D K Warren

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint The effect of an education program on the incidence of central venous catheter-associated bloodstream infection in a medical ICU
    David K Warren
    Washington University School of Medicine, 660 South Euclid Ave, Campus Box 8052, St Louis, MO 63110, USA
    Chest 126:1612-8. 2004
  2. ncbi request reprint Outcome and attributable cost of ventilator-associated pneumonia among intensive care unit patients in a suburban medical center
    David K Warren
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO 63110, USA
    Crit Care Med 31:1312-7. 2003
  3. ncbi request reprint A multicenter intervention to prevent catheter-associated bloodstream infections
    David K Warren
    Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA
    Infect Control Hosp Epidemiol 27:662-9. 2006
  4. ncbi request reprint Preventing catheter-associated bloodstream infections: a survey of policies for insertion and care of central venous catheters from hospitals in the prevention epicenter program
    David K Warren
    Division of Infectious Diseases, Washington University School of Medicine, Saint Louis, MO 63110, USA
    Infect Control Hosp Epidemiol 27:8-13. 2006
  5. ncbi request reprint Impact of a methicillin-resistant Staphylococcus aureus active surveillance program on contact precaution utilization in a surgical intensive care unit
    David K Warren
    Division of Infectious Diseases, Department of Surgery, Washington University School of Medicine, St Louis, and Barnes Jewish Hospital, St Louis, MO 63110, USA
    Crit Care Med 35:430-4. 2007
  6. ncbi request reprint Cycling empirical antimicrobial agents to prevent emergence of antimicrobial-resistant Gram-negative bacteria among intensive care unit patients
    David K Warren
    Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Crit Care Med 32:2450-6. 2004
  7. ncbi request reprint Epidemiology of methicillin-resistant Staphylococcus aureus colonization in a surgical intensive care unit
    David K Warren
    Division of Infectious Diseases, Washington University School of Medicine, Barnes Jewish Hospital, Saint Louis, MO 63110, USA
    Infect Control Hosp Epidemiol 27:1032-40. 2006
  8. ncbi request reprint An educational intervention to prevent catheter-associated bloodstream infections in a nonteaching, community medical center
    David K Warren
    Washington University School of Medicine, Saint Louis, MO 63110, USA
    Crit Care Med 31:1959-63. 2003
  9. doi request reprint Central nervous system infections: meningitis and brain abscess
    Hitoshi Honda
    Division of Infectious Diseases, Washington University of School of Medicine, 660 South Euclid Avenue, Campus Box, 8051 Saint Louis, MO 63110, USA
    Infect Dis Clin North Am 23:609-23. 2009
  10. ncbi request reprint Nosocomial primary bloodstream infections in intensive care unit patients in a nonteaching community medical center: a 21-month prospective study
    D K Warren
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO 63110, USA
    Clin Infect Dis 33:1329-35. 2001

Research Grants

Detail Information

Publications48

  1. ncbi request reprint The effect of an education program on the incidence of central venous catheter-associated bloodstream infection in a medical ICU
    David K Warren
    Washington University School of Medicine, 660 South Euclid Ave, Campus Box 8052, St Louis, MO 63110, USA
    Chest 126:1612-8. 2004
    ..To determine whether an education initiative could decrease the rate of catheter-associated bloodstream infection...
  2. ncbi request reprint Outcome and attributable cost of ventilator-associated pneumonia among intensive care unit patients in a suburban medical center
    David K Warren
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO 63110, USA
    Crit Care Med 31:1312-7. 2003
    ..To determine the attributable cost of ventilator-associated pneumonia from a hospital-based cost perspective, after adjusting for potential confounders...
  3. ncbi request reprint A multicenter intervention to prevent catheter-associated bloodstream infections
    David K Warren
    Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA
    Infect Control Hosp Epidemiol 27:662-9. 2006
    ..Education-based interventions can reduce the incidence of catheter-associated bloodstream infection. The generalizability of findings from single-center studies is limited...
  4. ncbi request reprint Preventing catheter-associated bloodstream infections: a survey of policies for insertion and care of central venous catheters from hospitals in the prevention epicenter program
    David K Warren
    Division of Infectious Diseases, Washington University School of Medicine, Saint Louis, MO 63110, USA
    Infect Control Hosp Epidemiol 27:8-13. 2006
    ....
  5. ncbi request reprint Impact of a methicillin-resistant Staphylococcus aureus active surveillance program on contact precaution utilization in a surgical intensive care unit
    David K Warren
    Division of Infectious Diseases, Department of Surgery, Washington University School of Medicine, St Louis, and Barnes Jewish Hospital, St Louis, MO 63110, USA
    Crit Care Med 35:430-4. 2007
    ....
  6. ncbi request reprint Cycling empirical antimicrobial agents to prevent emergence of antimicrobial-resistant Gram-negative bacteria among intensive care unit patients
    David K Warren
    Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Crit Care Med 32:2450-6. 2004
    ..To determine the impact of the rotation of antimicrobial agents on the rates of infection, intestinal colonization, and acquisition with antimicrobial-resistant Gram-negative bacteria...
  7. ncbi request reprint Epidemiology of methicillin-resistant Staphylococcus aureus colonization in a surgical intensive care unit
    David K Warren
    Division of Infectious Diseases, Washington University School of Medicine, Barnes Jewish Hospital, Saint Louis, MO 63110, USA
    Infect Control Hosp Epidemiol 27:1032-40. 2006
    ..Methicillin-resistant Staphylococcus aureus (MRSA) is a cause of healthcare-associated infections among surgical intensive care unit (ICU) patients, though transmission dynamics are unclear...
  8. ncbi request reprint An educational intervention to prevent catheter-associated bloodstream infections in a nonteaching, community medical center
    David K Warren
    Washington University School of Medicine, Saint Louis, MO 63110, USA
    Crit Care Med 31:1959-63. 2003
    ..To evaluate the effectiveness of an evidence-based intervention to prevent catheter-associated bloodstream infections among intensive care unit patients at a nonteaching, community hospital...
  9. doi request reprint Central nervous system infections: meningitis and brain abscess
    Hitoshi Honda
    Division of Infectious Diseases, Washington University of School of Medicine, 660 South Euclid Avenue, Campus Box, 8051 Saint Louis, MO 63110, USA
    Infect Dis Clin North Am 23:609-23. 2009
    ..This article reviews the common infectious etiologies of central nervous system infections, especially bacterial meningitis and brain abscess, and their subsequent management in the intensive care unit...
  10. ncbi request reprint Nosocomial primary bloodstream infections in intensive care unit patients in a nonteaching community medical center: a 21-month prospective study
    D K Warren
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO 63110, USA
    Clin Infect Dis 33:1329-35. 2001
    ..The incidence, risk factors, and serious outcomes of bloodstream infections in a nonteaching community hospital were similar to those seen in tertiary-care teaching hospitals...
  11. ncbi request reprint Occurrence of co-colonization or co-infection with vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus in a medical intensive care unit
    David K Warren
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Infect Control Hosp Epidemiol 25:99-104. 2004
    ..To determine the occurrence of co-colonization or co-infection with VRE and MRSA among medical patients requiring intensive care...
  12. ncbi request reprint Attributable cost of catheter-associated bloodstream infections among intensive care patients in a nonteaching hospital
    David K Warren
    Divisions of Infectious Diseases, Washington University School of Medicine, St Louis, MO, USA
    Crit Care Med 34:2084-9. 2006
    ..To determine the attributable cost and length of stay of intensive care unit (ICU)-acquired, catheter-associated bloodstream infections from a hospital-based cost perspective, after adjusting for potential confounders...
  13. ncbi request reprint Catheter-associated bloodstream infections in general medical patients outside the intensive care unit: a surveillance study
    Jonas Marschall
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO 63110, USA
    Infect Control Hosp Epidemiol 28:905-9. 2007
    ..To determine the incidence of central venous catheter (CVC)-associated bloodstream infection (CA-BSI) among patients admitted to general medical wards outside the intensive care unit (ICU)...
  14. pmc Identification of a pseudo-outbreak of Clostridium difficile infection (CDI) and the effect of repeated testing, sensitivity, and specificity on perceived prevalence of CDI
    Marina Litvin
    Department of Medicine, Washington University School of Medicine, Barnes Jewish Hospital, St Louis, Missouri 63110, USA
    Infect Control Hosp Epidemiol 30:1166-71. 2009
    ..difficile on perceived CDI burden, positive predictive value, and false-positive results...
  15. pmc Risk factors associated with methicillin-resistant Staphylococcus aureus colonization on hospital admission among oncology patients
    Adam M Schaefer
    Barnes Jewish Hospital, St Louis, MO, USA
    Am J Infect Control 37:603-5. 2009
    ..Risk factors for any S aureus and MRSA colonization on admission in oncology patients are consistent with previous studies in general populations. In addition, recent chemotherapy as a risk factor is a unique finding in this population...
  16. ncbi request reprint Prevention of hospital infection
    David K Warren
    Division of Infectious Diseases, Washington University School of Medicine, Saint Louis, MO, USA
    Microbes Infect 7:268-74. 2005
    ..These infection-control policies also require the presence of a dedicated group of infection-control practitioners to provide education, collect surveillance data, and oversee the implementation of the local infection-control plan...
  17. ncbi request reprint The changing susceptibilities of methicillin-resistant Staphylococcus aureus at a midwestern hospital: the emergence of "community-associated" MRSA
    Kathleen M McMullen
    Hospital Infection and Epidemiology Department, Barnes Jewish Hospital, St Louis, MO, USA
    Am J Infect Control 37:454-7. 2009
    ..The emergence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has been well described; however, few studies have reviewed long-term hospital-wide data...
  18. ncbi request reprint The epidemiology of vancomycin-resistant Enterococcus colonization in a medical intensive care unit
    David K Warren
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Infect Control Hosp Epidemiol 24:257-63. 2003
    ..To determine the epidemiology of colonization with vancomycin-resistant Enterococcus (VRE) among intensive care unit (ICU) patients...
  19. ncbi request reprint Weekend diagnosis of Escherichia coli urinary tract infection does not predict poor outcome
    J F Echaiz
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO, USA
    Epidemiol Infect 142:1422-4. 2014
    ..The results indicate that indicators of severity of illness are associated with higher mortality in patients with UTI rather than the time of diagnosis...
  20. ncbi request reprint Infection control measures to limit antimicrobial resistance
    D K Warren
    Division of Infectious Diseases, Washington University School of Medicine, Saint Louis, MO, USA
    Crit Care Med 29:N128-34. 2001
    ....
  21. ncbi request reprint The impact of an antibiotic cycling program on empirical therapy for gram-negative infections
    Liana R Merz
    Division of Infectious Diseases, Washington University School of Medicine, Box 8051, 660 S Euclid Ave, Saint Louis, MO 63110, USA
    Chest 130:1672-8. 2006
    ..Therapy cycling empiric antibiotics between various classes may influence bacterial resistance patterns. Understanding the impact of cycling on the appropriate treatment of suspected Gram-negative infections is important...
  22. pmc Strain-relatedness of methicillin-resistant Staphylococcus aureus isolates recovered from patients with repeated infection
    Susan S Huang
    Division of Infectious Diseases, University of California Irvine School of Medicine, Orange, CA 92868, USA
    Clin Infect Dis 46:1241-7. 2008
    ..We found that MRSA infection following initial colonization or infection is caused by the same strain in most cases, suggesting that a single successful attempt at decolonization may prevent the majority of later infection...
  23. pmc Presence of the KPC carbapenemase gene in Enterobacteriaceae causing bacteremia and its correlation with in vitro carbapenem susceptibility
    Jonas Marschall
    Division of Infectious Diseases, Washington University School of Medicine, 660 S Euclid, St Louis, MO 63110, USA
    J Clin Microbiol 47:239-41. 2009
    ..Three (1.2%) out of 243 isolates were bla(KPC) positive. Ertapenem nonsusceptibility had a low positive predictive value...
  24. pmc Hospital-associated Clostridium difficile infection: is it necessary to track community-onset disease?
    Erik R Dubberke
    Washington University School of Medicine, St Louis, Missouri, USA
    Infect Control Hosp Epidemiol 30:332-7. 2009
    ....
  25. ncbi request reprint Ventilator-associated pneumonia in pediatric intensive care unit patients: risk factors and outcomes
    Alexis M Elward
    Division of Infectious Diseases, Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri, USA
    Pediatrics 109:758-64. 2002
    ..To determine the rates, risk factors, and outcomes of ventilator-associated pneumonia in pediatric intensive care unit (PICU) patients...
  26. ncbi request reprint Between community and hospital: healthcare-associated gram-negative bacteremia among hospitalized patients
    Jonas Marschall
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Infect Control Hosp Epidemiol 30:1050-6. 2009
    ....
  27. doi request reprint The epidemiology of recurrent Gram-negative bacteremia in a tertiary-care hospital
    Jonas Marschall
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO 63110, USA
    Diagn Microbiol Infect Dis 66:456-9. 2010
    ..Seventeen (7.1%) of 241 bacteremic patients developed recurrence (median time to recurrence = 44 days; range, 9-217 days). Recurrent and nonrecurrent bacteremic patients did not differ in clinical characteristics and mortality...
  28. pmc Staphylococcus aureus nasal colonization and subsequent infection in intensive care unit patients: does methicillin resistance matter?
    Hitoshi Honda
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Infect Control Hosp Epidemiol 31:584-91. 2010
    ..aureus infection. However, MRSA-colonized patients may have more comorbidities than methicillin-susceptible S. aureus (MSSA)-colonized or noncolonized patients and therefore may be more susceptible to infection on that basis...
  29. pmc The value of infectious diseases consultation in Staphylococcus aureus bacteremia
    Hitoshi Honda
    Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St Louis, MO, USA
    Am J Med 123:631-7. 2010
    ..Staphylococcus aureus bacteremia results in substantial mortality. Infectious diseases specialist consultation can improve adherence to evidence-based management of S. aureus bacteremia, but its effect on mortality is unclear...
  30. pmc Gram-negative bacteraemia in non-ICU patients: factors associated with inadequate antibiotic therapy and impact on outcomes
    Jonas Marschall
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO, USA
    J Antimicrob Chemother 61:1376-83. 2008
    ..A considerable number of gram-negative bacteraemias occur outside intensive care units (ICUs). Inadequate antibiotic therapy in ICUs has been associated with adverse outcomes; however, there are no prospective studies in non-ICU patients...
  31. pmc Detection of methicillin-resistant Staphylococcus aureus directly from nasal swab specimens by a real-time PCR assay
    David K Warren
    Division of Infectious Diseases, Washington University School of Medicine, Campus Box 8051, 660 S Euclid Ave, Saint Louis, MO 63110, USA
    J Clin Microbiol 42:5578-81. 2004
    ....
  32. ncbi request reprint Effect of chlorhexidine/silver sulfadiazine-impregnated central venous catheters in an intensive care unit with a low blood stream infection rate after implementation of an educational program: a before-after trial
    Douglas J E Schuerer
    Department of Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Surg Infect (Larchmt) 8:445-54. 2007
    ..The purpose of this study was to determine if chlorhexidine/silver sulfadiazine-impregnated CVCs could decrease the CR-BSI rate in an intensive care unit (ICU) with a low baseline infection rate...
  33. ncbi request reprint Attributable cost of nosocomial primary bloodstream infection in pediatric intensive care unit patients
    Alexis M Elward
    Departments of Pediatrics, Washington University School of Medicine, St Louis, Missouri, USA
    Pediatrics 115:868-72. 2005
    ..To determine the attributable cost of nosocomial primary bloodstream infections (BSIs) in PICU patients...
  34. pmc Effects of an antibiotic cycling program on antibiotic prescribing practices in an intensive care unit
    Liana R Merz
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Antimicrob Agents Chemother 48:2861-5. 2004
    ..In conclusion, the successful implementation of this cycling protocol increased antibiotic heterogeneity over time in the study unit...
  35. ncbi request reprint Mupirocin resistance in patients colonized with methicillin-resistant Staphylococcus aureus in a surgical intensive care unit
    Jeffrey C Jones
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO 63110, USA
    Clin Infect Dis 45:541-7. 2007
    ..Mupirocin resistance in patients with MRSA has been reported, usually in the context of widespread mupirocin use...
  36. pmc The epidemiology of hematogenous vertebral osteomyelitis: a cohort study in a tertiary care hospital
    Kavita P Bhavan
    Division of Infectious Diseases, Washington University School of Medicine, St, Louis, MO, USA
    BMC Infect Dis 10:158. 2010
    ..Limited data exist regarding hematogenous vertebral osteomyelitis. Our objective was to describe the epidemiology and management of hematogenous vertebral osteomyelitis...
  37. ncbi request reprint Use of hypochlorite solution to decrease rates of Clostridium difficile-associated diarrhea
    Kathleen M McMullen
    Barnes Jewish Hospital, St Louis, MO 63108, USA
    Infect Control Hosp Epidemiol 28:205-7. 2007
    ..One unit instituted enhanced environmental cleaning with a hypochlorite solution in all rooms, whereas the other unit used hypochlorite solution only in rooms of patients with CDAD. The CDAD rates decreased in both units...
  38. pmc Vancomycin resistance has no influence on outcomes of enterococcal bacteriuria
    H N Khair
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO, USA
    J Hosp Infect 85:183-8. 2013
    ..Infections with vancomycin-resistant enterococci (VRE) are a growing concern in hospitals. The impact of vancomycin resistance in enterococcal urinary tract infection is not well-defined...
  39. ncbi request reprint Tuberculin skin testing of physicians at a midwestern teaching hospital: a 6-year prospective study
    D K Warren
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO 63110, USA
    Clin Infect Dis 32:1331-7. 2001
    ..The relationship between TST conversion and birth outside of the United States and BCG vaccination suggests a booster phenomenon rather than true new TST conversions...
  40. ncbi request reprint Factors associated with the treatment of latent tuberculosis infection among health-care workers at a midwestern teaching hospital
    Sunita J Shukla
    Division of Infectious Diseases, Washington University School of Medicine, St Louis, MO 63110, USA
    Chest 122:1609-14. 2002
    ..To assess factors associated with initiating therapy and compliance with treatment for latent tuberculosis infection among health-care workers with positive tuberculin skin test results...
  41. ncbi request reprint Improving methicillin-resistant Staphylococcus aureus surveillance and reporting in intensive care units
    Susan S Huang
    Brigham and Women s Hospital, Channing Laboratory and Infection Control Department, Harvard Medical School, and Harvard Pilgrim Health Care, Boston, MA 02115, USA
    J Infect Dis 195:330-8. 2007
    ..In addition, many assessments underestimate the incidence of acquisition by including prevalent carriers in the at-risk population...
  42. ncbi request reprint Effectiveness of multifaceted hospitalwide quality improvement programs featuring an intervention to remove unnecessary urinary catheters at a tertiary care center in Thailand
    Anucha Apisarnthanarak
    Division of Infectious Diseases, Faculty of Medicine, Thammasart University Hospital, Pratumthani, Thailand
    Infect Control Hosp Epidemiol 28:791-8. 2007
    ..To evaluate the efficacy of a multifaceted hospitalwide quality improvement program that featured an intervention to remind physicians to remove unnecessary urinary catheters...
  43. ncbi request reprint Initial inappropriate urinary catheters use in a tertiary-care center: incidence, risk factors, and outcomes
    Anucha Apisarnthanarak
    Division of Infectious Diseases and Infection Control, Faculty of Medicine, Thamamsart University Hospital, Pratumthani, Thailand
    Am J Infect Control 35:594-9. 2007
    ..To evaluate the epidemiology and outcomes for initiation of inappropriate urinary catheterization (IUC) among hospitalized patients...
  44. ncbi request reprint Prevalence of the use of central venous access devices within and outside of the intensive care unit: results of a survey among hospitals in the prevention epicenter program of the Centers for Disease Control and Prevention
    Michael Climo
    Hunter Holmes McGuire Veteran Affairs Medical Center, Richmond, Virginia 23249, USA
    Infect Control Hosp Epidemiol 24:942-5. 2003
    ..To determine the prevalence of central venous catheter (CVC) use among patients both within and outside the ICU setting...
  45. ncbi request reprint Effectiveness of an educational program to reduce ventilator-associated pneumonia in a tertiary care center in Thailand: a 4-year study
    Anucha Apisarnthanarak
    Division of Infectious Diseases and Infection Control, Faculty of Medicine, Thammasart University Hospital, Pratumthani, Thailand
    Clin Infect Dis 45:704-11. 2007
    ..We sought to determine the long-term effect of an educational program to prevent VAP in a medical ICU (MICU)...
  46. ncbi request reprint Issues relevant to the adoption and modification of hospital infection-control recommendations for avian influenza (H5N1 infection) in developing countries
    Anucha Apisarnthanarak
    Division of Infectious Diseases, Faculty of Medicine, Thammasart University Hospital, Pratumthani, Thailand
    Clin Infect Dis 45:1338-42. 2007
    ....
  47. doi request reprint Impact of knowledge and positive attitudes about avian influenza (H5N1 virus infection) on infection control and influenza vaccination practices of Thai healthcare workers
    Anucha Apisarnthanarak
    Infect Control Hosp Epidemiol 29:472-4. 2008
  48. ncbi request reprint Outbreak of postoperative endophthalmitis in a Thai tertiary care center
    Anucha Apisarnthanarak
    Division of Infectious Disease, Thammasat University Hospital, Pratumthani, Thailand
    Infect Control Hosp Epidemiol 29:564-6. 2008
    ..Multivariate analysis revealed that diabetes mellitus and surgeon A were associated risk factors. Preoperative diabetes mellitus control and the improvement of infection control practices led to the termination of the outbreak...

Research Grants1

  1. Prevention of Catheter-Associated Blood Stream Infections
    David Warren; Fiscal Year: 2007
    ..I will build on the experience outlined in this proposal to establish myself an independent investigator in healthcare epidemiology, studying nosocomial infections and developing interventions to prevent them. [unreadable] [unreadable]..