Research Topics
Species | Eric J RichardsSummaryAffiliation: Washington University School of Medicine Country: USA Publications
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Detail Information
Publications
Gene duplication and hypermutation of the pathogen Resistance gene SNC1 in the Arabidopsis bal variantHankuil Yi
Department of Biology, Washington University, St Louis, Missouri 63130, USA
Genetics 183:1227-34. 2009..We propose that the high degree of variation in SNC1-related sequences among Arabidopsis natural accessions follows the two-step mechanism observed in the bal variant: gene duplication followed by hypermutation...
Inherited epigenetic variation--revisiting soft inheritanceEric J Richards
Department of Biology, Washington University, 1 Brookings Drive, St Louis, Missouri 63130, USA
Nat Rev Genet 7:395-401. 2006..Should the existence of inherited epigenetic variation alter our thinking about evolutionary change?..- Natural variation in DNA methylation in ribosomal RNA genes of Arabidopsis thalianaHye Ryun Woo
Department of Biology, Washington University, One Brookings Drive, St Louis, MO 63130, USA
BMC Plant Biol 8:92. 2008..An epigenetic switch, mediated by DNA methylation and histone modification, turns rRNA genes on and off. However, little is known about the mechanisms that specify and maintain the patterns of NOR DNA methylation... - Three SRA-domain methylcytosine-binding proteins cooperate to maintain global CpG methylation and epigenetic silencing in ArabidopsisHye Ryun Woo
Department of Biology, Washington University in St Louis, St Louis, Missouri, United States of America
PLoS Genet 4:e1000156. 2008..Our findings demonstrate that VIM1, VIM2, and VIM3 have overlapping functions in maintenance of global CpG methylation and epigenetic transcriptional silencing... - A cluster of disease resistance genes in Arabidopsis is coordinately regulated by transcriptional activation and RNA silencingHankuil Yi
Department of Biology, Washington University, St Louis, MO 63130, USA
Plant Cell 19:2929-39. 2007..These data indicate many Columbia RPP5 locus R genes can be coordinately regulated both positively and negatively and suggest that the RPP5 locus is poised to respond to pathogens that disturb RNA silencing... - VIM1, a methylcytosine-binding protein required for centromeric heterochromatinizationHye Ryun Woo
Department of Biology, Washington University, St Louis, Missouri 63130, USA
Genes Dev 21:267-77. 2007..VIM1 associates with methylated genomic loci in vivo and is enriched in chromocenters. Our findings suggest that VIM1 acts at the DNA methylation-histone interface to maintain centromeric heterochromatin... - Differential epigenetic regulation within an Arabidopsis retroposon familySanjida H Rangwala
Department of Biology, Washington University, St Louis, Missouri 63130, USA
Genetics 176:151-60. 2007..We discuss the different modes of regulation within this family and the potential impact of this regulation on the stability of silencing in natural populations... - Meiotically stable natural epialleles of Sadhu, a novel Arabidopsis retroposonSanjida H Rangwala
Department of Biology, Washington University in St. Louis, St. Louis, Missouri, USA
PLoS Genet 2:e36. 2006..These findings support the view that an important component of natural variation in retroelements is epigenetic... - Arabidopsis MET1 cytosine methyltransferase mutantsMark W Kankel
Department of Biology, Washington University, St Louis, Missouri 63130, USA
Genetics 163:1109-22. 2003..ddm1 met1 double mutants were constructed to further our understanding of the mechanism of DDM1 action and the interaction between two major genetic loci affecting global cytosine methylation levels in Arabidopsis... - Signaling silence--breaking ground and spreading outHye Ryun Woo
Department of Biology, Washington University in St Louis, St Louis, Missouri 63130, USA
Genes Dev 22:1719-23. 2008.... - Genetic variation in epigenetic inheritance of ribosomal RNA gene methylation in ArabidopsisNicole C Riddle
Department of Biology, Washington University, One Brookings Drive, St Louis, MO 63130, USA
Plant J 41:524-32. 2005..Our results indicate that the inheritance of differential cytosine methylation states at NOR loci can be modified by their genetic context, opening up the possibility of genetic dissection of epigenetic inheritance... - Induced instability of two Arabidopsis constitutive pathogen-response allelesTrevor L Stokes
Department of Biology, Washington University, One Brookings Drive, St. Louis, MO 63130, USA
Proc Natl Acad Sci U S A 99:7792-6. 2002..The cpr1-1 allele is the third candidate epigenetic allele originating from this R-like gene cluster, making the region a possible hotspot of epigenetic variation... 
Population epigeneticsEric J Richards
Department of Biology, Washington University, One Brookings Drive, St Louis, MO 63130, USA
Curr Opin Genet Dev 18:221-6. 2008..Population epigenetics, emerging as an active subfield at the interface of molecular genetics, genomics, and population biology, addresses questions concerning the prevalence and importance of epigenetic variation in the natural world...- LITTLE NUCLEI genes affecting nuclear morphology in Arabidopsis thalianaTravis A Dittmer
Department of Biology, Washington University, St Louis, MO 63130, USA
Plant Cell 19:2793-803. 2007..Rather, the density of DNA packaging at all endopolyploid levels in the linc1 linc2 mutants was increased significantly. Our results indicate that the LINC coiled-coil proteins are important determinants of plant nuclear structure... - The value-added genome: building and maintaining genomic cytosine methylation landscapesSanjida H Rangwala
Department of Biology, Campus Box 1137, One Brookings Drive, Washington University, St Louis, MO 63108, USA
Curr Opin Genet Dev 14:686-91. 2004..While genetics continues to more fully define these mechanisms, genomic studies in Arabidopsis have yielded an unprecedented high-resolution view of how epigenetic marks are layered over a genome... - The control of natural variation in cytosine methylation in ArabidopsisNicole C Riddle
Department of Biology, Washington University, Saint Louis, Missouri 63130, USA
Genetics 162:355-63. 2002..Our results also suggest that divergence and inheritance of epigenetic information, independent of changes in underlying nucleotide sequence, may play an important role in maintaining natural variation in cytosine methylation... - Chromatin methylation: who's on first?Eric J Richards
Department of Biology, Washington University, St Louis, MO 63108, USA
Curr Biol 12:R694-5. 2002.... - Epigenetic variation in Arabidopsis disease resistanceTrevor L Stokes
Department of Biology, Washington University, St. Louis, Missouri 63130, USA
Genes Dev 16:171-82. 2002..Overexpression of a related R-like gene also occurs in the ssi1 (suppressor of SA insensitivity 1) background, suggesting that ssi1 is mechanistically related to bal... - Phenotypic instability of Arabidopsis alleles affecting a disease Resistance gene clusterHankuil Yi
Department of Biology, Washington University, One Brookings Drive, St, Louis, MO 63130, USA
BMC Plant Biol 8:36. 2008.... - Epigenetic codes for heterochromatin formation and silencing: rounding up the usual suspectsEric J Richards
Department of Biology, Washington University, One Brookings Drive, St. Louis, MO 63130, USA
Cell 108:489-500. 2002..All three modifications used in packaging heterochromatin are also used in stable silencing of euchromatic genes... - Natural variation in a subtelomeric region of Arabidopsis: implications for the genomic dynamics of a chromosome endHui-Fen Kuo
Department of Biology, Washington University, St. Louis, Missouri 63130, USA
Genetics 173:401-17. 2006..This natural variation study highlights the variety of genomic events that drive the fluidity of chromosome termini... - Genetic and epigenetic dissection of cis regulatory variationXu Zhang
Department of Ecology and Evolution, The University of Chicago, Chicago, Illinois 60637, USA
Curr Opin Plant Biol 10:142-8. 2007.... - Analysis of histone acetyltransferase and histone deacetylase families of Arabidopsis thaliana suggests functional diversification of chromatin modification among multicellular eukaryotesRitu Pandey
Department of Plant Sciences, University of Arizona, Tucson, AZ 85721-0036, USA
Nucleic Acids Res 30:5036-55. 2002....