prerequisite to dipsogenic and salt appetite responses in the brain...
  23. ncbi request reprint Extracellular matrix molecules, long-term potentiation, memory consolidation and the brain angiotensin system
    John W Wright
    Department of Psychology, Washington State University, PO Box 644820, Pullman, WA 99164 4820, USA
    Peptides 23:221-46. 2002
    ..These enzymatic pathways appear to be very important to an understanding of dysfunctional memory diseases such as Alzheimer's disease, multiple sclerosis, brain tumors, and infections...
  24. pmc Facilitation of hippocampal synaptogenesis and spatial memory by C-terminal truncated Nle1-angiotensin IV analogs
    Caroline C Benoist
    Department of Veterinary and Comparative, Washington State University, Pullman, Washington 99164 6520, USA
    J Pharmacol Exp Ther 339:35-44. 2011
    ..These data suggest that the procognitive activity of these molecules is attributable to their ability to augment synaptic connectivity...
  25. doi request reprint Development of angiotensin IV analogs as hepatocyte growth factor/Met modifiers
    Leen H Kawas
    Department of Veterinary and Comparative, Anatomy, Pharmacology, and Physiology, PO Box 6520, Washington State University, Pullman, WA 99164 6520, USA
    J Pharmacol Exp Ther 340:539-48. 2012
    ....
  26. ncbi request reprint Norleucine1-Angiotensin IV alleviates mecamylamine-induced spatial memory deficits
    Mikel L Olson
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Peptides 25:233-41. 2004
    ..These findings support the importance of the AT4 receptor in cognitive processing and suggest that the ability of Nle1-Ang IV to improve spatial memory deficiencies may be dependant upon the brain cholinergic system...
  27. ncbi request reprint Role of mitogen-activated protein kinases during recovery from head-shake response habituation in rats
    Eric S Murphy
    Department of Psychology, University of Alaska Anchorage, 3211 Providence Drive, Anchorage, AK 99508, USA
    Brain Res 1050:170-9. 2005
    ....
  28. ncbi request reprint REM sleep deprivation attenuates actin-binding protein cortactin: a link between sleep and hippocampal plasticity
    Christopher J Davis
    Department of Psychology, Washington State University, Pullman, WA 99164 6520, USA
    Neurosci Lett 400:191-6. 2006
    ..Thus, these data support a functional link between REMS and cytoskeletal reorganization in the hippocampus, a process that is essential for synaptic plasticity...
  29. pmc Inhibition of hippocampal matrix metalloproteinase-3 and -9 disrupts spatial memory
    John W Wright
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Neural Plast 2007:73813. 2007
    ....
  30. doi request reprint Effects of suprachiasmatic nucleus lesions on habituation of the head-shake response
    Kelby L Holtfreter
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Neurosci Lett 439:203-7. 2008
    ..The present findings suggest that the SCN may mediate temporal patterning of spontaneous recovery from habituation and is necessary in order to appropriately reset the animal to its pre-habituation level of responsiveness...
  31. ncbi request reprint Hippocampal MMP-3 elevation is associated with passive avoidance conditioning
    Mikel L Olson
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Regul Pept 146:19-25. 2008
    ..These findings suggest that increased hippocampal MMP-3 expression is an event that may play an important role in synaptic plasticity and memory consolidation...
  32. ncbi request reprint Brain angiotensinergic activity: the state of our current knowledge
    Robert C Speth
    Program in Neuroscience, Dept Veterinary and Comparative Anatomy, Physiology and Pharmacology, Washington State University, P O Box 646520, Pullman, WA 99164 6520, USA
    Proc West Pharmacol Soc 46:11-5. 2003
  33. doi request reprint Mimics of the dimerization domain of hepatocyte growth factor exhibit anti-Met and anticancer activity
    Leen H Kawas
    Department of Veterinary and Comparative, Anatomy, Pharmacology, and Physiology, Washington State University, Pullman, WA 99164 6520, USA
    J Pharmacol Exp Ther 339:509-18. 2011
    ....
  34. doi request reprint Increase in matrix metalloproteinase-9 levels in the rat medial prefrontal cortex after cocaine reinstatement of conditioned place preference
    Travis E Brown
    Department of Veterinary and Comparative Anatomy, Physiology and Pharmacology, Washington State University, Pullman, Washington 99164, USA
    Synapse 62:886-9. 2008
    ....
  35. ncbi request reprint REM sleep deprivation-induced deficits in the latency-to-peak induction and maintenance of long-term potentiation within the CA1 region of the hippocampus
    Christopher J Davis
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Brain Res 973:293-7. 2003
    ..This delay in maximal induction, and the degradation of the maintenance phase of LTP, may represent sleep deprivation-induced impairment of the underlying neurochemical mechanisms normally responsible for memory acquisition...
  36. ncbi request reprint Phospholipase C inhibitor U73122 attenuates the dipsogenic response induced by angiotensin II
    Travis E Brown
    Program in Neuroscience, Department of Veterinary and Comparative Anatomy, Pharmacology and Physiology, Washington State University, Pullman, WA, USA
    Proc West Pharmacol Soc 46:61-3. 2003
  37. pmc Angiotensin receptor subtype mediated physiologies and behaviors: new discoveries and clinical targets
    John W Wright
    Department of Psychology, Washington State University, P O Box 644820, Pullman, WA 99164 4820, USA
    Prog Neurobiol 84:157-81. 2008
    ..This review concludes with a consideration of the emerging therapeutic applications suggested by these newly discovered functions of the RAS...
  38. pmc Plasticity associated with escalated operant ethanol self-administration during acute withdrawal in ethanol-dependent rats requires intact matrix metalloproteinase systems
    Alexander W Smith
    Department of Psychology, Washington State University, Pullman, WA 99164 4820, USA
    Neurobiol Learn Mem 96:199-206. 2011
    ..Thus, the present data identified that an intact MMP system is required for the escalated responding that occurs during acute withdrawal in dependent animals and implicate such escalation as a learned response...
  39. pmc Focus on Brain Angiotensin III and Aminopeptidase A in the Control of Hypertension
    John W Wright
    Departments of Psychology and Veterinary and Comparative Anatomy, Pharmacology, and Physiology and Programs in Neuroscience and Biotechnology, Washington State University, P O Box 644820, Pullman, WA 99164 4820, USA
    Int J Hypertens 2012:124758. 2012
    ..We conclude with thoughts concerning future treatment approaches to controlling hypertension and hypotension...
  40. pmc Importance of the brain Angiotensin system in Parkinson's disease
    John W Wright
    Departments of Psychology, Veterinary and Comparative Anatomy, Pharmacology, and Physiology and Programs in Neuroscience and Biotechnology, Washington State University, P O Box 644820, Pullman, WA 99164 4820, USA
    Parkinsons Dis 2012:860923. 2012
    ..Recently, small angiotensin-based blood-brain barrier penetrant mimetics have been developed that activate this HGF/c-Met system. These compounds may offer a new and novel approach to the treatment of Parkinson's disease...
  41. ncbi request reprint Attenuation of scopolamine-induced learning deficits by LVV-hemorphin-7 in rats in the passive avoidance and water maze paradigms
    Anthony L Albiston
    Howard Florey Institute of Experimental Physiology and Medicine, The University of Melbourne, Parkville, VIC 3010, Australia
    Behav Brain Res 154:239-43. 2004
    ..These studies clearly demonstrate that LVV-H7, like Ang IV, is a pharmacologically active AT(4) ligand that attenuates the deleterious effects of scopolamine on learning performance in two different behavioral paradigms...
  42. ncbi request reprint Central pressor actions of aminopeptidase-resistant angiotensin II analogs: challenging the angiotensin III hypothesis
    Ranjita J Kokje
    Department of Pharmacology, School of Pharmacy, University of Mississippi, University, MS 38677, USA
    Hypertension 49:1328-35. 2007
    ..These data do not support The Angiotensin III Hypothesis and suggest that conversion of exogenously applied angiotensin II to angiotensin III is not necessary to cause brain-mediated pressor or dipsogenic responses...
  43. ncbi request reprint New insights into the importance of aminopeptidase A in hypertension
    Shigehiko Mizutani
    Department of Medical Science of Proteases, Nagoya University, Graduate School of Medicine, Nagoya, Japan
    Heart Fail Rev 13:273-84. 2008
    ..Thus, it appears important to consider the relationship among activation of the RAS, circulating levels of AngII, and the availability of APA in hypertensive disorders...