Richard D Todd

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. doi request reprint Predictors of stability of attention-deficit/hyperactivity disorder subtypes from childhood to young adulthood
    Richard D Todd
    Department of Psychiatry, Washington University School of Medicine, Campus Box 8134, 660 S Euclid Avenue, St Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 47:76-85. 2008
  2. doi request reprint Poor utility of the age of onset criterion for DSM-IV attention deficit/hyperactivity disorder: recommendations for DSM-V and ICD-11
    Richard D Todd
    Department of Psychiatry, Division of Child and Adolescent Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    J Child Psychol Psychiatry 49:942-9. 2008
  3. pmc Alcohol consumption indices of genetic risk for alcohol dependence
    Julia D Grant
    Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Biol Psychiatry 66:795-800. 2009
  4. ncbi request reprint Prenatal smoking exposure and dopaminergic genotypes interact to cause a severe ADHD subtype
    Rosalind J Neuman
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Biol Psychiatry 61:1320-8. 2007
  5. pmc Genetic linkage findings for DSM-IV nicotine withdrawal in two populations
    Michele L Pergadia
    Department of Psychiatry, Washington University School of Medicine, Saint Louis, Missouri 63110, USA
    Am J Med Genet B Neuropsychiatr Genet 150:950-9. 2009
  6. ncbi request reprint Gene-environment interactions in the development of combined type ADHD: evidence for a synapse-based model
    Richard D Todd
    Department of Psychiatry, Washington University School of Medicine, Saint Louis, Missouri, USA
    Am J Med Genet B Neuropsychiatr Genet 144:971-5. 2007
  7. doi request reprint An autosomal linkage scan for cannabis use disorders in the nicotine addiction genetics project
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8134, St Louis, MO 63110, USA
    Arch Gen Psychiatry 65:713-21. 2008
  8. pmc Developmental course of autistic social impairment in males
    John N Constantino
    Washington University School of Medicine, St Louis, MO 63110, USA
    Dev Psychopathol 21:127-38. 2009
  9. ncbi request reprint Estimation of prevalence of DSM-IV and latent class-defined ADHD subtypes in a population-based sample of child and adolescent twins
    Rosalind J Neuman
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Twin Res Hum Genet 8:392-401. 2005
  10. ncbi request reprint Intergenerational transmission of subthreshold autistic traits in the general population
    John N Constantino
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Biol Psychiatry 57:655-60. 2005

Collaborators

Detail Information

Publications63

  1. doi request reprint Predictors of stability of attention-deficit/hyperactivity disorder subtypes from childhood to young adulthood
    Richard D Todd
    Department of Psychiatry, Washington University School of Medicine, Campus Box 8134, 660 S Euclid Avenue, St Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 47:76-85. 2008
    ..To determine the 5-year prospective stability of population-based and DSM-IV subtypes of attention-deficit/hyperactivity disorder (ADHD) as well as to explore predictors of stability...
  2. doi request reprint Poor utility of the age of onset criterion for DSM-IV attention deficit/hyperactivity disorder: recommendations for DSM-V and ICD-11
    Richard D Todd
    Department of Psychiatry, Division of Child and Adolescent Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    J Child Psychol Psychiatry 49:942-9. 2008
    ....
  3. pmc Alcohol consumption indices of genetic risk for alcohol dependence
    Julia D Grant
    Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Biol Psychiatry 66:795-800. 2009
    ..A high genetic correlation between these measures would suggest that a continuous measure of consumption may have a useful role in the discovery of genes contributing to dependence risk...
  4. ncbi request reprint Prenatal smoking exposure and dopaminergic genotypes interact to cause a severe ADHD subtype
    Rosalind J Neuman
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Biol Psychiatry 61:1320-8. 2007
    ..We examined the joint effects of genetic and prenatal substance exposures on DSM-IV and population-defined subtypes of ADHD...
  5. pmc Genetic linkage findings for DSM-IV nicotine withdrawal in two populations
    Michele L Pergadia
    Department of Psychiatry, Washington University School of Medicine, Saint Louis, Missouri 63110, USA
    Am J Med Genet B Neuropsychiatr Genet 150:950-9. 2009
    ..Other studies have reported that chromosome 11 may harbor genes associated with various aspects of smoking behavior. This study adds to that literature by highlighting evidence for NW...
  6. ncbi request reprint Gene-environment interactions in the development of combined type ADHD: evidence for a synapse-based model
    Richard D Todd
    Department of Psychiatry, Washington University School of Medicine, Saint Louis, Missouri, USA
    Am J Med Genet B Neuropsychiatr Genet 144:971-5. 2007
    ..The subtype specificity of these findings supports the concept that ADHD is composed of a group of distinct disorders...
  7. doi request reprint An autosomal linkage scan for cannabis use disorders in the nicotine addiction genetics project
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8134, St Louis, MO 63110, USA
    Arch Gen Psychiatry 65:713-21. 2008
    ..Despite accumulating evidence that there is a genetic basis for cannabis use disorders (ie, abuse and dependence), few studies have identified genomic regions that may harbor biological risk and protective factors...
  8. pmc Developmental course of autistic social impairment in males
    John N Constantino
    Washington University School of Medicine, St Louis, MO 63110, USA
    Dev Psychopathol 21:127-38. 2009
    ..Such measurements can serve as reliable indices of phenotypic severity for genetic and neurobiologic studies, and have potential utility for ascertaining incremental response to intervention...
  9. ncbi request reprint Estimation of prevalence of DSM-IV and latent class-defined ADHD subtypes in a population-based sample of child and adolescent twins
    Rosalind J Neuman
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Twin Res Hum Genet 8:392-401. 2005
    ..As clinical samples are most commonly composed of male combined subtypes, the inattentive subtype of both sexes in the general population is an under-treated segment of the general population...
  10. ncbi request reprint Intergenerational transmission of subthreshold autistic traits in the general population
    John N Constantino
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Biol Psychiatry 57:655-60. 2005
    ..Subthreshold autistic social impairments are known to aggregate in the family members of autistic probands; therefore, we conducted this study to examine the intergenerational transmission of such traits in the general population...
  11. pmc Sex and age differences in attention-deficit/hyperactivity disorder symptoms and diagnoses: implications for DSM-V and ICD-11
    Ujjwal P Ramtekkar
    Washington University in St Louis School of Medicine, Saint Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 49:217-28.e1-3. 2010
    ..To examine gender and age differences in attention-deficit/hyperactivity disorder (ADHD) symptom endorsement in a large community-based sample...
  12. pmc Familial aggregation of quantitative autistic traits in multiplex versus simplex autism
    Yamini V Virkud
    Departments of Psychiatry, Washington University, St Louis, Missouri, USA
    Am J Med Genet B Neuropsychiatr Genet 150:328-34. 2009
    ..Characterization of QAT and other endophenotypes among close relatives may be useful for reducing sample heterogeneity in future genetic and neurobiologic studies of autism...
  13. doi request reprint Co-occurrence of motor problems and autistic symptoms in attention-deficit/hyperactivity disorder
    Angela M Reiersen
    Department of Psychiatry Box 8134, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110 1093, USA
    J Am Acad Child Adolesc Psychiatry 47:662-72. 2008
    ..To investigate the relation between parent reports of motor problems and clinically significant autistic symptoms in children with and without attention-deficit/hyperactivity disorder (ADHD)...
  14. ncbi request reprint A systematic evaluation of ADHD and comorbid psychopathology in a population-based twin sample
    Heather E Volk
    Doctoral Program in Public Health Studies, Saint Louis University School of Public Health, St Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 44:768-75. 2005
    ..Clinical and population samples demonstrate that attention-deficit/hyperactivity disorder (ADHD) occurs with other disorders. Comorbid disorder clustering within ADHD subtypes is not well studied...
  15. ncbi request reprint Familial clustering of latent class and DSM-IV defined attention-deficit/hyperactivity disorder (ADHD) subtypes
    Erik R Rasmussen
    Departments of Psychiatry and Genetics, Washington University School of Medicine, St Louis, MO 63110 1093, USA
    J Child Psychol Psychiatry 45:589-98. 2004
    ..Significant clustering of DSM-IV inattentive and combined subtypes, and significant clustering of the same latent classes among siblings was predicted...
  16. ncbi request reprint Autistic traits in a population-based ADHD twin sample
    Angela M Reiersen
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110 1093, USA
    J Child Psychol Psychiatry 48:464-72. 2007
    ..This study assesses whether children with ADHD selected from the general twin population have elevated levels of autistic traits...
  17. ncbi request reprint Association of dopamine, serotonin, and nicotinic gene polymorphisms with methylphenidate response in ADHD
    Hema Tharoor
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Med Genet B Neuropsychiatr Genet 147:527-30. 2008
    ..Further studies including quantitative measures of treatment response are warranted...
  18. pmc Autosomal linkage analysis for cannabis use behaviors in Australian adults
    Arpana Agrawal
    Washington University School of Medicine, Department of Psychiatry, 660 South Euclid Avenue, St Louis, MO 63108, USA
    Drug Alcohol Depend 98:185-90. 2008
    ....
  19. ncbi request reprint Autistic social impairment in the siblings of children with pervasive developmental disorders
    John N Constantino
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8134, St Louis, MO 63110, USA
    Am J Psychiatry 163:294-6. 2006
    ..Sibling recurrence risk in autism has been estimated to be approximately 10%. This study investigated subsyndromal autistic impairments among siblings of probands with pervasive developmental disorders...
  20. ncbi request reprint The Obsessive Compulsive Scale of the Child Behavior Checklist predicts obsessive-compulsive disorder: a receiver operating characteristic curve analysis
    James J Hudziak
    Department of Psychiatry, University of Vermont, Given B229, Burlington, VT 05405, USA
    J Child Psychol Psychiatry 47:160-6. 2006
    ....
  21. pmc Developing a quantitative measure of alcohol consumption for genomic studies on prospective cohorts
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid Avenue, Box 8134, St Louis, Missouri 63110, USA
    J Stud Alcohol Drugs 70:157-68. 2009
    ..The purpose of this study was to develop a quantitative measure of alcohol consumption for gene-mapping studies...
  22. pmc Evidence for shared genetic influences on self-reported ADHD and autistic symptoms in young adult Australian twins
    Angela M Reiersen
    Department of Psychiatry, Washington University in St Louis School of Medicine, St Louis 63110, USA
    Twin Res Hum Genet 11:579-85. 2008
    ..72. Our results suggest that in young adults, a substantial proportion of the genetic influences on self-reported autistic and ADHD symptoms may be shared between the two disorders...
  23. ncbi request reprint Relationship of 5-HTTLPR genotypes and depression risk in the presence of trauma in a female twin sample
    Vesselin M Chorbov
    Department of Psychiatry, Washington University School of Medicine, Saint Louis, Missouri 63110, USA
    Am J Med Genet B Neuropsychiatr Genet 144:830-3. 2007
    ....
  24. ncbi request reprint Reliability and stability of a semistructured DSM-IV interview designed for family studies
    Richard D Todd
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid, Campus Box 8134, St Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 42:1460-8. 2003
    ....
  25. ncbi request reprint Genetic advances in autism hinge on the method of measuring symptoms
    Richard D Todd
    Departments of Psychiatry and Genetics, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Curr Psychiatry Rep 7:133-7. 2005
    ....
  26. ncbi request reprint Psychiatric comorbidity and progression in drug use in adult male twins: implications for the design of genetic association studies
    Alexandre A Todorov
    Department of Psychiatry, Midwest Alcoholism Research Center, Washington University School of Medicine, 660 South Euclid Avenue, Box 8134, St Louis, MO 63110 1502, United States
    Addict Behav 31:948-61. 2006
    ..We use the result of these analyses to show how the use of a particular drug disorder phenotype for selecting cases could impact final sample composition...
  27. ncbi request reprint Comorbidity between ADHD and symptoms of bipolar disorder in a community sample of children and adolescents
    Wendy Reich
    Departments of Genetics and Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Twin Res Hum Genet 8:459-66. 2005
    ..Episodes of possible bipolar disorders as defined by DSM-IV are uncommon in this nonreferred sample. Children and adolescents with ADHD appear to be only modestly at increased risk for bipolar disorders...
  28. ncbi request reprint Rapid quantitative assessment of autistic social impairment by classroom teachers
    John N Constantino
    Program of Occupational Therapy, Washington University in St Louis, 660 S Euclid, Campus Box 8134, St Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 46:1668-76. 2007
    ..In this study, we compared teachers' ratings of autistic symptomatology with those derived from parents, expert clinicians, and trained raters...
  29. ncbi request reprint Collaborative analysis of DRD4 and DAT genotypes in population-defined ADHD subtypes
    Richard D Todd
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Child Psychol Psychiatry 46:1067-73. 2005
    ..The goal of the current study is to test whether population-based ADHD subtypes defined by latent class analysis help resolve issues of variable findings across individual gene association studies...
  30. ncbi request reprint Brief report: autistic traits in twins vs. non-twins--a preliminary study
    Alexander Ho
    Washington University School of Medicine, Saint Louis, MO 63110, USA
    J Autism Dev Disord 35:129-33. 2005
    ..As has been suggested for autism, twin status may incur increased liability to subthreshold autistic symptomatology, particularly in males...
  31. ncbi request reprint Should sluggish cognitive tempo symptoms be included in the diagnosis of attention-deficit/hyperactivity disorder?
    Richard D Todd
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 43:588-97. 2004
    ..To determine the impact of including sluggish cognitive tempo items on the factor and latent class structure of attention-deficit/hyperactivity disorder (ADHD) subtypes in boys and girls...
  32. pmc Do attention deficit/hyperactivity disorder and oppositional defiant disorder influence preschool unintentional injury risk?
    Dawn Lee Garzon
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    Arch Psychiatr Nurs 22:288-96. 2008
    ..This study explores the relationship among preschool attention deficit/hyperactivity disorder (ADHD), oppositional defiant disorder (ODD), injury-risk-taking behavior, and unintentional injury...
  33. ncbi request reprint Replication of the latent class structure of Attention-Deficit/Hyperactivity Disorder (ADHD) subtypes in a sample of Australian twins
    Erik R Rasmussen
    Washington University School of Medicine, St Louis, MO 63110 1093, USA
    J Child Psychol Psychiatry 43:1018-28. 2002
    ..The objective of the current report is to determine if the latent class structure of ADHD subtypes can be replicated in a culturally distinct sample of female and male Australian twins...
  34. ncbi request reprint ADHD medication use in a population-based sample of twins
    Wendy Reich
    Division of Child Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8134, St Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 45:801-7. 2006
    ..To determine treatment patterns for youth attention-deficit/hyperactivity disorder (ADHD) symptoms in a general population sample of 1,610 twins...
  35. ncbi request reprint Comparison of male adolescent-report of attention-deficit/hyperactivity disorder (ADHD) symptoms across two cultures using latent class and principal components analysis
    Erik R Rasmussen
    Washington University School of Medicine, St Louis, MO 63110 1093, USA
    J Child Psychol Psychiatry 43:797-805. 2002
    ..The consistency of adolescent-derived latent classes from two different samples was assessed and these results were then compared to the class structure generated by parent-report ADHD information...
  36. ncbi request reprint Reliability and stability of mothers' reports about their pregnancies with twins
    Wendy Reich
    School of Medicine, Department of Psychiatry, Washington University, Campus Box 8134, 660 South Euclid, St Louis, MO 63110, USA
    Twin Res 6:85-8. 2003
    ..Kappas were equally high for the 47 mothers that were re-interviewed 6 to 18 months later. Mothers show good reliability and stability of reporting about events during pregnancy...
  37. ncbi request reprint Autistic traits in the general population: a twin study
    John N Constantino
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Arch Gen Psychiatry 60:524-30. 2003
    ....
  38. pmc Social and non-social cueing of visuospatial attention in autism and typical development
    John R Pruett
    Department of Psychiatry Child Division, Washington University School of Medicine, Box 8134, 660 S Euclid Avenue, St Louis, MO 63110, USA
    J Autism Dev Disord 41:715-31. 2011
    ..ASD children made more saccades, slowing their reaction times; however, exogenous and endogenous orienting, including gaze cueing, appear intact in ASD...
  39. pmc Genetic linkage to chromosome 22q12 for a heavy-smoking quantitative trait in two independent samples
    Scott F Saccone
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Hum Genet 80:856-66. 2007
    ..Fine mapping of this linkage region may reveal variants contributing to heaviness of smoking, which will lead to a better understanding of the genetic mechanisms underlying nicotine dependence...
  40. ncbi request reprint Validation of a brief quantitative measure of autistic traits: comparison of the social responsiveness scale with the autism diagnostic interview-revised
    John N Constantino
    Department of Psychiatry, Washington University School of Medicine, Saint Louis, Missouri 63110, USA
    J Autism Dev Disord 33:427-33. 2003
    ..Q. and exhibited inter-rater reliability on the order of 0.8. The SRS is a valid quantitative measure of autistic traits, feasible for use in clinical settings and for large-scale research studies of autism spectrum conditions...
  41. ncbi request reprint Discrimination of DSM-IV and latent class attention-deficit/hyperactivity disorder subtypes by educational and cognitive performance in a population-based sample of child and adolescent twins
    Richard D Todd
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 41:820-8. 2002
    ..This report contrasts two ADHD subtyping approaches on the prediction of cognitive function and educational achievement...
  42. pmc Amygdala volume analysis in female twins with major depression
    Melissa A Munn
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110 1093, USA
    Biol Psychiatry 62:415-22. 2007
    ..Furthermore, few of these studies have examined differences in individuals with an onset during childhood or adolescence. This study examined amygdala volume and its potential association with early onset major depression...
  43. doi request reprint Co-occurrence of ADHD and autism spectrum disorders: phenomenology and treatment
    Angela M Reiersen
    Department of Psychiatry, Washington University in St Louis School of Medicine, St Louis, MO 63110 1093, USA
    Expert Rev Neurother 8:657-69. 2008
    ..e., alpha-agonists, selective serotonin reuptake inhibitors and neuroleptics). They may also benefit from social skills therapy, individual and family psychotherapy, behavioral therapy and other nonpharmacologic interventions...
  44. ncbi request reprint Etiology and genetics of early-onset mood disorders
    Richard D Todd
    Division of Child Psychiatry, Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Box 8134, St Louis, MO 63110, USA
    Child Adolesc Psychiatr Clin N Am 11:499-518. 2002
    ..Preliminary studies of adolescent and young adult twins suggest a significant correspondence between the genetic contributions to some regional brain volumes and early-onset mood disorders...
  45. ncbi request reprint Zygosity diagnosis in the absence of genotypic data: an approach using latent class analysis
    Andrew C Heath
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63108, USA
    Twin Res 6:22-6. 2003
    ..In the absence of genotypic data, or as a safeguard against sample duplication, application of LCA for zygosity assignment or confirmation is strongly recommended...
  46. ncbi request reprint Functional selectivity of dopamine receptor agonists. II. Actions of dihydrexidine in D2L receptor-transfected MN9D cells and pituitary lactotrophs
    Jason D Kilts
    Department of Psychiatry, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7160, USA
    J Pharmacol Exp Ther 301:1179-89. 2002
    ..g., "conformational induction" versus "drug-active state selection"), such data are irreconcilable with the widely held view that drugs have "intrinsic efficacy"...
  47. ncbi request reprint Genetics of early onset bipolar affective disorder: are we making progress?
    Richard D Todd
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8134, St Louis, MO 63110, USA
    Curr Psychiatry Rep 4:141-5. 2002
    ..These studies raise the notion that early onset cases may represent a distinct genetic form or forms of manic-depressive illness...
  48. ncbi request reprint Mutation screening of the dopamine D2 receptor gene in attention-deficit hyperactivity disorder subtypes: preliminary report of a research strategy
    Richard D Todd
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Am J Med Genet 114:34-41. 2002
    ..No coding region sequence variations were identified in the DRD2 gene that met our requirements for prevalence to be considered a candidate variant contributing to susceptibility for ADHD...
  49. ncbi request reprint Deficits in reciprocal social behavior in male twins: evidence for a genetically independent domain of psychopathology
    John N Constantino
    Department of Psychiatry, Washington University School of Medicine, Campus Box 8134, 660 South Euclid Avenue, St Louis, MO 63110, USA
    J Am Acad Child Adolesc Psychiatry 42:458-67. 2003
    ....
  50. ncbi request reprint Volumetric reduction in left subgenual prefrontal cortex in early onset depression
    Kelly N Botteron
    Department of Radiology, School of Medicine, Washington University, 660 South Euclid Avenue, Box 8134, St Louis, MO 63110, USA
    Biol Psychiatry 51:342-4. 2002
    ..In this study, the authors test the hypothesis that SGPFC reduction is present in adolescent onset MD, and examine differences in the magnitude of reduction in younger versus older women...
  51. ncbi request reprint Genetic and environmental contributions to the Child Behavior Checklist Obsessive-Compulsive Scale: a cross-cultural twin study
    James J Hudziak
    Department of Psychiatry, University of Vermont, Burlington Vrije University, Amsterdam, The Netherlands
    Arch Gen Psychiatry 61:608-16. 2004
    ..Twin studies of obsessive-compulsive disorder have indicated a significant genetic component to its expression...
  52. ncbi request reprint Validation of population-based ADHD subtypes and identification of three clinically impaired subtypes
    Heather E Volk
    Doctoral Program in Public Health Studies, Saint Louis University School of Public Health, Saint Louis, Missouri, USA
    Am J Med Genet B Neuropsychiatr Genet 141:312-8. 2006
    ..Comorbidity with CD, ODD, or MD does not significantly increase impairment among ADHD subtypes. The mild combined ADHD subtype represents a clinically significant but under-studied form of ADHD...
  53. ncbi request reprint The latent class structure of ADHD is stable across informants
    Robert R Althoff
    Department of Psychiatry, University of Vermont, Burlington, Vermont 05405, United States of America
    Twin Res Hum Genet 9:507-22. 2006
    ..Results from LCA using Dutch twins with the CRS show stability across informants suggesting that more stable phenotypes may be accessible for genotyping using a multi-informant approach...
  54. ncbi request reprint Does the Child Behavior Checklist juvenile bipolar disorder phenotype identify bipolar disorder?
    Heather E Volk
    Doctoral Program in Public Health Studies, Saint Louis University School of Public Health, Saint Louis, Missouri 63110, USA
    Biol Psychiatry 62:115-20. 2007
    ..We tested this hypothesis in a population-based sample...
  55. ncbi request reprint A quantitative trait locus analysis of social responsiveness in multiplex autism families
    Jacqueline A Duvall
    Department of Neurology, University of California, Los Angeles, USA
    Am J Psychiatry 164:656-62. 2007
    ..The authors present the first genome-wide scan for a social endophenotype in autism using the Social Responsiveness Scale, which provides a quantitative measure of autistic-like behavior, primarily focused on social relatedness...
  56. ncbi request reprint Depression and bipolar support alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in children and adolescents
    Joseph T Coyle
    J Am Acad Child Adolesc Psychiatry 42:1494-503. 2003
    ..To focus attention on the critical unmet needs of children and adolescents with mood disorders and to make recommendations for future research and allocation of healthcare resources...
  57. doi request reprint Long-term stability and heritability of telephone interview measures of alcohol consumption and dependence
    Narelle K Hansell
    Genetic Epidemiology Unit, Queensland Institute of Medical Research, Post Office Royal Brisbane Hospital, Queensland, 4029, Australia
    Twin Res Hum Genet 11:287-305. 2008
    ..42 to .51 for dependence and from .31 to .51 for consumption. Consumption was significantly less heritable in the younger Phase 2 cohort (23-39 years) compared to the older Phase 1 cohort (28-90 years)...
  58. pmc Addictions biology: haplotype-based analysis for 130 candidate genes on a single array
    Colin A Hodgkinson
    Laboratory of Neurogenetics, NIAAA, 5625 Fishers Lane, Room 3S32 MSC9412, Rockville, MD 20852 1728, USA
    Alcohol Alcohol 43:505-15. 2008
    ..To develop a panel of markers able to extract full haplotype information for candidate genes in alcoholism, other addictions and disorders of mood and anxiety...
  59. ncbi request reprint Contributions of parental alcoholism, prenatal substance exposure, and genetic transmission to child ADHD risk: a female twin study
    Valerie S Knopik
    Center for Alcohol and Addiction Studies, Department of Community Health, Brown University Medical School, Providence, RI 02912, USA
    Psychol Med 35:625-35. 2005
    ..Little attention, however, has been directed to investigating the roles of genetic transmission and prenatal exposure simultaneously...
  60. pmc Joint analysis of the DRD5 marker concludes association with attention-deficit/hyperactivity disorder confined to the predominantly inattentive and combined subtypes
    Naomi Lowe
    Department of Genetics, Trinity College, Dublin 2, Ireland
    Am J Hum Genet 74:348-56. 2004
    ..The joint analysis showed association with the DRD5 locus (P=.00005; odds ratio 1.24; 95% confidence interval 1.12-1.38). This association appears to be confined to the predominantly inattentive and combined clinical subtypes...
  61. ncbi request reprint Psychosocial variables in children and teens of extended families identified through bipolar affective disorder probands
    Theodore Petti
    Indiana University School of Medicine, Indianapolis, IN, USA
    Bipolar Disord 6:106-14. 2004
    ..home environment? (ii) in frequency and type of offspring life events? and (iii) in social relations and self-perception? and (2) Do children or their parents who do or do not have an affective disorder report differently on these areas?..
  62. ncbi request reprint Glucose metabolism in the amygdala in depression: relationship to diagnostic subtype and plasma cortisol levels
    Wayne C Drevets
    Section on Neuroimaging of Mood and Anxiety Disorders, Molecular Imaging Branch, NIH National Institute of Mental Health, Building 1, Room B3 10, 1 Center Drive, MSC 0135, Bethesda, MD 20892 0135, USA
    Pharmacol Biochem Behav 71:431-47. 2002
    ....
  63. ncbi request reprint Genetic influences on childhood competencies: a twin study
    James J Hudziak
    University of Vermont College of Medicine, Burlington, USA
    J Am Acad Child Adolesc Psychiatry 42:357-63. 2003
    ..To estimate genetic, environmental, and rater contrast influences on parental reports of Activities, Social, School, and Total Competence scales of the Child Behavior Checklist (CBCL)...