Jose A Pineda

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. pmc Depression of whole-brain oxygen extraction fraction is associated with poor outcome in pediatric traumatic brain injury
    Dustin K Ragan
    Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri, USA
    Pediatr Res 71:199-204. 2012
  2. doi request reprint Effect of implementation of a paediatric neurocritical care programme on outcomes after severe traumatic brain injury: a retrospective cohort study
    Jose A Pineda
    Department of Pediatrics, Division of Critical Care Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Lancet Neurol 12:45-52. 2013
  3. ncbi request reprint Clinical significance of alphaII-spectrin breakdown products in cerebrospinal fluid after severe traumatic brain injury
    Jose A Pineda
    Center for Traumatic Brain Injury Studies, E F and W L McKnight Brain Institute of the University of Florida, Gainesville, Florida, USA
    J Neurotrauma 24:354-66. 2007
  4. ncbi request reprint Cell-specific DNA fragmentation may be attenuated by a survivin-dependent mechanism after traumatic brain injury in rats
    Erik A Johnson
    Center for Traumatic Brain Injury Studies CTBIS, E F and W L McKnight Brain Institute of the University of Florida, Gainesville, FL 32610, USA
    Exp Brain Res 167:17-26. 2005
  5. pmc Alterations in cerebral oxygen metabolism after traumatic brain injury in children
    Dustin K Ragan
    Department of Pediatrics, Washington University School of Medicine, St Louis, MO, USA
    J Cereb Blood Flow Metab 33:48-52. 2013
  6. ncbi request reprint Rapid discovery of putative protein biomarkers of traumatic brain injury by SDS-PAGE-capillary liquid chromatography-tandem mass spectrometry
    William E Haskins
    Center of Neuroproteomics and Biomarkers Research, Department of Neuroscience, University of Florida, Gainesville, Florida 32610, USA
    J Neurotrauma 22:629-44. 2005
  7. ncbi request reprint Management of children with mild traumatic brain injury and intracranial hemorrhage
    Jacob K Greenberg
    From the Departments of Neurological Surgery J K G, I T S, T S P, M D S, J R L, D D L, and Pediatrics T S P, M D S, J R L, J C L, J A P, D D L, Washington University, St Louis, Missouri
    J Trauma Acute Care Surg 76:1089-95. 2014
  8. ncbi request reprint Biomarkers of proteolytic damage following traumatic brain injury
    Jose A Pineda
    Center for Traumatic Brain Injury Studies, Evelyn F and William L McKnight Brain Institute, University of Florida, Gainesville, FL, USA
    Brain Pathol 14:202-9. 2004
  9. ncbi request reprint Traumatic brain injury in children
    Jeffrey Leonard
    Department of Neurological Surgery, Division of Pediatric Neurosurgery, Washington University School of Medicine, USA
    Mo Med 105:404-11; quiz 411-2. 2008
  10. doi request reprint Physician agreement with evidence-based recommendations for the treatment of severe traumatic brain injury in children
    Nathan P Dean
    Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri, USA
    J Neurosurg 107:387-91. 2007

Detail Information

Publications13

  1. pmc Depression of whole-brain oxygen extraction fraction is associated with poor outcome in pediatric traumatic brain injury
    Dustin K Ragan
    Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri, USA
    Pediatr Res 71:199-204. 2012
    ....
  2. doi request reprint Effect of implementation of a paediatric neurocritical care programme on outcomes after severe traumatic brain injury: a retrospective cohort study
    Jose A Pineda
    Department of Pediatrics, Division of Critical Care Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Lancet Neurol 12:45-52. 2013
    ..Organisation of intensive-care units has an important role in pathway effectiveness. We aimed to assess the effect of a paediatric neurocritical care programme (PNCP) on outcomes for children with severe traumatic brain injury...
  3. ncbi request reprint Clinical significance of alphaII-spectrin breakdown products in cerebrospinal fluid after severe traumatic brain injury
    Jose A Pineda
    Center for Traumatic Brain Injury Studies, E F and W L McKnight Brain Institute of the University of Florida, Gainesville, Florida, USA
    J Neurotrauma 24:354-66. 2007
    ..Our data further suggests that both necrotic/oncotic and apoptotic cell death mechanisms are activated in humans following severe TBI, but with a different time course after injury...
  4. ncbi request reprint Cell-specific DNA fragmentation may be attenuated by a survivin-dependent mechanism after traumatic brain injury in rats
    Erik A Johnson
    Center for Traumatic Brain Injury Studies CTBIS, E F and W L McKnight Brain Institute of the University of Florida, Gainesville, FL 32610, USA
    Exp Brain Res 167:17-26. 2005
    ..These data suggest that survivin expression may attenuate DNA cleavage and cell death, and that this mechanism operates in a cell type-specific manner after TBI...
  5. pmc Alterations in cerebral oxygen metabolism after traumatic brain injury in children
    Dustin K Ragan
    Department of Pediatrics, Washington University School of Medicine, St Louis, MO, USA
    J Cereb Blood Flow Metab 33:48-52. 2013
    ..This finding is consistent with preclinical and adult clinical studies of brain metabolism and mitochondrial dysfunction after TBI...
  6. ncbi request reprint Rapid discovery of putative protein biomarkers of traumatic brain injury by SDS-PAGE-capillary liquid chromatography-tandem mass spectrometry
    William E Haskins
    Center of Neuroproteomics and Biomarkers Research, Department of Neuroscience, University of Florida, Gainesville, Florida 32610, USA
    J Neurotrauma 22:629-44. 2005
    ..e., TBI) without a priori knowledge of the molecules involved...
  7. ncbi request reprint Management of children with mild traumatic brain injury and intracranial hemorrhage
    Jacob K Greenberg
    From the Departments of Neurological Surgery J K G, I T S, T S P, M D S, J R L, D D L, and Pediatrics T S P, M D S, J R L, J C L, J A P, D D L, Washington University, St Louis, Missouri
    J Trauma Acute Care Surg 76:1089-95. 2014
    ..The purpose of this study was to test the hypothesis that we could identify a subset of children with traumatic ICH who could be monitored on a general neurosurgery ward with a low risk of clinical deterioration...
  8. ncbi request reprint Biomarkers of proteolytic damage following traumatic brain injury
    Jose A Pineda
    Center for Traumatic Brain Injury Studies, Evelyn F and William L McKnight Brain Institute, University of Florida, Gainesville, FL, USA
    Brain Pathol 14:202-9. 2004
    ....
  9. ncbi request reprint Traumatic brain injury in children
    Jeffrey Leonard
    Department of Neurological Surgery, Division of Pediatric Neurosurgery, Washington University School of Medicine, USA
    Mo Med 105:404-11; quiz 411-2. 2008
    ..Treatment and assessment aimed specifically toward the immature brain can improve both functional outcome and long-term psychosocial impairment...
  10. doi request reprint Physician agreement with evidence-based recommendations for the treatment of severe traumatic brain injury in children
    Nathan P Dean
    Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri, USA
    J Neurosurg 107:387-91. 2007
    ....
  11. ncbi request reprint Cell-specific upregulation of survivin after experimental traumatic brain injury in rats
    Erik A Johnson
    Center for Traumatic Brain Injury Studies, E F and W L McKnight Brain Institute of the University of Florida, 100 S Newell Drive, Gainesville, FL 32610, USA
    J Neurotrauma 21:1183-95. 2004
    ..In addition, the expression of survivin was co-incident with PCNA, a cell cycle protein. This suggests that survivin may be involved in regulation of neural cell proliferative responses after traumatic brain injury...
  12. ncbi request reprint Alpha-II spectrin breakdown products in aneurysmal subarachnoid hemorrhage: a novel biomarker of proteolytic injury
    Stephen B Lewis
    Department of Neurological Surgery, University of Florida, Gainesville 32610, USA
    J Neurosurg 107:792-6. 2007
    ..In addition, all spectrin breakdown products (SBDPs) can provide information on the proteolytic mechanisms of injury...
  13. ncbi request reprint Caring for the child with severe traumatic brain injury: old lessons learned and new concepts
    Jose A Pineda
    Pediatr Crit Care Med 7:496-7. 2006