Affiliation: Washington University School of Medicine
Al Aly Z, Shao J, Lai C, Huang E, Cai J, Behrmann A, et al. Aortic Msx2-Wnt calcification cascade is regulated by TNF-alpha-dependent signals in diabetic Ldlr-/- mice. Arterioscler Thromb Vasc Biol. 2007;27:2589-96 pubmed
..ALP induction was inhibited by Dkk1, an antagonist of paracrine Wnt actions. TNF-alpha promote aortic Msx2-Wnt programs that contribute to aortic calcium accumulation in T2DM. ..