Research Topics
| J A PosenerSummaryAffiliation: Washington University School of Medicine Country: USA Publications
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Detail Information
Publications
24-Hour monitoring of cortisol and corticotropin secretion in psychotic and nonpsychotic major depressionJ A Posener
Department of Psychiatry, Washington University School of Medicine, 660 S Euclid Ave, Box 8134, St Louis, MO 63110, USA
Arch Gen Psychiatry 57:755-60. 2000..Comparison of depressed patients with and without psychotic features is also important because HPA axis abnormalities may be especially pronounced in psychotic depressed patients...
Cortisol feedback during the HPA quiescent period in patients with major depressionJ A Posener
Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
Am J Psychiatry 158:2083-5. 2001..The authors tested the hypothesis that patients with major depression have a defect in the mechanism by which cortisol exerts negative feedback on the hypothalamic-pituitary-adrenal (HPA) axis during the HPA axis quiescent period...
High-dimensional mapping of the hippocampus in depressionJoel A Posener
Department of Psychiatry, Washington University School of Medicine, Campus Box 8134, 660 South Euclid Ave, St Louis, MO 63110, USA
Am J Psychiatry 160:83-9. 2003..In this study, high-dimensional brain mapping was used to evaluate hippocampal shape and volume in patients with major depressive disorder and healthy comparison subjects...
Process irregularity of cortisol and adrenocorticotropin secretion in men with major depressive disorderJoel A Posener
Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
Psychoneuroendocrinology 29:1129-37. 2004..Together, these results are most consistent with a primary abnormality of the adrenal gland and suggest that further investigation of adrenal gland physiology may be informative for the pathophysiology of depression...
Neuropsychological deficits in psychotic versus nonpsychotic major depression and no mental illnessA F Schatzberg
Department of Psychiatry, Stanford University, CA 94305 5717, USA
Am J Psychiatry 157:1095-100. 2000..The current study explored specific impairments in cognitive function in subjects with psychotic major depression, subjects with nonpsychotic major depression, and healthy comparison subjects studied under drug-free conditions...
Hippocampal deformities in schizophrenia characterized by high dimensional brain mappingJohn G Csernansky
Department of Psychiatry Box 8134, Washington University School of Medicine, 660 S Euclid Avenue, St Louis, MO 63110, USA
Am J Psychiatry 159:2000-6. 2002..High dimensional brain mapping, which utilizes probabilistic deformations of a neuroanatomical template, was used to characterize disease-related patterns of changes in hippocampal volume, shape, and asymmetry...
Abnormalities of thalamic volume and shape in schizophreniaJohn G Csernansky
Department of Psychiatry Box 8134, Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110, USA
Am J Psychiatry 161:896-902. 2004..However, the pattern of shape change associated with such volume loss has not been investigated. In this study, alterations in thalamic volume, shape, and symmetry were compared in subjects with and without schizophrenia...
