Research Topics
Genomes and Genes | T E WilsonSummaryAffiliation: Washington University School of Medicine Country: USA Publications
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Publications
Efficient processing of DNA ends during yeast nonhomologous end joining. Evidence for a DNA polymerase beta (Pol4)-dependent pathwayT E Wilson
Department of Pathology, Division of Laboratory Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
J Biol Chem 274:23599-609. 1999..Pol4 is thus specifically recruited to perform gap-filling in an NHEJ pathway that must also involve as yet unidentified nucleases...
Identification of the DNA binding site for NGFI-B by genetic selection in yeastT E Wilson
Department of Pathology, Washington University School of Medicine, St. Louis, MO 63110
Science 252:1296-300. 1991..Cotransfection experiments in mammalian cells demonstrated that NGFI-B can activate transcription from the NBRE with or without its putative ligand binding domain...
Yeast DNA ligase IV mediates non-homologous DNA end joiningT E Wilson
Washington University School of Medicine, Division of Laboratory Medicine, Department of Pathology, St Louis, Missouri 63110, USA
Nature 388:495-8. 1997..Thus, S. cerevisiae has two distinct and separate ligation pathways...
Repair of DNA strand breaks by the overlapping functions of lesion-specific and non-lesion-specific DNA 3' phosphatasesJ R Vance
Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109 0602, USA
Mol Cell Biol 21:7191-8. 2001..Taken together, these results demonstrate a clear role for the lesion-specific enzyme, Tpp1, in the repair of a subset of DNA strand breaks...
The orphan receptors NGFI-B and steroidogenic factor 1 establish monomer binding as a third paradigm of nuclear receptor-DNA interactionT E Wilson
Department of Pathology, Washington University School of Medicine, St Louis, Missouri 63110
Mol Cell Biol 13:5794-804. 1993..This monomer-DNA interaction represents a third paradigm of DNA binding by nuclear receptors in addition to direct and inverted dimerization...
Uncoupling of 3'-phosphatase and 5'-kinase functions in budding yeast. Characterization of Saccharomyces cerevisiae DNA 3'-phosphatase (TPP1)J R Vance
Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109-0602, USA
J Biol Chem 276:15073-81. 2001..Repair of transformed dephosphorylated plasmids, and 5'-hydroxyl blocking lesions more generally, likely proceeds by a cycle of base removal and resynthesis...
Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cellsU Grawunder
Washington University School of Medicine, Division of Molecular Oncology, Department of Pathology, St Louis, Missouri 63110, USA
Nature 388:492-5. 1997....
In vivo mutational analysis of the NGFI-A zinc fingersT E Wilson
Department of Pathology, Washington University School of Medicine, St Louis, Missouri 63110
J Biol Chem 267:3718-24. 1992..Surprisingly, not all of the mutations tested significantly impaired NGFI-A-specific DNA binding, suggesting that the function of these zinc fingers is more diverse than previously recognized...
