Michele L Pergadia

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. pmc Genetic linkage findings for DSM-IV nicotine withdrawal in two populations
    Michele L Pergadia
    Department of Psychiatry, Washington University School of Medicine, Saint Louis, Missouri 63110, USA
    Am J Med Genet B Neuropsychiatr Genet 150:950-9. 2009
  2. pmc Nicotine withdrawal symptoms in adolescent and adult twins
    Michele L Pergadia
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    Twin Res Hum Genet 13:359-69. 2010
  3. pmc A 3p26-3p25 genetic linkage finding for DSM-IV major depression in heavy smoking families
    Michele L Pergadia
    Department of Psychiatry, WashingtonUniversity School of Medicine, Saint Louis, MO 63110, USA
    Am J Psychiatry 168:848-52. 2011
  4. pmc Parent, sibling and peer influences on smoking initiation, regular smoking and nicotine dependence. Results from a genetically informative design
    Jeffrey F Scherrer
    St Louis Veterans Affairs Medical Center, Research Service 151 JC, 915 North Grand Blvd, St Louis, MO 63106, USA
    Addict Behav 37:240-7. 2012
  5. pmc Alcohol consumption indices of genetic risk for alcohol dependence
    Julia D Grant
    Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Biol Psychiatry 66:795-800. 2009
  6. pmc H2 haplotype at chromosome 17q21.31 protects against childhood sexual abuse-associated risk for alcohol consumption and dependence
    Elliot C Nelson
    Department of Psychiatry, Washington University School of Medicine, USA
    Addict Biol 15:1-11. 2010
  7. pmc Further evidence for an association between the gamma-aminobutyric acid receptor A, subunit 4 genes on chromosome 4 and Fagerström Test for Nicotine Dependence
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Addiction 104:471-7. 2009
  8. pmc Smoking outcome expectancies in young adult female smokers: individual differences and associations with nicotine dependence in a genetically informative sample
    Sean D Kristjansson
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Drug Alcohol Depend 116:37-44. 2011
  9. pmc Evidence for an interaction between age at first drink and genetic influences on DSM-IV alcohol dependence symptoms
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid, St Louis, MO 63110, USA
    Alcohol Clin Exp Res 33:2047-56. 2009
  10. pmc A latent class analysis of DSM-IV and Fagerström (FTND) criteria for nicotine dependence
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Nicotine Tob Res 13:972-81. 2011

Detail Information

Publications33

  1. pmc Genetic linkage findings for DSM-IV nicotine withdrawal in two populations
    Michele L Pergadia
    Department of Psychiatry, Washington University School of Medicine, Saint Louis, Missouri 63110, USA
    Am J Med Genet B Neuropsychiatr Genet 150:950-9. 2009
    ..Other studies have reported that chromosome 11 may harbor genes associated with various aspects of smoking behavior. This study adds to that literature by highlighting evidence for NW...
  2. pmc Nicotine withdrawal symptoms in adolescent and adult twins
    Michele L Pergadia
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    Twin Res Hum Genet 13:359-69. 2010
    ....
  3. pmc A 3p26-3p25 genetic linkage finding for DSM-IV major depression in heavy smoking families
    Michele L Pergadia
    Department of Psychiatry, WashingtonUniversity School of Medicine, Saint Louis, MO 63110, USA
    Am J Psychiatry 168:848-52. 2011
    ..The authors tested for genetic linkage of DSM-IV-diagnosed major depressive disorder in families that were ascertained for cigarette smoking...
  4. pmc Parent, sibling and peer influences on smoking initiation, regular smoking and nicotine dependence. Results from a genetically informative design
    Jeffrey F Scherrer
    St Louis Veterans Affairs Medical Center, Research Service 151 JC, 915 North Grand Blvd, St Louis, MO 63106, USA
    Addict Behav 37:240-7. 2012
    ..Smoking interventions may have greatest impact by targeting smoking prevention among peer groups in adolescent and young adult populations...
  5. pmc Alcohol consumption indices of genetic risk for alcohol dependence
    Julia D Grant
    Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Biol Psychiatry 66:795-800. 2009
    ..A high genetic correlation between these measures would suggest that a continuous measure of consumption may have a useful role in the discovery of genes contributing to dependence risk...
  6. pmc H2 haplotype at chromosome 17q21.31 protects against childhood sexual abuse-associated risk for alcohol consumption and dependence
    Elliot C Nelson
    Department of Psychiatry, Washington University School of Medicine, USA
    Addict Biol 15:1-11. 2010
    ..Our results also suggest that severe early trauma may prove to be an important clinical covariate in the treatment of alcohol dependence...
  7. pmc Further evidence for an association between the gamma-aminobutyric acid receptor A, subunit 4 genes on chromosome 4 and Fagerström Test for Nicotine Dependence
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Addiction 104:471-7. 2009
    ..In the present report, we extend the previous study by expanding our genotyping efforts significantly for these two genes...
  8. pmc Smoking outcome expectancies in young adult female smokers: individual differences and associations with nicotine dependence in a genetically informative sample
    Sean D Kristjansson
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Drug Alcohol Depend 116:37-44. 2011
    ....
  9. pmc Evidence for an interaction between age at first drink and genetic influences on DSM-IV alcohol dependence symptoms
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid, St Louis, MO 63110, USA
    Alcohol Clin Exp Res 33:2047-56. 2009
    ..In this study, we examine whether age at first drink moderates genetic and environmental influences, via gene x environment interactions, on DSM-IV alcohol dependence symptoms...
  10. pmc A latent class analysis of DSM-IV and Fagerström (FTND) criteria for nicotine dependence
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Nicotine Tob Res 13:972-81. 2011
    ....
  11. pmc Early cannabis use and DSM-IV nicotine dependence: a twin study
    Arpana Agrawal
    Washington University School of Medicine, Department of Psychiatry, St Louis, MO 63110, USA
    Addiction 103:1896-904. 2008
    ..We examine whether cannabis use prior to age 17 years is associated with an increased likelihood of DSM-IV nicotine dependence and the extent to which genetic and environmental factors contribute to this association...
  12. pmc Contribution of parental psychopathology to offspring smoking and nicotine dependence in a genetically informative design
    Hong Xian
    Research Service 151JC, St Louis Veterans Affairs Medical Center, 915 North Grand Boulevard, St Louis, Missouri 63106, USA
    J Stud Alcohol Drugs 71:664-73. 2010
    ....
  13. pmc Drinking motives in female smokers: factor structure, alcohol dependence, and genetic influences
    Sean D Kristjansson
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Alcohol Clin Exp Res 35:345-54. 2011
    ....
  14. ncbi request reprint An autosomal linkage scan for cannabis use disorders in the nicotine addiction genetics project
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8134, St Louis, MO 63110, USA
    Arch Gen Psychiatry 65:713-21. 2008
    ..Despite accumulating evidence that there is a genetic basis for cannabis use disorders (ie, abuse and dependence), few studies have identified genomic regions that may harbor biological risk and protective factors...
  15. pmc Initial response to cigarettes predicts rate of progression to regular smoking: findings from an offspring-of-twins design
    Carolyn E Sartor
    Department of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8134, Saint Louis, Missouri 63110, USA
    Addict Behav 35:771-8. 2010
    ..exclusively negative (physiological) responses suggests the importance of considering both dimensions in combination to characterize risk for smoking-related outcomes...
  16. pmc Genetic linkage to chromosome 22q12 for a heavy-smoking quantitative trait in two independent samples
    Scott F Saccone
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Hum Genet 80:856-66. 2007
    ..Fine mapping of this linkage region may reveal variants contributing to heaviness of smoking, which will lead to a better understanding of the genetic mechanisms underlying nicotine dependence...
  17. pmc A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications
    Andrew C Heath
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Biol Psychiatry 70:513-8. 2011
    ....
  18. pmc Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes
    Nancy L Saccone
    Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Am J Med Genet B Neuropsychiatr Genet 150:453-66. 2009
    ....
  19. pmc Cannabinoid receptor genotype moderation of the effects of childhood physical abuse on anhedonia and depression
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Arch Gen Psychiatry 69:732-40. 2012
    ..The endocannabinoid system has been implicated in stress adaptation and the regulation of mood in rodent studies, but few human association studies have examined these links and replications are limited...
  20. pmc Developing a quantitative measure of alcohol consumption for genomic studies on prospective cohorts
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid Avenue, Box 8134, St Louis, Missouri 63110, USA
    J Stud Alcohol Drugs 70:157-68. 2009
    ..The purpose of this study was to develop a quantitative measure of alcohol consumption for gene-mapping studies...
  21. doi request reprint Correlates of cigarette smoking during pregnancy and its genetic and environmental overlap with nicotine dependence
    Arpana Agrawal
    Washington University School of Medicine, Department of Psychiatry, St Louis, MO 63110, USA
    Nicotine Tob Res 10:567-78. 2008
    ....
  22. ncbi request reprint Assortative mating for cigarette smoking and for alcohol consumption in female Australian twins and their spouses
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid, 8134, St Louis, MO 63110, USA
    Behav Genet 36:553-66. 2006
    ..We aim to clarify the mechanisms contributing to spousal similarity for cigarette smoking and alcohol consumption...
  23. pmc Simultaneous cannabis and tobacco use and cannabis-related outcomes in young women
    Arpana Agrawal
    Washington University School of Medicine, Department of Psychiatry, St Louis, MO 63110, USA
    Drug Alcohol Depend 101:8-12. 2009
    ....
  24. pmc Autosomal linkage analysis for cannabis use behaviors in Australian adults
    Arpana Agrawal
    Washington University School of Medicine, Department of Psychiatry, 660 South Euclid Avenue, St Louis, MO 63108, USA
    Drug Alcohol Depend 98:185-90. 2008
    ....
  25. ncbi request reprint Genetic analyses of DSM-IV nicotine withdrawal in adult twins
    Michele L Pergadia
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Psychol Med 36:963-72. 2006
    ....
  26. pmc Body mass index and regular smoking in young adult women
    Alexis E Duncan
    Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, United States
    Addict Behav 35:983-8. 2010
    ..57, 95% CI: 1.05-2.35 and OR=1.73, 95% CI: 1.35-2.20, respectively). These results suggest that experiencing CSA alters the association between BMI and regular smoking in women who have experimented with cigarettes...
  27. ncbi request reprint Genetic and environmental influences on extreme personality dispositions in adolescent female twins
    Michele L Pergadia
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    J Child Psychol Psychiatry 47:902-9. 2006
    ....
  28. pmc The effects of maternal smoking during pregnancy on offspring outcomes
    Arpana Agrawal
    Washington University School of Medicine, Dept of Psychiatry, Saint Louis, MO 63110, USA
    Prev Med 50:13-8. 2010
    ....
  29. ncbi request reprint The implications of simultaneous smoking initiation for inferences about the genetics of smoking behavior from twin data
    Michele L Pergadia
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63100, USA
    Behav Genet 36:567-76. 2006
    ..68%). These results indicate the important social influences that may occur for smoking initiation do not appear to seriously bias estimates of genetic effects on later stages of smoking...
  30. pmc Correlates of smoking cessation in a nationally representative sample of U.S. adults
    Arpana Agrawal
    Washington University School of Medicine, Department of Psychiatry, St Louis, Missouri 63110, USA
    Addict Behav 33:1223-6. 2008
    ....
  31. doi request reprint Gamma-aminobutyric acid receptor genes and nicotine dependence: evidence for association from a case-control study
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, USA
    Addiction 103:1027-38. 2008
    ....
  32. pmc Pathway analysis of smoking quantity in multiple GWAS identifies cholinergic and sensory pathways
    Oscar Harari
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, United States of America
    PLoS ONE 7:e50913. 2012
    ....
  33. ncbi request reprint Is there evidence for symptoms of cannabis withdrawal in the national epidemiologic survey of alcohol and related conditions?
    Arpana Agrawal
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Am J Addict 17:199-208. 2008
    ..Evidence from this and prior studies demonstrating withdrawal strongly suggest that future editions of DSM need to reconsider the exclusion of withdrawal from criteria for cannabis dependence...