R T Naismith

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. pmc Spinal cord tract diffusion tensor imaging reveals disability substrate in demyelinating disease
    Robert T Naismith
    Department of Neurology, Washington University, St Louis, MO, USA
    Neurology 80:2201-9. 2013
  2. pmc Acute and bilateral blindness due to optic neuropathy associated with copper deficiency
    Robert T Naismith
    Department of Neurology, Washington University, Campus Box 8111, 660 S Euclid Ave, St Louis, MO 63110, USA
    Arch Neurol 66:1025-7. 2009
  3. pmc Diffusion tensor imaging in acute optic neuropathies: predictor of clinical outcomes
    Robert T Naismith
    Department of Neurology, Washington University in St Louis, Campus Box 8111, 660 S Euclid Ave, St Louis, MO 63110, USA
    Arch Neurol 69:65-71. 2012
  4. pmc Rituximab add-on therapy for breakthrough relapsing multiple sclerosis: a 52-week phase II trial
    R T Naismith
    Department of Neurology, Washington University, St Louis, MO, USA
    Neurology 74:1860-7. 2010
  5. pmc Radial diffusivity in remote optic neuritis discriminates visual outcomes
    R T Naismith
    Neurology, Washington University, St Louis, MO 63110, USA
    Neurology 74:1702-10. 2010
  6. pmc Increased diffusivity in acute multiple sclerosis lesions predicts risk of black hole
    R T Naismith
    Neurology, Washington University, St Louis, MO 63110, USA
    Neurology 74:1694-701. 2010
  7. pmc Disability in optic neuritis correlates with diffusion tensor-derived directional diffusivities
    R T Naismith
    Department of Neurology, Washington University, Saint Louis, MO, USA
    Neurology 72:589-94. 2009
  8. pmc Optical coherence tomography differs in neuromyelitis optica compared with multiple sclerosis
    R T Naismith
    Department of Neurology, Washington University, Box 8111, 660 S Euclid Ave, St Louis, MO 63110, USA
    Neurology 72:1077-82. 2009
  9. pmc Optical coherence tomography is less sensitive than visual evoked potentials in optic neuritis
    R T Naismith
    Department of Neurology, Washington University, St Louis, MO 63110, USA
    Neurology 73:46-52. 2009
  10. ncbi request reprint Established and novel disease-modifying treatments in multiple sclerosis
    A H Cross
    Department of Neurology, Washington University, St Louis, MO, USA
    J Intern Med 275:350-63. 2014

Research Grants

Detail Information

Publications19

  1. pmc Spinal cord tract diffusion tensor imaging reveals disability substrate in demyelinating disease
    Robert T Naismith
    Department of Neurology, Washington University, St Louis, MO, USA
    Neurology 80:2201-9. 2013
    ..This study assessed the tissue integrity of major cervical cord tracts by using diffusion tensor imaging (DTI) to determine the relationship with specific clinical functions carried by those tracts...
  2. pmc Acute and bilateral blindness due to optic neuropathy associated with copper deficiency
    Robert T Naismith
    Department of Neurology, Washington University, Campus Box 8111, 660 S Euclid Ave, St Louis, MO 63110, USA
    Arch Neurol 66:1025-7. 2009
    ..Acquired copper deficiency in adults is associated with a subacute to chronic progressive myeloneuropathy and optic neuropathy...
  3. pmc Diffusion tensor imaging in acute optic neuropathies: predictor of clinical outcomes
    Robert T Naismith
    Department of Neurology, Washington University in St Louis, Campus Box 8111, 660 S Euclid Ave, St Louis, MO 63110, USA
    Arch Neurol 69:65-71. 2012
    ..To evaluate directional diffusivities within the optic nerve in a first event of acute optic neuritis to determine whether decreased axial diffusivity (AD) would predict 6-month visual outcome and optic nerve integrity measures...
  4. pmc Rituximab add-on therapy for breakthrough relapsing multiple sclerosis: a 52-week phase II trial
    R T Naismith
    Department of Neurology, Washington University, St Louis, MO, USA
    Neurology 74:1860-7. 2010
    ....
  5. pmc Radial diffusivity in remote optic neuritis discriminates visual outcomes
    R T Naismith
    Neurology, Washington University, St Louis, MO 63110, USA
    Neurology 74:1702-10. 2010
    ....
  6. pmc Increased diffusivity in acute multiple sclerosis lesions predicts risk of black hole
    R T Naismith
    Neurology, Washington University, St Louis, MO 63110, USA
    Neurology 74:1694-701. 2010
    ..We hypothesize that DTI can quantify the damage within acute multiple sclerosis (MS) white matter lesions to predict gadolinium (Gd)-enhancing lesions that will persist 12 months later as T1 hypointensities...
  7. pmc Disability in optic neuritis correlates with diffusion tensor-derived directional diffusivities
    R T Naismith
    Department of Neurology, Washington University, Saint Louis, MO, USA
    Neurology 72:589-94. 2009
    ....
  8. pmc Optical coherence tomography differs in neuromyelitis optica compared with multiple sclerosis
    R T Naismith
    Department of Neurology, Washington University, Box 8111, 660 S Euclid Ave, St Louis, MO 63110, USA
    Neurology 72:1077-82. 2009
    ..Optical coherence tomography (OCT), by measuring retinal nerve fiber layer (RNFL) as a surrogate of axonal injury, has potential to discriminate between these two conditions...
  9. pmc Optical coherence tomography is less sensitive than visual evoked potentials in optic neuritis
    R T Naismith
    Department of Neurology, Washington University, St Louis, MO 63110, USA
    Neurology 73:46-52. 2009
    ....
  10. ncbi request reprint Established and novel disease-modifying treatments in multiple sclerosis
    A H Cross
    Department of Neurology, Washington University, St Louis, MO, USA
    J Intern Med 275:350-63. 2014
    ....
  11. ncbi request reprint Phenotype and prognosis in African-Americans with multiple sclerosis: a retrospective chart review
    R T Naismith
    Department of Neurology, John L Trotter MS Center, Box 8111, Washington University, 660 South Euclid Avenue, Saint Louis, MO 63110, USA
    Mult Scler 12:775-81. 2006
    ..A phenotype of opticospinal MS has been proposed by some publications...
  12. pmc The present efficacy of multiple sclerosis therapeutics: Is the new 66% just the old 33%?
    Eric C Klawiter
    Department of Neurology, Washington University, St Louis, MO 63110, USA
    Neurology 73:984-90. 2009
    ..In this article, we debate the relative efficacy of natalizumab vs the older injectable therapies...
  13. pmc Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation
    Laura Piccio
    Department of Neurology and Neurosurgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Brain 131:3081-91. 2008
    ..The elevated levels of sTREM-2 in CSF of multiple sclerosis patients may inhibit the anti-inflammatory function of the membrane-bound receptor suggesting sTREM-2 to be a possible target for future therapies...
  14. ncbi request reprint Higher IgG index found in African Americans versus Caucasians with multiple sclerosis
    John R Rinker
    Department of Neurology and Neurosurgery, Washington University School of Medicine, St Louis, MO, USA
    Neurology 69:68-72. 2007
    ..Interethnic immunologic differences in MS and their relationship to disease-related disability have not been described...
  15. pmc Changes in B- and T-lymphocyte and chemokine levels with rituximab treatment in multiple sclerosis
    Laura Piccio
    Department of Neurology, Washington University School of Medicine, St Louis, MO, USA
    Arch Neurol 67:707-14. 2010
    ..B cells are implicated in the pathogenesis of multiple sclerosis. A beneficial effect of B-cell depletion using rituximab has been shown, but the complete mechanism of action for this drug is unclear...
  16. pmc Assessing optic nerve pathology with diffusion MRI: from mouse to human
    Junqian Xu
    Department of Neurology, Washington University in St Louis, St Louis, MO, USA
    NMR Biomed 21:928-40. 2008
    ..From different mouse models of optic nerve injuries to the emerging studies on patients with optic neuritis, directional diffusivities show great potential to be specific biomarkers for axonal and myelin injury...
  17. pmc Spinal cord ring enhancement in multiple sclerosis
    Eric C Klawiter
    Department of Neurology, Washington University, St Louis, Missouri, USA
    Arch Neurol 67:1395-8. 2010
    ..To describe the clinical and imaging characteristics of spinal cord ring enhancement in multiple sclerosis (MS)...
  18. ncbi request reprint Multiple sclerosis and black holes: connecting the pixels
    Robert T Naismith
    Arch Neurol 62:1666-8. 2005
  19. ncbi request reprint Does the hepatitis B vaccine cause multiple sclerosis?
    Robert T Naismith
    Neurology 63:772-3. 2004

Research Grants2

  1. Diffusion Imaging of Axonal Loss in the Optic Nerves
    Robert Naismith; Fiscal Year: 2007
    ..Tests of visual function will include those included in Aim 3. Aim 5 will determine the range of values for diffusivity parameters of normal optic nerves in healthy volunteers stratified by age and gender. ..