Genomes and Genes
Jeffrey H Miner
Affiliation: Washington University School of Medicine
- Miner J, Li C, Patton B. Laminins alpha2 and alpha4 in pancreatic acinar basement membranes are required for basal receptor localization. J Histochem Cytochem. 2004;52:153-6 pubmed..Importantly, these laminins were required for proper basal localization on acinar cells of two laminin receptors, dystroglycan and integrin alpha6beta4 . ..
- Miner J, Go G, Cunningham J, Patton B, Jarad G. Transgenic isolation of skeletal muscle and kidney defects in laminin beta2 mutant mice: implications for Pierson syndrome. Development. 2006;133:967-75 pubmed..We conclude that muscle defects in Lamb2(-/-) mice are responsible for the severe failure to thrive phenotype, and that renal replacement therapy alone will be an inadequate treatment for Pierson syndrome. ..
- Lin M, Miner J. Fatty acid transport protein 1 can compensate for fatty acid transport protein 4 in the developing mouse epidermis. J Invest Dermatol. 2015;135:462-470 pubmed publisher..These results suggest that increasing expression of FATP1 in suprabasal keratinocytes could normalize the skin of IPS patients and perhaps prevent the atopic manifestations. ..
- Miner J, Li C, Mudd J, Go G, Sutherland A. Compositional and structural requirements for laminin and basement membranes during mouse embryo implantation and gastrulation. Development. 2004;131:2247-56 pubmed..These data suggest that both the molecular composition and the integrity of basement membranes are crucial for early developmental events. ..