O Lynne Nelson

Summary

Affiliation: Washington State University
Country: USA

Publications

  1. ncbi request reprint Echocardiographic and radiographic changes associated with systemic hypertension in cats
    Lynne Nelson
    Department of Veterinary Clinical Sciences, Washington State University, Pullman 99164 7060, USA
    J Vet Intern Med 16:418-25. 2002
  2. pmc Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy
    Michael H Radke
    Department of Neuromuscular and Cardiovascular Cell Biology, Max Delbruck Center for Molecular Medicine, D 13122 Berlin Buch, Germany
    Proc Natl Acad Sci U S A 104:3444-9. 2007
  3. pmc Titin isoform switching is a major cardiac adaptive response in hibernating grizzly bears
    O Lynne Nelson
    College of Veterinary Medicine, Washington State Univ, Pullman, WA 99164, USA
    Am J Physiol Heart Circ Physiol 295:H366-71. 2008
  4. ncbi request reprint The utility of plasma D-dimer to identify thromboembolic disease in dogs
    O Lynne Nelson
    Internal Medicine and Cardiology, Washington State University, Pullman, WA 99164 7060, USA
    J Vet Intern Med 17:830-4. 2003
  5. ncbi request reprint Comparison of echocardiography-guided and fluoroscopy-guided endomyocardial biopsy techniques
    O Lynne Nelson
    Department of Veterinary Clinical Sciences, Washington State University, Pullman, WA 99164 7060, USA
    Vet Radiol Ultrasound 46:131-4. 2005
  6. doi request reprint Cardiac function adaptations in hibernating grizzly bears (Ursus arctos horribilis)
    O Lynne Nelson
    Department of Veterinary Clinical Sciences, Washington State University, 100 Grimes Way, Room 17, Pullman, WA 99164, USA
    J Comp Physiol B 180:465-73. 2010
  7. ncbi request reprint The use of an implantable cardioverter defibrillator in a Boxer Dog to control clinical signs of arrhythmogenic right ventricular cardiomyopathy
    O Lynne Nelson
    Department of Veterinary Clinical Sciences, Washington State University, College of Veterinary Medicine, Pullman 99164, USA
    J Vet Intern Med 20:1232-7. 2006
  8. ncbi request reprint Effect of dietary astaxanthin at different stages of mammary tumor initiation in BALB/c mice
    Ruriko Nakao
    School of Food Science, Washington State University, Pullman, WA 99164, USA
    Anticancer Res 30:2171-5. 2010
  9. doi request reprint The aging myostatin null phenotype: reduced adiposity, cardiac hypertrophy, enhanced cardiac stress response, and sexual dimorphism
    Melissa F Jackson
    School of Molecular Biosciences, Department of Veterinary Microbiology and Pathology, 124 ASLB, Washington Center for Muscle Biology, Washington State University, Pullman, Washington 99164, USA
    J Endocrinol 213:263-75. 2012
  10. ncbi request reprint Evaluation of cardiac function in active and hibernating grizzly bears
    O Lynne Nelson
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA
    J Am Vet Med Assoc 223:1170-5. 2003

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Echocardiographic and radiographic changes associated with systemic hypertension in cats
    Lynne Nelson
    Department of Veterinary Clinical Sciences, Washington State University, Pullman 99164 7060, USA
    J Vet Intern Med 16:418-25. 2002
    ..The distal aortic root measurements and ratios evaluated by echocardiography were significantly different between the 2 groups of cats (P = .0001) and were significantly correlated with SBP (P = .0001) but not age (P > .3)...
  2. pmc Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy
    Michael H Radke
    Department of Neuromuscular and Cardiovascular Cell Biology, Max Delbruck Center for Molecular Medicine, D 13122 Berlin Buch, Germany
    Proc Natl Acad Sci U S A 104:3444-9. 2007
    ..The N2B-KO mouse is the first titin-based model of diastolic dysfunction and, considering the high prevalence of diastolic heart failure, it could provide future mechanistic insights into the disease process...
  3. pmc Titin isoform switching is a major cardiac adaptive response in hibernating grizzly bears
    O Lynne Nelson
    College of Veterinary Medicine, Washington State Univ, Pullman, WA 99164, USA
    Am J Physiol Heart Circ Physiol 295:H366-71. 2008
    ..Thus our work identified changes in the alternative splicing of cardiac titin as a major adaptive response in hibernating grizzly bears...
  4. ncbi request reprint The utility of plasma D-dimer to identify thromboembolic disease in dogs
    O Lynne Nelson
    Internal Medicine and Cardiology, Washington State University, Pullman, WA 99164 7060, USA
    J Vet Intern Med 17:830-4. 2003
    ..5% (sensitivity, 36%). FDPs were not high in any TE patient; thus, they may be an insensitive indicator of thromboembolism, with or without overt disseminated intravascular coagulation (DIC)...
  5. ncbi request reprint Comparison of echocardiography-guided and fluoroscopy-guided endomyocardial biopsy techniques
    O Lynne Nelson
    Department of Veterinary Clinical Sciences, Washington State University, Pullman, WA 99164 7060, USA
    Vet Radiol Ultrasound 46:131-4. 2005
    ..Clear definition of endocardial surface as afforded by echocardiography may enhance tissue sample quality and lower potential complications from this procedure...
  6. doi request reprint Cardiac function adaptations in hibernating grizzly bears (Ursus arctos horribilis)
    O Lynne Nelson
    Department of Veterinary Clinical Sciences, Washington State University, 100 Grimes Way, Room 17, Pullman, WA 99164, USA
    J Comp Physiol B 180:465-73. 2010
    ..These findings will aid in rational approaches to identifying underlying molecular mechanisms...
  7. ncbi request reprint The use of an implantable cardioverter defibrillator in a Boxer Dog to control clinical signs of arrhythmogenic right ventricular cardiomyopathy
    O Lynne Nelson
    Department of Veterinary Clinical Sciences, Washington State University, College of Veterinary Medicine, Pullman 99164, USA
    J Vet Intern Med 20:1232-7. 2006
  8. ncbi request reprint Effect of dietary astaxanthin at different stages of mammary tumor initiation in BALB/c mice
    Ruriko Nakao
    School of Food Science, Washington State University, Pullman, WA 99164, USA
    Anticancer Res 30:2171-5. 2010
    ..This suggests that an adequate blood astaxanthin status is needed to protect against tumor initiation; conversely, astaxanthin supplementation after tumor initiation may be contraindicated...
  9. doi request reprint The aging myostatin null phenotype: reduced adiposity, cardiac hypertrophy, enhanced cardiac stress response, and sexual dimorphism
    Melissa F Jackson
    School of Molecular Biosciences, Department of Veterinary Microbiology and Pathology, 124 ASLB, Washington Center for Muscle Biology, Washington State University, Pullman, Washington 99164, USA
    J Endocrinol 213:263-75. 2012
    ..Additional studies are nevertheless needed to definitively assess potential risks to cardiac function...
  10. ncbi request reprint Evaluation of cardiac function in active and hibernating grizzly bears
    O Lynne Nelson
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA
    J Am Vet Med Assoc 223:1170-5. 2003
    ..To evaluate cardiac function parameters in a group of active and hibernating grizzly bears...
  11. doi request reprint Temporal organization of activity in the brown bear (Ursus arctos): roles of circadian rhythms, light, and food entrainment
    Jasmine V Ware
    Departments of Veterinary Comparative Anatomy, Pharmacology, and Physiology, Washington State Univ, Pullman, WA 99164, USA
    Am J Physiol Regul Integr Comp Physiol 303:R890-902. 2012
    ..Activity shifted entirely to a nocturnal pattern. Thus daily activity in brown bears is highly modifiable by photoperiod and food availability in a stereotypic seasonal fashion...
  12. doi request reprint Minimal seasonal alterations in the skeletal muscle of captive brown bears
    John D Hershey
    Department of Veterinary Comparative Anatomy, Pharmacology and Physiology, Washington State University, Pullman, Washington 99164, USA
    Physiol Biochem Zool 81:138-47. 2008
    ..These results agreed with a study that showed minimal skeletal muscle atrophy between seasons in wild black bears...
  13. ncbi request reprint Effect of astaxanthin supplementation on inflammation and cardiac function in BALB/c mice
    Ruriko Nakao
    School of Food Science, Washington State University, Pullman, WA 99164, USA
    Anticancer Res 30:2721-5. 2010
    ..08% astaxanthin had higher (p<0.05) heart mitochondrial membrane potential and contractility index compared to the control group. These results support the possible use of dietary astaxanthin for cardiac protection...
  14. pmc Energy homeostasis regulatory peptides in hibernating grizzly bears
    Janos Gardi
    First Department of Internal Medicine, University of Szeged, Koranyi fasor 8 10, H 6720 Szeged, Hungary
    Gen Comp Endocrinol 172:181-3. 2011
    ..Our results suggest that ghrelin plays a potential role in the regulation of metabolic changes and energy homeostasis during hibernation in grizzly bears...
  15. doi request reprint Split parturition observed in a captive North American brown bear (Ursus arctos)
    Jasmine V Ware
    Deparmentt of Veterinary and Comparative Anatomy, Pharmacology and Physiology VCAPP, Washington State University, Pullman, Washington, USA
    Zoo Biol 31:255-9. 2012
    ..When normalized to age, cub growth rates did not differ. To our knowledge, this is the first documented case of markedly different birth dates in a single litter of brown bear cubs...
  16. ncbi request reprint Use of the D-dimer assay for diagnosing thromboembolic disease in the dog
    O Lynne Nelson
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington 99194, USA
    J Am Anim Hosp Assoc 41:145-9. 2005
    ..This paper examines the use of D-dimer assays and other clinical modalities in the diagnostic approach to thromboembolic disease in small animals...
  17. pmc Myostatin represses physiological hypertrophy of the heart and excitation-contraction coupling
    Buel D Rodgers
    Department of Animal Sciences and School of Molecular BioSciences, Washington State University, Pullman, WA 99164, USA
    J Physiol 587:4873-86. 2009
    ..Thus, the controlled inhibition of myostatin action could potentially help repair damaged cardiac muscle by inducing physiological hypertrophy...
  18. ncbi request reprint Cardiovascular dysfunction in dogs associated with critical illnesses
    O Lynne Nelson
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington 99164 7060, USA
    J Am Anim Hosp Assoc 42:344-9. 2006
    ..Fifteen dogs were presented with generalized weakness as a part of their clinical complaint. Twelve (75%) of 16 dogs died or were euthanized within 15 days of admission to the hospital. The average time until death was 3.6 days...
  19. ncbi request reprint Disease association and clinical assessment of feline pericardial effusion
    Benjamin J Davidson
    Department of Veterinary Clinical Sciences, Veterinary Teaching Hospital, Washington State University, P O Box 647060, Pullman, Washington 99164, USA
    J Am Anim Hosp Assoc 44:5-9. 2008
    ..Feline pericardial effusion remains an infrequent diagnosis, but its clinical relevance and association with severe cardiac and extracardiac disease warrant diagnostic evaluation...
  20. pmc Decreased bone turnover with balanced resorption and formation prevent cortical bone loss during disuse (hibernation) in grizzly bears (Ursus arctos horribilis)
    Meghan E McGee
    Department of Biomedical Engineering, Michigan Technological University, Houghton, MI 49931, USA
    Bone 42:396-404. 2008
    ..These results support the idea that bears possess a biological mechanism to prevent disuse osteoporosis...