Research Topics
Species | D B WilsonSummaryAffiliation: Washington University School of Medicine Country: USA Publications
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Detail Information
Publications
Conditional Mutagenesis of Gata6 in SF1-Positive Cells Causes Gonadal-Like Differentiation in the Adrenal Cortex of MiceMarjut Pihlajoki
Box 8208, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, Missouri 63110
Endocrinology 154:1754-67. 2013..Our findings offer genetic proof that GATA6 regulates the differentiation of steroidogenic progenitors into adrenocortical cells...
GATA4 is a critical regulator of gonadectomy-induced adrenocortical tumorigenesis in miceJustyna Krachulec
Department of Pediatrics, Washington University School of Medicine, St Louis Children s Hospital, St Louis, Missouri 63110, USA
Endocrinology 153:2599-611. 2012..We conclude that GATA4 is a key modifier of gonadectomy-induced adrenocortical neoplasia, postovariectomy obesity, and sex steroidogenic cell differentiation...
Review paper: origin and molecular pathology of adrenocortical neoplasmsM Bielinska
Box 8208, Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110, USA
Vet Pathol 46:194-210. 2009..A better understanding of the factors and signaling pathways involved in adrenal tumorigenesis is necessary to develop targeted pharmacologic and genetic therapies...
Cardiomyocyte differentiation by GATA-4-deficient embryonic stem cellsN Narita
Department of Pediatrics, Washington University School of Medicine, St Louis Children s Hospital, MO 63110, USA
Development 124:3755-64. 1997....
Wild-type endoderm abrogates the ventral developmental defects associated with GATA-4 deficiency in the mouseN Narita
Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri 63110, USA
Dev Biol 189:270-4. 1997..We conclude that expression of GATA-4 in endoderm rather than cardiogenic mesoderm is required for ventral morphogenesis...
Cytochrome b5 expression in gonadectomy-induced adrenocortical neoplasms of the domestic ferret (Mustela putorius furo)S Wagner
Department of Pediatrics, Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110, USA
Vet Pathol 45:439-42. 2008..We concluded that cyt b(5) is upregulated during gonadectomy-induced adrenocortical neoplasia and is a marker of androgen synthetic potential in these tumors...
Transcription factor GATA-4 is a marker of anaplasia in adrenocortical neoplasms of the domestic ferret (Mustela putorius furo)R A Peterson
Department of Pediatrics, Box 8208, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA
Vet Pathol 41:446-9. 2004..We conclude that GATA-4 can function as a marker of anaplasia in ferret adrenocortical tumors...
Gonadectomy-induced adrenocortical neoplasia in the domestic ferret (Mustela putorius furo) and laboratory mouseM Bielinska
Department of Pediatrics, Box 8208, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA
Vet Pathol 43:97-117. 2006..Whether such genetic changes contribute to tissue susceptibility to neoplasia in neutered ferrets and mice awaits further study...
Nude mice as a model for gonadotropin-induced adrenocortical neoplasiaM Bielinska
Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri 63110, USA
Endocr Res 30:913-7. 2004..We conclude that high levels of circulating gonadotropins are sufficient to induce adrenocortical tumorigenesis, even in the presence of intact gonads...
Induction of yolk sac endoderm in GATA-4-deficient embryoid bodies by retinoic acidM Bielinska
Department of Pediatrics, Washington University School of Medicine, St Louis, MO 63110, USA
Mech Dev 65:43-54. 1997..That another GATA-binding protein is induced in the absence of GATA-4 suggests that this family of transcription factors plays an important role in yolk sac differentiation...
The gene for transcription factor GATA-6 resides on mouse chromosome 18 and is expressed in myocardium and vascular smooth muscleN Narita
Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri, 63110, USA
Genomics 36:345-8. 1996..The presence of GATA-6 mRNA in vascular smooth muscle suggests that this transcription factor may play a distinctive role in gene expression in this cell type...
