Affiliation: Washington State University
- A novel approach to identify driver genes involved in androgen-independent prostate cancerEllyn N Schinke
Department of Pharmaceutical Sciences, Washington State University, Spokane, WA 99210 1495, USA
Mol Cancer 13:120. 2014..Here, we utilized a replication-incompetent lentiviral vector (LV) to perform an insertional mutagenesis screen to identify genes in the progression to androgen-independent prostate cancer (AIPC)...
- Amelioration of behavioral abnormalities in BH(4)-deficient mice by dietary supplementation of tyrosineSang Su Kwak
Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, South Korea
PLoS ONE 8:e60803. 2013..The present study proposes that brain mTORC1 signaling pathway is one of the potential targets in understanding abnormal motor behaviors associated with BH4-deficiency...
- Diet, nutrients, phytochemicals, and cancer metastasis suppressor genesGary G Meadows
Department of Pharmaceutical Sciences, College of Pharmacy, Washington State University, P O Box 646510, Pullman, WA 99164 6510, USA
Cancer Metastasis Rev 31:441-54. 2012..The review addresses this area of research as well as the current state of knowledge regarding the impact of diet, dietary components, and phytochemicals on metastasis suppressor genes...
- Specific amino acid deficiency alters the expression of genes in human melanoma and other tumor cell linesG G Meadows
Cancer Prevention and Research Center, Department of Pharmaceutical Sciences, College of Pharmacy, Washington State University, Pullman, WA 99164 6510, USA
J Nutr 131:3047S-50S. 2001..This study shows that tumor cells display heterogeneity in their response to deprivation of Tyr and Phe and that these amino acids may be signaling molecules that regulate gene expression and function in tumor cells...