Research Topics
| J D McPhersonSummaryAffiliation: Washington University School of Medicine Country: USA Publications
| Collaborators
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Detail Information
Publications
A radiation hybrid map of human chromosome 5 with integration of cytogenetic, genetic, and transcript mapsJ D McPherson
Department of Biological Chemistry, University of California at Irvine, 92717, USA
Genome Res 7:897-909. 1997..Together, these maps will assist in the assembly of sequence-ready contigs and will aid in the identification of disease loci on chromosome 5 by positional cloning and positional candidate approaches...- A physical map of the human genomeJ D McPherson
Washington University School of Medicine, Genome Sequencing Center, Department of Genetics, St Louis, Missouri 63108, USA
Nature 409:934-41. 2001..We also describe the integration of sequence data with the map... - MethylScreen: DNA methylation density monitoring using quantitative PCRH Holemon
Orion Genomics, LLC, St Louis, MO, USA
Biotechniques 43:683-93. 2007..Interestingly, the interpreted output from the four quantitative PCRs closely resembled the molecular population as described by clone-based bisulfite genomic sequencing... 
High throughput fingerprint analysis of large-insert clonesM A Marra
Washington University School of Medicine, Genome Sequencing Center, St Louis, Missouri 63108, USA
Genome Res 7:1072-84. 1997..We anticipate that the high throughput and precision characteristic of our fingerprinting method will make it of general utility...- A proposal to sequence the amphioxus genome submitted to the Joint Genome Institute of the US Department of EnergyJeremy J Gibson-Brown
Department of Biology, Washington University, St. Louis, Missouri 63130, USA
J Exp Zoolog B Mol Dev Evol 300:5-22. 2003 - Comprehensive DNA methylation profiling in a human cancer genome identifies novel epigenetic targetsJ M Ordway
Orion Genomics, St Louis, MO 63108, USA
Carcinogenesis 27:2409-23. 2006..Uniquely, hypermethylation of the CGI within an IRX3 exon was correlated with over-expression of IRX3 in tumor tissues and cell lines relative to normal brain samples... - The syntenic relationship of the zebrafish and human genomesW B Barbazuk
Washington University School of Medicine Genome Sequencing Center, St Louis, Missouri 63108, USA
Genome Res 10:1351-8. 2000..This work now provides a syntenic relationship to the human genome for the majority of the zebrafish genome... - Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolutionLadeana W Hillier
Genome Sequencing Center, Washington University School of Medicine, Campus Box 8501, 4444 Forest Park Avenue, St Louis, Missouri 63108, USA
Nature 432:695-716. 2004..The distinctive properties of avian microchromosomes, together with the inferred patterns of conserved synteny, provide additional insights into vertebrate chromosome architecture... - Initial sequencing and comparative analysis of the mouse genomeRobert H Waterston
Genome Sequencing Center, Washington University School of Medicine, Campus Box 8501, 4444 Forest Park Avenue, St Louis, Missouri 63108, USA
Nature 420:520-62. 2002.... - The DNA sequence of human chromosome 7Ladeana W Hillier
Genome Sequencing Center, Washington University School of Medicine, Campus Box 8501, 4444 Forest Park Avenue, St Louis, Missouri 63108, USA
Nature 424:157-64. 2003..Of genes confirmed by transcript sequences, some are polymorphic for mutations that disrupt the reading frame... - A physical map of the chicken genomeJohn W Wallis
Genome Sequencing Center, Washington University School of Medicine, Campus Box 8501, 4444 Forest Park Avenue, St Louis, Missouri 63108, USA
Nature 432:761-4. 2004..This map represents approximately 91% of the chicken genome and enables identification of chicken clones aligned to positions in other sequenced genomes... - Generation and annotation of the DNA sequences of human chromosomes 2 and 4Ladeana W Hillier
Genome Sequencing Center, Washington University School of Medicine, Campus Box 8501, 4444 Forest Park Avenue, St. Louis, Missouri 63108, USA
Nature 434:724-31. 2005..Extensive analyses confirm the underlying construction of the sequence, and expand our understanding of the structure and evolution of mammalian chromosomes, including gene deserts, segmental duplications and highly variant regions... - Massively parallel bisulphite pyrosequencing reveals the molecular complexity of breast cancer-associated cytosine-methylation patterns obtained from tissue and serum DNAYulia Korshunova
Orion Genomics, LLC, St Louis, Missouri 63108, USA
Genome Res 18:19-29. 2008..Importantly, by establishing the methylation landscape within circulating DNA, this study has better defined the development challenges facing DNA methylation-based cancer-detection tests... - Large-scale RT-PCR recovery of full-length cDNA clonesJia Qian Wu
Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
Biotechniques 36:690-6, 698-700. 2004..This systematic gene recovery pipeline allows both rescue of predicted human and rat genes and provides insight into the complexity of the transcriptome through comparisons with existing data sets... - Punctuated duplication seeding events during the evolution of human chromosome 2p11Julie E Horvath
Department of Genetics and Center for Human Genetics, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio 44106, USA
Genome Res 15:914-27. 2005..The data further indicate that factors other than sequence are important determinants for such bursts of duplicative transposition from the euchromatin to pericentromeric regions... - A physical map of the mouse genomeSimon G Gregory
The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK
Nature 418:743-50. 2002..The human sequence may be used to facilitate construction of other mammalian genome maps using the same strategy... - Integrated and sequence-ordered BAC- and YAC-based physical maps for the rat genomeMartin Krzywinski
Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, Canada V5Z 4E6
Genome Res 14:766-79. 2004..The fingerprint map is a high-resolution integrative data resource that provides genome-ordered associations among BAC, YAC, and PAC clones and the assembled sequence of the rat genome...