Research Topics
Genomes and Genes | Janet S RaderSummaryAffiliation: Washington University School of Medicine Country: USA Publications
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Detail Information
Publications
MLH3 mutation in endometrial cancerNicholas P Taylor
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Washington University School of Medicine, 4911 Barnes Jewish Hospital Plaza, St Louis, MO 63110, USA
Cancer Res 66:7502-8. 2006..The identification of inherited missense variants, somatic missense mutations (present in 3 of 57 tumors), and LOH in the tumor from a patient with a germ line missense change suggest a role for MLH3 in endometrial tumorigenesis...
A unified sample preparation protocol for proteomic and genomic profiling of cervical swabs to identify biomarkers for cervical cancer screeningJanet S Rader
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine and Alvin J Siteman Cancer Center, St Louis, MO, USA Department of Genetics, Washington University School of Medicine and Alvin J Siteman Cancer Center, St Louis, MO, USA
Proteomics Clin Appl 2:1658-69. 2008..HNRPA2B1 was identified as a biomarker candidate with increased expression in cancer compared to normal cervix and validated by Western blot...
Phase I study and preliminary pharmacology of the novel innate immune modulator rBBX-01 in gynecologic cancersJanet S Rader
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, Missouri 63110, USA
Clin Cancer Res 14:3089-97. 2008..This phase I trial was done to determine the safety and basic pharmacology of rBBX-01...- CD83 gene polymorphisms increase susceptibility to human invasive cervical cancerZhengyan Zhang
Department of Obstetrics and Gynecology, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8064, St Louis, MO 63110, USA
Cancer Res 67:11202-8. 2007..None of seven nearby genes was differentially expressed in cervical cancer. The importance of CD83 in epithelial versus dendritic cells needs to be determined, as does its role in promoting cervical cancer... - Lymph node staging by positron emission tomography in cervical cancer: relationship to prognosisElizabeth A Kidd
Department of Radiation Oncology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, 4921 Parkview Place, Box 8224, St Louis, MO 63110, USA
J Clin Oncol 28:2108-13. 2010..27 (95% CI 16.56 to 55.34). CONCLUSION Nodal involvement detected by FDG-PET in cervical cancer relates to clinical stage, is comparable to historical data, and stratifies patient recurrence and survival outcomes... - Preoperative lymph node staging of early-stage cervical carcinoma by [18F]-fluoro-2-deoxy-D-glucose-positron emission tomographyJason D Wright
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine and Alvin J Siteman Cancer Center, St Louis, Missouri 63110, USA
Cancer 104:2484-91. 2005..The objective of this study was to determine the sensitivity and specificity of PET in detecting lymph node metastasis in women with early-stage cervical carcinoma... - DNA mismatch repair and TP53 defects are early events in uterine carcinosarcoma tumorigenesisNicholas P Taylor
Division of Gynecologic Oncology, Washington University School of Medicine and Siteman Cancer Center, St Louis, MO 63110, USA
Mod Pathol 19:1333-8. 2006..The high rate of concordance for these molecular defects between the carcinoma and sarcoma components adds to existing molecular evidence that carcinosarcomas are clonal malignancies... - Bevacizumab combination therapy in recurrent, platinum-refractory, epithelial ovarian carcinoma: A retrospective analysisJason D Wright
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, Missouri 63110, USA
Cancer 107:83-9. 2006..The study was undertaken to determine the safety and efficacy of the monoclonal, antivascular endothelial growth factor antibody bevacizumab in combination with cytotoxic chemotherapy for women with platinum-refractory ovarian cancer... - Microsatellite instability and epigenetic inactivation of MLH1 and outcome of patients with endometrial carcinomas of the endometrioid typeIsrael Zighelboim
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO 63110, USA
J Clin Oncol 25:2042-8. 2007..We sought to determine whether MSI and MLH1 methylation are associated with clinicopathologic variables and survival outcomes in a large series of patients with endometrial carcinomas of the endometrioid type... - Human papillomavirus triage for young women with atypical squamous cells of undetermined significanceJason D Wright
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, Missouri 63110, USA
Obstet Gynecol 107:822-9. 2006..We sought to estimate the usefulness of human papillomavirus testing for young women with atypical squamous cells of undetermined significance... - Cervical dysplasia in adolescentsJason D Wright
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, Missouri 63110, USA
Obstet Gynecol 106:115-20. 2005..We determined the natural history and outcome of adolescents with low-grade squamous intraepithelial lesions (LSIL) and high-grade squamous intraepithelial lesions (HSIL)... - Phase II evaluation of topotecan and navelbine in patients with recurrent ovarian, fallopian tube or primary peritoneal cancerThomas J Herzog
Division of Gynecologic Oncology, Columbia University, College of Physicians and Surgeons, Irving Cancer Center, New York, NY 10032, USA
Gynecol Oncol 111:467-73. 2008..To assess the efficacy and toxicity profile in patients with recurrent ovarian or primary peritoneal cancer treated with topotecan at 2.5 mg/m(2) days 1 and 8 plus vinorelbine at 25 mg/m(2) days 1 and 8 every 3 weeks... - Surveillance FDG-PET detection of asymptomatic recurrences in patients with cervical cancerRebecca A Brooks
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
Gynecol Oncol 112:104-9. 2009..To evaluate survival after detection of recurrent cervical cancer by FDG-PET in symptomatic versus asymptomatic patients... - "Surgical Apgar Score" predicts postoperative complications after cytoreduction for advanced ovarian cancerIsrael Zighelboim
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine and Siteman Cancer Center, 4911 Barnes Jewish Hospital Plaza, St Louis, MO 63110, USA
Gynecol Oncol 116:370-3. 2010..We sought to estimate the ability of this metric to predict major postoperative complications in women undergoing ovarian cancer cytoreductive procedures... - Clinical outcomes of definitive intensity-modulated radiation therapy with fluorodeoxyglucose-positron emission tomography simulation in patients with locally advanced cervical cancerElizabeth A Kidd
Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
Int J Radiat Oncol Biol Phys 77:1085-91. 2010..This study aimed to evaluate the toxicity and clinical outcomes for cervical cancer patients treated definitively with intensity-modulated radiation therapy (IMRT) compared with non-IMRT treatment... - Prospective evaluation of FDG-PET for detecting pelvic and para-aortic lymph node metastasis in uterine corpus cancerNeil S Horowitz
Division of Gynecologic Oncology, Departments of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO 63110, USA
Gynecol Oncol 95:546-51. 2004.... - Chemoradiation in locally advanced cervical carcinoma: an analysis of cisplatin dosing and other clinical prognostic factorsElizabeth K Nugent
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, 4911 Barnes Jewish Hospital Plaza, 4th Floor Maternity, St Louis, MO 63110, USA
Gynecol Oncol 116:438-41. 2010..The aim of this study was to evaluate the effect of number of chemotherapy cycles and other clinical and pathologic factors on progression-free (PFS) and overall survival (OS) in patients with newly diagnosed cervical cancer... - Human papillomavirus type and tobacco use as predictors of survival in early stage cervical carcinomaJason D Wright
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, 4911 Barnes Hospital Plaza, Box 8064, St Louis, MO 63110, USA
Gynecol Oncol 98:84-91. 2005..The aim of this study was to define the prognostic significance of HPV 18 and its phylogenetically related viruses and smoking on survival in patients with early stage cervical cancer... - Utility of parametrectomy for early stage cervical cancer treated with radical hysterectomyJason D Wright
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
Cancer 110:1281-6. 2007..Parametrectomy results in significant morbidity. The objective of the study was to determine factors predictive of parametrial tumor spread and to define a subset of patients at low risk for parametrial disease... - FDG-PET evaluation of vaginal carcinomaWayne T Lamoreaux
Department of Radiation Oncology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA
Int J Radiat Oncol Biol Phys 62:733-7. 2005..The 3-year progression-free and overall survival estimate was 73% and 68%, respectively. CONCLUSION: The results of this study have demonstrated that FDG-PET detects the primary tumor and abnormal lymph nodes more often than does CT... - TP53, MDM2, NQO1, and susceptibility to cervical cancerXiaoxia Hu
Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, Missouri, USA
Cancer Epidemiol Biomarkers Prev 19:755-61. 2010..Our results indicate that functional polymorphisms in TP53 codon 72 and NQO1 SNP609 associate with the risk of cervical cancer especially in women infected with type 16- and/or type 18-related HPVs... - CA-125 response in patients with recurrent ovarian or primary peritoneal cancer treated with pegylated liposomal doxorubicin or topotecanGabrielle Gossner
Washington University School of Medicine, St. Louis, MO 63110, USA
Gynecol Oncol 103:212-8. 2006..An initial increase in CA-125 should not mandate discontinuation of current therapy, but a successive rise over two or more cycles reliably predicts that a treatment response ultimately is unlikely... - Fine mapping and evaluation of candidate genes for cervical cancer on 11q23Zhengyan Zhang
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Washington University School of Medicine, St. Louis, Missouri 63110, USA
Genes Chromosomes Cancer 43:95-103. 2005..6-Mb stretch of DNA on 11q23.3-q24.1 and that somatic mutations in RNF26, USP2, TRIM29, POU2F3, or PPP2R1B probably are not important for cervical carcinogenesis... - Comparison of high-dose-rate and low-dose-rate brachytherapy in the treatment of endometrial carcinomaAlaa Fayed
Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
Int J Radiat Oncol Biol Phys 67:480-4. 2007..To compare the outcomes for endometrial carcinoma patients treated with either high-dose-rate (HDR) or low-dose-rate (LDR) brachytherapy... - Body mass index: relationship to clinical, pathologic and features of microsatellite instability in endometrial cancerCarolyn K McCourt
Department of Obstetrics and Gynecology, Washington University School of Medicine, Saint Louis, MO, USA
Gynecol Oncol 104:535-9. 2007.... - ATR mutation in endometrioid endometrial cancer is associated with poor clinical outcomesIsrael Zighelboim
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, 4911 Barnes Jewish Plaza, Box 8064, St Louis, MO 63110, USA
J Clin Oncol 27:3091-6. 2009..Knowledge of ATR mutation status may hold promise for individualized treatment and targeted therapies in patients with endometrial cancer... - Penetrance and expressivity of MSH6 germline mutations in seven kindreds not ascertained by family historyBarbara M Buttin
Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO 63110, USA
Am J Hum Genet 74:1262-9. 2004..A combination of MSI and immunohistochemistry analyses may be helpful in screening for MSH6 mutation carriers... - Cervical carcinoma in the elderly: an analysis of patterns of care and outcomeJason D Wright
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, Missouri 63110, USA
Cancer 103:85-91. 2005..Advanced age often is considered a poor prognostic factor for cervical carcinoma. The authors investigated the patterns of care and treatment outcomes of elderly women with cervical carcinoma... - A microRNA expression signature for cervical cancer prognosisXiaoxia Hu
Departments of Radiation Oncology, Pathology and Immunology, and Obstetrics and Gynecology, Washington University School of Medicine, St Louis, Missouri 63110, USA
Cancer Res 70:1441-8. 2010..In particular, miR-200a is likely to affect the metastatic potential of cervical cancer cells by coordinate suppression of multiple genes controlling cell motility... - Effect of a T0 radical hysterectomy specimen on survival for early stage cervical cancerJason D Wright
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, 161 Fort Washington Ave, 8th Floor, New York, NY 10032, USA
Gynecol Oncol 107:280-4. 2007..The goal of this study was to evaluate the outcome of patients with no residual tumor (T0) in their hysterectomy specimens... - External radiotherapy versus vaginal brachytherapy for patients with intermediate risk endometrial cancerLilie L Lin
Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
Gynecol Oncol 106:215-20. 2007..To determine if brachytherapy alone is adequate adjuvant local therapy in patients classified as intermediate risk after complete surgical staging for endometrioid adenocarcinoma... - Outcomes in 24 selected patients with stage IVB cervical cancer and excellent performance status treated with radiotherapy and chemotherapyIsrael Zighelboim
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Washington University School of Medicine, Alvin J Siteman Cancer Center, St Louis, MO, USA
Radiat Med 24:625-30. 2006..We sought to review outcomes in patients with stage IVB carcinoma of the cervix treated with irradiation in combination with chemotherapy... - The effects of body mass index on complications and survival outcomes in patients with cervical carcinoma undergoing curative chemoradiation therapyNora T Kizer
Division of Gynecologic Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA
Cancer 117:948-56. 2011..The effect of body mass index (BMI) on treatment outcomes for patients with locally advanced cervical carcinoma who receive definitive chemoradiation is unclear... - Differential display identifies overexpression of the USP36 gene, encoding a deubiquitinating enzyme, in ovarian cancerJianduan Li
Department of Obstetrics, Gynecology, Division of Gynecologic Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
Int J Med Sci 5:133-42. 2008..To find potential diagnostic markers or therapeutic targets, we used differential display technique to identify genes that are over or under expressed in human ovarian cancer... - Acute toxicity of postoperative IMRT and chemotherapy for endometrial cancerRyan M Tierney
Department of Radiation Oncology, Box 8224, Mallinckrodt Institute of Radiology, Washington University School of Medicine, 4921 Parkview Place, Lower Level, St Louis, MO 63110, USA
Radiat Med 25:439-45. 2007..The aim of this study was to determine the acute toxicity of postoperative intensity-modulated radiotherapy (IMRT) with and without chemotherapy in patients with endometrial cancer... - Identification of chromosomal alterations important in the development of cervical intraepithelial neoplasia and invasive carcinoma using alignment of DNA microarray dataMargaret A Fitzpatrick
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
Gynecol Oncol 103:458-62. 2006..CONCLUSIONS: Alignment of microarray expression data by chromosomes can be used to estimate regions of potential chromosomal aberration and identify differentially expressed genes important in the development of CIN and invasive cancer... - Relationship of ovarian neoplasms and body mass indexJason D Wright
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO 63110, USA
J Reprod Med 50:595-602. 2005..To describe the distribution of benign and malignant ovarian neoplasms among overweight and obese women... - Liquid-based cytology for the postirradiation surveillance of women with gynecologic malignanciesJason D Wright
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO 63110, USA
Gynecol Oncol 91:134-8. 2003..CONCLUSIONS: ThinPrep for the surveillance of women with gynecologic malignancies treated with radiotherapy is associated with a high rate of satisfactory samples and a low rate of equivocal and ASCUS cytology... - Panniculectomy: improving lymph node yield in morbidly obese patients with endometrial neoplasmsJason D Wright
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO 63110, USA
Gynecol Oncol 94:436-41. 2004..The goal of this study was to determine the effect of panniculectomy on staging adequacy and lymph node yield in obese women with endometrial carcinoma undergoing staging laparotomy... - Phase II evaluation of a 3-day infusion of topotecan in patients with recurrent ovarian or primary peritoneal cancerThomas J Herzog
Division of Gynecologic Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
Gynecol Oncol 103:637-41. 2006..To assess the efficacy and toxicity profile in patients treated with topotecan at 2.0 mg/m2/day x 3 days every 3 weeks... - Increased risk for hereditary nonpolyposis colorectal cancer-associated synchronous and metachronous malignancies in patients with microsatellite instability-positive endometrial carcinoma lacking MLH1 promoter methylationBarbara M Buttin
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Washington University School of Medicine, St. Louis, Missouri 63110, USA
Clin Cancer Res 10:481-90. 2004..These patients and their families may warrant more intense cancer surveillance... - IGSF4 promoter methylation and expression silencing in human cervical cancerJianduan Li
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO 63110, USA
Gynecol Oncol 96:150-8. 2005..We evaluated IGSF4, a putative TSG located in the region, for promoter methylation and gene silencing in CC cell lines and cervical tissues... - Cervical cancer histology and tumor differentiation affect 18F-fluorodeoxyglucose uptakeElizabeth A Kidd
Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA
Cancer 115:3548-54. 2009..This study aimed to evaluate the variation in cervical cancer glucose metabolism for different tumor histologies and levels of differentiation, as measured by the uptake of 18F-fluorodeoxyglucose (FDG) by positron emission tomography (PET)... - Phase I study of docetaxel in combination with the P-glycoprotein inhibitor, zosuquidar, in resistant malignanciesPaula M Fracasso
Department of Medicine, Alvin J Siteman Cancer Center, Washington University School of Medicine, St Louis, Missouri 63110, USA
Clin Cancer Res 10:7220-8. 2004..To determine the maximum tolerated dose, dose-limiting toxicity, and pharmacokinetics of docetaxel infused over 1 hour when given in combination with oral zosuquidar to patients with resistant solid tumors... - Denaturing high-performance liquid chromatography for detecting and typing genital human papillomavirusJianduan Li
Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri 63110, USA
J Clin Microbiol 41:5563-71. 2003..6% of the samples. Our results indicate that HPV typing by GP-dHPLC permits discrimination of common genital HPV types, detection of multiple HPV infections, and identification of HPV variants in clinical samples... - The value of perioperative imaging in patients with uterine sarcomasElizabeth K Nugent
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine and Siteman Cancer Center, USA
Gynecol Oncol 115:37-40. 2009..To explore the yield and impact of perioperative imaging on management among patients undergoing surgical resection and treatment of uterine sarcomas... - Polymorphisms in MMP9 and SIPA1 are associated with increased risk of nodal metastases in early-stage cervical cancerRebecca Brooks
Washington University School of Medicine Barnes Jewish Hospital, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, 4911 Barnes Jewish Hospital Plaza Box 8064, Saint Louis, MO 63110, USA
Gynecol Oncol 116:539-43. 2010..We investigated the association of these SNPs with nodal metastases in early-stage cervical cancer... - Bevacizumab combination therapy in heavily pretreated, recurrent cervical cancerJason D Wright
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO 63110, USA
Gynecol Oncol 103:489-93. 2006..To report the utility of the monoclonal, anti-vascular endothelial growth factor antibody bevacizumab in combination with cytotoxic chemotherapy for women with recurrent cervical cancer... - Bevacizumab therapy in patients with recurrent uterine neoplasmsJason D Wright
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Anticancer Res 27:3525-8. 2007..Angiogenesis plays an important role in endometrial carcinogenesis. We reviewed our experience with the anti-VEGF monoclonal antibody bevacizumab for the treatment of recurrent uterine neoplasms... - Epithelial ovarian tumors of low malignant potential: the role of microinvasionBarbara M Buttin
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri, USA
Obstet Gynecol 99:11-7. 2002..CA 125 monitoring may have a role in early detection of recurrence in patients with aggressive disease... - Prevalence of defective DNA mismatch repair and MSH6 mutation in an unselected series of endometrial cancersPaul J Goodfellow
Department of Surgery, Washington University School of Medicine, Campus Box 8109, 660 South Euclid Avenue, St Louis, MO 63110, USA
Proc Natl Acad Sci U S A 100:5908-13. 2003..The minimum estimate of the prevalence of inherited MSH6 mutation in endometrial cancer is 1.6% (7 of 441), comparable with the predicted prevalence for patients with colorectal cancer... - Long-term assessment of bladder and bowel dysfunction after radical hysterectomyRebecca A Brooks
Washington University School of Medicine Barnes Jewish Hospital, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, 4911 Barnes Jewish Hospital Plaza Box 8064, Saint Louis, MO 63110, USA
Gynecol Oncol 114:75-9. 2009..To determine the long-term effects of radical hysterectomy on bladder and bowel function... - Frequent HOXA11 and THBS2 promoter methylation, and a methylator phenotype in endometrial adenocarcinomaBradford P Whitcomb
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri 63110, USA
Clin Cancer Res 9:2277-87. 2003..HOXA11 promoter methylation was significantly more frequent in recurrent than nonrecurrent cases. HOXA11 methylation in early stage endometrial cancer is associated with poor outcome... - Long-term outcome of women who undergo panniculectomy at the time of gynecologic surgeryJason D Wright
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Washington University School of Medicine, 4911 Barnes Hospital Plaza, Box 8064, St Louis, MO 63110, USA
Gynecol Oncol 102:86-91. 2006..The goal of this study was to determine the long-term outcomes and patient satisfaction of women who underwent panniculectomy at the time of pelvic surgery... - Synchronous ovarian metastases at the time of laparotomy for colon cancerJason D Wright
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Washington University School of Medicine, St. Louis, MO 63110, USA
Gynecol Oncol 92:851-5. 2004..Surgical management should include extirpation of the primary tumor and any bulky ovarian metastases. Cytoreduction may be considered in highly selected patients... - Colposcopic accuracy of obstetrics and gynecology residentsMargaret E Baum
Division of General Gynecology, Department of Obstetrics and Gynecology, Washington University School of Medicine, Barnes Hospital Plaza, St. Louis, MO 63110, USA
Gynecol Oncol 103:966-70. 2006..7%). CONCLUSIONS: While the colposcopic impressions of gynecology residents were accurate, there was little difference in the accuracy of colposcopic assessment based upon the level of resident training... - Cervix carcinoma, concurrent chemoradiotherapy, and salvage of isolated paraaortic lymph node recurrenceAnurag K Singh
Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO 63110, USA
Int J Radiat Oncol Biol Phys 61:450-5. 2005..However, chemotherapy or radiotherapy alone produced dismal survival in patients with classic findings of recurrence... - The significance of pneumatosis intestinalis or bowel perforation in patients with gynecologic malignanciesNeil S Horowitz
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, Missouri 63110, USA
Gynecol Oncol 86:79-84. 2002..The objectives of this study were to evaluate the clinical significance and outcome of pneumatosis intestinalis or bowel perforation in patients with gynecologic malignancies... - Prospective evaluation of positron emission tomography for the detection of groin node metastases from vulvar cancerDavid E Cohn
Division of Gynecologic Oncology, Washington University School of Medicine, St Louis, Missouri, USA
Gynecol Oncol 85:179-84. 2002..We set out to determine the ability of positron emission tomography with fluorodeoxyglucose to detect groin lymph node metastases from vulvar cancer... - Resource utilization for ovarian cancer patients at the end of life: how much is too much?Sharyn N Lewin
Division of Gynecologic Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
Gynecol Oncol 99:261-6. 2005..The goal of this study was to compare the total cost of hospital-based resources utilized in ovarian cancer patients during their last 60 days of life for those enrolled in hospice versus those not on hospice... - Double cervix with bilateral and synchronous HSIL associated with different high-risk HPV types. A case reportKaren R Pinto
Department of Pathology and Immunology, Washington University Medical Center, 660 South Euclid Avenue, St. Louis, Missouri 63110, USA
Acta Cytol 48:273-7. 2004..The HPV types were different in the right and left cervices... - Cervical sarcomas: an analysis of incidence and outcomeJason D Wright
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, 4911 Barnes Hospital Plaza, Box 8064, St Louis, MO 63110, USA
Gynecol Oncol 99:348-51. 2005..Cervical sarcomas are exceedingly rare neoplasms associated with a poor prognosis. The objective of this study was to examine the treatment and outcome of women with cervical sarcomas... - Ribosomal DNA methylation in patients with endometrial carcinoma: an independent prognostic markerMatthew A Powell
Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, Missouri 63110, USA
Cancer 94:2941-52. 2002..The objective of this study was to investigate the prognostic significance of ribosomal DNA (rDNA) methylation in patients with endometrial carcinoma... - Primary peritoneal carcinoma presenting as adenocarcinoma on a Pap smear. A case reportJason D Wright
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, Missouri, USA
J Reprod Med 47:933-5. 2002..Primary peritoneal carcinoma is an uncommon malignancy that usually presents with gastrointestinal symptoms from abdominal carcinomatosis... - The accuracy of colposcopic grading for detection of high-grade cervical intraepithelial neoplasiaL Stewart Massad
Division of Gynecologic Oncology, Washington University School of Medicine, St Louis, MO 63110, USA
J Low Genit Tract Dis 13:137-44. 2009..To relate aspects of online colposcopic image assessment to the diagnosis of grades 2 and 3 cervical intraepithelial neoplasia (CIN 2+)... - Cardiac arrest during laparotomy with argon beam coagulation of metastatic ovarian cancerNora Kizer
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine and Siteman Comprehensive Cancer Center, St Louis, MO, USA
Int J Gynecol Cancer 19:237-8. 2009..The argon beam coagulation (ABC) is a safe and effective tool for surgical cytoreduction of metastatic ovarian carcinomas... - Phase I dose and sequencing study of pegylated liposomal doxorubicin and docetaxel in patients with advanced malignanciesPaula M Fracasso
Alvin J Siteman Cancer Center, St Louis, Missouri 63110, USA
Cancer 98:610-7. 2003..The authors conducted a Phase I trial to evaluate the maximum tolerated dose (MTD), toxicities, and effect of dose sequencing of this combination in patients with advanced malignancies... - Acute abdominal pain with a calcified pelvic massJason D Wright
Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, Missouri 63110, USA
J Pediatr Adolesc Gynecol 16:237-41. 2003..A case of a 15-year-old with a calcified pelvic mass is presented with a review of the differential diagnosis... - Phase II trial of pyrazoloacridine in patients with persistent or recurrent endometrial carcinoma: a Gynecologic Oncology Group StudySteven C Plaxe
Division of Gynecologic Oncology, University of California at San Diego, San Diego, California 92103, USA
Gynecol Oncol 84:241-4. 2002..CONCLUSION: This dose and schedule of PZA has insignificant activity in this population. The optimal PZA dose appears to vary between different populations and may be related to prior therapy... - Randomized trial of cisplatin and ifosfamide with or without bleomycin in squamous carcinoma of the cervix: a gynecologic oncology group studyJeffrey D Bloss
Division of Gynecologic Oncology, Ellis Fischel Cancer Center, University of Missouri Health Sciences Center, Columbia, USA
J Clin Oncol 20:1832-7. 2002..Thus, the addition of bleomycin in the dose-schedule employed to cisplatin and ifosfamide did not improve outcome in patients with advanced cervical cancer... - Expression and localization of GRP75 in human epithelial tumors and normal tissuesTomasz Srokowski
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Washington University School of Medicine, St. Louis, MO 63110, USA
Appl Immunohistochem Mol Morphol 12:132-8. 2004..The authors conclude that GRP75 is highly expressed in both benign and malignant epithelium, as well as cells of specialized function from a variety of tissues... - Evaluation of candidate methylation markers to detect cervical neoplasiaNarayan Shivapurkar
Hamon Center for Therapeutic Oncology Research, Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75930, USA
Gynecol Oncol 107:549-53. 2007..We used quantitative PCR assays to evaluate methylation in five candidate genes (TNFRSF10C, DAPK1, SOCS3, HS3ST2 and CDH1) previously demonstrated as methylated in cervical cancer... - Surgical-pathological predictors of disease-free survival and risk groupings for IB2 cervical cancer: do the traditional models still apply?Scott A Kamelle
Oklahoma Health Sciences Center, USA
Gynecol Oncol 94:249-55. 2004..To evaluate how the independent predictors of recurrence for stage IB2 cervical cancers treated with up-front radical hysterectomy apply to established risk models... - A comparison of stages IB1 and IB2 cervical cancers treated with radical hysterectomy. Is size the real difference?Teresa L Rutledge
University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
Gynecol Oncol 95:70-6. 2004..To compare stages IB1 and IB2 cervical cancers treated with radical hysterectomy (RH) and to define predictors of nodal status and recurrence... - Profiling microdissected epithelium and stroma to model genomic signatures for cervical carcinogenesis accommodating for covariatesDavid Gius
Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
Cancer Res 67:7113-23. 2007.... - Identification of novel methylation markers in cervical cancer using restriction landmark genomic scanningSophia S Wang
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852 7234, USA
Cancer Res 68:2489-97. 2008..Inclusion of NOL4 and LHFPL4 in evaluating methylation panels for early detection, risk prediction, and etiologic research on cervical cancer is warranted... - Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growthXiaohong Wang
HIV and AIDS Malignancy Branch, Center for Cancer Research, Nation Cancer Institute National Institutes of Health, Bethesda, Maryland, United States of America
PLoS ONE 3:e2557. 2008..When introduced into cell lines, miR-146a was found to promote cell proliferation. Collectively, our data indicate that downregulation of miR-143 and miR-145 and upregulation of miR-146a play a role in cervical carcinogenesis... - Cervical tissue collection methods for RNA preservation: comparison of snap-frozen, ethanol-fixed, and RNAlater-fixationSophia S Wang
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
Diagn Mol Pathol 15:144-8. 2006.... - Cervical cancer prevention in the era of prophylactic vaccines: a preview for gynecologic oncologistsYvonne Collins
University of Illinois, Chicago, IL, USA
Gynecol Oncol 102:552-62. 2006..Gynecologic oncologists will continue to play an important role in promoting optimal prevention practices...