Bradley Schlaggar

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. pmc Correlation of CAG repeat length between the maternal and paternal allele of the Huntingtin gene: evidence for assortative mating
    Peg Nopoulos
    Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA
    Behav Brain Funct 7:45. 2011
  2. ncbi request reprint Functional neuroanatomical differences between adults and school-age children in the processing of single words
    Bradley L Schlaggar
    Department of Neurology, Washington University, St Louis, MO 63110, USA
    Science 296:1476-9. 2002
  3. ncbi request reprint Development of neural systems for reading
    Bradley L Schlaggar
    Department of Neurology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Annu Rev Neurosci 30:475-503. 2007
  4. pmc Mapping genetic influences on cortical regionalization
    Bradley L Schlaggar
    Departments of Neurology, Radiology, Pediatrics, and Anatomy and Neurobiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuron 72:499-501. 2011
  5. ncbi request reprint Developmental changes in human cerebral functional organization for word generation
    Timothy T Brown
    Department of Psychology, Washington University in St Louis, St Louis, MO 63130, USA
    Cereb Cortex 15:275-90. 2005
  6. ncbi request reprint Comparison of functional activation foci in children and adults using a common stereotactic space
    Hyunseon Christine Kang
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuroimage 19:16-28. 2003
  7. ncbi request reprint A comparison of analysis of variance and correlation methods for investigating cognitive development with functional magnetic resonance imaging
    Damien A Fair
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Dev Neuropsychol 30:531-46. 2006
  8. ncbi request reprint Comparison of sustained and transient activity in children and adults using a mixed blocked/event-related fMRI design
    Kristin K Wenger
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuroimage 22:975-85. 2004
  9. pmc Defining functional areas in individual human brains using resting functional connectivity MRI
    Alexander L Cohen
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuroimage 41:45-57. 2008
  10. pmc Control networks in paediatric Tourette syndrome show immature and anomalous patterns of functional connectivity
    Jessica A Church
    Department of Neurology, Washington University School of Medicine, St Louis, MS 63110, USA
    Brain 132:225-38. 2009

Research Grants

  1. Development of Orthographic Knowledge: fMRI Studies
    Bradley Schlaggar; Fiscal Year: 2007
  2. DEVELOPMENT OF SKILLED READING: FMRI STUDIES
    Bradley L Schlaggar; Fiscal Year: 2010
  3. DEVELOPMENT OF SKILLED READING: FMRI STUDIES
    Bradley L Schlaggar; Fiscal Year: 2010

Collaborators

Detail Information

Publications34

  1. pmc Correlation of CAG repeat length between the maternal and paternal allele of the Huntingtin gene: evidence for assortative mating
    Peg Nopoulos
    Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA
    Behav Brain Funct 7:45. 2011
    ..The current study shows a significant correlation between the CAG repeat length of the maternal and paternal allele in the Huntingtin gene among healthy subjects, suggesting assortative mating...
  2. ncbi request reprint Functional neuroanatomical differences between adults and school-age children in the processing of single words
    Bradley L Schlaggar
    Department of Neurology, Washington University, St Louis, MO 63110, USA
    Science 296:1476-9. 2002
    ..Some of the brain regions examined showed differences attributable to age independent of performance, suggesting that maturation of the pattern of regional activations for these tasks is incomplete at age 10...
  3. ncbi request reprint Development of neural systems for reading
    Bradley L Schlaggar
    Department of Neurology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Annu Rev Neurosci 30:475-503. 2007
    ....
  4. pmc Mapping genetic influences on cortical regionalization
    Bradley L Schlaggar
    Departments of Neurology, Radiology, Pediatrics, and Anatomy and Neurobiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuron 72:499-501. 2011
    ..Their results resonate with findings from animal studies and certain human syndromes of developmental cortical malformation...
  5. ncbi request reprint Developmental changes in human cerebral functional organization for word generation
    Timothy T Brown
    Department of Psychology, Washington University in St Louis, St Louis, MO 63130, USA
    Cereb Cortex 15:275-90. 2005
    ..The hemodynamic magnitude, neuroanatomical location and maturational timecourse of these progressive and regressive changes have implications for models of the developing specialization in human cerebral functional organization...
  6. ncbi request reprint Comparison of functional activation foci in children and adults using a common stereotactic space
    Hyunseon Christine Kang
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuroimage 19:16-28. 2003
    ..The small differences in time courses and locations of activation foci between child and adult brains validate the feasibility of direct statistical comparison of these groups within a common space...
  7. ncbi request reprint A comparison of analysis of variance and correlation methods for investigating cognitive development with functional magnetic resonance imaging
    Damien A Fair
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Dev Neuropsychol 30:531-46. 2006
    ..These findings suggest that full characterization of developmental dynamics will require converging methodologies...
  8. ncbi request reprint Comparison of sustained and transient activity in children and adults using a mixed blocked/event-related fMRI design
    Kristin K Wenger
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuroimage 22:975-85. 2004
    ....
  9. pmc Defining functional areas in individual human brains using resting functional connectivity MRI
    Alexander L Cohen
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuroimage 41:45-57. 2008
    ..Our approach reliably produces maps of bounded regions appropriate in size and number for putative functional areas. These findings will hopefully stimulate further methodological refinements and validations...
  10. pmc Control networks in paediatric Tourette syndrome show immature and anomalous patterns of functional connectivity
    Jessica A Church
    Department of Neurology, Washington University School of Medicine, St Louis, MS 63110, USA
    Brain 132:225-38. 2009
    ..These results suggest that in adolescents with TS, immature functional connectivity is widespread, with additional, more profound deviation of connectivity in regions related to adaptive online control...
  11. pmc Lack of generalizability of sex differences in the fMRI BOLD activity associated with language processing in adults
    S K Z Ihnen
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuroimage 45:1020-32. 2009
    ..In particular, generalization or replication of a result in independent data sets is necessary for establishing conclusive support for any hypothesis about differences in brain function between groups...
  12. doi request reprint Mapping the human brain at rest with diffuse optical tomography
    Brian R White
    Department of Physics, Washington University, St Louis, MO, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:4070-2. 2009
    ....
  13. pmc Role of the anterior insula in task-level control and focal attention
    Steven M Nelson
    Department of Neurology, School of Medicine, Washington University, 4525 Scott Ave, Saint Louis, MO 63110, USA
    Brain Struct Funct 214:669-80. 2010
    ..These findings suggest that there exists some functional heterogeneity within aI that may subserve related but distinct types of higher-order cognitive processing...
  14. pmc A parcellation scheme for human left lateral parietal cortex
    Steven M Nelson
    Department of Neurology, Washington University, St Louis, MO 63110, USA
    Neuron 67:156-70. 2010
    ..This parcellation should serve as a roadmap for future investigations aimed at understanding LLPC function...
  15. pmc The development of human functional brain networks
    Jonathan D Power
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuron 67:735-48. 2010
    ....
  16. pmc Prediction of individual brain maturity using fMRI
    Nico U F Dosenbach
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Science 329:1358-61. 2010
    ..The greatest relative contribution to predicting individual brain maturity was made by the weakening of short-range functional connections between the adult brain's major functional networks...
  17. doi request reprint Development of the brain's functional network architecture
    Alecia C Vogel
    Department of Neurology, Washington University School of Medicine, St Louis, MO, USA
    Neuropsychol Rev 20:362-75. 2010
    ..Second, this developmental change in functional connectivity occurs, in general, via mechanisms of segregation of local regions and integration of distant regions into disparate subnetworks...
  18. ncbi request reprint The feasibility of a common stereotactic space for children and adults in fMRI studies of development
    E Darcy Burgund
    Department of Neurology, Neurobiology, Howard Hughes Medical Institute, Washington University, St Louis, Missouri 63110, USA
    Neuroimage 17:184-200. 2002
    ....
  19. pmc A developmental fMRI study of reading and repetition reveals changes in phonological and visual mechanisms over age
    Jessica A Church
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Cereb Cortex 18:2054-65. 2008
    ..These results are consistent with decreasing reliance on phonological processing, and increasing tuning of visual mechanisms, with age...
  20. pmc A dual-networks architecture of top-down control
    Nico U F Dosenbach
    Washington University in St Louis School of Medicine, 4525 Scott Ave, St Louis, MO 63110, USA
    Trends Cogn Sci 12:99-105. 2008
    ..The control systems of the brain seem to embody the principles of complex systems, encouraging resilient performance...
  21. pmc Development of distinct control networks through segregation and integration
    Damien A Fair
    Departments of Neurology, Washington University, St Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 104:13507-12. 2007
    ..Delay/disruption in the developmental processes of segregation and integration may play a role in disorders of control, such as autism, attention deficit hyperactivity disorder, and Tourette's syndrome...
  22. pmc A core system for the implementation of task sets
    Nico U F Dosenbach
    Department of Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Neuron 50:799-812. 2006
    ..Prefrontal regions commonly related to task control carried task-set signals in a smaller subset of tasks and lacked convergence across signal types...
  23. pmc Distinct brain networks for adaptive and stable task control in humans
    Nico U F Dosenbach
    Department of Radiology, Washington University, St Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 104:11073-8. 2007
    ..These two independent networks appear to operate on different time scales and affect downstream processing via dissociable mechanisms...
  24. pmc A method for using blocked and event-related fMRI data to study "resting state" functional connectivity
    Damien A Fair
    Department of Neurology, Washington University School of Medicine, Campus Box 8111, 660 S Euclid, St Louis, MO 63110, USA
    Neuroimage 35:396-405. 2007
    ..Although using event-related data residuals for resting state functional connectivity may still be useful, results should be interpreted with care...
  25. ncbi request reprint fMRI reveals novel functional neuroanatomy in a child with perinatal stroke
    Damien A Fair
    PA C, Department of Neurology, Campus Box 8111, Washington University School of Medicine, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Neurology 67:2246-9. 2006
    ..Although the data for this child are similar to the control group, there are age-dependent differences...
  26. doi request reprint Functional neuroanatomy of lexical processing in children with cleft lip and palate
    Devra B Becker
    Division of Plastic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, MO, USA
    Plast Reconstr Surg 122:1371-82. 2008
    ..Emerging evidence indicates that children with cleft lip and/or cleft palate have higher rates of learning disabilities than the general population and differences in brain morphology...
  27. pmc Resting-state functional connectivity in the human brain revealed with diffuse optical tomography
    Brian R White
    Department of Radiology, Washington University, St Louis, MO 63110, USA
    Neuroimage 47:148-56. 2009
    ..In addition, the comprehensive hemoglobin contrasts of fc-DOT enable innovative studies of the biophysical origin of the functional connectivity signal...
  28. pmc The "Task B problem" and other considerations in developmental functional neuroimaging
    Jessica A Church
    Department of Neurology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Hum Brain Mapp 31:852-62. 2010
    ....
  29. pmc Retinotopic mapping of adult human visual cortex with high-density diffuse optical tomography
    Benjamin W Zeff
    Department of Radiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 104:12169-74. 2007
    ..These results demonstrate that high-density DOT is a practical and powerful tool for mapping function in the human cortex...
  30. pmc The maturing architecture of the brain's default network
    Damien A Fair
    Department of Neurology, Washington University, St Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 105:4028-32. 2008
    ..We found that the default regions are only sparsely functionally connected at early school age (7-9 years old); over development, these regions integrate into a cohesive, interconnected network...
  31. ncbi request reprint Development of letter-specific processing: the effect of reading ability
    E Darcy Burgund
    Department of Psychology MS 25, Rice University, P O Box 1892, Houston, TX 77251, USA
    Acta Psychol (Amst) 122:99-108. 2006
    ..Findings support theories of perceptual expertise, which suggest that skilled processing drives the specialization of perceptual mechanisms for certain classes of stimuli...
  32. ncbi request reprint The development of sustained and transient neural activity
    E Darcy Burgund
    Department of Psychology, MS 25, Rice University, PO Box 1892, Houston, TX 77251, USA
    Neuroimage 29:812-21. 2006
    ..Moreover, these results underscore the value of separating sustained and transient signals in fMRI studies of development...
  33. ncbi request reprint Does human functional brain organization shift from diffuse to focal with development?
    Timothy T Brown
    Department of Psychology, Washington University in St Louis, USA
    Dev Sci 9:9-11. 2006
  34. ncbi request reprint Task demands modulate sustained and transient neural activity during visual-matching tasks
    E Darcy Burgund
    Department of Psychology, MS 25, Rice University, PO Box 1892, Houston, TX 77251, USA
    Neuroimage 25:511-9. 2005
    ..In combination, results suggest that sustained and transient activities interact to produce the context-appropriate response during visual-matching tasks...

Research Grants6

  1. Development of Orthographic Knowledge: fMRI Studies
    Bradley Schlaggar; Fiscal Year: 2007
    ....
  2. DEVELOPMENT OF SKILLED READING: FMRI STUDIES
    Bradley L Schlaggar; Fiscal Year: 2010
    ....
  3. DEVELOPMENT OF SKILLED READING: FMRI STUDIES
    Bradley L Schlaggar; Fiscal Year: 2010
    ....