- Polyamine transport by the polyspecific organic cation transporters OCT1, OCT2, and OCT3Monica Sala-Rabanal
Department of Cell Biology and Physiology, and Center for Investigation of Membrane Excitability Diseases, Washington University School of Medicine, St Louis, Missouri 63110, USA
Mol Pharm 10:1450-8. 2013..The identification of OCTs as polyamine transport systems may contribute to further understanding of the mechanisms involved in polyamine homeostasis and aid in the design of polyamine-like OCT-targeted drugs...
- Molecular mechanisms of EAST/SeSAME syndrome mutations in Kir4.1 (KCNJ10)Monica Sala-Rabanal
Department of Cell Biology and Physiology, Washington University, St Louis, Missouri 63110, USA
J Biol Chem 285:36040-8. 2010..These results provide an explanation for the molecular defects that underlie the EAST/SeSAME syndrome...
- Self-cleavage of human CLCA1 protein by a novel internal metalloprotease domain controls calcium-activated chloride channel activationZeynep Yurtsever
Biochemistry Program, Washington University School of Medicine, St Louis, Missouri 63110, USA
J Biol Chem 287:42138-49. 2012..These data provide both a mechanistic basis for CLCA1 self-cleavage and a novel mechanism for regulation of chloride channel activity specific to the mucosal interface...