Gregory E Miller

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Chronic psychological stress and the regulation of pro-inflammatory cytokines: a glucocorticoid-resistance model
    Gregory E Miller
    Department of Psychology, Washington University, St Louis, Missouri 63130, USA
    Health Psychol 21:531-41. 2002
  2. ncbi request reprint Clinical depression and inflammatory risk markers for coronary heart disease
    Gregory E Miller
    Department of Psychology, Washington University, St Louis, Missouri 63130, USA
    Am J Cardiol 90:1279-83. 2002
  3. pmc Heart rate variability and markers of inflammation and coagulation in depressed patients with coronary heart disease
    Robert M Carney
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    J Psychosom Res 62:463-7. 2007
  4. ncbi request reprint Pathways linking depression, adiposity, and inflammatory markers in healthy young adults
    Gregory E Miller
    Department of Psychology, Washington University, Campus Box 1125, One Brookings Drive, St Louis, MO 63130, USA
    Brain Behav Immun 17:276-85. 2003
  5. pmc Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk
    Sheldon Cohen
    Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA
    Proc Natl Acad Sci U S A 109:5995-9. 2012
  6. ncbi request reprint Cynical hostility, depressive symptoms, and the expression of inflammatory risk markers for coronary heart disease
    Gregory E Miller
    Department of Psychology, Washington University, Saint Louis, Missouri, USA
    J Behav Med 26:501-15. 2003
  7. doi request reprint Biologic cost of caring for a cancer patient: dysregulation of pro- and anti-inflammatory signaling pathways
    Nicolas Rohleder
    Brandeis University, Department of Psychology, Waltham, MA 02454, USA
    J Clin Oncol 27:2909-15. 2009
  8. ncbi request reprint Depression and obstructive sleep apnea in patients with coronary heart disease
    Robert M Carney
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Psychosom Med 68:443-8. 2006
  9. ncbi request reprint Psychological stress and disease
    Sheldon Cohen
    Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
    JAMA 298:1685-7. 2007
  10. ncbi request reprint Loneliness, social network size, and immune response to influenza vaccination in college freshmen
    Sarah D Pressman
    Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA
    Health Psychol 24:297-306. 2005

Detail Information

Publications42

  1. ncbi request reprint Chronic psychological stress and the regulation of pro-inflammatory cytokines: a glucocorticoid-resistance model
    Gregory E Miller
    Department of Psychology, Washington University, St Louis, Missouri 63130, USA
    Health Psychol 21:531-41. 2002
    ..Findings suggest a novel pathway by which chronic stress might alter the course of inflammatory disease...
  2. ncbi request reprint Clinical depression and inflammatory risk markers for coronary heart disease
    Gregory E Miller
    Department of Psychology, Washington University, St Louis, Missouri 63130, USA
    Am J Cardiol 90:1279-83. 2002
    ..Increased body mass appears to be partially, although not completely, responsible for this relation...
  3. pmc Heart rate variability and markers of inflammation and coagulation in depressed patients with coronary heart disease
    Robert M Carney
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    J Psychosom Res 62:463-7. 2007
    ..Cardiac autonomic nervous system (ANS) dysregulation, proinflammatory processes, and procoagulant processes have been suggested as possible explanations...
  4. ncbi request reprint Pathways linking depression, adiposity, and inflammatory markers in healthy young adults
    Gregory E Miller
    Department of Psychology, Washington University, Campus Box 1125, One Brookings Drive, St Louis, MO 63130, USA
    Brain Behav Immun 17:276-85. 2003
    ..99; NNFI =.99; RMSEA =.05). It did not support a sickness behavior model in which the inflammatory molecules arising from expanded adipose tissue promote depressive symptoms...
  5. pmc Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk
    Sheldon Cohen
    Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA
    Proc Natl Acad Sci U S A 109:5995-9. 2012
    ..Because inflammation plays an important role in the onset and progression of a wide range of diseases, this model may have broad implications for understanding the role of stress in health...
  6. ncbi request reprint Cynical hostility, depressive symptoms, and the expression of inflammatory risk markers for coronary heart disease
    Gregory E Miller
    Department of Psychology, Washington University, Saint Louis, Missouri, USA
    J Behav Med 26:501-15. 2003
    ..These findings highlight the importance of considering both the independent and interactive relationships among psychosocial characteristics involved in disease...
  7. doi request reprint Biologic cost of caring for a cancer patient: dysregulation of pro- and anti-inflammatory signaling pathways
    Nicolas Rohleder
    Brandeis University, Department of Psychology, Waltham, MA 02454, USA
    J Clin Oncol 27:2909-15. 2009
    ..This study observed familial caregivers of patients with brain cancer for a year after diagnosis and tracked changes in neurohormonal and inflammatory processes...
  8. ncbi request reprint Depression and obstructive sleep apnea in patients with coronary heart disease
    Robert M Carney
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Psychosom Med 68:443-8. 2006
    ..Obstructive sleep apnea/hypopnea syndrome (OSAHS) is frequently comorbid with depression and is also a risk factor for cardiac events. Undetected OSAHS could help explain the increased risk associated with depression...
  9. ncbi request reprint Psychological stress and disease
    Sheldon Cohen
    Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
    JAMA 298:1685-7. 2007
  10. ncbi request reprint Loneliness, social network size, and immune response to influenza vaccination in college freshmen
    Sarah D Pressman
    Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA
    Health Psychol 24:297-306. 2005
    ..None of these variables were associated with social network size, and hence none were potential mediators of the relation between network size and immunization response...
  11. ncbi request reprint Depression as a risk factor for cardiac mortality and morbidity: a review of potential mechanisms
    Robert M Carney
    Department of Psychiatry, Suite 420, Behavioral Medicine Center, Washington University School of Medicine, 4625 Lindell Boulevard, St Louis, MO 63108, USA
    J Psychosom Res 53:897-902. 2002
    ..inflammatory processes. Despite recent advances in our understanding of these potential mechanisms, further research is needed to determine how depression increases risk for cardiac morbidity and mortality...
  12. doi request reprint Depression and hypothalamic-pituitary-adrenal activation: a quantitative summary of four decades of research
    Cinnamon Stetler
    Department of Psychology, Furman University, 3300 Poinsett Hwy, Greenville, SC 29613, USA
    Psychosom Med 73:114-26. 2011
    ..These sources include methodological differences between studies, as well as demographic or clinical differences between depressed samples...
  13. pmc Psychological stress and the human immune system: a meta-analytic study of 30 years of inquiry
    Suzanne C Segerstrom
    Department of Psychology, University of Kentucky, Lexington, KY 40506, USA
    Psychol Bull 130:601-30. 2004
    ..loss). Subjective reports of stress generally did not associate with immune change. In some cases, physical vulnerability as a function of age or disease also increased vulnerability to immune change during stressors...
  14. ncbi request reprint Differentiating the impact of episodic and chronic stressors on hypothalamic-pituitary-adrenocortical axis regulation in young women
    Teresa J Marin
    Department of Psychology, University of British Columbia, Vancouver, BC, Canada
    Health Psychol 26:447-55. 2007
    ..To explore the potential downstream consequences of altered HPA dynamics, the authors also assessed indicators of metabolic control and systemic inflammation...
  15. ncbi request reprint Where there is depression, there is inflammation... sometimes!
    Alexander H Glassman
    Biol Psychiatry 62:280-1. 2007
  16. ncbi request reprint If it goes up, must it come down? Chronic stress and the hypothalamic-pituitary-adrenocortical axis in humans
    Gregory E Miller
    Department of Psychology, University of British Columbia UBC, Vancouver, BC, Canada
    Psychol Bull 133:25-45. 2007
    ..Finally, HPA activity is shaped by a person's response to the situation; it increases with subjective distress but is lower in persons with posttraumatic stress disorder...
  17. ncbi request reprint Acute deviations from long-term trait depressive symptoms predict systemic inflammatory activity
    Nicolas Rohleder
    Department of Psychology, University of British Columbia, 2136 West Mall, Vancouver, BC, Canada
    Brain Behav Immun 22:709-16. 2008
    ..While higher levels of inflammatory mediators have been found in dysphoric individuals, it is not known whether long-term or short-term mood changes are responsible for this phenomenon...
  18. pmc Parent psychological states predict changes in inflammatory markers in children with asthma and healthy children
    Jutta M Wolf
    University of British Columbia, Department of Psychology, 2136 West Mall, Vancouver, BC, Canada
    Brain Behav Immun 22:433-41. 2008
    ..These changes in inflammatory makers may represent one biological mechanism underlying the association between parental distress and child asthma morbidity...
  19. doi request reprint Symptoms of depression and impaired endothelial function in healthy adolescent women
    Lianne M Tomfohr
    Department of Psychology, University of British Columbia, Vancouver, BC, Canada
    J Behav Med 31:137-43. 2008
    ..Most patients in our sample had subclinical depressive symptoms, suggesting that even mild affective difficulties are capable of negatively influencing endothelial function in otherwise healthy youngsters...
  20. doi request reprint What do trajectories of childhood socioeconomic status tell us about markers of cardiovascular health in adolescence?
    Teresa J Marin
    Department of Psychology, University of British Columbia, 2136 West Mall, Vancouver, BC, Canada V6T 1Z4
    Psychosom Med 70:152-9. 2008
    ....
  21. pmc A functional genomic fingerprint of chronic stress in humans: blunted glucocorticoid and increased NF-kappaB signaling
    Gregory E Miller
    Department of Psychology, University of British Columbia, Vancouver, Canada
    Biol Psychiatry 64:266-72. 2008
    ..Chronic stressors are known to increase vulnerability to medical illness, but the mechanisms underlying this phenomenon are poorly understood...
  22. ncbi request reprint Applying mixed regression models to the analysis of repeated-measures data in psychosomatic medicine
    Ekin Blackwell
    University of British Columbia, Department of Psychology, 2136 West Mall, Vancouver, BC V6T 1Z4, Canada
    Psychosom Med 68:870-8. 2006
    ..The goal of this article is to introduce readers to mixed regression models, which provide a more flexible and accurate framework for managing repeated-measures data...
  23. ncbi request reprint Physical health problems, depressive mood, and cortisol secretion in old age: buffer effects of health engagement control strategies
    Carsten Wrosch
    Department of Psychology, Centre for Research in Human Development, Concordia University, and Douglas Hospital Research Center, Montreal, Quebec, Canada
    Health Psychol 26:341-9. 2007
    ..It was expected that adaptive levels of HECS would buffer the adverse effects of physical health problems on depressive mood and diurnal cortisol secretion...
  24. ncbi request reprint Adaptive self-regulation of unattainable goals: goal disengagement, goal reengagement, and subjective well-being
    Carsten Wrosch
    Department of Psychology, Concordia University, Montreal, QC, Canada
    Pers Soc Psychol Bull 29:1494-508. 2003
    ..In addition, the results showed that goal disengagement and goal reengagement can have interactive effects on subjective well-being. The importance of the findings for effective self-regulation and successful development are discussed...
  25. ncbi request reprint Psychological stress and antibody response to influenza vaccination: when is the critical period for stress, and how does it get inside the body?
    Gregory E Miller
    Department of Psychology, University of British Columbia, Vancouver, Canada
    Psychosom Med 66:215-23. 2004
    ....
  26. ncbi request reprint Relation of depressive symptoms to C-reactive protein and pathogen burden (cytomegalovirus, herpes simplex virus, Epstein-Barr virus) in patients with earlier acute coronary syndromes
    Gregory E Miller
    Department of Psychology, University of British Columbia, Vancouver, British Columbia, Canada
    Am J Cardiol 95:317-21. 2005
    ..In doing so, they highlight a mechanism through which depressive symptoms might foster morbidity and mortality among patients who have cardiac disease...
  27. ncbi request reprint Clinical depression and regulation of the inflammatory response during acute stress
    Gregory E Miller
    Department of Psychology, University of British Columbia, Vancouver, British Columbia, Canada
    Psychosom Med 67:679-87. 2005
    ..This study examined whether clinical depression is associated with a differential inflammatory response to an acute bout of psychological stress...
  28. ncbi request reprint Depressive symptoms and the regulation of proinflammatory cytokine expression in patients with coronary heart disease
    Gregory E Miller
    Department of Psychology, University of British Columbia, 2136 West Mall, Vancouver BC, Canada V6T 1Z4
    J Psychosom Res 59:231-6. 2005
    ..This study examined whether depressive symptoms are associated with the dysregulation of inflammatory cytokine production in response to an in vitro infectious challenge...
  29. ncbi request reprint Socioeconomic status and inflammatory processes in childhood asthma: the role of psychological stress
    Edith Chen
    Department of Psychology, University of British Columbia, Vancouver, Canada
    J Allergy Clin Immunol 117:1014-20. 2006
    ..Although social environment variables such as socioeconomic status (SES) have been linked to childhood asthma, little is known about the psychobiological mechanisms underlying this relationship...
  30. ncbi request reprint Regret intensity, diurnal cortisol secretion, and physical health in older individuals: evidence for directional effects and protective factors
    Carsten Wrosch
    Department of Psychology, Centre for Research in Human Development, Concordia University, Montreal, PQ, Canada
    Psychol Aging 22:319-30. 2007
    ..In addition, the intervention evidenced a beneficial effect on the association between initial regret intensity and increased sleep problems over time...
  31. pmc Life stress and diminished expression of genes encoding glucocorticoid receptor and beta2-adrenergic receptor in children with asthma
    Gregory E Miller
    Department of Psychology, University of British Columbia, 2136 West Mall, Vancouver, BC, Canada V6T 1Z4
    Proc Natl Acad Sci U S A 103:5496-501. 2006
    ..To the extent that it diminishes sensitivity to the antiinflammatory properties of glucocorticoids or the bronchodilatory properties of beta-agonists, this process could explain the increased asthma morbidity associated with stress...
  32. ncbi request reprint Uncoupling of social zeitgebers and diurnal cortisol secretion in clinical depression
    Cinnamon Stetler
    Department of Psychology, University of British Columbia, 2136 West Mall, Vancouver, BC, Canada V6T 1Z4
    Psychoneuroendocrinology 29:1250-9. 2004
    ..This lack of social entrainment may underlie some of the circadian disturbances in depression...
  33. ncbi request reprint Is it beneficial to involve a family member? A meta-analysis of psychosocial interventions for chronic illness
    Lynn M Martire
    University of Pittsburgh, Department of Psychiatry and University Center for Social and Urban Research, Pittsburgh, PA 15260, USA
    Health Psychol 23:599-611. 2004
    ..Although statistically significant aggregate effects were found, they were generally small in magnitude. These findings provide guidance in developing future interventions in this area...
  34. ncbi request reprint Social integration of daily activities and cortisol secretion: a laboratory based manipulation
    Cinnamon A Stetler
    Furman University, Greenville, SC, USA
    J Behav Med 31:249-57. 2008
    ..However, cortisol slope differences were significant when participants had contact with someone whom they usually saw every day. Social relationships that provide daily contact may have the strongest influence on biological rhythms...
  35. pmc Stress and inflammation in exacerbations of asthma
    Edith Chen
    University of British Columbia, Department of Psychology, 2136 West Mall, Vancouver, BC, Canada V6T 1Z4
    Brain Behav Immun 21:993-9. 2007
    ..Empirical evidence for this model is reviewed, and conclusions and future research directions are discussed...
  36. ncbi request reprint Increased serum levels of 8-hydroxy-2'-deoxyguanosine in clinical depression
    Michael J Forlenza
    Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada
    Psychosom Med 68:1-7. 2006
    ..We sought to understand the pathophysiological effects of depression by examining group differences in serum levels of 8-hydroxy-2'-deoxyguanosine (8-OHdG), a biomarker of oxidative damage...
  37. pmc The role of the social environment in children and adolescents with asthma
    Edith Chen
    Department of Psychology, University of British Columbia, Vancouver, BC, Canada
    Am J Respir Crit Care Med 176:644-9. 2007
    ..Biopsychosocial models of asthma have been proposed in the literature, but few empirical tests of social factors at various levels of influence have been conducted...
  38. ncbi request reprint Blunted cortisol response to awakening in mild to moderate depression: regulatory influences of sleep patterns and social contacts
    Cinnamon Stetler
    Department of Psychology, University of British Columbia, Vancouver, BC, Canada
    J Abnorm Psychol 114:697-705. 2005
    ..These psychosocial factors may contribute to a normal CAR, but their regulatory influence may become disrupted during mild to moderate clinical depression...
  39. ncbi request reprint Written disclosure of experiences with racial discrimination and antibody response to an influenza vaccine
    Cinnamon Stetler
    University of British Columbia, Vancouver, Canada
    Int J Behav Med 13:60-8. 2006
    ..The attributional ambiguity sometimes associated with racism may inhibit the benefits of disclosure interventions for these types of stressors...
  40. ncbi request reprint The Great Debate, revisited
    Kenneth E Freedland
    Psychosom Med 68:179-84. 2006
  41. ncbi request reprint You've gotta know when to fold 'em: goal disengagement and systemic inflammation in adolescence
    Gregory E Miller
    University of British Columbia, Vancouver, British Columbia, Canada
    Psychol Sci 18:773-7. 2007
    ..Because excessive inflammation contributes to a variety of adverse medical outcomes, these findings suggest that in some contexts, persistence may actually undermine well-being and good health...